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The single cell landscape of NF1-associated gliomas pre- and post-treatment and comparison to their sporadic counterparts NF1相关胶质瘤治疗前后单细胞景观及其与散发型对照的比较 Gupta, Rohit; Ravindranathan, Ajay; Wu, Jasper; Lucas, Calixto-Hope; Shai, Anny; Nazarian, Javad; Campen, Cynthia; Partap, Sonia; Omuro, Antonio; Gephart, Melanie Hayden; Lim, Michael; Butowski, Nicholas; Berger, Mitchel; Reddy, Alyssa; Phillips, Joanna; Solomon, David 分享 收藏
UPDATED RESULTS OF PHASE 3 STELLAR TRIAL: EFLORNITHINE IMPROVES OVERALL SURVIVAL AND BLINDED INDEPENDENT CENTRAL REVIEW DETERMINED PROGRESSION FREE SURVIVAL IN PATIENTS WITH RECURRENT WHO 2021 GRADE 3 IDH-MUTANT ASTROCYTOMA 更新后的III期STELLAR试验结果：依氟鸟氨酸改善2021年WHO分级3级IDH突变型星形细胞瘤患者的总生存期和盲态独立中央审查确定的无进展生存期 Colman, Howard; Lombardi, Giuseppe; Wong, Eric; Walbert, Tobias; Eoli, Marica; Lassman, Andrew; Peereboom, David; Kizilbash, Sani; Kamiya-Matsuoka, Carlos; Pitz, Marshall; Strowd, Roy; Desjardins, Annick; Kumthekar, Priya; Mason, Warren; Pellerino, Alessia; Soffietti, Riccardo; Butowski, Nicholas; Forsyth, Peter; Hamza, Mohamed; Hau, Peter; Lallana, Enrico; Nabors, Burt; Piccioni, David; Uhlmann, Erik; Welsh, Liam; Wen, Patrick; Dietrich, Jorg; Levin, Victor 分享 收藏
Safety, feasibility, and preliminary efficacy of albumin-bound paclitaxel as monotherapy and in combination with carboplatin delivered by blood-brain barrier opening using a skull-implantable ultrasound: Preliminary results of a Phase I-II trial in recurrent glioblastoma 安全性、可行性和白蛋白结合型紫杉醇作为单药治疗及与卡铂联合治疗，通过颅骨植入式超声打开血脑屏障进行递送的临床初步疗效：一项针对复发性胶质母细胞瘤的I-II期临床试验的初步结果 Sonabend, Adam M.; Lukas, Rimas, V; Dixit, Karan; Kumthekar, Priya; Primdahl, Ditte; Tate, Matthew; Chandler, James; Magill, Stephen; Torres, Elena; Vandermolen, Sarah; Ward, Rachel; Nieves, Mariana; Pituch, Katarzyna; Bebawy, John; Zhang, Hui; Bazzi, Latifa; Habashy, Karl; Hervey-Jumper, Shawn; Butowski, Nicholas; Berger, Mitchell; Bouchoux, Guillaume; Canney, Michael; Desseaux, Carole; Carpentier, Alexandre; Stupp, Roger 分享 收藏
Trial in progress update: A phase 1/2 study of intracranial and intravenous multi-dosing of DB107-RRV (formerly Toca 511) and DB107-FC (5-fluorocytosine) in combination with radiation ± temozolomide (TMZ) in patients with newly diagnosed high-grade gliomas (HGGs) 试验进行中更新：一项关于DB107-RRV（原Toca 511）和DB107-FC（5-氟胞嘧啶）颅内及静脉多剂量给药，并与放疗联合±替莫唑胺（TMZ）治疗新诊断的高级别胶质瘤（HGGs）的1/2期研究。 Reddy, Megna; Kasahara, Noriyuki; Chen, Thomas C.; Piccioni, David E.; Chang, Susan M.; Clarke, Jennifer L.; De Groot, John F.; Na, Brian S.; Nelson, Thomas; Bush, Nancy Ann Oberheim; Taylor, Jennie W.; Beardmore, Chris; Madzarevic, Vera; Walsh, Martin; Young, Jacob S.; Butowski, Nicholas 分享 收藏
SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERE RADIATION THERAPY IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL 钇-90玻璃微球放射治疗复发性胶质母细胞瘤的安全性与可行性：FRONTIER试验中首批12例患者的治疗结果 Stupp, Roger; Ansari, Sameer; Tate, Matthew; Lukas, Rimas; Dixit, Karan; Butowski, Nicholas; Narsinh, Kazim; Boockvar, John; Weinstein, Jonathan; Serulle, Yafell; Middlebrooks, Erik; Trifiletti, Daniel; Basarabescu, Franco; Kennedy, Paul; Eldridge, Amanda; Ryan, Samantha; Dreher, Matthew; Salem, Riad; Mouli, Samdeep 分享 收藏
Tele-Cognitive rehabilitation for adult lower grade glioma: A prospective feasibility study 成人低级别胶质瘤的远程认知康复：一项前瞻性可行性研究 Jamora, Christina Weyer; Brie, Melissa; Bracci, Paige; Smith, Ellen; Luks, Tracy; Phan, Stephanie; Braunstein, Steve; Oberheim-Bush, Nancy Ann; Butowski, Nicholas; Clarke, Jennifer; de Groot, John; Barreiro-Rosado, Jeenn; Almonen, Rand; Chang, Susan; Hervey-Jumper, Shawn; Taylor, Jennie 分享 收藏
Build it and they will come: Cognitive rehabilitation in primary brain tumor 建设好了，他们就会来：原发性脑肿瘤的认知康复 Jamora, Christina Weyer; Brie, Melissa; Bracci, Paige; Smith, Ellen; Luks, Tracy; Oberheim-Bush, Nancy Ann; Butowski, Nicholas; Clarke, Jennifer; de Groot, John; Barreiro-Rosado, Jeenn; Almonen, Rand; Chang, Susan; Hervey-Jumper, Shawn; Van Dyk, Kathleen; Taylor, Jennie 分享 收藏
B TELE-COGNITIVE REHABILITATION FOR ADULT LOWER GRADE GLIOMA: A PROSPECTIVE FEASIBILITY STUDY B 远程认知康复对成人低级别胶质瘤的可行性研究 Jamora, C. Weyer; Brie, M.; Bracci, P.; Smith, E.; Luks, T.; Phan, S.; Braunstein, S.; Oberheim-Bush, N. A.; Butowski, N.; Clarke, J.; de Groot, J.; Barreiro-Rosado, J.; Almonen, R.; Chang, S.; Hervey-Jumper, S.; Taylor, J. W. 分享 收藏
IL6 UNDERLIES MICROENVIRONMENT IMMUNOSUPPRESSION AND RESISTANCE TO THERAPY IN GLIOBLASTOMA IL6 是胶质母细胞瘤微环境免疫抑制和耐药性的基础 Young, J. S.; Cho, N.; Lucas, C. G.; Seo, K.; Najem, H.; Mirchia, K.; Chen, W. C.; Zakimi, N.; Daggubati, V; Casey-Clyde, T.; Nguyen, M. P.; Chen, A.; Phillips, J. J.; Ozawa, T.; Aghi, M. K.; Taylor, J. W.; DeRisi, J. L.; Bhaduri, A.; Heimberger, A.; Berger, M. S.; Butowski, N.; Spitzer, M. H.; Raleigh, D. R. 分享 收藏
SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERES IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL 钇-90玻璃微球在复发性胶质母细胞瘤中的安全性与可行性：来自FRONTIER试验中首批12例患者的结果 Stupp, R.; Ansari, S.; Tate, M.; Butowski, N.; Narsinh, K.; Boockvar, J.; Weinstein, J.; Serulle, Y.; Middlebrooks, E.; Trifiletti, D.; Basarabescu, F.; Kennedy, P.; Eldridge, A.; Boucher, E.; Dreher, M.; Salem, R.; Mouli, S. 分享 收藏
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Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival IDH突变型星形细胞瘤的纵向分析揭示了与生存率低下相关的获得性ras-mapk通路突变 Almaraz, Eduardo Rodriguez; Guerra, Geno A.; Al-Adli, Nadeem N.; Young, Jacob S.; Dada, Abraham; Quintana, Daniel; Taylor, Jennie W.; Bush, Nancy Ann Oberheim; Clarke, Jennifer L.; Butowski, Nicholas A.; de Groot, John; Pekmezci, Melike; Perry, Arie; Bollen, Andrew W.; Scheffler, Aaron W.; Glidden, David, V; Phillips, Joanna J.; Costello, Joseph F.; Chang, Edward F.; Hervey-Jumper, Shawn; Berger, Mitchel S.; Francis, Stephen S.; Chang, Susan M.; Solomon, David A. 分享 收藏
