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Dupilumab Demonstrates Rapid Onset of Response Across Three Type 2 Inflammatory Diseases Canonica, G. Walter; Bourdin, Arnaud; Peters, Anju T.; Desrosiers, Martin; Bachert, Claus; Weidinger, Stephan; Simpson, Eric L.; Daizadeh, Nadia; Chen, Zhen; Kamat, Siddhesh; Khan, Asif H.; Chao, Jingdong; Graham, Neil M. H.; Laws, Elizabeth; Rossi, Ana B.; Ardeleanu, Marius; Mannent, Leda P.; Amin, Nikhil; Ortiz, Benjamin; Deniz, Yamo; Djandji, Michel; Rowe, Paul J. 分享 收藏
Olfactory Outcomes With Dupilumab in Chronic Rhinosinusitis With Nasal Polyps Dupilumab在慢性鼻鼻窦炎伴鼻息肉中的嗅觉结果 Mullol, Joaquim; Bachert, Claus; Amin, Nikhil; Desrosiers, Martin; Hellings, Peter W.; Han, Joseph K.; Jankowski, Roger; Vodicka, Jan; Gevaert, Philippe; Daizadeh, Nadia; Khan, Asif H.; Kamat, Siddhesh; Patel, Naimish; Graham, Neil M. H.; Ruddy, Marcella; Staudinger, Heribert; Mannent, Leda P. 分享 收藏
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations in patients with uncontrolled, moderate-to-severe asthma receiving placebo in the LIBERTY ASTHMA QUEST study: a post-hoc analysis 在LIBERTY哮喘QUEST研究中，基线FeNO作为接受安慰剂的未控制，中至重度哮喘患者随后重度哮喘发作的预后生物标志物: 事后分析 Busse, William W.; Wenzel, Sally E.; Casale, Thomas B.; FitzGerald, J. Mark; Rice, Megan S.; Daizadeh, Nadia; Deniz, Yamo; Patel, Naimish; Harel, Sivan; Rowe, Paul J.; Graham, Neil M. H.; O'Riordan, Thomas; Pavord, Ian D. 分享 收藏
Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases Hamilton, Jennifer D.; Harel, Sivan; Swanson, Brian N.; Brian, William; Chen, Zhen; Rice, Megan S.; Amin, Nikhil; Ardeleanu, Marius; Radin, Allen; Shumel, Brad; Ruddy, Marcella; Patel, Naimish; Pirozzi, Gianluca; Mannent, Leda; Graham, Neil M. H. 分享 收藏
Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST Dupilumab对未控制的中至重度哮喘青少年的疗效: LIBERTY哮喘的探索 Maspero, Jorge F.; FitzGerald, John Mark; Pavord, Ian D.; Rice, Megan S.; Maroni, Jaman; Rowe, Paul J.; Pirozzi, Gianluca; Amin, Nikhil; Ruddy, Marcella; Graham, Neil M. H.; Teper, Ariel; Hardin, Megan 分享 收藏
Dupilumab Improves Asthma and Sinonasal Outcomes in Adults with Moderate to Severe Atopic Dermatitis Dupilumab可改善中度至重度特应性皮炎成人的哮喘和鼻窦结局 Boguniewicz, Mark; Beck, Lisa A.; Sher, Lawrence; Guttman-Yassky, Emma; Thaci, Diamant; Blauvelt, Andrew; Worm, Margitta; Corren, Jonathan; Soong, Weily; Lio, Peter; Rossi, Ana B.; Lu, Yufang; Chao, Jingdong; Eckert, Laurent; Gadkari, Abhijit; Hultsch, Thomas; Ruddy, Marcella; Mannent, Leda P.; Graham, Neil M. H.; Pirozzi, Gianluca; Chen, Zhen; Ardeleanu, Marius 分享 收藏
Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma Bansal, Ashish; Simpson, Eric L.; Paller, Amy S.; Siegfried, Elaine C.; Blauvelt, Andrew; de Bruin-Weller, Marjolein; Corren, Jonathan; Sher, Lawrence; Guttman-Yassky, Emma; Chen, Zhen; Daizadeh, Nadia; Kamal, Mohamed A.; Shumel, Brad; Mina-Osorio, Paola; Mannent, Leda; Patel, Naimish; Graham, Neil M. H.; Khokhar, Faisal A.; Ardeleanu, Marius 分享 收藏
Dupilumab Efficacy in Patients Stratified by Baseline Treatment Intensity and Lung Function Pavord, Ian D.; Siddiqui, Salman; Papi, Alberto; Corren, Jonathan; Sher, Lawrence D.; Bardin, Philip; Langton, David; Park, Hae-Sim; Rice, Megan S.; Deniz, Yamo; Rowe, Paul; Staudinger, Heribert W.; Patel, Naimish; Ruddy, Marcella; Graham, Neil M. H.; Teper, Ariel 分享 收藏
A phase 2, open-label study of single-dose dupilumab in children aged 6 months to <6 years with severe uncontrolled atopic dermatitis: pharmacokinetics, safety and efficacy Paller, A. S.; Siegfried, E. C.; Simpson, E. L.; Cork, M. J.; Lockshin, B.; Kosloski, M. P.; Kamal, M. A.; Davis, J. D.; Sun, X.; Pirozzi, G.; Graham, N. M. H.; Gadkari, A.; Eckert, L.; Ruddy, M.; Bansal, A. 分享 收藏
