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Characterization of Selective M5 Acetylcholine Muscarinic Receptor Modulators on Dopamine Signaling in the Striatum Zell, Vivien; Teuns, Greetje; Needham, Alexandra Stormy; Mukherjee, Sruti; Roscoe, Nathaniel; Le, Michelle; Fourgeaud, Lawrence; Woodruff, Grace; Bhattacharya, Anindya; Marella, Mathieu; Bonaventure, Pascal; Drevets, Wayne C.; Balana, Bartosz 分享 收藏
The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice Smith, Jonathon; Mendez, Aida Menendez; Alves, Mariana; Parras, Alberto; Conte, Giorgia; Bhattacharya, Anindya; Ceusters, Marc; Nicke, Annette; Henshall, David C.; Jimenez-Mateos, Eva M.; Engel, Tobias 分享 收藏
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Functional α6β4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties Knowland, Daniel; Gu, Shenyan; Eckert, William A., III; Dawe, G. Brent; Matta, Jose A.; Limberis, James; Wickenden, Alan D.; Bhattacharya, Anindya; Bredt, David S. 分享 收藏
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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18F-JNJ-64413739, a PET Radioligand for P2X7 Receptors Kolb, Hartmuth C.; Barrett, Olivier; Bhattacharya, Anindya; Chen, Gang; Constantinescu, Cristian; Huang, Chaofeng; Letavic, Michael; Tamagnan, Gilles; Xia, Chunfang A.; Zhang, Wei; Szardenings, Anna Katrin 分享 收藏
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PET Imaging of the P2X7 Ion Channel with a Novel Tracer [18F]JNJ-64413739 in a Rat Model of Neuroinflammation Berdyyeva, Tamara; Xia, Chunfang; Taylor, Natalie; He, Yingbo; Chen, Gang; Huang, Chaofeng; Zhang, Wei; Kolb, Hartmuth; Letavic, Michael; Bhattacharya, Anindya; Szardenings, Anna Katrin 分享 收藏
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Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia Bhattacharya, Anindya; Lord, Brian; Grigoleit, Jan-Sebastian; He, Yingbo; Fraser, Ian; Campbell, Shannon N.; Taylor, Natalie; Aluisio, Leah; O'Connor, Jason C.; Papp, Mariusz; Chrovian, Christa; Carruthers, Nicholas; Lovenberg, Timothy W.; Letavic, Michael A. 分享 收藏
Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation Zou, Yanan; Chen, Zixuan; Jennings, Brett L.; Zhao, Guannan; Gu, Qingqing; Bhattacharya, Anindya; Cui, Yan; Yu, Bo; Malik, Kafait U.; Yue, Junming 分享 收藏
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate Chrovian, Christa C.; Soyode-Johnson, Akinola; Peterson, Alexander A.; Gelin, Christine F.; Deng, Xiaohu; Dvorak, Curt A.; Carruthers, Nicholas I.; Lord, Brian; Fraser, Ian; Aluisio, Leah; Coe, Kevin J.; Scott, Brian; Koudriakova, Tatiana; Schoetens, Freddy; Sepassi, Kia; Gallacher, David J.; Bhattacharya, Anindya; Letavic, Michael A. 分享 收藏
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Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits Huan, Tianxiao; Chen, George; Liu, Chunyu; Bhattacharya, Anindya; Rong, Jian; Chen, Brian H.; Seshadri, Sudha; Tanriverdi, Kahraman; Freedman, Jane E.; Larson, Martin G.; Murabito, Joanne M.; Levy, Daniel 分享 收藏
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4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate Letavic, Michael A.; Savall, Brad M.; Allison, Brett D.; Aluisio, Leah; Andres, Jose Ignacio; De Angelis, Meri; Ao, Hong; Beauchamp, Derek A.; Bonaventure, Pascal; Bryan, Stewart; CarruthersT, Nicholas I.; Ceusters, Marc; Coe, Kevin J.; Dvorak, Curt A.; Fraser, Ian C.; Gelin, Christine F.; Koudriakova, Tatiana; Liang, Jimmy; Lord, Brian; Lovenberg, Timothy W.; Otieno, Monicah A.; Schoetens, Freddy; Swanson, Devin M.; Wang, Qi; Wickenden, Alan D.; Bhattacharyat, Anindya 分享 收藏
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