未登录 Functional differences between CLL- and ALL-derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL-10 as potential modulatory targets CLL和ALL来源的CAR T细胞在3D肿瘤微环境中的功能差异突出了CXCR4和IL-10作为潜在的调节靶点。 Dingfelder, Janin; Aigner, Michael; Lindacher, Jana; Lukas, Pascal; Flamann, Cindy; Nusser, Gina; Zimmermann, Katharina; Schambach, Axel; Graw, Frederik; Volkl, Simon; Bruns, Heiko; Krumbholz, Manuela; Haibach, Martina; Wilke, Jochen; Mackensen, Andreas; Lutzny-geier, Gloria 分享 收藏
CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis CD19 CAR T细胞疗法在多药耐药性溃疡性结肠炎中的应用 Mueller, Fabian; Atreya, Raja; Voelkl, Simon; Aigner, Michael; Kretschmann, Sascha; Kharboutli, Soraya; Leppkes, Moritz; Sitte, Selina; Strobel, Deike; Hartmann, Arndt; Mehandru, Saurabh; Colombel, Jean-Frederic; Schett, Georg; Mackensen, Andreas; Neurath, Markus F. 分享 收藏
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BCMA CAR T cells in a patient with relapsing idiopathic inflammatory myositis after initial and repeat therapy with CD19 CAR T cells BCMA CAR T细胞在一名接受初始及重复CD19 CAR T细胞疗法的复发性特发性炎性肌病患者中的表现 Mueller, Fabian; Wirsching, Andreas; Hagen, Melanie; Voelkl, Simon; Tur, Carlo; Raimondo, Maria Gabriella; Taubmann, Jule; Bucci, Laura; Zhang, Liang; Kretschmann, Sascha; Aigner, Michael; Spoerl, Silvia; Kharboutli, Soraya; Boeltz, Sebastian; Atzinger, Armin; Munoz, Luis; Schett, Georg; Mackensen, Andreas; Grieshaber-Bouyer, Ricardo 分享 收藏
The Tumor Metabolite 5′-Deoxy-5′Methylthioadenosine (MTA) Inhibits Maturation and T Cell-Stimulating Capacity of Dendritic Cells Brummer, Christina; Singer, Katrin; Henrich, Frederik; Peter, Katrin; Strobl, Carolin; Neueder, Bernadette; Bruss, Christina; Renner, Kathrin; Pukrop, Tobias; Herr, Wolfgang; Aigner, Michael; Kreutz, Marina 分享 收藏
EFFICACY OF CD19-TARGETING CAR T CELL TREATMENT IN PATIENTS WITH DIFFUSE SYSTEMIC SCLEROSIS (dSSc) - AN OPEN LABEL, SINGLE-CENTER PILOT STUDY CD19靶向CAR T细胞治疗在弥漫性系统性硬化症(dSSc)患者中的疗效——一项开放标签、单中心试点研究 Auth, J.; Mueller, F.; Taubmann, J.; Voelkl, S.; Fakhouri, S. Chenguiti; Bucci, L.; Aigner, M.; Atzinger, A.; Bayerl, N.; Wirsching, A.; Dees, C.; Raimondo, M. G.; Tur, C.; Distler, J.; Mackensen, A.; Schett, G.; Bergmann, C. 分享 收藏
LONG-TERM SAFETY AND EFFICACY OF CAR-T CELL TREATMENT IN SEVERE AND TREATMENT REFRACTORY AUTOIMMUNE DISEASE CAR-T细胞治疗在严重且治疗难治性自身免疫性疾病中的长期安全性与有效性 Taubmann, J.; Mueller, F.; Fagni, F.; Bergmann, C.; Tur, C.; Bucci, L.; Voelki, S.; Aigner, M.; Hagen, M.; Grieshaber-Bouyer, R.; Mougiakakos, D.; Kroenke, G.; Korganow, A. S.; Farge, D.; Bozec, A.; Mackensen, A.; Schett, G. 分享 收藏
Fully Human Anti-CD19 CAR T Cells Derived from Systemic Lupus Erythematosus Patients Exhibit Cytotoxicity with Reduced Inflammatory Cytokine Production Dingfelder, Janin; Aigner, Michael; Taubmann, Jule; Minopoulou, Ioanna; Park, Soo; Kaplan, Charles D.; Cheng, Joseph K.; Van Blarcom, Tom; Schett, Georg; Mackensen, Andreas; Lutzny-Geier, Gloria 分享 收藏
CART-cell therapy rescues adolescent with rapidly progressive lupus nephritis from haemodialysis CART细胞疗法可通过血液透析挽救患有快速进展性狼疮性肾炎的青少年 Krickau, Tobias; Naumann-Bartsch, Nora; Aigner, Michael; Kharboutli, Soraya; Kretschmann, Sascha; Spoerl, Silvia; Vasova, Ingrid; Voelkl, Simon; Woelfle, Joachim; Mackensen, Andreas; Schett, Georg; Metzler, Markus; Mueller, Fabian 分享 收藏
Preclinical development of CAR T cells with antigen-inducible IL-18 enforcement to treat GD2-positive solid cancers Fischer-Riepe, Lena; Kailayangiri, Sareetha; Zimmermann, Katharina; Pfeifer, Rita; Aigner, Michael; Altvater, Bianca; Kretschmann, Sascha; Voelkl, Simon; Hartley, Jordan; Dreger, Celine; Petry, Katja; Bosio, Andreas; von Doellen, Angelika; Hartmann, Wolfgang; Lode, Holger; Goerlich, Dennis; Mackensen, Andreas; Jungblut, Melanie; Schambach, Axel; Abken, Hinrich; Rossig, Claudia 分享 收藏
