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R

Ralf Langen

university of southern california

62H指数
161论文数
1.3W被引数
收录论文 89
发表时间
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Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates表位特异性抗体能够区分可溶性亨廷顿蛋白外显子-1及其多样的细胞内聚集物。
errJournal of Biological Chemistry
IF3.9
err2025-12-12
err0
errOAAI
errJoshua Lugo; Hui Xu; Jeannie Chen; Ali Khoshnan; Ralf Langen
err分享
err收藏
Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease
errNEUROBIOLOGY OF DISEASE
IF5.6
err2025-02-01
err0
errOAAI
errXu, Hui; Ajayan, Anakha; Langen, Ralf; Chen, Jeannie
err分享
err收藏
TDP43 and huntingtin Exon-1 undergo a conformationally specific interaction that strongly alters the fibril formation of both proteins
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-09-01
err1
errOAAI
errGeorge, Gincy; Ajayan, Anakha; Varkey, Jobin; Pandey, Nitin K.; Chen, Jeannie; Langen, Ralf
err分享
err收藏
RETRACTION: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system (Retraction of Vol 24, Pg 326, 2018)
errNATURE MEDICINE
IF50
err2024-04-05
err0
errOAAI
errMontagne, Axel; Nikolakopoulou, Angeliki M.; Zhao, Zhen; Sagare, Abhay P.; Si, Gabriel; Lazic, Divna; Barnes, Samuel R.; Daianu, Madelaine; Ramanathan, Anita; Go, Ariel; Lawson, Erica J.; Wang, Yaoming; Mack, William J.; Thompson, Paul M.; Schneider, Julie A.; Varkey, Jobin; Langen, Ralf; Mullins, Eric; Jacobs, Russell E.; Zlokovic, Berislav V.
err分享
err收藏
Fluorescent protein tagging promotes phase separation and alters the aggregation pathway of huntingtin exon-1
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-01-01
err5
errOAAI
errPandey, Nitin K.; Varkey, Jobin; Ajayan, Anakha; George, Gincy; Chen, Jeannie; Langen, Ralf
err分享
err收藏
Molecular basis of Q-length selectivity for the MW1 antibody-huntingtin interaction
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-04-01
err2
errOAAI
errBravo-Arredondo, Jose M.; Venkataraman, Rajashree; Varkey, Jobin; Isas, Jose Mario; Situ, Alan J.; Xu, Hui; Chen, Jeannie; Ulmer, Tobias S.; Langen, Ralf
err分享
err收藏
Lysine acetylation regulates the interaction between proteins and membranes
errNATURE COMMUNICATIONS
IF15.7
err2021-11-09
err40
errOAAI
errOkada, Alan K.; Teranishi, Kazuki; Ambroso, Mark R.; Isas, Jose Mario; Vazquez-Sarandeses, Elena; Lee, Joo-Yeun; Melo, Arthur Alves; Pandey, Priyatama; Merken, Daniel; Berndt, Leona; Lammers, Michael; Daumke, Oliver; Chang, Karen; Haworth, Ian S.; Langen, Ralf
err分享
err收藏
Amplification of neurotoxic HTTex1 assemblies in human neurons
errNEUROBIOLOGY OF DISEASE
IF5.6
err2021-11-01
err4
errOAAI
errChongtham, Anjalika; Isas, J. Mario; Pandey, Nitin K.; Rawat, Anoop; Yoo, Jung Hyun; Mastro, Tara; Kennedy, Mary B.; Langen, Ralf; Khoshnan, Ali
err分享
err收藏
Huntingtin fibrils with different toxicity, structure, and seeding potential can be interconverted
errNATURE COMMUNICATIONS
IF15.7
err2021-07-13
err26
errOAAI
errMario Isas, J.; Pandey, Nitin K.; Xu, Hui; Teranishi, Kazuki; Okada, Alan K.; Fultz, Ellisa K.; Rawat, Anoop; Applebaum, Anise; Meier, Franziska; Chen, Jeannie; Langen, Ralf; Siemer, Ansgar B.
err分享
err收藏
An Amphipathic Alpha-Helix Domain from Poliovirus 2C Protein Tubulate Lipid Vesicles
