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Yves Pommier

NIH
H指数:138
被引数:7.9万

个人简介

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荣誉奖项

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Topoisomerase III-beta protects from immune dysregulation and tumorigenesis

拓扑异构酶iii-beta保护免疫失调和肿瘤发生

SCIENCE ADVANCES
IF12.5
2025-12-190
PRE
Al Mahmud, Md Rasel; Baechler, Simone Andrea; Dhall, Anjali; Saha, Sourav; Zhang, Hongliang; Bassel, Laura; Zhang, Shuling; Lee, Min-Jung; Sato, Nahoko; Rastogi, Shraddha; Kumar, Suresh; Alam, Muhammad S.; Saha, Liton Kumar; Mock, Beverly A.; Factor, Valentina M.; Pommier, Yves
Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling

针对晚期实体瘤的肿瘤靶向拓扑异构酶i抑制剂递送与优化PARP抑制：一种间隔给药方案的i期临床试验

Nature Communications
IF15.7
2025-10-270
OAAI
Anish Thomas; Nobuyuki Takahashi; Lenka Oplustil O’Connor; Christophe E. Redon; Chirayu Mohindroo; Linda Sciuto; Lorinc Pongor; Keith T. Schmidt; Seth M. Steinberg; Mirit I. Aladjem; William Douglas Figg; Mark J. O’Connor; Yves Pommier
Metastatic Organotropism in Small Cell Lung Cancer

小细胞肺癌的转移性器官趋向性

Journal of Thoracic Oncology
IF20.8
2025-08-290
PRE
Manan Krishnamurthy; Anjali Dhall; Sarthak Sahoo; Christopher W. Schultz; Michelle A. Baird; Parth Desai; Jacob Odell; Nobuyuki Takahashi; Michael Nirula; Sophie Zhuang; Yue Huang; Brett Schroeder; Yang Zhang; Maria Sebastian Thomas; Christophe Redon; Christina Robinson; Lai Thang; Lilia Ileva; Nimit L. Patel; Joseph D. Kalen; Alice-Anaïs Varlet; Noam Zuela-Sopilniak; Ankita Jha; Darawalee Wangsa; Donna Butcher; Tamara Morgan; Alyah N. Afzal; Raj Chari; Karim Baktiar; Suresh Kumar; Lorinc Pongor; Simone Difilippantonio; Mirit I. Aladjem; Yves Pommier; Mohit Kumar Jolly; Jan Lammerding; Ajit Kumar Sharma; Anish Thomas
Discovery of Thiacyanine Dyes as a New Class of Potent Coronavirus Inhibitors that Suppress Viral RNA Synthesis

硫代菁染料作为一类新的强效冠状病毒抑制剂，可抑制病毒RNA合成

Journal of Biological Chemistry
IF3.9
2025-08-050
OA
Tianyi Zhang; Valerie Altouma; Joshua A. Sommers; Adaira J. Dumm; Debbie Kennedy; Hongjie Xia; Mo Yang; Christopher R. Fullenkamp; Shar-yin N. Huang; Yutong Xue; Shuaikun Su; Weiping Shen; Caitlin E. Haren; Tomasz Kulikowicz; Yves Pommier; John S. Schneekloth; Mariano A. Garcia-Blanco; Robert M. Brosh; Weidong Wang
Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas

I期研究评估吲哚异喹啉类化合物LMP776和LMP744在实体瘤和淋巴瘤患者中的应用

Cancer Chemotherapy and Pharmacology
IF2.3
2025-05-290
OAAI
Geraldine O’Sullivan Coyne; Shivaani Kummar; Larry V. Rubinstein; Deborah Wilsker; Nancy Moore; Murielle Hogu; Richard Piekarz; Joe Covey; Jan H. Beumer; Katherine V. Ferry-Galow; Liza C. Villaruz; Melinda G. Hollingshead; Julianne L. Holleran; Joshua J. Deppas; Yves Pommier; Brian Ko; Barry C. Johnson; Ralph E. Parchhment; Percy Ivy; James H. Doroshow; Alice P. Chen
Furanoheliangolides from Centratherum punctatum and a General Approach for Stereochemical Assignment of Flexible Chiral Side Chains