Detection of signature double-negative T cells is a predictive marker to identify autoimmune lymphoproliferative syndrome associated with FAS loss of function Eisenhauer, Nina; Miano, Maurizio; Naumann-Bartsch, Nora; Leyh, Joerg; Dell'Orso, Gianluca; Aigner, Michael; Fecker, Gisela; Hinze, Claas; Wittkowski, Helmut; Bruns, Heiko; Zierk, Jakob; Metzler, Markus; Arkwright, Peter D.; Graw, Frederik; Mackensen, Andreas; Voelkl, Simon 分享 收藏
CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up 自身免疫性疾病的CD19 CAR T细胞治疗-病例系列随访 Mueller, Fabian; Taubmann, Jule; Bucci, Laura; Wilhelm, Artur; Bergmann, Christina; Voelkl, Simon; Aigner, Michael; Rothe, Tobias; Minopoulou, Ioanna; Tur, Carlo; Knitza, Johannes; Kharboutli, Soraya; Kretschmann, Sascha; Vasova, Ingrid; Spoerl, Silvia; Reimann, Hannah; Munoz, Luis; Gerlach, Roman G.; Schaefer, Simon; Grieshaber-Bouyer, Ricardo; Korganow, Anne-Sophie; Farge-Bancel, Dominique; Mougiakakos, Dimitrios; Bozec, Aline; Winkler, Thomas; Kroenke, Gerhard; Mackensen, Andreas; Schett, Georg 分享 收藏
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Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: results from the randomized phase I/IIa MULTIVIR-01 study Gerbitz, Armin; Gary, Regina; Aigner, Michael; Moosmann, Andreas; Kremer, Anita; Schmid, Christoph; Hirschbuehl, Klaus; Wagner, Eva; Hauptrock, Beate; Teschner, Daniel; Roesler, Wolf; Spriewald, Bernd; Tischer, Johanna; Moi, Stephanie; Balzer, Heidi; Schaffer, Stefanie; Bausenwein, Judith; Wagner, Anja; Schmidt, Franziska; Brestrich, Jens; Ullrich, Barbara; Maas, Stefanie; Herold, Susanne; Strobel, Julian; Zimmermann, Robert; Weisbach, Volker; Hansmann, Leo; Lammoglia-Cobo, Fernanda; Remberger, Mats; Stelljes, Matthias; Ayuk, Francis; Zeiser, Robert; Mackensen, Andreas 分享 收藏
Influence of microstructure on degradation of cast graphitic high-speed steel Aigner, Michael; Pellizzari, Massimo; Domitner, Josef; Elizondo, Leonel; Fischbacher, Martina; Laubichler, Ingrun; Paar, Armin; Reiter, Maximilian; Trickl, Thomas; Sommitsch, Christof 分享 收藏
Cellular and humoral immune responses to SARS-CoV-2 vaccination in patients after CD19.CAR T-cell therapy Reimann, Hannah; Kremer, Anita N.; Blumenberg, Viktoria; Schmidt, Katja; Aigner, Michael; Jacobs, Benedikt; Eisenhauer, Nina; Kaempf, Alina; Roesler, Wolf; Kharboutli, Soraya; Mougiakakos, Dimitrios; Lang, Vanessa; Lischer, Christopher; Irrgang, Pascal; Leppkes, Moritz; Gonzalez, Julio Vera; Kroenke, Gerhard; Kremer, Andreas E.; Tenbusch, Matthias; Bruns, Heiko; Harrer, Thomas; Mueller, Fabian; Schett, Georg; Mackensen, Andreas; Subklewe, Marion; Voelkl, Simon 分享 收藏
CD19-targeted CAR T cells in refractory antisynthetase syndrome CD19-targeted CAR T细胞在难治性抗合成酶综合征中的作用 Mueller, Fabian; Boeltz, Sebastian; Knitza, Johannes; Aigner, Michael; Voelkl, Simon; Kharboutli, Soraya; Reimann, Hannah; Taubmann, Jule; Kretschmann, Sascha; Roesler, Wolf; Manger, Bernhard; Wacker, Jochen; Mougiakakos, Dimitrios; Jabari, Samir; Schroeder, Rolf; Uder, Michael; Roemer, Frank; Kroenke, Gerhard; Mackensen, Andreas; Schett, Georg 分享 收藏
Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus Kretschmann, S.; Voelkl, S.; Reimann, H.; Kroenke, G.; Schett, G.; Achenbach, S.; Lutzny-Geier, G.; Mueller, F.; Mougiakakos, D.; Dingfelder, J.; Flamann, C.; Hanssens, L.; Gary, R.; Mackensen, A.; Aigner, M. 分享 收藏
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