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L

Lars Eckmann

university of california san diego

89H指数
346论文数
3.5W被引数
收录论文 137
发表时间
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Pharmacokinetics and transcriptomic analysis reveal the molecular signature of mucosal healing in patients with Acute Severe Ulcerative Colitis treated with infliximab (PROTOS)药代动力学和转录组学分析揭示接受英夫利昔单抗治疗的急性重度溃疡性结肠炎患者黏膜愈合的分子特征 (PROTOS)
errJournal of Crohns & Colitis
IF8.7
err2026-01-01
err0
PREAI
errBattat, R.; Massimino, L.; Lefevre, P.; Ahmed, W.; Charilaou, P.; Boland, B.; Singh, S.; Dulai, P.; Duijvestein, M.; Eckmann, L.; Silverberg, M.; Longman, R.; Lukin, D.; Scherl, E.; Rueffer, M.; Smith, M.; Filice, M.; Teft, W.; Feagan, B. G.; Sandborn, W.; Jairath, V; Casteele, N. Vande
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Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses肠道上皮PTPN2通过免疫导向的抗菌反应限制共生致病菌的定植
errGut Microbes
IF11
err2025-09-15
err0
errOAAI
errPritha Chatterjee; Marianne R. Spalinger; Charly Acevedo; Alina N. Santos; Casey M. Gries; Salomon M. Manz; Vinicius Canale; Ali Shawki; Anica Sayoc-Becerra; Hillmin Lei; Meli’sa S. Crawford; Lars Eckmann; James Borneman; Declan F. McCole
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Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease靶向抑制致病共生菌毒力因子可缓解酒精性肝病
errCell Host & Microbe
IF18.7
err2025-05-28
err0
PREAI
errYongqiang Yang; Yi Duan; Sonja Lang; Marcos F. Fondevila; David Schöler; Aenne Harberts; Noemí Cabré; Sainan Chen; Yan Shao; Kevin Vervier; Yukiko Miyamoto; Xinlian Zhang; Huikuan Chu; Ling Yang; Chen Tan; Lars Eckmann; Francisco Bosques-Padilla; Elizabeth C. Verna; Juan G. Abraldes; Robert S. Brown; Victor Vargas; Jose Altamirano; Juan Caballería; Debbie L. Shawcross; Alexandre Louvet; Michael R. Lucey; Philippe Mathurin; Guadalupe Garcia-Tsao; Ramon Bataller; Peter Stärkel; Trevor D. Lawley; Bernd Schnabl
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Evolutionary dynamics of polyadenylation signals and their recognition strategies in protists
errGENOME RESEARCH
IF5.5
err2024-09-26
err0
PREAI
errSajek, Marcin P.; Bilodeau, Danielle Y.; Beer, Michael A.; Horton, Emma; Miyamoto, Yukiko; Velle, Katrina B.; Eckmann, Lars; Fritz-Laylin, Lillian; Rissland, Olivia S.; Mukherjee, Neelanjan
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Antigiardial and antiamebic activities of fexinidazole and its metabolites: new drug leads for giardiasis and amebiasis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-01-10
err2
errOAAI
errEscrig, Jose Ignacio; Miyamoto, Yukiko; Aznar, Alejandro Delgado; Eckmann, Lars; Debnath, Anjan
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Loss of cAMP Signaling in CD11c Immune Cells Protects Against Diet-Induced Obesity
errDIABETES
IF7.5
err2023-05-31
err2
errOAAI
errZeng, Liping; Herdman, D. Scott; Lee, Sung Min; Tao, Ailin; Das, Manasi; Bertin, Samuel; Eckmann, Lars; Mahata, Sushil K.; Wu, Panyisha; Hara, Miki; Byun, Ji-Won; Devulapalli, Shwetha; Patel, Hemal H.; Molina, Anthony J. A.; Osborn, Olivia; Corr, Maripat; Raz, Eyal; Webster, Nicholas J. G.
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A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells
errANTIOXIDANTS & REDOX SIGNALING
IF6.1
err2023-01-01
err3
errOAAI
errRios-Covian, David; Butcher, Lindsay D.; Ablack, Amber L.; den Hartog, Gerco; Matsubara, Mason T.; Ly, Hong; Oates, Andrew W.; Xu, Guorong; Fisch, Kathleen M.; Ahrens, Eric T.; Toden, Shusuke; Brown, Corrie C.; Kim, Kenneth; Le, Dzung; Eckmann, Lars; Dhar, Bithika; Izumi, Tadahide; Ernst, Peter B.; Crowe, Sheila E.
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PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2023-01-01
err5
errOAAI
errCanale, Vinicius; Spalinger, Marianne R.; Alvarez, Rocio; Sayoc-Becerra, Anica; Sanati, Golshid; Manz, Salomon; Chatterjee, Pritha; Santos, Alina N.; Lei, Hillmin; Jahng, Sharon; Chu, Timothy; Shawki, Ali; Hanson, Elaine; Eckmann, Lars; Ouellette, Andre J.; McCole, Declan F.
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Conserved metabolic enzymes as vaccine antigens for giardiasis
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2022-04-25
err4
errOAAI
errIhara, Sozaburo; Miyamoto, Yukiko; Le, Christine H. Y.; Tran, Vivien N.; Hanson, Elaine M.; Fischer, Marvin; Hanevik, Kurt; Eckmann, Lars
