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Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers Carroll, Christopher L.; Johnson, Michael G.; Ding, Yanbing; Kang, Zhijun; Vijayan, R. S. K.; Bardenhagen, Jennifer P.; Fang, Cheng; Lapointe, David; Li, Meng; Liu, Chiu-Yi; Lv, Xiaobing; Ma, Xiaoyan; Pang, Jihai; Shepard, Hannah E.; Suarez, Catalina; Yau, Anne Ju; Williams, Christopher C.; Wu, Qi; Heald, Robert A.; Robinson, Helen M. R.; Smith, Graeme C. M.; Cross, Jason B.; Do, Mary K. Geck; Jiang, Yongying; Lively, Sarah; Yap, Timothy A.; Giuliani, Virginia; Heffernan, Timothy; Jones, Philip; Di Francesco, M. Emilia 分享 收藏
Development of the cervical myelopathy severity index: a new patient reported outcome measure to quantify impairments and functional limitations 颈椎病严重程度指数的发展: 一种新的患者报告的结果指标,用于量化损伤和功能限制 Malhotra, Armaan K.; He, Yingshi; Harrington, Erin M.; Jaja, Blessing N. R.; Zhu, Mary P.; Shakil, Husain; Dea, Nicolas; Weber, Michael H.; Attabib, Najmedden; Phan, Philippe; Rampersaud, Yoga Raja; Paquet, Jerome; Jacobs, W. Bradley; Cadotte, David W.; Christie, Sean D.; Nataraj, Andrew; Bailey, Christopher S.; Johnson, Michael; Fisher, Charles; Hall, Hamilton; Manson, Neil; Thomas, Kenneth; Ginsberg, Howard J.; Fehlings, Michael G.; Witiw, Christopher D.; Davis, Aileen M.; Wilson, Jefferson R. 分享 收藏
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Determining minimal clinically important difference estimates following surgery for degenerative conditions of the lumbar spine: analysis of the Canadian Spine Outcomes and Research Network (CSORN) registry Power, J. Denise; Perruccio, Anthony, V; Canizares, Mayilee; Mcintosh, Greg; Abraham, Edward; Attabib, Najmedden; Bailey, Christopher S.; Charest-Morin, Raphaele; Dea, Nicholas; Finkelstein, Joel; Fisher, Charles; Glennie, R. Andrew; Hall, Hamilton; Johnson, Michael G.; Kelly, Adrienne M.; Kingwell, Stephen; Manson, Neil; Nataraj, Andrew; Paquet, Jerome; Singh, Supriya; Soroceanu, Alex; Thomas, Kenneth C.; Weber, Michael H.; Rampersaud, Y. Raja 分享 收藏
The ATR inhibitor ART0380 shows preclinical efficacy in monotherapy or in combination with gemcitabine, aPD1, PARP inhibitors and topoisomerase 1 poisons Majithiya, Jayesh Bhanabhai; Luzarraga, Marina Roy; Newman, Richard; Costales, Paula; Jones, Philip; Di Francesco, Maria Emilia; Giuliani, Virginia; Caroll, Chris; Do, Mary Geck; Heffernan, Tim; Feng, Ningpeng; Ma, XiaoYan; Lively, Sarah; Johnson, Michael G.; Geo, Lerin; Piscitello, Desiree; Rajendra, Eeson; Grinkevich, Vera; Ranzani, Marco; Stockley, Martin; Langford, Gillian; Heald, Robert; Robinson, Helen M.; Smith, Graeme C. 分享 收藏
Cost consequence analysis of waiting for lumbar disc herniation surgery Dandurand, Charlotte; Mashayekhi, Mohammad Sadegh; McIntosh, Greg; Singh, Supriya; Paquet, Jerome; Chaudhry, Hasaan; Abraham, Edward; Bailey, Christopher S.; Weber, Michael H.; Johnson, Michael G.; Nataraj, Andrew; Attabib, Najmedden; Kelly, Adrienne; Hall, Hamilton; Rampersaud, Y. Raja; Manson, Neil; Phan, Philippe; Thomas, Ken; Fisher, Charles; Charest-Morin, Raphaele; Soroceanu, Alex; LaRue, Bernard; Dea, Nicolas 分享 收藏