Centratherum punctatum中的呋喃海利昂醇类化合物及其柔性手性侧链立体化学构型的一般性分析方法

JOURNAL OF NATURAL PRODUCTS
IF3.6
2025-05-220
PRE
Quan T. Khong; Lindsay Marron; Shar-Yin Naomi Huang; Masoumeh Dalilian; Sourav Saha; Ekaterina I. Goncharova; Girma M. Woldemichael; Yves Pommier; Barry R. O’Keefe; Brice A. P. Wilson; Lin Du
Synthesis of 5,9-and 5,8-Diaminoalkoxy Substituted Benzophenanthridinone Analogues as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors and Their Radiosensitizing Activity

5,9-和5,8-二氨基烷氧基取代的苯并phenanthridinone类似物的合成及其作为酪氨酰-DNA焦磷酸酶1抑制剂的放射增敏活性

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-04-290
PRE
Hu, De-Xuan; Qin, Chao; Guo, Li-Shuang; Liu, Wen-Ya; Liang, Zi-Qiong; Cao, Ye; Yao, Chuan-Sheng; Wei, Yingqi; Yue, Xin; Al Mahmud, Md Rasel; Agama, Keli; Wang, Huaiming; Pommier, Yves; An, Lin-Kun
Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge Artemisina plumosa

揭示棕榈酸作为人拓扑异构酶1B抑制剂的机制，该抑制剂来源于南极海绵Artemisina plumosa

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
2025-02-261
OA
Ottaviani, Alessio; Pietrafesa, Davide; Soren, Bini Chhetri; Dasari, Jagadish Babu; Olsen, Stine S. H.; Messina, Beatrice; Demofonti, Francesco; Chicarella, Giulia; Agama, Keli; Pommier, Yves; della Rocca, Blasco Morozzo; Iacovelli, Federico; Romeo, Alice; Falconi, Mattia; Baker, Bill J.; Fiorani, Paola
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery

通过调节microRNA加工机制发挥作用的新型抗卵巢癌喹诺酮衍生物

RSC MEDICINAL CHEMISTRY
IF3.6
2025-01-011
OAAI
Felicetti, Tommaso; Di Iacovo, Nicola; Della Fazia, Maria Agnese; Piobbico, Danilo; Pieroni, Stefania; Pacetti, Martina; Yu, Jialing; Sun, Yilun; Massari, Serena; Barreca, Maria Letizia; Sabatini, Stefano; Tabarrini, Oriana; Cecchetti, Violetta; Wang, Fei; Pommier, Yves; Morlando, Mariangela; Servillo, Giuseppe; Manfroni, Giuseppe
Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

Schlafen 11通过复制叉后面的单链DNA缺口积累进一步使BRCA缺陷细胞对PARP抑制剂敏感

ONCOGENE
IF7.3
2024-07-032
OAAI
Onji, Hiroshi; Tate, Sota; Sakaue, Tomohisa; Fujiwara, Kohei; Nakano, Shiho; Kawaida, Miho; Onishi, Nobuyuki; Matsumoto, Takashi; Yamagami, Wataru; Sugiyama, Takashi; Higashiyama, Shigeki; Pommier, Yves; Kobayashi, Yusuke; Murai, Junko

研究方向

暂未获取到该数据
C
Christophe Marchand
H 指数:62论文数:249被引数:1.3万
K
Keli Agama
H 指数:41论文数:150被引数:4,083
W
William C. Reinhold
H 指数:55论文数:499被引数:1.4万
M
Mark Cushman
H 指数:58论文数:315被引数:9,813
J
Junko Murai
H 指数:41论文数:276被引数:8,266
T
Terrence R. Burke
H 指数:63论文数:470被引数:1.4万
J
James H. Doroshow
H 指数:97论文数:1,410被引数:3.7万
G
Glenda Kohlhagen
H 指数:46论文数:115被引数:6,055
S
Shar-yin N. Huang
H 指数:23论文数:99被引数:2,766
K
Kurt W. Kohn
H 指数:95论文数:433被引数:3.1万