A phase I study of convection-enhanced delivery (CED) of liposomal-irinotecan using real-time magnetic resonance imaging in patients with recurrent high-grade glioma Narsinh, Kazim H.; Kumar, Karishma; Bankiewicz, Krystof; Martin, Alastair J.; Berger, Mitchell; Clarke, Jennifer; Taylor, Jennie; Bush, Nancy Ann Oberheim; Molinaro, Annette M.; Aghi, Manish; Butowski, Nicholas 分享 收藏
Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses Lucas, Calixto-Hope G.; Al-Adli, Nadeem N.; Young, Jacob S.; Gupta, Rohit; Morshed, Ramin A.; Wu, Jasper; Ravindranathan, Ajay; Shai, Anny; Oberheim Bush, Nancy Ann; Taylor, Jennie W.; de Groot, John; Villanueva-Meyer, Javier E.; Pekmezci, Melike; Perry, Arie; Bollen, Andrew W.; Theodosopoulos, Philip, V; Aghi, Manish K.; Chang, Edward F.; Hervey-Jumper, Shawn L.; Raleigh, David R.; Molinaro, Annette M.; Costello, Joseph F.; Diaz, Aaron A.; Clarke, Jennifer L.; Butowski, Nicholas A.; Phillips, Joanna J.; Chang, Susan M.; Berger, Mitchel S.; Solomon, David A. 分享 收藏
A FIRST-IN-HUMAN FEASIBILITY STUDY TO EVALUATE THE SAFETY OF SELECTIVE YTTRIUM-90 ENDOVASCULAR RADIOTHERAPY IN PATIENTS WITH RECURRENT GBM: INTERIM RESULTS FROM THE FRONTIER TRIAL Mouli, Samdeep; Ansari, Sameer; Middlebrooks, Erik; Boockvar, John; Weinstein, Jonathan; Serulle, Yafell; Butowski, Nicholas; Narsinh, Kazim; Kennedy, Paul; Eldridge, Amanda; Basarabescu, Franco; Elahi-Gedwillo, Kianna; Salem, Riad; Stupp, Roger 分享 收藏
CLINICAL OUTCOMES AND PREDICTIVE BIOMARKERS FOR IDH-WILDTYPE GLIOBLASTOMAS DEVELOPING HYPERMUTATION FOLLOWING TEMOZOLOMIDE TREATMENT Young, Jacob; Lucas, Calixto-Hope; Al-Adli, Nadeem; Gupta, Rohit; Morshed, Ramin; Wu, Jasper; Ravindranathan, Ajay; Shai, Anny; Oberheim-Bush, Nancy Ann; Taylor, Jennie; de Groot, John; Villanueva-Meyer, Javier; Pekmezci, Melike; Perry, Arie; Bollen, Andy; Theodosopoulos, Philip; Aghi, Manish; Chang, Edward; Hervey-Jumper, Shawn; Raleigh, David; Diaz, Aaron; Costello, Joseph; Clarke, Jennifer; Butowski, Nicholas; Phillips, Joanna; Chang, Susan; Berger, Mitchel; Solomon, David 分享 收藏
PHASE 3 STELLAR STUDY SHOWS EFLORNITHINE IMPROVES OVERALL SURVIVAL (OS) AND PROGRESSION FREE SURVIVAL (PFS) IN PATIENTS WITH RECURRENT 2021 WHO ASTROCYTOMA, IDH-MUTANT GRADE 3 Colman, Howard; Lombardi, Giuseppe; Wong, Eric; Walbert, Tobias; Eoli, Marica; Lassman, Andrew; Peereboom, David; Kizilbash, Sani; Kamiya-Matsuoka, Carlos; Pitz, Marshall; Strowd, Roy; Desjardins, Annick; Kumthekar, Priya; Mason, Warren; Pellerino, Alessia; Soffietti, Ricardo; Butowski, Nicholas; Forsyth, Peter; Hamza, Mohamed; Hau, Peter; Lallana, Enrico; Nabors, Burt; Piccioni, David; Uhlmann, Erik; Welsh, Liam; Wen, Patrick; Dietrich, Jorg; Levin, Victor 分享 收藏
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