Håkan Wikström - Publications, H-index & Citations

Håkan Wikström

AstraZeneca

46H指数

169论文数

6.5K被引数

收录论文 62

发表时间

A review of the State-of-the-Art: progress in ultrasonic and acoustic techniques for quality assessment in the development and manufacturing of oral solid dosage forms-Part II: Applications and emerging directions 综述前沿：口服固体制剂开发与制造中超声和声学技术用于质量评估的进展—第二部分：应用与新兴方向

International Journal of Pharmaceutics

IF5.2

2026-05-01

PREAI

Cetinkaya, Cetin; Bazzocchi, Michael; Dave, Vivek S.; Halkude, Bhakti; Hussain, Ajaz S.; Vallabha, Chaitanya Krishna Prasad; Razavi, Sonia M.; Stephens, James; Steiner, Richard; Sultan, Tipu; Sun, Changquan Calvin; Tantuccio, Anthony S.; Tajarobi, Pirjo; Undey, Cenk; Wikstrom, Hakan; Xu, Xiaochi

Early prediction of tablet defects during pan coating 压片在滚筒包衣过程中的早期缺陷预测

European Journal of Pharmaceutical Sciences

IF4.7

2025-12-12

OAAI

Joona Sorjonen; Luis Martin de Juan; Pirjo Tajarobi; Håkan Wikström; Jarkko Ketolainen

A review of the state-of-the-art: progress in ultrasonic and acoustic techniques for quality assessment in the development and manufacturing of oral solid dosage forms − Part I: theoretical foundations and principles 技术综述：用于口服固体制剂开发与制造中质量评估的超声和声学技术进展——第一部分：理论基础与原理

International Journal of Pharmaceutics

IF5.2

2025-11-24

PREAI

Çetin Çetinkaya; Michael Bazzocchi; Vivek S. Dave; Bhakti Halkude; Ajaz S. Hussain; Chaitanya Krishna Prasad Vallabha; Sonia M. Razavi; James Stephens; Richard Steiner; Tipu Sultan; Calvin K. Sun; Anthony S. Tantuccio; Pirjo Tajarobi; Cenk Ündey; Håkan Wikström; Xiaochi Xu

Process robustness in twin-screw wet granulation: the role of formulation, screw configurations and liquid-to-solid ratios on milled granules and tablets 双螺杆湿法制粒的工艺稳健性：配方、螺杆配置和液固比对研磨颗粒和片剂的影响

International Journal of Pharmaceutics

IF5.2

2025-09-18

PREAI

Sally M. Karlsen; Håkan Wikström; Guzman Carissimi; Erik Walkhed; Fredrik Winge; Jukka Rantanen; Pirjo Tajarobi

Exploring the impact of formulation and tablet shape on tablet integrity: A comprehensive investigation using mechanical and imaging techniques 探索配方和片剂形状对片剂完整性的影响：一项使用机械和成像技术的综合研究

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2025-07-01

PREAI

Singhal, Mayank; Sorjonen, Joona; Wikstrom, Hakan; Upadhyay, Pratik; Alhusban, Farhan; Murphy, Dean; de Juan, Luis Martin; Ketolainen, Jarkko; Tajarobi, Pirjo

Drying capacity of a continuous vibrated fluid bed dryer - Statistical and mechanistic model development

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2023-10-01

PREAI

Wikstrom, Hakan; de Juan, Luis Martin; Remmelgas, Johan; Meier, Robin; Altmeyer, Andreas; Emanuele, Daniel; Jormanainen, Miika; Juppo, Anne; Tajarobi, Pirjo

Bench to batch: Linking pharmaceutical powder flow characterisation, intermediate bulk container discharge and video observations

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2023-03-01

PREAI

Megarry, Andrew; Wikstrom, Hakan; Bilen, Frida; Remmelgas, Johan; Liljeblad, Alexander; Tajarobi, Pirjo

Effect of shape on the physical properties of pharmaceutical tablets

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2022-08-01

OAAI

Sultan, Tipu; Xu, Xiaochi; Rozin, Enamul Hasan; Sorjonen, Joona; Ketolainen, Jarkko; Wikstrom, Hakan; de Juan, Luis Martin; Tajarobi, Pirjo; Cetinkaya, Cetin

