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Pharmacometabolomics applied to low-dose interleukin-2 treatment in amyotrophic lateral sclerosis Alarcan, Hugo; Bruno, Clement; Emond, Patrick; Raoul, Cedric; Vourc'h, Patrick; Corcia, Philippe; Camu, William; Veyrune, Jean-Luc; Garlanda, Cecilia; Locati, Massimo; Juntas-Morales, Raul; Saker, Safaa; Suehs, Carey; Masseguin, Christophe; Kirby, Janine; Shaw, Pamela; Malaspina, Andrea; De Vos, John; Al-Chalabi, Ammar; Leigh, P. Nigel; Tree, Timothy; Bensimon, Gilbert; Blasco, Helene 分享 收藏
Network connectivity and structural correlates of survival in progressive supranuclear palsy and corticobasal syndrome 进行性核上性麻痹和皮质基底节综合征的网络连通性和生存的结构相关性 Whiteside, David J.; Street, Duncan; Murley, Alexander G.; Jones, P. Simon; Malpetti, Maura; Ghosh, Boyd C. P.; Coyle-Gilchrist, Ian; Gerhard, Alexander; Hu, Michele T. T.; Klein, Johannes C.; Leigh, P. Nigel; Church, Alistair; Burn, David J.; Morris, Huw R.; Rowe, James B.; Rittman, Timothy 分享 收藏
Progression of atypical parkinsonian syndromes: PROSPECT-M-UK study implications for clinical trials 非典型帕金森综合征的进展: PROSPECT-m-uk研究对临床试验的影响 Street, Duncan; Jabbari, Edwin; Costantini, Alyssa; Jones, P. Simon; Holland, Negin; Rittman, Timothy; Jensen, Marte T.; Chelban, Viorica; Goh, Yen Y.; Guo, Tong; Heslegrave, Amanda J.; Roncaroli, Federico; Klein, Johannes C.; Ansorge, Olaf; Allinson, Kieren S. J.; Jaunmuktane, Zane; Revesz, Tamas; Warner, Thomas T.; Lees, Andrew J.; Zetterberg, Henrik; Russell, Lucy L.; Bocchetta, Martina; Rohrer, Jonathan D.; Burn, David J.; Pavese, Nicola; Gerhard, Alexander; Kobylecki, Christopher; Leigh, P. Nigel; Church, Alistair; Hu, Michele T. M.; Houlden, Henry; Morris, Huw; Rowe, James B. 分享 收藏
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Neurofilament light levels predict clinical progression and death in multiple system atrophy 神经丝光水平可预测多系统萎缩的临床进展和死亡 Chelban, Viorica; Nikram, Elham; Perez-Soriano, Alexandra; Wilke, Carlo; Foubert-Samier, Alexandra; Vijiaratnam, Nirosen; Guo, Tong; Jabbari, Edwin; Olufodun, Simisola; Gonzalez, Mariel; Senkevich, Konstantin; Laurens, Brice; Peran, Patrice; Rascol, Olivier; Le Traon, Anne Pavy; Todd, Emily G.; Costantini, Alyssa A.; Alikhwan, Sondos; Tariq, Ambreen; Ng, Bai Lin; Munoz, Esteban; Painous, Celia; Compta, Yaroslau; Junque, Carme; Segura, Barbara; Zhelcheska, Kristina; Wellington, Henny; Schoels, Ludger; Jaunmuktane, Zane; Kobylecki, Christopher; Church, Alistair; Hu, Michele T. M.; Rowe, James B.; Leigh, P. Nigel; Massey, Luke; Burn, David J.; Pavese, Nicola; Foltynie, Tom; Pchelina, Sofya; Wood, Nicholas; Heslegrave, Amanda J.; Zetterberg, Henrik; Bocchetta, Martina; Rohrer, Jonathan D.; Marti, Maria J.; Synofzik, Matthis; Morris, Huw R.; Meissner, Wassilios G.; Houlden, Henry 分享 收藏
Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2 Giovannelli, Ilaria; Bayatti, Nadhim; Brown, Abigail; Wang, Dennis; Mickunas, Marius; Camu, William; Veyrune, Jean-Luc; Payan, Christine; Garlanda, Cecilia; Locati, Massimo; Juntas-Morales, Raul; Pageot, Nicolas; Malaspina, Andrea; Andreasson, Ulf; Suehs, Carey; Saker, Safa; Masseguin, Christophe; de Vos, John; Zetterberg, Henrik; Al-Chalabi, Ammar; Leigh, P. Nigel; Tree, Timothy; Bensimon, Gilbert; Heath, Paul R.; Shaw, Pamela J.; Kirby, Janine 分享 收藏
Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis 肌萎缩侧索硬化症的潜在非编码RNA生物标志物特征的鉴定 Joilin, Greig; Gray, Elizabeth; Thompson, Alexander G.; Bobeva, Yoana; Talbot, Kevin; Weishaupt, Jochen; Ludolph, Albert; Malaspina, Andrea; Leigh, P. Nigel; Newbury, Sarah F.; Turner, Martin R.; Hafezparast, Majid 分享 收藏
Oral levosimendan in amyotrophic lateral sclerosis: a phase II multicentre, randomised, double-blind, placebo-controlled trial 口服左西孟旦治疗肌萎缩性侧索硬化症: 一项II期多中心、随机、双盲、安慰剂对照试验 Al-Chalabi, Ammar; Shaw, Pamela; Leigh, P. Nigel; van den Berg, Leonard; Hardiman, Orla; Ludolph, Albert; Aho, Valtteri V.; Sarapohja, Toni; Kuoppamaki, Mikko 分享 收藏
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Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases 进行性核上性麻痹的联合全基因组关联研究确定了新的易感位点以及与神经退行性疾病的遗传相关性 Chen, Jason A.; Chen, Zhongbo; Won, Hyejung; Huang, Alden Y.; Lowe, Jennifer K.; Wojta, Kevin; Yokoyama, Jennifer S.; Bensimon, Gilbert; Leigh, P. Nigel; Payan, Christine; Shatunov, Aleksey; Jones, Ashley R.; Lewis, Cathryn M.; Deloukas, Panagiotis; Amouyel, Philippe; Tzourio, Christophe; Dartigues, Jean-Francois; Ludolph, Albert; Boxer, Adam L.; Bronstein, Jeff M.; Al-Chalabi, Ammar; Geschwind, Daniel H.; Coppola, Giovanni 分享 收藏
Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials 肌萎缩侧索硬化临床试验中药物遗传学相互作用的Meta分析 van Eijk, Ruben P. A.; Jones, Ashley R.; Sproviero, William; Shatunov, Aleksey; Shaw, Pamela J.; Leigh, P. Nigel; Young, Carolyn A.; Shaw, Christopher E.; Mora, Gabriele; Mandrioli, Jessica; Borghero, Giuseppe; Volanti, Paolo; Diekstra, Frank P.; van Rheenen, Wouter; Verstraete, Esther; Eijkemans, Marinus J. C.; Veldink, Jan H.; Chio, Adriano; Al-Chalabi, Ammar; van den Berg, Leonard H.; van Es, Michael A. 分享 收藏
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NEK1 variants confer susceptibility to amyotrophic lateral sclerosis NEK1变体赋予肌萎缩性侧索硬化症易感性 Kenna, Kevin P.; van Doormaal, Perry T. C.; Dekker, Annelot M.; Ticozzi, Nicola; Kenna, Brendan J.; Diekstra, Frank P.; van Rheenen, Wouter; van Eijk, Kristel R.; Jones, Ashley R.; Keaglel, Pamela; Shatunov, Aleksey; Sproviero, William; Smiths, Bradley N.; van Es, Michael A.; Topps, Simon D.; Kenna, Aoife; Miller, Jack W.; Fallini, Claudia; Tiloca, Cinzia; McLaughlin, Russell L.; Vance, Caroline; Troakes, Claire; Colombrita, Claudia; Mora, Gabriele; Calvo, Andrea; Verde, Federico; Al-Sarraj, Safa; King, Andrew; Calini, Daniela; de Belleroche, Jacqueline; Baas, Frank; van der Kooi, Anneke J.; de Visser, Marianne; ten Asbroek, Anneloor L. M. A.; Sapp, Peter C.; McKenna-Yasek, Diane; Polak, Meraida; Asress, Seneshaw; Luis Munoz-Blanco, Jose; Strom, Tim M.; Meitinger, Thomas; Morrison, Karen E.; Lauria, Giuseppe; Williams, Kelly L.; Leigh, P. Nigel; Nicholson, Garth A.; Blair, Ian P.; Leblond, Claire S.; Dion, Patrick A.; Rouleau, Guy A.; Pall, Hardev; Shaw, Pamela J.; Turner, Martin R.; Talbot, Kevin; Taroni, Franco; Boylan, Kevin B.; Van Blitterswijk, Marka; Rademakers, Rosa; Esteban-Perez, Jesus; Garcia-Redondo, Alberto; Van Damme, Phillip; Robberecht, Wim; Chio, Adrian; Gellera, Cinzia; Drepper, Carsten; Sendtner, Michael; Ratti, Antonia; Glass, Jonathan D.; Mora, Jesus S.; Basak, Nazli A.; Hardiman, Orla; Ludolph, Albert C.; Andersen, Peter M.; Weishaupt, Jochen H.; Brown, Robert H., Jr.; Al-Chalabi, Ammar; Silani, Vincenzo; Shaw, Christopher E.; van den Berg, Leonard H.; Veldink, Jan H.; Landers, John E.; D'Alfonso, Sandra; Mazzini, Letizia; Comi, Giacomo P.; Del Bo, Roberto; Ceroni, Mauro; Gagliardi, Stella; Querin, Giorgia; Bertolin, Cinzia; Pensato, Viviana; Castellotti, Barbara; Corti, Stefania; Cereda, Cristina; Corrado, Lucia; Soraru, Gianni 分享 收藏