Outcome of spine surgery in patients with depressed mental states: a Canadian spine outcome research network study Cushnie, Duncan; Soroceanu, Alex; Stratton, Alexandra; Dea, Nicolas; Finkelstein, Joel; Bailey, Christopher S.; Weber, Michael H.; Paquet, Jerome; Glennie, Andrew; Hall, Hamilton; Rampersaud, Raja; Ahn, Henry; Kelly, Adrienne; Christie, Sean; Nataraj, Andrew; Johnson, Michael; Abraham, Ed; Attabib, Najmedden; Fisher, Charles; Manson, Neil; Thomas, Kenneth 分享 收藏
Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy Wang, Shuaijin; Hebert, Jeffrey J.; Abraham, Edward; Vandewint, Amanda; Bigney, Erin; Richardson, Eden; El-Mughayyar, Dana; Attabib, Najmedden; Wedderkopp, Niels; Kingwell, Stephen; Soroceanu, Alex; Weber, M. H.; Hall, Hamilton; Finkelstein, Joel; Bailey, Christopher S.; Thomas, Kenneth; Nataraj, Andrew; Paquet, Jerome; Johnson, Michael G.; Fisher, Charles; Rampersaud, Y. Raja; Dea, Nicolas; Small, Chris; Manson, Neil 分享 收藏
Fulfillment of Patient Expectations After Spine Surgery is Critical to Patient Satisfaction: A Cohort Study of Spine Surgery Patients 脊柱手术后患者期望的满足对患者满意度至关重要: 一项脊柱手术患者的队列研究 Rampersaud, Y. Raja; Canizares, Mayilee; Perruccio, Anthony V.; Abraham, Edward; Bailey, Christopher S.; Christie, Sean D.; Evaniew, Nathan; Finkelstein, Joel A.; Glennie, Raymond Andrew; Johnson, Michael G.; Nataraj, Andrew; Paquet, Jerome; Phan, Philippe; Weber, Michael H.; Thomas, Kenneth; Manson, Neil; Hall, Hamilton; Fisher, Charles G. 分享 收藏
Differentiation of pain-related functional limitations in surgical patients with lumbar spinal stenosis (LSS) using the Oswestry Disability Index: a Canadian Spine Outcomes and Research Network (CSORN) study Charalampidis, Anastasios; Canizares, Mayilee; Kalsi, Pratipal S.; Wu, Pang Hung; Johnson, Michael; Soroceanu, Alex; Nataraj, Andrew; Glennie, Andrew; Rasoulinejad, Parham; Attabib, Najmedden; Hall, Hamilton; Fisher, Charles; Thomas, Kenneth; Rampersaud, Yoga Raja 分享 收藏
The Effect of Perioperative Adverse Events on Long-Term Patient-Reported Outcomes After Lumbar Spine Surgery Ayling, Oliver G. S.; Ailon, Tamir; Street, John T.; Dea, Nicolas; McIntosh, Greg; Abraham, Edward; Jacobs, W. Bradly; Soroceanu, Alex; Johnson, Michael G.; Paquet, Jerome; Rasoulinejad, Parham; Phan, Phillipe; Yee, Albert; Christie, Sean; Nataraj, Andrew; Glennie, R. Andrew; Hall, Hamilton; Manson, Neil; Rampersaud, Y. Raja; Thomas, Kenneth; Fisher, Charles G. 分享 收藏
Effectiveness of Surgical Decompression in Patients With Degenerative Cervical Myelopathy: Results of the Canadian Prospective Multicenter Study 退行性脊髓型颈椎病患者手术减压的有效性: 加拿大前瞻性多中心研究的结果 Karim, S. Mohammed; Cadotte, David W.; Wilson, Jefferson R.; Kwon, Brian K.; Jacobs, W. Bradley; Johnson, Michael G.; Paquet, Jerome; Bailey, Christopher S.; Christie, Sean D.; Nataraj, Andrew; Attabib, Najmedden; Phan, Philippe; McIntosh, Greg; Hall, Hamilton; Rampersaud, Y. Raja; Manson, Neil; Thomas, Kenneth C.; Fisher, Charles G.; Dea, Nicolas 分享 收藏
