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IDE161, a potential first-in-class clinical candidate PARG inhibitor, selectively targets solid tumors with replication stress and DNA repair vulnerabilities Munoz, D. M.; Conway, M. E.; Nagarajan, V.; Lim, P. X.; Rao, A. A.; Shabalin, I.; Trego, K.; Ryan, J.; Choy, R.; Appel, M. J.; Teriete, P.; Zang, R.; Frey, C.; Barsanti, P.; Neilan, C. L.; White, M. A.; Maskey, R. S. 分享 收藏
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BCAT1 redox function maintains mitotic fidelity (vol 41, 111524, 2022) Francois, Liliana; Boskovic, Pavle; Knerr, Julian; He, Wei; Sigismondo, Gianluca; Schwan, Carsten; More, Tushar H.; Schlotter, Magdalena; Conway, Myra E.; Krijgsveld, Jeroen; Hiller, Karsten; Grosse, Robert; Lichter, Peter; Radlwimmer, Bernhard 分享 收藏
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BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease Harris, M.; El Hindy, M.; Usmari-Moraes, M.; Hudd, F.; Shafei, M.; Dong, M.; Hezwani, M.; Clark, P.; House, M.; Forshaw, T.; Kehoe, P.; Conway, M. E. 分享 收藏
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Novel Blood Biomarkers that Correlate with Cognitive Performance and Hippocampal Volumetry: Potential for Early Diagnosis of Alzheimer's Disease Hudd, Fred; Shiel, Anna; Harris, Matthew; Bowdler, Paul; McCann, Bryony; Tsivos, Demitra; Wearn, Alfie; Knight, Michael; Kauppinen, Risto; Coulthard, Elizabeth; White, Paul; Conway, Myra Elizabeth 分享 收藏
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The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory Dillon, Serena E.; Tsivos, Demitra; Knight, Michael; McCann, Bryony; Pennington, Catherine; Shiel, Anna I.; Conway, Myra E.; Newson, Margaret A.; Kauppinen, Risto A.; Coulthard, Elizabeth J. 分享 收藏
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Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas Conway, Myra E.; Hull, Jonathon; El Hindy, Maya; Taylor, Scott C.; El Amraoui, Farah; Paton-Thomas, Caroline; White, Paul; Williams, Maggie; Ellis, Hayley P.; Bertoni, Anna; Radlwimmer, Bernhard; Hutson, Susan M.; Kurian, Kathreena M. 分享 收藏
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Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity 阿尔茨海默氏病大脑中BCAT蛋白表达的区域增加: 谷氨酸毒性的影响 Hull, Jonathon; Patel, Vinood; El Hindy, Maya; Lee, Christopher; Odeleye, Esther; Hezwani, Mohammed; Love, Seth; Kehoe, Patrick; Chalmers, Katy; Conway, Myra 分享 收藏