未登录 Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations Khor, Chiea Chuen; Winter, Stefan; Sutiman, Natalia; Muerdter, Thomas E.; Chen, Sylvia; Lim, Joanne Siok Liu; Li, Zheng; Li, Jingmei; Sim, Kar Seng; Ganchev, Boian; Eccles, Diana; Eccles, Bryony; Tapper, William; Zgheib, Nathalie K. K.; Tfayli, Arafat; Ng, Raymond Chee Hui; Yap, Yoon Sim; Lim, Elaine; Wong, Mabel; Wong, Nan Soon; Ang, Peter Cher Siang; Dent, Rebecca; Tremmel, Roman; Klein, Kathrin; Schaeffeler, Elke; Zhou, Yitian; Lauschke, Volker M. M.; Eichelbaum, Michel; Schwab, Matthias; Brauch, Hiltrud B. B.; Chowbay, Balram; Schroth, Werner 分享 收藏
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The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes Johaenning, Janina; Kroener, Patrick; Thomas, Maria; Zanger, Ulrich M.; Noerenberg, Astrid; Eichelbaum, Michel; Schwab, Matthias; Brauch, Hiltrud; Schroth, Werner; Muerdter, Thomas E. 分享 收藏
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Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique Actis-Goretta, Lucas; Leveques, Antoine; Rein, Maarit; Teml, Alexander; Schaefer, Christian; Hofmann, Ute; Li, Hequn; Schwab, Matthias; Eichelbaum, Michel; Williamson, Gary 分享 收藏
CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations Province, M. A.; Goetz, M. P.; Brauch, H.; Flockhare, D. A.; Hebert, J. M.; Whaley, R.; Suman, V. J.; Schroth, W.; Winter, S.; Zembutsu, H.; Mushiroda, T.; Newman, W. G.; Lee, M-T M.; Ambrosone, C. B.; Beckmann, M. W.; Choi, J-Y; Dieudonne, A-S; Fasching, P. A.; Ferraldeschi, R.; Gong, L.; Haschke-Becher, E.; Howel, A.; Jordan, L. B.; Hamann, U.; Kiyotani, K.; Krippl, P.; Lambrechts, D.; Latif, A.; Langsenlehner, U.; Lorizio, W.; Neven, P.; Nguyen, A. T.; Park, B-W; Purdie, C. A.; Quinlan, P.; Renner, W.; Schmidt, M.; Schwab, M.; Shin, J-G; Stingl, J. C.; Wegman, P.; Wingren, S.; Wu, A. H. B.; Ziv, E.; Zirpoli, G.; Thompson, A. M.; Jordan, V. C.; Nakamura, Y.; Altman, R. B.; Ames, M. M.; Weinshilboum, R. M.; Eichelbaum, M.; Ingle, J. N.; Klein, T. E. 分享 收藏
Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles Lucena, M. Isabel; Molokhia, Mariam; Shen, Yufeng; Urban, Thomas J.; Aithal, Guruprasad P.; Andrade, Raul J.; Day, Christopher P.; Ruiz-Cabello, Francisco; Donaldson, Peter T.; Stephens, Camilla; Pirmohamed, Munir; Romero-Gomez, Manuel; Maria Navarro, Jose; Fontana, Robert J.; Miller, Michael; Groome, Max; Bondon-Guitton, Emmanuelle; Conforti, Anita; Stricker, Bruno H. C.; Carvajal, Alfonso; Ibanez, Luisa; Yue, Qun-Ying; Eichelbaum, Michel; Floratos, Aris; Pe'er, Itsik; Daly, Mark J.; Goldstein, David B.; Dillon, John F.; Nelson, Matthew R.; Watkins, Paul B.; Daly, Ann K. 分享 收藏
Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in Plasma Muerdter, T. E.; Schroth, W.; Bacchus-Gerybadze, L.; Winter, S.; Heinkele, G.; Simon, W.; Fasching, P. A.; Fehm, T.; Eichelbaum, M.; Schwab, M.; Brauch, H. 分享 收藏
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The Impact of Thyroid Disease on the Regulation, Expression, and Function of ABCB1 (MDR1/P-Glycoprotein) and Consequences for the Disposition of Digoxin Burk, O.; Brenner, S. S.; Hofmann, U.; Tegude, H.; Igel, S.; Schwab, M.; Eichelbaum, M.; Alscher, M. D. 分享 收藏
Effect of CYP2B6, ABCB1, and CYP3A5 Polymorphisms on Efavirenz Pharmacokinetics and Treatment Response: An AIDS Clinical Trials Group Study Ribaudo, Heather J.; Liu, Huan; Schwab, Matthias; Schaeffeler, Elke; Eichelbaum, Michel; Motsinger-Reif, Alison A.; Ritchie, Marylyn D.; Zanger, Ulrich M.; Acosta, Edward P.; Morse, Gene D.; Gulick, Roy M.; Robbins, Gregory K.; Clifford, David; Haas, David W. 分享 收藏
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Genetic Influences on the Pharmacokinetics of Orally and Intravenously Administered Digoxin as Exhibited by Monozygotic Twins Birkenfeld, A. L.; Jordan, J.; Hofmann, U.; Busjahn, A.; Franke, G.; Krueger, N.; Igel, S.; Muerdter, T.; Drescher, S.; Shi, S.; Engeli, S.; Schwab, M.; Eichelbaum, M.; Luft, F. C.; Fromm, M. F. 分享 收藏
A Polymorphism in the TC21 Promoter Associates with an Unfavorable Tamoxifen Treatment Outcome in Breast Cancer Rokavec, Matjaz; Schroth, Werner; Amaral, Sandra M. C.; Fritz, Peter; Antoniadou, Lydia; Glavac, Damjan; Simon, Wolfgang; Schwab, Matthias; Eichelbaum, Michel; Branch, Hiltrud 分享 收藏
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Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms Ji, Yuan; Olson, Janet; Zhang, Jianping; Hildebrandt, Michelle; Wang, Liewei; Ingle, James; Fredericksen, Zachary; Sellers, Thomas; Miller, William; Dixon, J. Michael; Branch, Hiltrud; Eichelbaum, Michel; Justenhoven, Christina; Hamann, Ute; Ko, Yon; Bruening, Thomas; Chang-Claude, Jenny; Wang-Gohrke, Shan; Schaid, Daniel; Weinshilboum, Richard 分享 收藏
Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery:: A randomized, double-blind placebo-controlled trial Moerike, K.; Kivistoe, K. T.; Schaeffeler, E.; Jaegle, C.; Igel, S.; Drescher, S.; Fux, R.; Marx, C.; Hofmann, U.; Engel, C.; Wagner, F.; Delabar, U.; Meisner, C.; Bail, D.; Boehm, J. O.; Gleiter, C. H.; Ziemer, G.; Rein, J. G.; Hellberg, K. D.; Eichelbaum, M.; Schwab, M. 分享 收藏
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