Mental health improvements after elective spine surgery: a Canadian Spine Outcome Research Network (CSORN) study Cushnie, D.; Fisher, C.; Hall, H.; Johnson, M.; Christie, S.; Bailey, C.; Phan, P.; Abraham, E.; Glennie, A.; Jacobs, B.; Paquet, J.; Thomas, K. 分享 收藏
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking Schuller, Marion; Correy, Galen J.; Gahbauer, Stefan; Fearon, Daren; Wu, Taiasean; Diaz, Roberto Efrain; Young, Iris D.; Martins, Luan Carvalho; Smith, Dominique H.; Schulze-Gahmen, Ursula; Owens, Tristan W.; Deshpande, Ishan; Merz, Gregory E.; Thwin, Aye C.; Biel, Justin T.; Peters, Jessica K.; Moritz, Michelle; Herrera, Nadia; Kratochvil, Huong T.; Aimon, Anthony; Bennett, James M.; Neto, Jose Brandao; Cohen, Aina E.; Dias, Alexandre; Douangamath, Alice; Dunnett, Louise; Fedorov, Oleg; Ferla, Matteo P.; Fuchs, Martin R.; Gorrie-Stone, Tyler J.; Holton, James M.; Johnson, Michael G.; Krojer, Tobias; Meig, George; Powell, Ailsa J.; Rack, Johannes Gregor Matthias; Rangel, Victor L.; Russi, Silvia; Skyner, Rachael E.; Smith, Clyde A.; Soares, Alexei S.; Wierman, Jennifer L.; Zhu, Kang; O'Brien, Peter; Jura, Natalia; Ashworth, Alan; Irwin, John J.; Thompson, Michael C.; Gestwicki, Jason E.; von Delft, Frank; Shoichet, Brian K.; Fraser, James S.; Ahel, Ivan 分享 收藏
The Effect of Perioperative Adverse Events on Long-Term Patient-Reported Outcomes After Lumbar Spine Surgery 围手术期不良事件对腰椎术后患者长期报告结果的影响 Ayling, Oliver G. S.; Ailon, Tamir; Street, John T.; Dea, Nicolas; McIntosh, Greg; Abraham, Edward; Jacobs, W. Bradly; Soroceanu, Alex; Johnson, Michael G.; Paquet, Jerome; Rasoulinejad, Parham; Phan, Phillipe; Yee, Albert; Christie, Sean; Nataraj, Andrew; Glennie, R. Andrew; Hall, Hamilton; Manson, Neil; Rampersaud, Y. Raja; Thomas, Kenneth; Fisher, Charles G. 分享 收藏
Back pain in surgically treated degenerative lumbar spondylolisthesis: what can we tell our patients? 退行性腰椎滑脱手术治疗的背痛: 我们能告诉我们的病人什么? Bond, Michael; Evaniew, Nathan; Bailey, Christopher S.; Glennie, Raymond Andrew; Paquet, Jerome; Dea, Nicolas; Hall, Hamilton; Manson, Neil; Thomas, Ken; McIntosh, Greg; Soroceanu, Alex; Abraham, Edward; Johnson, Michael; Kingwell, Stephen; Charest-Morin, Raphaele; Christie, Sean; Rampersaud, Y. Raja; Fisher, Charles G. 分享 收藏
Patients' expectations of spine surgery for degenerative conditions: results from the Canadian Spine Outcomes and Research Network (CSORN) 患者对脊柱退行性疾病的期望: 来自加拿大脊柱结果和研究网络 (CSORN) 的结果 Canizares, Mayilee; Gleenie, Raymond Andrew; Perruccio, Anthony, V; Abraham, Edward; Ahn, Henry; Attabib, Najmedden; Christie, Sean; Johnson, Michael G.; Nataraj, Andrew; Nicholls, Fred; Paquet, Jerome; Phan, Phillipe; Rasoulinejad, Parham; Manson, Neil; Hall, Hamilton; Thomas, Kenneth; Fisher, Charles G.; Rampersaud, Y. Raja 分享 收藏
Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2 Pettus, Liping H.; Bourbeau, Matthew P.; Bradley, Jodi; Bartberger, Michael D.; Chen, Kui; Hickman, Dean; Johnson, Michael; Liu, Qingyian; Manning, James R.; Nanez, Adrian; Siegmund, Aaron C.; Wen, Paul H.; Whittington, Douglas A.; Allen, Jennifer R.; Wood, Stephen 分享 收藏