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The fecal mycobiome in non-alcoholic fatty liver disease非酒精性脂肪性肝病的粪便真菌生物组
errJOURNAL OF HEPATOLOGY
IF33
err2022-04-01
err95
errOAAI
errDemir, Munevver; Lang, Sonja; Hartmann, Phillipp; Duan, Yi; Martin, Anna; Miyamoto, Yukiko; Bondareva, Marina; Zhang, Xinlian; Wang, Yanhan; Kasper, Philipp; Bang, Corinna; Roderburg, Christoph; Tacke, Frank; Steffen, Hans-Michael; Goeser, Tobias; Kruglov, Andrey; Eckmann, Lars; Starkel, Peter; Fouts, Derrick E.; Schnabl, Bernd
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Codelivery of Antigens and Adjuvant in Polymeric Nanoparticles Coated With Native Parasite Membranes Induces Protective Mucosal Immunity Against Giardia lamblia
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2022-03-09
err6
errOAAI
errZhou, Jiarong; Miyamoto, Yukiko; Ihara, Sozaburo; Kroll, Ashley, V; Nieskens, Noelle; Tran, Vivien N.; Hanson, Elaine M.; Fang, Ronnie H.; Zhang, Liangfang; Eckmann, Lars
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Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2022-02-10
err18
errOAAI
errKrakovka, Sascha; Ribacke, Ulf; Miyamoto, Yukiko; Eckmann, Lars; Svard, Staffan
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Colesevelam ameliorates non-alcoholic steatohepatitis and obesity in mice
errHEPATOLOGY INTERNATIONAL
IF6.1
err2022-01-24
err19
errOAAI
errHartmann, Phillipp; Duan, Yi; Miyamoto, Yukiko; Demir, Munevver; Lang, Sonja; Hasa, Elda; Stern, Patrick; Yamashita, Dennis; Conrad, Mary; Eckmann, Lars; Schnabl, Bernd
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Metabolomics activity screening of T cell-induced colitis reveals anti-inflammatory metabolites
errSCIENCE SIGNALING
IF6.6
err2021-09-28
err21
errOAAI
errMontenegro-Burke, J. Rafael; Kok, Bernard P.; Guijas, Carlos; Domingo-Almenara, Xavier; Moon, Clara; Galmozzi, Andrea; Kitamura, Seiya; Eckmann, Lars; Saez, Enrique; Siuzdak, Gary E.; Wolan, Dennis W.
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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2021-09-01
err23
errOAAI
errMarchelletta, Ronald R.; Krishnan, Moorthy; Spalinger, Marianne R.; Placone, Taylaur W.; Alvarez, Rocio; Sayoc-Becerra, Anica; Canale, Vinicius; Shawki, Ali; Park, Young Su; Bernts, Lucas H. P.; Myers, Stephen; Tremblay, Michel L.; Barrett, Kim E.; Krystofiak, Evan; Kachar, Bechara; McGovern, Dermot P. B.; Weber, Christopher R.; Hanson, Elaine M.; Eckmann, Lars; McCole, Declan F.
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Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia微生物群调节心脏对间歇性缺氧和高碳酸血症的转录反应
errFRONTIERS IN PHYSIOLOGY
IF3.4
err2021-06-25
err6
errOAAI
errZhou, Dan; Xue, Jin; Miyamoto, Yukiko; Poulsen, Orit; Eckmann, Lars; Haddad, Gabriel G.
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Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-05-11
err10
errOAAI
errMiyamoto, Yukiko; Aggarwal, Shubhangi; Celaje, Jeff Joseph A.; Ihara, Sozaburo; Ang, Jonathan; Eremin, Dmitry B.; Land, Kirkwood M.; Wrischnik, Lisa A.; Zhang, Liangfang; Fokin, Valery V.; Eckmann, Lars
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Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis去氮嘌呤核苷类似物治疗阴道毛滴虫
errACS INFECTIOUS DISEASES
IF3.8
err2021-05-11
err16
errOAAI
errNatto, Manal J.; Hulpia, Fabian; Kalkman, Eric R.; Baillie, Susan; Alhejeli, Amani; Miyamoto, Yukiko; Eckmann, Lars; Van Calenbergh, Serge; de Koning, Harry P.
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Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2021-02-02
err7
errOAAI
errden Hartog, Gerco; Butcher, Lindsay D.; Ablack, Amber L.; Pace, Laura A.; Ablack, Jailal N. G.; Xiong, Richard; Das, Soumita; Stappenbeck, Thaddeus S.; Eckmann, Lars; Ernst, Peter B.; Crowe, Sheila E.
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The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites
errMICROBIAL GENOMICS
IF4
err2020-08-01
err26
errOAAI
errXu, Feifei; Jimenez-Gonzalez, Alejandro; Einarsson, Elin; Astvaldsson, Asgeir; Peirasmaki, Dimitra; Eckmann, Lars; Andersson, Jan O.; Svard, Staffan G.; Jerlstrom-Hultqvist, Jon
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研究方向

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