errVIRUSES-BASEL
IF3.5
err2020-12-18
err10
errOAAI
errVarkey, Jobin; Zhang, Jiantao; Kim, Junghyun; George, Gincy; He, Guijuan; Belov, George; Langen, Ralf; Wang, Xiaofeng
err分享
err收藏
Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils
errBIOPHYSICAL JOURNAL
IF3.1
err2020-11-01
err9
errOAAI
errFalk, Alexander S.; Bravo-Arredondo, Jose M.; Varkey, Jobin; Pacheco, Sayuri; Langen, Ralf; Siemer, Ansgar B.
err分享
err收藏
Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2020-06-22
err18
PREAI
errLo, Chih Hung; Pandey, Nitin K.; Lim, Colin Kin-Wye; Ding, Zhipeng; Tao, Meixin; Thomas, David D.; Langen, Ralf; Sachs, Jonathan N.
err分享
err收藏
Annexin B12 Trimer Formation is Governed by a Network of Protein-Protein and Protein-Lipid Interactions
errSCIENTIFIC REPORTS
IF3.9
err2020-03-24
err6
errOAAI
errTao, Meixin; Isas, J. Mario; Langen, Ralf
err分享
err收藏
The Mitochondrial Peptide Humanin Targets but Does Not Denature Amyloid Oligomers in Type II Diabetes
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-08-28
err18
PREAI
errLevine, Zachary A.; Teranishi, Kazuki; Okada, Alan K.; Langen, Ralf; Shea, Joan-Emma
err分享
err收藏
E46K-like -synuclein mutants increase lipid interactions and disrupt membrane selectivity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-06-01
err39
errOAAI
errRovere, Matteo; Powers, Alex E.; Jiang, Haiyang; Pitino, Julia C.; Fonseca-Ornelas, Luis; Patel, Dushyant S.; Achille, Alessandro; Langen, Ralf; Varkey, Jobin; Bartels, Tim
err分享
err收藏
The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2018-12-01
err36
errOAAI
errBravo-Arredondo, Jose M.; Kegulian, Natalie C.; Schmidt, Thomas; Pandey, Nitin K.; Situ, Alan J.; Ulmer, Tobias S.; Langen, Ralf
err分享
err收藏
Directed Supramolecular Organization of N-BAR Proteins through Regulation of H0 Membrane Immersion Depth
errSCIENTIFIC REPORTS
IF3.9
err2018-11-06
err8
errOAAI
errKahraman, Osman; Langen, Ralf; Haselwandter, Christoph A.
err分享
err收藏
Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation
errSCIENTIFIC REPORTS
IF3.9
err2018-08-03
err48
errOAAI
errTaylor, Julia R.; Fernandez, Daniel J.; Thornton, Shantae M.; Skeate, Joseph G.; Luhen, Kim P.; Da Silva, Diane M.; Langen, Ralf; Kast, W. Martin
err分享
err收藏
Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin
errHUMAN MOLECULAR GENETICS
IF3.2
err2018-04-18
err23
errOAAI
errKo, Jan; Isas, J. Mario; Sabbaugh, Adam; Yoo, Jung Hyun; Pandey, Nitin K.; Chongtham, Anjalika; Ladinsky, Mark; Wu, Wei-Li; Rohweder, Heike; Weiss, Andreas; Macdonald, Douglas; Munoz-Sanjuan, Ignacio; Langen, Ralf; Patterson, Paul H.; Khoshnan, Ali
err分享
err收藏
RETRACTED: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system (Retracted Article)
errNATURE MEDICINE
IF50
err2018-02-05
err292
errOAAI
errMontagne, Axel; Nikolakopoulou, Angeliki M.; Zhao, Zhen; Sagare, Abhay P.; Si, Gabriel; Lazic, Divna; Barnes, Samuel R.; Daianu, Madelaine; Ramanathan, Anita; Go, Ariel; Lawson, Erica J.; Wang, Yaoming; Mack, William J.; Thompson, Paul M.; Schneider, Julie A.; Varkey, Jobin; Langen, Ralf; Mullins, Eric; Jacobs, Russell E.; Zlokovic, Berislav V.
err分享
err收藏

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