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Late Breaking Abstract- Bexotegrast reduces type 1 collagen deposition in participants with idiopathic pulmonary fibrosis (IPF) after 12 weeks of therapy Montesi, Sydney B.; Cosgrove, Gregory P.; Turner, Scott; Zhou, Iris; Efthimiou, Nikos; Susnjar, Antonia; Catana, Ciprian; Fromson, Caroline; Clark, Annie; Decaris, Martin; Barnes, Chris N.; Lefebvre, Eric A.; Caravan, Peter 分享 收藏
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Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis The INTEGRIS-IPF Clinical Trial Beexotegrast在特发性肺纤维化患者中的integriis-IPF临床试验 Lancaster, Lisa; Cottin, Vincent; Ramaswamy, Murali; Wuyts, Wim A.; Jenkins, R. Gisli; Scholand, Mary Beth; Kreuter, Michael; Valenzuela, Claudia; Ryerson, Christopher J.; Goldin, Jonathan; Kim, Grace Hyun J.; Jurek, Marzena; Decaris, Martin; Clark, Annie; Turner, Scott; Barnes, Chris N.; Achneck, Hardean E.; Cosgrove, Gregory P.; Lefebvre, Eric A.; Flaherty, Kevin R. 分享 收藏
Late Breaking Abstract - Safety, tolerability and antifibrotic activity of bexotegrast: Phase 2a INTEGRISIPF study (NCT04396756) Wuyts, Wim A.; Valenzuela, Claudia; Jenkins, Gisli; Goldin, Jonathan G.; Kim, Grace Hyun J.; Jurek, Marzena; Turner, Scott; Decaris, Martin; Barnes, Chris N.; Lefebvre, Eric; Cosgrove, Gregory; Cottin, Vincent 分享 收藏
Comparison of ADAPT, FIB-4 and APRI as non-invasive predictors of liver fibrosis and NASH within the CENTAUR screening population 在CENTAUR筛查人群中，ADAPT，FIB-4和APRI作为肝纤维化和NASH的非侵入性预测指标的比较 Nielsen, Mette Juul; Leeming, Diana Julie; Goodman, Zachary; Friedman, Scott; Frederiksen, Peder; Rasmussen, Daniel Guldager Kring; Vig, Pamela; Seyedkazemi, Star; Fischer, Laurent; Torstenson, Richard; Karsdal, Morten Asser; Lefebvre, Eric; Sanyal, Arun J.; Ratziu, Vlad 分享 收藏
Efficacy and Safety of Cenicriviroc in Patients With Primary Sclerosing Cholangitis: PERSEUS Study Eksteen, Bertus; Bowlus, Christopher L.; Montano-Loza, Aldo J.; Lefebvre, Eric; Fischer, Laurent; Vig, Pamela; Martins, Eduardo Bruno; Ahmad, Jawad; Yimam, Kidist K.; Pockros, Paul J.; Feld, Jordan J.; Minuk, Gerald; Levy, Cynthia 分享 收藏
INTEGRIS-IPF: a 12-week, Phase 2a study evaluating the safety, tolerability and pharmacokinetics of PLN-74809 in participants with IPF Lefebvre, Eric; Coulie, Bernard; Jurek, Marzena; Bellini, Jonathan; Cilli, Fiona; Wong, Simon; Decaris, Martin; Turner, Scott; Park, Erica 分享 收藏
Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease Vos, Miriam B.; Dimick-Santos, Lara; Mehta, Ruby; Omokaro, Stephanie O.; Taminiau, Johannes; Schabel, Elmer; Kleiner, David E.; Szitanyi, Peter; Socha, Piotr; Schwimmer, Jeffrey B.; Noviello, Stephanie; Silberg, Debra G.; Torstenson, Richard; Miller, Veronica; Lavine, Joel E.; Adda, Nathalie; Baldyga, William; Banerjee, Rajarshi; Behling, Cynthia; Boulos, Sherif; Burgess, Gary; Calboli, Dania; Charles, Edgar; Christian, Rose; Cohen-Bacrie, Claude; Cosma-Roman, Doina; Danzer, Claus-Peter; Delaet, Ingrid; Delegge, Mark; Dimick-Santos, Lara; DiProspero, Nicholas; Donohue, Kathleen; Fischer, Laurent; Fitzpatrick, Emer; Fried, Michael; Hagerty, David; Hale, Paula; Hildick, Keri; Hum, Dean; Jamil, Khurram; Jiang, Lijuan; Karpen, Saul; Kelly, Matt; Kleiner, David E.; Kohli, Rohit; Kordy, Kattayoun; Krieger, Nancy; Lavine, Joel; Lee, Lois; Lefebvre, Eric; Lopez, Patricia; Lyons, Erica; Malahias, Laura; Megnien, Sophie; Mehta, Ruby; Mesenbrink, Peter; Miller, Veronica; Minnick, Pansy; Murray, Christine; Nghiem, Tien; Nicholson, Nikki; Noviello, Stephanie; Omokaro, Stephanie O.; Pang, Wenjie; Percival, Lisa; Peres, Dan; Powell, Margaret; Roman, Dragos; Root, Mark; Sampson, Claire; Sanyal, Arun; Schabel, Elmer; Schwarz, Kathleen; Schwimmer, Jeffrey B.; Seyedkazemi, Star; Shapiro, David; Shringarpure, Reshma; Silberg, Debra; Smith, Edward; Socha, Piotr; Squires, Robert; Szitanyi, Peter; Taminiau, Johannes; Torstenson, Richard; Treem, William; Vig, Pamela; Vos, Miriam; Yamashita, Mason; Zemel, Michael 分享 收藏
