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收藏Novel dual action chimera doxorubizen demonstrates superior efficacy to doxorubicin in acute leukemia
Walunj, Dipak; Egarmina, Katarina; Zipin-Roitman, Adi; Muddineni, Siva Sai Naga Anurag; Tkachenko, Iryna; Mitra, Pousali; Tobi, Dror; Bazylevich, Andrii; Shpilberg, Ofer; Milyavsky, Michael; Hershkovitz-Rokah, Oshrat; Gellerman, Gary 分享 收藏 分享 收藏 The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERGKugler, Eitan; Madiwale, Shreyas; Yong, Darren; Thoms, Julie A. I.; Birger, Yehudit; Sykes, David B.; Schmoellerl, Johannes; Drakul, Aneta; Priebe, Valdemar; Yassin, Muhammad; Aqaqe, Nasma; Rein, Avigail; Fishman, Hila; Geron, Ifat; Chen, Chun-Wei; Raught, Brian; Liu, Qiao; Ogana, Heather; Liedke, Elisabeth; Bourquin, Jean-Pierre; Zuber, Johannes; Milyavsky, Michael; Pimanda, John; Prive, Gilbert G.; Izraeli, Shai 分享 收藏 分享 收藏 KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibitionBoila, Liberalis Debraj; Ghosh, Subhadeep; Bandyopadhyay, Subham K.; Jin, Liqing; Murison, Alex; Zeng, Andy G. X.; Shaikh, Wasim; Bhowmik, Satyaki; Muddineni, Siva Sai Naga Anurag; Biswas, Mayukh; Sinha, Sayantani; Chatterjee, Shankha Subhra; Mbong, Nathan; Gan, Olga I.; Bose, Anwesha; Chakraborty, Sayan; Arruda, Andrea; Kennedy, James A.; Mitchell, Amanda; Lechman, Eric R.; Banerjee, Debasis; Milyavsky, Michael; Minden, Mark D.; Dick, John E.; Sengupta, Amitava 分享 收藏 Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joiningFeldman, Tzah; Bercovich, Akhiad; Moskovitz, Yoni; Chapal-Ilani, Noa; Mitchell, Amanda; Medeiros, Jessie J. F.; Biezuner, Tamir; Kaushansky, Nathali; Minden, Mark D.; Gupta, Vikas; Milyavsky, Michael; Livneh, Zvi; Tanay, Amos; Shlush, Liran I. 分享 收藏 The mTOR inhibitor everolimus overcomes CXCR4-mediated resistance to histone deacetylase inhibitor panobinostat through inhibition of p21 and mitotic regulatorsBeider, Katia; Bitner, Hanna; Voevoda-Dimenshtein, Valeria; Rosenberg, Evgenia; Sirovsky, Yaarit; Magen, Hila; Canaani, Jonathan; Ostrovsky, Olga; Shilo, Noya; Shimoni, Avichai; Abraham, Michal; Weiss, Lola; Milyavsky, Michael; Peled, Amnon; Nagler, Arnon 分享 收藏 An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward RegulationAqaqe, Nasma; Yassin, Muhammad; Yassin, Abed Alkader; Ershaid, Nour; Katz-Even, Chen; Zipin-Roitman, Adi; Kugler, Eitan; Lechman, Eric R.; Gan, Olga I.; Mitchell, Amanda; Dick, John E.; Izraeli, Shai; Milyavsky, Michael 分享 收藏 A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivityYassin, Muhammad; Aqaqe, Nasma; Yassin, Abed Alkader; van Galen, Peter; Kugler, Eitan; Bernstein, Bradley E.; Koren-Michowitz, Maya; Canaani, Jonathan; Nagler, Arnon; Lechman, Eric R.; Dick, John E.; Wienholds, Erno; Izraeli, Shai; Milyaysky, Michael 分享 收藏 Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage responseGold, Ayala; Eini, Lital; Nissim-Rafinia, Malka; Viner, Ruth; Ezer, Shlomit; Erez, Keren; Aqaqe, Nasma; Hanania, Rotem; Milyavsky, Michael; Meshorer, Eran; Goldberg, Michal 分享 收藏 Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancerRaz, Yael; Cohen, Noam; Shani, Ophir; Bell, Rachel E.; Novitskiy, Sergey V.; Abramovitz, Lilach; Levy, Carmit; Milyavsky, Michael; Leider-Trejo, Leonor; Moses, Harold L.; Grisaru, Dan; Erez, Neta 分享 收藏 Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastomaTiram, Galia; Ferber, Shiran; Ofek, Paula; Eldar-Boock, Anat; Ben-Shushan, Dikla; Yeini, Eilam; Krivitsky, Adva; Blatt, Roni; Almog, Nava; Henkin, Jack; Amsalem, Orit; Yavin, Eylon; Cohen, Gadi; Lazarovici, Philip; Lee, Joo Sang; Ruppin, Eytan; Milyavsky, Michael; Grossman, Rachel; Ram, Zvi; Calderon, Marcelo; Haag, Rainer; Satchi-Fainaro, Ronit 分享 收藏 Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiationBiechonski, Shahar; Olender, Leonid; Zipin-Roitman, Adi; Yassin, Muhammad; Aqaqe, Nasma; Marcu-Malina, Victoria; Rall-Scharpf, Melanie; Trottier, Magan; Meyn, M. Stephen; Wiesmueller, Lisa; Beider, Katia; Raz, Yael; Grisaru, Dan; Nagler, Arnon; Milyavsky, Michael 分享 收藏 分享 收藏 Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangementsBiechonski, Shahar; Gourevich, Dana; Rall, Melanie; Aqaqe, Nasma; Yassin, Muhammad; Zipin-Roitman, Adi; Trakhtenbrot, Luba; Olender, Leonid; Raz, Yael; Jaffa, Ariel J.; Grisaru, Dan; Wiesmuller, Lisa; Elad, David; Milyavsky, Michael 分享 收藏 分享 收藏 Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signalingLnk适配器通过抑制IL-11信号抑制辐射抗性和辐射诱导的b细胞恶性肿瘤Louria-Hayon, Igal; Frelin, Catherine; Ruston, Julie; Gish, Gerald; Jin, Jing; Kofler, Michael M.; Lambert, Jean-Philippe; Adissu, Hibret A.; Milyavsky, Michael; Herrington, Robert; Minden, Mark D.; Dick, John E.; Gingras, Anne-Claude; Iscove, Norman N.; Pawson, Tony 分享 收藏 分享 收藏 分享 收藏 
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