Sebastian Kügler - Publications, H-index & Citations

Sebastian Kügler

University of Gottingen

57H指数

158论文数

1.2W被引数

收录论文 55

发表时间

Axonal autophagic vesicle transport in the rat optic nerve in vivo under normal conditions and during acute axonal degeneration

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-05-29

OAAI

Luo, Xiaoyue; Zhang, Jiong; Toloe, Johan; Kuegler, Sebastian; Michel, Uwe; Baehr, Mathias; Koch, Jan Christoph

Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-03-01

OAAI

Knauer, Carolin; Haltern, Henrike; Schoger, Eric; Kuegler, Sebastian; Roos, Lennart; Zelarayan, Laura C.; Hasenfuss, Gerd; Zimmermann, Wolfram-Hubertus; Wollnik, Bernd; Cyganek, Lukas

Human serum-derived α-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-02-28

OAAI

Garg, Pretty; Wuertz, Franziska; Hobbie, Fabian; Buttgereit, Klemens; Aich, Abhishek; Leite, Kristian; Rehling, Peter; Kuegler, Sebastian; Baehr, Mathias

S-SCAM is essential for synapse formation

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2023-11-16

OAAI

Wittenmayer, Nina; Petkova-Tuffy, Andonia; Borgmeyer, Maximilian; Lee, Chungku; Becker, Juergen; Boening, Andreas; Kuegler, Sebastian; Rhee, Jeongseop; Viotti, Julio S.; Dresbach, Thomas

Fibroblast growth factor 9 (FGF9)-mediated neurodegeneration: Implications for progressive multiple sclerosis?

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

IF3.4

2023-10-05

OAAI

Thummler, Katja; Wrzos, Claudia; Franz, Jonas; McElroy, Daniel; Cole, John J.; Hayden, Lorna; Arseni, Diana; Schwarz, Friedrich; Junker, Andreas; Edgar, Julia M.; Kuegler, Sebastian; Neef, Andreas; Wolf, Fred; Stadelmann, Christine; Linington, Christopher

α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2022-05-03

OAAI

Leite, Kristian; Garg, Pretty; Spitzner, F. Paul; Guerin Darvas, Sofia; Baehr, Mathias; Priesemann, Viola; Kuegler, Sebastian

Generation and Breeding of EGFP-Transgenic Marmoset Monkeys: Cell Chimerism and Implications for Disease Modeling

CELLS

IF5.2

2021-02-27

OAAI

Drummer, Charis; Vogt, Edgar-John; Heistermann, Michael; Roshani, Berit; Becker, Tamara; Matz-Rensing, Kerstin; Kues, Wilfried A.; Kugler, Sebastian; Behr, Rudiger

Syntenin-knock out reduces exosome turnover and viral transduction

SCIENTIFIC REPORTS

IF3.9

2021-02-18

OAAI

Kashyap, Rudra; Balzano, Marielle; Lechat, Benoit; Lambaerts, Kathleen; Egea-Jimenez, Antonio Luis; Lembo, Frederique; Fares, Joanna; Meeussen, Sofie; Kuegler, Sebastian; Roebroek, Anton; David, Guido; Zimmermann, Pascale

Dementia with Lewy bodies-associated β-synuclein mutations V70M and P123H cause mutation-specific neuropathological lesions

HUMAN MOLECULAR GENETICS

IF3.2

2021-02-10

OAAI

Psol, Maryna; Darvas, Sofia Guerin; Leite, Kristian; Mahajani, Sameehan U.; Baehr, Mathias; Kuegler, Sebastian

Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery 与AAV1 & 2和AAV9相比，全身AAV6-synapsin-GFP给药导致较低的肝脏生物分布，在超声介导的脑递送后神经元表达

SCIENTIFIC REPORTS

IF3.9

2021-01-21

OAAI

Weber-Adrian, Danielle; Kofoed, Rikke Hahn; Silburt, Joseph; Noroozian, Zeinab; Shah, Kairavi; Burgess, Alison; Rideout, Shawna; Kuegler, Sebastian; Hynynen, Kullervo; Aubert, Isabelle

Patterning inconsistencies restrict the true potential of dopaminergic neurons derived from human induced pluripotent stem cells

NEURAL REGENERATION RESEARCH

IF6.7

2021-01-01

OAAI

Mahajani, Sameehan; Baehr, Mathias; Kuegler, Sebastian

Overshooting Subcellular Redox-Responses in Rett-Mouse Hippocampus during Neurotransmitter Stimulation

CELLS

IF5.2

2020-11-24

OAAI

Festerling, Karina; Can, Karolina; Kuegler, Sebastian; Mueller, Michael

Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors

CELL DEATH & DISEASE

IF9.6

2019-11-27

OAAI

Mahajani, Sameehan; Raina, Anupam; Fokken, Claudia; Kugler, Sebastian; Baehr, Mathias

Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release

FRONTIERS IN PHYSIOLOGY

IF3.4

2019-04-30

OAAI

Can, Karolina; Menzfeld, Christiana; Rinne, Lena; Rehling, Peter; Kuegler, Sebastian; Golubiani, Gocha; Dudek, Jan; Mueller, Michael

Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease 在阿尔茨海默氏病小鼠模型中增强淀粉样斑块附近转基因表达的策略

THERANOSTICS

IF13.3

2019-01-01

OAAI

Weber-Adrian, Danielle; Kofoed, Rikke Hahn; Chan, Josephine Wing Yee; Silburt, Joseph; Noroozian, Zeinab; Kuegler, Sebastian; Hynynen, Kullervo; Aubert, Isabelle

A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice

EMBO MOLECULAR MEDICINE

IF8.3

2018-12-03

144

OAAI

Al-Moyed, Hanan; Cepeda, Andreia P.; Jung, SangYong; Moser, Tobias; Kuegler, Sebastian; Reisinger, Ellen

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

HUMAN MOLECULAR GENETICS

IF3.2

2018-09-13

136

OAAI

Pinho, Raquel; Paiva, Isabel; Jercic, Kristina Gotovac; Fonseca-Ornelas, Luis; Gerhardt, Ellen; Fahlbusch, Christiane; Garcia-Esparcia, Paula; Kerimoglu, Cemil; Pavlou, Maria A. S.; Villar-Pique, Anna; Szego, Eva; da Fonseca, Tomas Lopes; Odoardi, Francesca; Soeroes, Szabolcs; Rego, Ana Cristina; Fischle, Wolfgang; Schwamborn, Jens C.; Meyer, Thomas; Kuegler, Sebastian; Ferrer, Isidre; Attems, Johannes; Fischer, Andre; Becker, Stefan; Zweckstetter, Markus; Borovecki, Fran; Outeiro, Tiago F.

Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model (vol 7, e2359, 2016)

CELL DEATH & DISEASE

IF9.6

2018-05-25

OAAI

Drinkut, Anja; Tillack, Karsten; Meka, Durga P.; Schulz, Jorg B.; Kuegler, Sebastian; Kramer, Edgar R.

Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2018-03-07

OAAI

Toloe, Johan; Taschenberger, Grit; Leite, Kristian; Stahlberg, Markus A.; Spehlbrink, Gesche; Kues, Janina; Munari, Francesca; Capaldi, Stefano; Becker, Stefan; Zweckstetter, Markus; Dean, Camin; Baehr, Mathias; Kuegler, Sebastian

A MicroRNA124 Target Sequence Restores Astrocyte Specificity of gfaABC1D-Driven Transgene Expression in AAV-Mediated Gene Transfer

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2017-09-01

OAAI

Taschenberger, Grit; Tereshchenko, Julia; Kuegler, Sebastian

研究方向