Dual aVβ6/aVβ1 inhibitor PLN-74809 blocks multiple TGF-β activation pathways associated with IPF Decaris, Martin; Schaub, Johanna; Chen, Chun; Cha, Jake; Reilly, Maureen; Lee, Gail; Rexhepaj, Megi; Rao, Vikram; Kotak, Prerna; Hooi, Lisa; Wu, Jianfeng; Martin, Shamra; Chen, Tony; Munoz, Manuel; Cooper, Nicole; Hom, Timothy; Leftheris, Katerina; Andre, Patrick; Gorina, Eduard; Lefebvre, Eric; Turner, Scott 分享 收藏
Late Breaking Abstract - PK/PD assessment of an oral, selective aVβ6/aVβ1 integrin dual antagonist, PLN-748o9, for the treatment of idiopathic pulmonary fibrosis Turner, Scott; Lepist, Eve Irene; Rock, Fernando; Decaris, Martin; Schaub, Johanna; Chen, Chun; Gorina, Eduard; Lefebvre, Eric 分享 收藏
Rates of and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis 非酒精性脂肪性肝炎药物治疗试验中安慰剂应答率及相关因素: 系统回顾和荟萃分析 Han, Ma Ai Thanda; Altayar, Osama; Hamdeh, Shadi; Takyar, Varun; Rotman, Yaron; Etzion, Ohad; Lefebvre, Eric; Safadi, Rifaat; Ratziu, Vlad; Prokop, Larry J.; Murad, Mohammad Hassan; Noureddin, Mazen 分享 收藏
Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice Ambade, Aditya; Lowe, Patrick; Kodys, Karen; Catalano, Donna; Gyongyosi, Benedek; Cho, Yeonhee; Iracheta-Vellve, Arvin; Adejumo, Adeyinka; Saha, Banishree; Calenda, Charles; Mehta, Jeeval; Lefebvre, Eric; Vig, Pamela; Szabo, Gyongyi 分享 收藏
Development and validation of the TROLL radiation-hydrodynamics code for 3D hohlraum calculations Lefebvre, E.; Bernard, S.; Esnault, C.; Gauthier, P.; Grisollet, A.; Hoch, P.; Jacquet, L.; Kluth, G.; Laffite, S.; Liberatore, S.; Marmajou, I.; Masson-Laborde, P. -E.; Morice, O.; Willien, J. -L. 分享 收藏
The Critical Role of Chemokine (C-C Motif) Receptor 2-Positive Monocytes in Autoimmune Cholangitis Reuveni, Debby; Gore, Yael; Leung, Patrick S. C.; Lichter, Yael; Moshkovits, Itay; Kaminitz, Ayelet; Brazowski, Eli; Lefebvre, Eric; Vig, Pamela; Varol, Chen; Halpern, Zamir; Shibolet, Oren; Gershwin, Merrill Eric; Zigmond, Ehud 分享 收藏
Cenicriviroc inhibits trans-endothelial passage of monocytes and is associated with impaired E-selectin expression D'Antoni, Michelle L.; Mitchell, Brooks I.; McCurdy, Sara; Byron, Mary Margaret; Ogata-Arakaki, Debra; Chow, Dominic; Mehta, Nehal N.; Boisvert, William A.; Lefebvre, Eric; Shikuma, Cecilia M.; Ndhlovu, Lishomwa C.; Baumer, Yvonne 分享 收藏
APOBEC3G/3A Expression in Human Immunodeficiency Virus Type 1-Infected Individuals Following Initiation of Antiretroviral Therapy Containing Cenicriviroc or Efavirenz Covino, Daniela A.; Purificato, Cristina; Catapano, Laura; Galluzzo, Clementina M.; Gauzzi, Maria Cristina; Vella, Stefano; Lefebvre, Eric; Seyedkazemi, Star; Andreotti, Mauro; Fantuzzi, Laura 分享 收藏
Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis Krenkel, Oliver; Puengel, Tobias; Govaere, Olivier; Abdallah, Ali T.; Mossanen, Jana C.; Kohlhepp, Marlene; Liepelt, Anke; Lefebvre, Eric; Luedde, Tom; Hellerbrand, Claus; Weiskirchen, Ralf; Longerich, Thomas; Costa, Ivan G.; Anstee, Quentin M.; Trautwein, Christian; Tacke, Frank 分享 收藏
Cenicriviroc treatment for adults with non-alcoholic steatohepatitis: Year 2 analysis of the Phase 2b CENTAUR study Ratziu, V.; Sanyal, A.; Francque, S.; Sun, W.; Wong, V.; Loomba, R.; Goodman, Z.; Lefebvre, E.; Aithal, G.; Harrison, S.; Abdelmalek, M.; Friedman, S.; Tacke, F. 分享 收藏
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