Faster to First-time-in-Human: Prediction of the liquid solid ratio for continuous wet granulation

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2022-05-01

OAAI

Junnila, Atte; Wikstrom, Hakan; Megarry, Andrew; Gholami, Aida; Papathanasiou, Foteini; Blomberg, Andreas; Ketolainen, Jarkko; Tajarobi, Pirjo

Powder flow from an intermediate bulk container - Discharge predictions and experimental evaluation

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2021-03-01

PREAI

Wikstrom, Hakan; Remmelgas, Johan; Solin, Sara; Marucci, Mariagrazia; Sandler, Niklas; Boissier, Catherine; Tajarobi, Pirjo

Optical porosimetry by gas in scattering media absorption spectroscopy (GASMAS) applied to roller compaction ribbons

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2021-01-01

PREAI

Johansson, Jonas; Sparen, Anders; Wikstrom, Hakan; Tajarobi, Pirjo; Koch, Roland; Lundin, Patrik; Langberg, Anders; Sebesta, Mikael; Xu, Marta Lewander

Twin-screw granulation and high-shear granulation: The influence of mannitol grade on granule and tablet properties

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2020-11-01

PREAI

Megarry, Andrew; Taylor, Agnes; Gholami, Aida; Wikstrom, Hakan; Tajarobi, Pirjo

Symptoms of severe serotonin syndrome - A pooled case analysis

JOURNAL OF PSYCHOSOMATIC RESEARCH

IF3.3

2020-06-01

PREAI

Wikstrom, H.; Truedson, P.; Ott, M.; Werneke, U.

Robustness of a continuous direct compression line against disturbances in feeding

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2020-01-01

PREAI

Karttunen, A-P; Poms, J.; Sacher, S.; Sparen, A.; Samblas, C. Ruiz; Fransson, M.; De Juan, L. Martin; Remmelgas, J.; Wikstrom, H.; Hsiao, W-K; Folestad, S.; Korhonen, O.; Abrahmsen-Alami, S.; Tajarobi, P.

Characterization of microcrystalline cellulose spheres and prediction of hopper flow based on a μ(I)-rheology model

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2020-01-01

OAAI

Remmelgas, Johan; Fall, Abdoulaye; Sasic, Srdjan; Strom, Henrik; Tajarobi, Pirjo; Wikstrom, Hakan; Marucci, Mariagrazia; Boissier, Catherine

Comparison between integrated continuous direct compression line and batch processing - The effect of raw material properties

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2019-05-01

PREAI

Karttunen, Anssi-Pekka; Wikstrom, Hakan; Tajarobi, Pirjo; Fransson, Magnus; Sparen, Anders; Marucci, Mariagrazia; Ketolainen, Jarkko; Folestad, Staffan; Korhonen, Ossi; Abrahmsen-Alami, Susanna

Degradation caused by incompatibility between sodium stearyl fumarate (PRUV) and AZD7986 in the drug product

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2018-09-01

PREAI

Ludvigsson, Jufang Wu; Wikstrom, Hakan; Andersson, Thomas; Norrby, Per-Ola

Provoking an end-to-end continuous direct compression line with raw materials prone to segregation

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-11-01

PREAI

Lakio, Satu; Ervasti, Tuomas; Tajarobi, Pirjo; Wikstrom, Hakan; Fransson, Magnus; Karttunen, Anssi-Pekka; Ketolainen, Jarkko; Folestad, Staffan; Abrahmsen-Alami, Susanna; Korhonen, Ossi

Achieving a robust drug release from extended release tablets using an integrated continuous mixing and direct compression line

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2016-09-01

PREAI

Lakio, Satu; Tajarobi, Pirjo; Wikstrom, Hakan; Fransson, Magnus; Arnehed, Johan; Ervasti, Tuomas; Simonaho, Simo-Pekka; Ketolainen, Jarkko; Folestad, Staffan; Abrahmsen-Alami, Susanna

Continuous manufacturing of extended release tablets via powder mixing and direct compression

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2015-11-01

PREAI

Ervasti, Tuomas; Simonaho, Simo-Pekka; Ketolainen, Jarkko; Forsberg, Peter; Fransson, Magnus; Wikstrom, Hakan; Folestad, Staffan; Lakio, Satu; Tajarobi, Pirjo; Abrahmsen-Alami, Susanna

研究方向