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Linling He

The Scripps Research Institute

28H指数
77论文数
2.3K被引数
收录论文 42
发表时间
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Single-component self-assembling protein nanoparticles displaying stabilized prefusion-closed hemagglutinin trimers for influenza vaccine development单组分自组装蛋白纳米颗粒展示稳定化的前融合-闭合血凝素三聚体，用于流感疫苗开发
errNature Communications
IF15.7
err2026-08-13
err0
errOAAI
errYi-Nan Zhang; Xueyong Zhu; Keegan Braz Gomes; Yi-Zong Lee; Connor DesRoberts; Linling He; Ian A. Wilson; Jiang Zhu
err分享
err收藏
Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification下一代丝状病毒疫苗的理性设计：结合糖蛋白稳定化与纳米颗粒展示，并辅以糖基修饰
errNature Communications
IF15.7
err2025-12-12
err0
errOAAI
errYi-Zong Lee; Yi-Nan Zhang; Maddy L. Newby; Garrett Ward; Keegan Braz Gomes; Sarah Auclair; Connor DesRoberts; Joel D. Allen; Andrew B. Ward; Robyn L. Stanfield; Linling He; Max Crispin; Ian A. Wilson; Jiang Zhu
err分享
err收藏
Metabolic Profiling Reveals Diagnostic Biomarkers for Distinguishing Myocarditis From Acute Myocardial Infarction
errCARDIOVASCULAR THERAPEUTICS
IF3.4
err2025-01-01
err0
errOAAI
errChen, Yuting; Liu, Xiu; Hong, Chengying; Xu, Shunyao; He, Linling; Liu, Zhenmi; Chen, Huaisheng; Lin, Yaowang
err分享
err收藏
Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus
errNATURE COMMUNICATIONS
IF15.7
err2024-11-16
err0
errOAAI
errLee, Yi-Zong; Han, Jerome; Zhang, Yi-Nan; Ward, Garrett; Gomes, Keegan Braz; Auclair, Sarah; Stanfield, Robyn L.; He, Linling; Wilson, Ian A.; Zhu, Jiang
err分享
err收藏
A Single-Component Multilayered Self-Assembling Protein Nanoparticle Vaccine Based on Extracellular Domains of Matrix Protein 2 against Both Influenza A and B
errVACCINES
IF3.4
err2024-08-28
err0
errOAAI
errZhang, Yi-Nan; Gomes, Keegan Braz; Lee, Yi-Zong; Ward, Garrett; Xie, Bomin; Auclair, Sarah; He, Linling; Zhu, Jiang
err分享
err收藏
Machine learning-based model to predict severe acute kidney injury after total aortic arch replacement for acute type A aortic dissection
errHELIYON
IF3.6
err2024-07-01
err1
errOAAI
errLiu, Xiaolong; Fang, Miaoxian; Wang, Kai; Zhu, Junjiang; Chen, Zeling; He, Linling; Liang, Silin; Deng, Yiyu; Chen, Chunbo
err分享
err收藏
Single-Component Multilayered Self-Assembling Protein Nanoparticles Displaying Extracellular Domains of Matrix Protein 2 as a Pan-influenza A Vaccine
errACS NANO
IF16
err2023-11-21
err7
errOAAI
errBraz Gomes, Keegan; Zhang, Yi-Nan; Lee, Yi-Zong; Eldad, Mor; Lim, Alexander; Ward, Garrett; Auclair, Sarah; He, Linling; Zhu, Jiang
err分享
err收藏
Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimmers as HIV-1 vaccine candidates
errNATURE COMMUNICATIONS
IF15.7
err2023-04-08
err25
errOAAI
errZhang, Yi-Nan; Paynter, Jennifer; Antanasijevic, Aleksandar; Allen, Joel D.; Eldad, Mor; Lee, Yi-Zong; Copps, Jeffrey; Newby, Maddy L.; He, Linling; Chavez, Deborah; Frost, Pat; Goodroe, Anna; Dutton, John; Lanford, Robert; Chen, Christopher; Wilson, Ian A.; Crispin, Max; Ward, Andrew B.; Zhu, Jiang
err分享
err收藏
Prediction of acute kidney injury after total aortic arch replacement with serum cystatin C and urine N-acetyl-β-D-glucosaminidase: A prospective observational study
errCLINICA CHIMICA ACTA
IF2.9
err2023-01-01
err7
errOAAI
errFang, Miaoxian; Li, Jiaxin; Fang, Heng; Wu, Jinlin; Wu, Zheng; He, Linling; Deng, Jia; Chen, Chunbo
err分享
err收藏
Defining a postoperative mean arterial pressure threshold in association with acute kidney injury after cardiac surgery: a prospective observational study定义与心脏手术后急性肾损伤相关的术后平均动脉压阈值: 一项前瞻性观察研究
errINTERNAL AND EMERGENCY MEDICINE
IF3.8
err2022-12-29
err4
PREAI
errHe, Linling; Liang, Silin; Liang, Yu; Fang, Miaoxian; Li, Jiaxin; Deng, Jia; Fang, Heng; Li, Ying; Jiang, Xinyi; Chen, Chunbo
err分享
err收藏
Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines (May, 10.1038/s41467-022-34108-9, 2022)
errNATURE COMMUNICATIONS
IF15.7
err2022-10-25
err1
errOAAI
errHe, Linling; Chaudhary, Anshul; Lin, Xiaohe; Sou, Cindy; Alkutkar, Tanwee; Kumar, Sonu; Ngo, Timothy; Kosviner, Ezra; Ozorowski, Gabriel; Stanfield, Robyn L.; Ward, Andrew B.; Wilson, Ian A.; Zhu, Jiang
err分享
err收藏
Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota DisturbanceIndole-3-Propionic酸作为脓毒症诱导的肠道菌群紊乱的潜在治疗剂
errMICROBIOLOGY SPECTRUM
IF3.8
err2022-06-29
err47
errOAAI
errFang, Heng; Fang, Miaoxian; Wang, Yirong; Zhang, Huidan; Li, Jiaxin; Chen, Jingchun; Wu, Qingrui; He, Linling; Xu, Jing; Deng, Jia; Liu, Mengting; Deng, Yiyu; Chen, Chunbo
err分享
err收藏
Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
errMSYSTEMS
IF4.6
err2022-06-28
err38
errOAAI
errFang, Heng; Wang, Yirong; Deng, Jia; Zhang, Huidan; Wu, Qingrui; He, Linling; Xu, Jing; Shao, Xin; Ouyang, Xin; He, Zhimei; Zhou, Qiuping; Wang, Huifang; Deng, Yiyu; Chen, Chunbo
err分享
err收藏
Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
errFRONTIERS IN MEDICINE
IF3
err2021-12-24
err5
errOAAI
errLv, Bo; Hu, Linhui; Fang, Heng; Sun, Dayong; Hou, Yating; Deng, Jia; Zhang, Huidan; Xu, Jing; He, Linling; Liang, Yufan; Chen, Chunbo
err分享
err收藏
Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants
errSCIENCE ADVANCES
IF12.5
err2021-10-22
err23
errOAAI
errZhang, Yi-Nan; Paynter, Jennifer; Sou, Cindy; Fourfouris, Tatiana; Wang, Ying; Abraham, Ciril; Ngo, Timothy; Zhang, Yi; He, Linling; Zhu, Jiang
err分享
err收藏
Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles第一代gp41-Stabilized HIV-1包膜三聚体和纳米颗粒诱导的中和抗体
errMBIO
IF4.7
err2021-06-29
err8
errOAAI
errKumar, Sonu; Lin, Xiaohe; Ngo, Timothy; Shapero, Benjamin; Sou, Cindy; Allen, Joel D.; Copps, Jeffrey; Zhang, Lei; Ozorowski, Gabriel; He, Linling; Crispin, Max; Ward, Andrew B.; Wilson, Ian A.; Zhu, Jiang
err分享
err收藏
Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines
errNATURE COMMUNICATIONS
IF15.7
err2021-05-11
err23
errOAAI
errHe, Linling; Chaudhary, Anshul; Lin, Xiaohe; Sou, Cindy; Alkutkar, Tanwee; Kumar, Sonu; Ngo, Timothy; Kosviner, Ezra; Ozorowski, Gabriel; Stanfield, Robyn L.; Ward, Andrew B.; Wilson, Ian A.; Zhu, Jiang
err分享
err收藏
Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins
errIMMUNITY
IF26.3
err2021-04-01
err26
errOAAI
errChen, Fang; Tzarum, Netanel; Lin, Xiaohe; Giang, Erick; Velazquez-Moctezuma, Rodrigo; Augestad, Elias H.; Nagy, Kenna; He, Linling; Hernandez, Mayda; Fouch, Mallorie E.; Grinyo, Ariadna; Chavez, Deborah; Doranz, Benjamin J.; Prentoe, Jannick; Stanfield, Robyn L.; Lanford, Robert; Bukh, Jens; Wilson, Ian A.; Zhu, Jiang; Law, Mansun
err分享
err收藏
Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates
errSCIENCE ADVANCES
IF12.5
err2021-03-19
err94
errOAAI
errHe, Linling; Lin, Xiaohe; Wang, Ying; Abraham, Ciril; Sou, Cindy; Ngo, Timothy; Zhang, Yi; Wilson, Ian A.; Zhu, Jiang
err分享
err收藏
A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
errSCIENCE ADVANCES
IF12.5
err2020-09-18
err21
errOAAI
errKumar, Sonu; Ju, Bin; Shapero, Benjamin; Lin, Xiaohe; Ren, Li; Zhang, Lei; Li, Dan; Zhou, Zehua; Feng, Yi; Sou, Cindy; Mann, Colin J.; Hao, Yanling; Sarkar, Anita; Hou, Jiali; Nunnally, Christian; Hong, Kunxue; Wang, Shuo; Ge, Xiangyang; Su, Bin; Landais, Elise; Sok, Devin; Zwick, Michael B.; He, Linling; Zhu, Jiang; Wilson, Ian A.; Shao, Yiming
err分享
err收藏

研究方向

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合作学者
合作期刊
I
Ian A. Wilson
H 指数: 179 · 论文数: 1.7K
D
Dennis R. Burton
H 指数: 172 · 论文数: 800
J
John R. Mascola
H 指数: 152 · 论文数: 777
A
Andrew B. Ward
H 指数: 109 · 论文数: 1.0K
R
Richard A. Lerner
H 指数: 106 · 论文数: 679
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