Dupilumab Significantly Modulates Pain and Discomfort in Patients With Atopic Dermatitis: A Post Hoc Analysis of 5 Randomized Clinical Trials Silverberg, Jonathan, I; Simpson, Eric L.; Guttman-Yassky, Emma; Cork, Michael J.; de Bruin-Weller, Marjolein; Yosipovitch, Gil; Eckert, Laurent; Chen, Zhen; Ardeleanu, Marius; Shumel, Brad; Hultsch, Thomas; Rossi, Ana B.; Hamilton, Jennifer D.; Orengo, Jamie M.; Ruddy, Marcella; Graham, Neil M. H.; Pirozzi, Gianluca; Gadkari, Abhijit 分享 收藏
Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-controlled phase 3 trial Paller, Amy S.; Siegfried, Elaine C.; Thaci, Diamant; Wollenberg, Andreas; Cork, Michael J.; Arkwright, Peter D.; Gooderham, Melinda; Beck, Lisa A.; Boguniewicz, Mark; Sher, Lawrence; Weisman, Jamie; O'Malley, John T.; Patel, Naimish; Hardin, Megan; Graham, Neil M. H.; Ruddy, Marcella; Sun, Xian; Davis, John D.; Kamal, Mohamed A.; Khokhar, Faisal A.; Weinreich, David M.; Yancopoulos, George D.; Beazley, Bethany; Bansal, Ashish; Shumel, Brad 分享 收藏
Dupilumab provides favourable long-term safety and efficacy in children aged ≥ 6 to < 12 years with uncontrolled severe atopic dermatitis: results from an open-label phase IIa study and subsequent phase III open-label extension study Cork, M. J.; Thaci, D.; Eichenfield, L. F.; Arkwright, P. D.; Sun, X.; Chen, Z.; Akinlade, B.; Boklage, S.; Guillemin, I.; Kosloski, M. P.; Kamal, M. A.; O'Malley, J. T.; Patel, N.; Graham, N. M. H.; Bansal, A. 分享 收藏
Dupilumab significantly improves sleep outcomes in adult patients with atopic dermatitis: results from five randomized clinical trials Beck, L. A.; Silverberg, J. I.; Simpson, E. L.; Yosipovitch, G.; Eckert, L.; Guillemin, I.; Chen, Z.; Ardeleanu, M.; Plaum, S.; Graham, N.; Ruddy, M.; Pirozzi, G.; Gadkari, A. 分享 收藏
Association of High Serum Interleukin-6 Levels With Severe Progression of Rheumatoid Arthritis and Increased Treatment Response Differentiating Sarilumab From Adalimumab or Methotrexate in a Post Hoc Analysis Boyapati, Anita; Schwartzman, Sergio; Msihid, Jerome; Choy, Ernest; Genovese, Mark C.; Burmester, Gerd R.; Lam, Gordon; Kimura, Toshio; Sadeh, Jonathan; Weinreich, David M.; Yancopoulos, George D.; Graham, Neil M. H. 分享 收藏
Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis Beck, Lisa A.; Thaci, Diamant; Deleuran, Mette; Blauvelt, Andrew; Bissonnette, Robert; de Bruin-Weller, Marjolein; Hide, Michihiro; Sher, Lawrence; Hussain, Iftikhar; Chen, Zhen; Khokhar, Faisal A.; Beazley, Bethany; Ruddy, Marcella; Patel, Naimish; Graham, Neil M. H.; Ardeleanu, Marius; Shumel, Brad 分享 收藏
Dupilumab treatment results in early and sustained improvements in itch in adolescents and adults with moderate to severe atopic dermatitis: Analysis of the randomized phase 3 studies SOLO 1 and SOLO 2, AD ADOL, and CHRONOS Silverberg, Jonathan I.; Yosipovitch, Gil; Simpson, Eric L.; Kim, Brian S.; Wu, Jashin J.; Eckert, Laurent; Guillemin, Isabelle; Chen, Zhen; Ardeleanu, Marius; Bansal, Ashish; Kaur, Mandeep; Rossi, Ana B.; Graham, Neil M. H.; Patel, Naimish; Gadkari, Abhijit 分享 收藏
Laboratory safety of dupilumab in moderate-to-severe atopic dermatitis: results from three phase III trials (LIBERTY AD SOLO 1, LIBERTY AD SOLO 2, LIBERTY AD CHRONOS) Wollenberg, A.; Beck, L. A.; Blauvelt, A.; Simpson, E. L.; Chen, Z.; Chen, Q.; Shumel, B.; Khokhar, F. A.; Hultsch, T.; Rizova, E.; Rossi, A. B.; Graham, N. M. H.; Pirozzi, G.; Lu, Y.; Ardeleanu, M. 分享 收藏
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Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma Dupilumab在未控制的中至重度过敏性哮喘患者中的疗效 Corren, Jonathan; Castro, Mario; O'Riordan, Thomas; Hanania, Nicola A.; Pavord, Ian D.; Quirce, Santiago; Chipps, Bradley E.; Wenzel, Sally E.; Thangavelu, Karthinathan; Rice, Megan S.; Harel, Sivan; Jagerschmidt, Alexandre; Khan, Asif H.; Kamat, Siddhesh; Maroni, Jaman; Rowe, Paul; Lu, Yufang; Amin, Nikhil; Pirozzi, Gianluca; Ruddy, Marcella; Graham, Neil M. H.; Teper, Ariel 分享 收藏
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