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收藏MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density
Papin, Christophe; Ibrahim, Abdulkhaleg; Sabir, Jamal S. M.; Le Gras, Stephanie; Stoll, Isabelle; Albiheyri, Raed S.; Zari, Ali T.; Bahieldin, Ahmed; Bellacosa, Alfonso; Bronner, Christian; Hamiche, Ali
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收藏TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator PhenotypeTET1和TDG抑制肠道肿瘤发生中的炎症反应: 对具有CpG岛甲基化表型的结直肠肿瘤的影响
Tricarico, Rossella; Madzo, Jozef; Scher, Gabrielle; Cohen, Maya; Jelinek, Jaroslav; Maegawa, Shinji; Nagarathinam, Rajeswari; Scher, Carly; Chang, Wen-Chi; Nicolas, Emmanuelle; Slifker, Michael; Zhou, Yan; Devarajan, Karthik; Cai, Kathy Q.; Kwok, Tim; Nakajima, Pamela; Xu, Jinfei; Mancuso, Pietro; Doneddu, Valentina; Bagella, Luigi; Williams, Riley; Balachandran, Siddharth; Maskalenko, Nicholas; Campbell, Kerry; Ma, Xueying; Canadas, Israel; Viana-Errasti, Julen; Moreno, Victor; Valle, Laura; Grivennikov, Sergei; Peshkova, Iuliia; Kurilenko, Natalia; Mazitova, Aleksandra; Koltsova, Ekaterina; Lee, Hayan; Walsh, Martin; Duttweiler, Reuben; Whetstine, Johnathan R.; Yen, Timothy J.; Issa, Jean-Pierre; Bellacosa, Alfonso
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收藏Nuclear Expression of β-Catenin Is Associated with Improved Outcomes in Endometrial Cancer
Masciullo, Valeria; Susini, Tommaso; Corrado, Giacomo; Stepanova, Marina; Baroni, Alessandro; Renda, Irene; Castiglione, Francesca; Minimo, Corrado; Bellacosa, Alfonso; Chiofalo, Benito; Vizza, Enrico; Scambia, Giovanni
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收藏The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells药物外排泵MDR1促进癌细胞对PROTACs的内在和获得性耐药
Kurimchak, Alison M.; Herrera-Montavez, Carlos; Montserrat-Sangra, Sara; Araiza-Olivera, Daniela; Hu, Jianping; Neumann-Domer, Ryan; Kuruvilla, Mathew; Bellacosa, Alfonso; Testa, Joseph R.; Jin, Jian; Duncan, James S.
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收藏Thymine DNA glycosylase as a novel target for melanoma (vol 38, pg 3710, 2019)
Mancuso, Pietro; Tricarico, Rossella; Bhattacharjee, Vikram; Cosentino, Laura; Kadariya, Yuwaraj; Jelinek, Jaroslav; Nicolas, Emmanuelle; Einarson, Margret; Beeharry, Neil; Devarajan, Karthik; Katz, Richard A.; Dorjsuren, Dorjbal G.; Sun, Hongmao; Simeonov, Anton; Giordano, Antonio; Testa, Joseph R.; Davidson, Guillaume; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy J.; Bellacosa, Alfonso
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收藏BRN2 is a non-canonical melanoma tumor-suppressor
Hamm, Michael; Sohier, Pierre; Petit, Valerie; Raymond, Jeremy H.; Delmas, Veronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrimsson, Eirikur; Jonsson, Goran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel
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收藏NeuroD1 Dictates Tumor Cell Differentiation in MedulloblastomaNeuroD1决定了髓母细胞瘤的肿瘤细胞分化
Cheng, Yan; Liao, Shengyou; Xu, Gang; Hu, Jian; Guo, Duancheng; Du, Fang; Contreras, Alejandra; Cai, Kathy Q.; Peri, Suraj; Wang, Yuan; Corney, David C.; Noronha, Anne Marie; Chau, Lianne Q.; Zhou, Ginger; Wiest, David L.; Bellacosa, Alfonso; Wechsler-Reya, Robert J.; Zhao, Yi; Yang, Zeng-jie
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收藏Modification of the base excision repair enzyme MBD4 by the small ubiquitin-like molecule SUMO1
