Dan L. Sackett - Publications, H-index & Citations

Dan L. Sackett

eunice kennedy shriver national institute of child health and human development and national institutes of health

48H指数

321论文数

9.9K被引数

收录论文 96

发表时间

Single-Cell Imaging of Mitochondrial Metabolism and Remodeling in C2C12 Murine Skeletal Muscle Cells upon Differentiation C2C12小鼠骨骼肌细胞分化过程中线粒体代谢与重塑的单细胞成像

International Journal of Molecular Sciences

IF4.9

2026-05-23

OAAI

Rozhin Penjweini; Alessandra Pasut; Branden Roarke; Katie A. Link; Dan L. Sackett; Jay R. Knutson

In vitro effects of Taurine on Taxol-induced mitochondrial dysfunction 牛磺酸对紫杉醇诱导的线粒体功能障碍的体外效应

MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES XXVI

IF0

2026-01-01

PREAI

Penjweini, Rozhin; Link, Katie A.; Su, Jasmine; Sackett, Dan L.; Knutson, Jay R.

gDAIS: A Global Analysis Application for Obtaining Confidence in FLIM gDAIS：一种用于提高FLIM置信度的全局分析应用

MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES XXVI

IF0

2026-01-01

PREAI

Mattu, Nikhil; Su, Jasmine; Yonas, Siem; Liu, Yuyi; Alspaugh, Greg; Qazi, Shureed; Slamani, Ayman; Link, Katie A.; Penjweini, Rozhin; Combs, Christian A.; Sackett, Dan; Knutson, Jay R.

Deconstruction of Desacetamidocolchicine's B Ring Reveals a Class 3 Atropisomeric AC Ring with Tubulin Binding Properties 去乙酰胺秋水仙碱B环的解构揭示了一种具有微管结合特性的类3阿托普异构体AC环

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2025-05-27

OAAI

Bejcek, Lauren P.; Eli, Orugbani S.; Kapkayeva, Diana M.; Nafie, Jordan; Beutler, John A.; Gallicchio, Emilio; Sackett, Dan L.; Murelli, Ryan P.

Low dose Taxol causes mitochondrial dysfunction in actively respiring cancer cells 低剂量Taxol导致活跃呼吸的癌细胞线粒体功能障碍

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-05-01

OAAI

Penjweini, Rozhin; Link, Katie A.; Qazi, Shureed; Mattu, Nikhil; Zuchowski, Adam; Vasta, Alexandra; Sackett, Dan L.; Knutson, Jay R.

Structure of blood cell-specific tubulin and demonstration of dimer spacing compaction in a single protofilament

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-02-01

OAAI

Montecinos, Felipe; Eren, Elif; Watts, Norman R.; Sackett, Dan L.; Wingfield, Paul T.

Intermolecular Oxidopyrylium (5+2) Cycloaddition/Reductive Ring-Opening Strategy for the Synthesis of α-Methoxytropones

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2024-11-12

OAAI

Eli, Orugbani S.; Bejcek, Lauren P.; Lyubimova, Anastasiya; Sackett, Dan L.; Murelli, Ryan P.

Linear (-)-Zampanolide: Flexibility in Conformation-Activity Relationships

CHEMMEDCHEM

IF3.4

2023-08-10

OAAI

Umana, Christian A.; Henry, Jeffrey L.; Saltzman, Claire T.; Sackett, Dan L.; Jenkins, Lisa M.; Taylor, Richard E.

CLIP-170S is a microtubule plus TIP variant that confers resistance to taxanes by impairing drug-target engagement

DEVELOPMENTAL CELL

IF8.7

2021-12-01

OAAI

Thakkar, Prashant, V; Kita, Katsuhiro; Del Castillo, Urko; Galletti, Giuseppe; Madhukar, Neel; Navarro, Elena Vila; Barasoain, Isabel; Goodson, Holly, V; Sackett, Dan; Diaz, Jose Fernando; Lu, Yao; RoyChoudhury, Arindam; Molina, Henrik; Elemento, Olivier; Shah, Manish A.; Giannakakou, Paraskevi

Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-10-01

OAAI

Eren, Elif; Watts, Norman R.; Sackett, Dan L.; Wingfield, Paul T.

Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma

MOLECULAR CANCER THERAPEUTICS

IF5.5

2021-02-05

OAAI

Kowalczyk, Joshua T.; Wan, Xiaolin; Hernandez, Edjay R.; Luo, Ruibai; Lyons, Gaelyn C.; Wilson, Kelli M.; Gallardo, Devorah C.; Isanogle, Kristine A.; Robinson, Christina M.; Mendoza, Arnulfo; Heske, Christine M.; Chen, Jinqui-Qiu; Luo, Xiaoling; Kelly, Alexander E.; Difilippantinio, Simone; Robey, Robert W.; Thomas, Craig J.; Sackett, Dan L.; Morrison, Deborah K.; Randazzo, Paul A.; Jenkins, Lisa M. Miller; Yohe, Marielle E.

Systems biology identifies Gleevec as a specific inhibitor of CLIP-170S, a novel plus TIP isoform, which causes taxane resistance in cancer cells and patients by obstructing the Microtubule pore

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Thakkar, Prashant, V; Kita, Katsuhiro; Galletti, Giuseppe; Madhukar, Neel; Navarro, Elena Vila; Cleveland, Kyle; Barasoain, Isabel; Goodson, Holly, V; Sackett, Dan; Fernando Diaz, Jose; Elemento, Olivier; Shah, Manish A.; Giannakakou, Paraskevi

Taurine Is Covalently Incorporated into Alpha-Tubulin 牛磺酸共价结合到 α-微管蛋白中

JOURNAL OF PROTEOME RESEARCH

IF3.6

2020-05-13

OAAI

Olson, Matthew T.; Yergey, Alfred L.; Mukherjee, Kamalika; Pergande, Melissa R.; Bane, Susan L.; Cologna, Stephanie M.; Sackett, Dan L.

All tubulins are not alike: Heterodimer dissociation differs among different biological sources

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-06-01

OAAI

Montecinos-Franjola, Felipe; Chaturvedi, Sumit K.; Schuck, Peter; Sackett, Dan L.

Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle (vol 28, pg 1117, 2019)

HUMAN MOLECULAR GENETICS

IF3.2

2019-02-11

OAAI

Randazzo, Davide; Khalique, Umara; Belanto, Joseph J.; Kenea, Aster; Talsness, Dana M.; Olthoff, John T.; Tran, Michelle D.; Zaal, Kristien J.; Pak, Katherine; Pinal-Fernandez, Iago; Mammen, Andrew L.; Sackett, Dan; Ervasti, James M.; Ralston, Evelyn

Intracellular Analysis of Individual Cells and Organelles for Both Oxygen Concentration/Consumption and NADH Free/Bound Redox State using Fluorescence Lifetime Imaging

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

PREAI

Penjweini, Rozhin; Andreoni, Alessio; Gevorgyan, Anahit; Sackett, Dan L.; Knutson, Jay R.

Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models 靶向线粒体己糖激酶可提高组蛋白去乙酰化酶抑制剂在实体瘤模型中的疗效

EXPERIMENTAL CELL RESEARCH

IF3.5

2019-02-01

OAAI

McDonald, Andrew J.; Curt, Katherine M.; Patel, Ruchi P.; Kozlowski, Hanna; Sackett, Dan L.; Robey, Robert W.; Gottesman, Michael M.; Bates, Susan E.

Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle

HUMAN MOLECULAR GENETICS

IF3.2

2018-12-06

OAAI

Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1

NATURE COMMUNICATIONS

IF15.7

2018-11-09

OAAI

Suen, Linda M.; Tekle-Smith, Makeda A.; Williamson, Kevin S.; Infantine, Joshua R.; Reznik, Samuel K.; Tanis, Paul S.; Casselman, Tyler D.; Sackett, Dan L.; Leighton, James L.

Intracellular oxygen mapping using a myoglobin-mCherry probe with fluorescence lifetime imaging

JOURNAL OF BIOMEDICAL OPTICS

IF2.9

2018-10-08

OAAI

Penjweini, Rozhin; Andreoni, Alessio; Rosales, Tilman; Kim, Jeonghan; Brenner, Michael D.; Sackett, Dan L.; Chung, Jay H.; Knutson, Jay R.

研究方向