Philipp Koldewey - Publications, H-index & Citations

Philipp Koldewey

roche holding

15H指数

29论文数

1.1K被引数

收录论文 18

发表时间

Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-09-30

PREAI

Obst-Sander, Ulrike; Ricci, Antonio; Kuhn, Bernd; Friess, Thomas; Koldewey, Philipp; Kuglstatter, Andreas; Hewings, David; Goergler, Annick; Steiner, Sandra; Rueher, Daniel; Imhoff, Marie-Paule; Raschetti, Noemi; Marty, Hans-Peter; Dietzig, Aline; Rynn, Caroline; Ehler, Andreas; Burger, Dominique; Kornacker, Martin; Schaffland, Jeannine Petrig; Herting, Frank; Pao, William; Bischoff, James R.; Martoglio, Bruno; Nagel, Yvonne Alice; Jaeschke, Georg

Chemical, Analytical and Pharmacokinetic Characterisation of RO7304898, an API Consisting of Two Rapidly Interconverting Diastereoisomers

PHARMACEUTICAL RESEARCH

IF4.3

2022-03-25

PREAI

Heinig, Katja; Sladojevich, Filippo; Schaffland, Jeannine Petrig; Jaeschke, Georg; Ross, Alfred; Koldewey, Philipp; Miladinovic, Sasa M.; Wang, Jin; Rynn, Caroline

Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Richter, Kirsten; Rufer, Arne C.; Muller, Magali; Burger, Dominique; Casagrande, Fabio; Grossenbacher, Tabea; Huber, Sylwia; Hug, Melanie N.; Koldewey, Philipp; D'Osualdo, Andrea; Schlatter, Daniel; Stoll, Theodor; Rudolph, Markus G.

Small molecule AX-024 reduces T cell proliferation independently of CD3?/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-06-01

OAAI

Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket 区域着丝粒上的cenp-c cupin结构域的结构揭示了内袋的二聚化和募集功能的独特模式

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-09-01

OAAI

Chik, Jennifer K.; Moiseeva, Vera; Goel, Pavitra K.; Meinen, Ben A.; Koldewey, Philipp; An, Sojin; Mellone, Barbara G.; Subramanian, Lakxmi; Cho, Uhn-Soo

Reply to 'Misreading chaperone-substrate complexes from random noise'

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2018-10-08

PREAI

Horowitz, Scott; Salmon, Loic; Koldewey, Philipp; Ahlstrom, Logan S.; Martin, Raoul; Quan, Shu; Afonine, Pavel V.; van den Bedem, Henry; Wang, Lili; Xu, Qingping; Trievel, Raymond C.; Brooks, Charles L., III; Bardwell, James C. A.

Folding while bound to chaperones

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2018-02-01

OAAI

Horowitz, Scott; Koldewey, Philipp; Stull, Frederick; Bardwell, James C. A.

Chaperone-client interactions: Non-specificity engenders multifunctionality

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-07-01

OAAI

Koldewey, Philipp; Horowitz, Scott; Bardwell, James C. A.

Evaluation of de novo-designed coiled coils as offthe-shelf components for protein assembly

MOLECULAR SYSTEMS DESIGN & ENGINEERING

IF3.2

2017-01-01

PREAI

Cristie-David, Ajitha S.; Sciore, Aaron; Badieyan, Somayesadat; Escheweiler, Joseph D.; Koldewey, Philipp; Bardwell, James C. A.; Ruotolo, Brandon T.; Marsh, E. Neil G.

Determining crystal structures through crowdsourcing and coursework (vol 7, 12549, 2016)

NATURE COMMUNICATIONS

IF15.7

2016-10-25

OAAI

Horowitz, Scott; Koepnick, Brian; Martin, Raoul; Tymieniecki, Agnes; Winburn, Amanda A.; Cooper, Seth; Flatten, Jeff; Rogawski, David S.; Koropatkin, Nicole M.; Hailu, Tsinatkeab T.; Jain, Neha; Koldewey, Philipp; Ahlstrom, Logan S.; Chapman, Matthew R.; Sikkema, Andrew P.; Skiba, Meredith A.; Maloney, Finn P.; Beinlich, Felix R. M.; Players, Foldit

Determining crystal structures through crowdsourcing and coursework

NATURE COMMUNICATIONS

IF15.7

2016-09-16

OAAI

Flexible, symmetry-directed approach to assembling protein cages

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-07-18

OAAI

Sciore, Aaron; Su, Min; Koldewey, Philipp; Eschweiler, Joseph D.; Diffley, Kelsey A.; Linhares, Brian M.; Ruotolo, Brandon T.; Bardwell, James C. A.; Skiniotis, Georgios; Marsh, E. Neil G.

Visualizing chaperone-assisted protein folding

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2016-05-30

OAAI

Substrate protein folds while it is bound to the ATP-independent chaperone Spy

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2015-11-30

OAAI

Stull, Frederick; Koldewey, Philipp; Humes, Julia R.; Radford, Sheena E.; Bardwell, James C. A.

HdeB functions as an acid-protective chaperone in bacteria (vol 290, pg 65, 2015)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-04-01

OAAI

Dahl, Jan-Ulrik; Koldewey, Philipp; Salmon, Loic; Horowitz, Scott; Bardwell, James C. A.; Jakob, Ursula

Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum 线粒体过氧化物酶在婴儿利什曼原虫中起着至关重要的伴侣库的作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-02-02

OAAI

Teixeira, Filipa; Castro, Helena; Cruz, Tania; Tse, Eric; Koldewey, Philipp; Southworth, Daniel R.; Tomas, Ana M.; Jakob, Ursula

HdeB Functions as an Acid-protective Chaperone in Bacteria

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-01-01

OAAI

Dahl, Jan-Ulrik; Koldewey, Philipp; Salmon, Loic; Horowitz, Scott; Bardwell, James C. A.; Jakob, Ursula

Genetic selection designed to stabilize proteins uncovers a chaperone called Spy

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2011-02-13

154

OAAI

Quan, Shu; Koldewey, Philipp; Tapley, Tim; Kirsch, Nadine; Ruane, Karen M.; Pfizenmaier, Jennifer; Shi, Rong; Hofmann, Stephan; Foit, Linda; Ren, Guoping; Jakob, Ursula; Xu, Zhaohui; Cygler, Miroslaw; Bardwell, James C. A.

研究方向