Sannai, Mara; Doneddu, Valentina; Giri, Veda; Seeholzer, Steven; Nicolas, Emmanuelle; Yip, Shu-Chin; Bassi, Maria Rosaria; Mancuso, Pietro; Cortellino, Salvatore; Cigliano, Antonio; Lurie, Rebecca; Ding, Hua; Chernoff, Jonathan; Sobol, Robert W.; Yen, Timothy J.; Bagella, Luigi; Bellacosa, Alfonso
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收藏Thymine DNA glycosylase as a novel target for melanoma
Mancuso, Pietro; Tricarico, Rossella; Bhattacharjee, Vikram; Cosentino, Laura; Kadariya, Yuwaraj; Jelinek, Jaroslav; Nicolas, Emmanuelle; Einarson, Margret; Beeharry, Neil; Devarajan, Karthik; Katz, Richard A.; Dorjsuren, Dorjbal G.; Sun, Hongmao; Simeonov, Anton; Giordano, Antonio; Testa, Joseph R.; Davidson, Guillaume; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy J.; Bellacosa, Alfonso
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收藏BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance (vol 24, 3513, 2018)
Nacson, Joseph; Krais, John J.; Bernhardy, Andrea J.; Clausen, Emma; Feng, Wanjuan; Wang, Yifan; Nicolas, Emmanuelle; Cai, Kathy Q.; Tricarico, Rossella; Hua, Xiang; DiMarcantonio, Daniela; Martinez, Esteban; Zong, Dali; Handorf, Elizabeth A.; Bellacosa, Alfonso; Testa, Joseph R.; Nussenzweig, Andre; Gupta, Gaorav P.; Sykes, Stephen M.; Johnson, Neil
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收藏BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
Nacson, Joseph; Krais, John J.; Bernhardy, Andrea J.; Clausen, Emma; Feng, Wanjuan; Wang, Yifan; Nicolas, Emmanuelle; Cai, Kathy Q.; Tricarico, Rossella; Hua, Xiang; DiMarcantonio, Daniela; Martinez, Esteban; Zong, Dali; Handorf, Elizabeth A.; Bellacosa, Alfonso; Testa, Joseph R.; Nussenzweig, Andre; Gupta, Gaorav P.; Sykes, Stephen M.; Johnson, Neil
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收藏Thymine DNA glycosylase (TDG) as a novel target for melanoma
Tricarico, Rossella; Mancuso, Pietro; Bhattacharjee, Vikram; Cosentino, Laura; Nicolas, Emmanuelle; Einarson, Margret; Beeharry, Neil; Devarajan, Karthik; Katz, Rich; Dorjsuren, Dorjbal G.; Simeonov, Anton; Kadariya, Yuwaraj; Davidson, Guillaume; Testa, Joseph R.; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy; Bellacosa, Alfonso
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收藏An Intrinsic Epigenetic Barrier for Functional Axon Regeneration
Weng, Yi-Lan; An, Ran; Cassin, Jessica; Joseph, Jessica; Mi, Ruifa; Wang, Chen; Zhong, Chun; Jin, Seung-Gi; Pfeifer, Gerd P.; Bellacosa, Alfonso; Dong, Xinzhong; Hoke, Ahmet; He, Zhigang; Song, Hongjun; Ming, Guo-li
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收藏A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activityPTEN在 β-连环蛋白转录活性中的小窝蛋白依赖性和PI3K/AKT非依赖性作用
Conde-Perez, Alejandro; Gros, Gwendoline; Longvert, Christine; Pedersen, Malin; Petit, Valerie; Aktary, Zackie; Viros, Amaya; Gesbert, Franck; Delmas, Veronique; Rambow, Florian; Bastian, Boris C.; Campbell, Andrew D.; Colombo, Sophie; Puig, Isabel; Bellacosa, Alfonso; Sansom, Owen; Marais, Richard; Van Kempen, Leon C. L. T.; Larue, Lionel
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收藏TDG, a dual genomic and epigenomic regulator, as a novel antimelanoma target
Tricarico, Rossella; Mancuso, Pietro; Bhattacharjee, Vikram; Beeharry, Neil; Nicolas, Emmanuelle; Einarson, Margret; Cosentino, Laura; Davidson, Irwin; Larue, Lionel; Sobol, Robert W.; Yen, Timothy J.; Bellacosa, Alfonso
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