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis 全基因组关联分析确定肌萎缩侧索硬化症的新风险变异和遗传结构 van Rheenen, Wouter; Shatunov, Aleksey; Dekker, Annelot M.; McLaughlin, Russell L.; Diekstra, Frank P.; Pulit, Sara L.; van der Spek, Rick A. A.; Vosa, Urmo; de Jong, Simone; Robinson, Matthew R.; Yang, Jian; Fogh, Isabella; van Doormaal, Perry T. C.; Tazelaar, Gijs H. P.; Koppers, Max; Blokhuis, Anna M.; Sproviero, William; Jones, Ashley R.; Kenna, Kevin P.; van Eijk, Kristel R.; Harschnitz, Oliver; Schellevis, Raymond D.; Brands, William J.; Medic, Jelena; Menelaou, Androniki; Vajda, Alice; Ticozzi, Nicola; Lin, Kuang; Rogelj, Boris; Vrabec, Katarina; Ravnik-Glavac, Metka; Koritnik, Blazi; Zidar, Janez; Leonardis, Lea; Groselj, Leja Dolenc; Millecamps, Stephanie; Salachas, Francois; Meininger, Vincent; de Carvalho, Mamede; Pinto, Susana; Mora, Jesus S.; Rojas-Garcia, Ricardo; Polak, Meraida; Chandran, Siddharthan; Colville, Shuna; Swingler, Robert; Morrison, Karen E.; Shaw, Pamela J.; Hardy, John; Orrell, Richard W.; Pittman, Alan; Sidle, Katie; Fratta, Pietro; Malaspina, Andrea; Topp, Simon; Petri, Susanne; Abdulla, Susanne; Drepper, Carsten; Sendtner, Michael; Meyer, Thomas; Ophoff, Roel A.; Staats, Kim A.; Wiedau-Pazos, Martina; Lomen-Hoerth, Catherine; Van Deerlin, Vivianna M.; Trojanowski, John Q.; Elman, Lauren; McCluskey, Leo; Basak, A. Nazli; Tunca, Ceren; Hamzeiy, Hamid; Parman, Yesim; Meitinger, Thomas; Lichtner, Peter; Radivojkov-Blagojevic, Milena; Andres, Christian R.; Maurel, Cindy; Bensimon, Gilbert; Landwehrmeyer, Bernhard; Brice, Alexis; Payan, Christine A. M.; Saker-Delye, Safaa; Duerr, Alexandra; Wood, Nicholas W.; Tittmann, Lukas; Lieb, Wolfgang; Franke, Andre; Rietschel, Marcella; Cichon, Sven; Noethen, Markus M.; Amouyel, Philippe; Tzourio, Christophe; Dartigues, Jean-Francois; Uitterlinden, Andre G.; Rivadeneira, Fernando; Estrada, Karol; Hofman, Albert; Curtis, Charles; Blauw, Hylke M.; van der Kooi, Anneke J.; de Visser, Marianne; Goris, An; Weber, Markus; Shaw, Christopher E.; Smith, Bradley N.; Pansarasa, Orietta; Cereda, Cristina; Del Bo, Roberto; Comi, Giacomo P.; D'Alfonso, Sandra; Bertolin, Cinzia; Soraru, Gianni; Mazzini, Letizia; Pensato, Viviana; Gellera, Cinzia; Tiloca, Cinzia; Ratti, Antonia; Calvo, Andrea; Moglia, Cristina; Brunetti, Maura; Arcuti, Simona; Capozzo, Rosa; Zecca, Chiara; Lunetta, Christian; Penco, Silvana; Riva, Nilo; Padovani, Alessandro; Filosto, Massimiliano; Muller, Bernard; Stuit, Robbert Jan; Blair, Ian; Zhang, Katharine; McCann, Emily P.; Fifita, Jennifer A.; Nicholson, Garth A.; Rowe, Dominic B.; Pamphlett, Roger; Kiernan, Matthew C.; Grosskreutz, Julian; Witte, Otto W.; Ringer, Thomas; Prell, Tino; Stubendorff, Beatrice; Kurth, Ingo; Huebner, Christian A.; Leigh, P. Nigel; Casale, Federico; Chio, Adrian; Beghi, Ettore; Pupillo, Elisabetta; Tortelli, Rosanna; Logroscino, Giancarlo; Powell, John; Ludolph, Albert C.; Weishaupt, Jochen H.; Robberecht, Wim; Van Damme, Philip; Franke, Lude; Pers, Tune H.; Brown, Robert H.; Glass, Jonathan D.; Landers, John E.; Hardiman, Orla; Andersen, Peter M.; Corcia, Philippe; Vourc'h, Patrick; Silani, Vincenzo; Wray, Naomi R.; Visscher, Peter M.; de Bakker, Paul I. W.; van Es, Michael A.; Pasterkamp, R. Jeroen; Lewis, Cathryn M.; Breen, Gerome; Al-Chalabi, Ammar; van den Berg, Leonard H.; Veldink, Jan H. 分享 收藏
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