未登录 NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo Namoto, Kenji; Baader, Clara; Orsini, Vanessa; Landshammer, Alexandro; Breuer, Eva; Dinh, Kieu Trinh; Ungricht, Rosemarie; Pikiolek, Monika; Laurent, Stephane; Lu, Bo; Aebi, Alexandra; Nberger, Katharina Schoenberger; Vangrevelinghe, Eric; Evrova, Olivera; Sun, Tianliang; Annunziato, Stefano; Lachal, Julie; Redmond, Emily; Wang, Louis; Wetzel, Kristie; Capodieci, Paola; Turner, Jonathan; Schutzius, Gabi; Unterreiner, Vincent; Trunzer, Markus; Buschmann, Nicole; Behnke, Dirk; Machauer, Rainer; Scheufler, Clemens; Parker, Christian N.; Ferro, Magali; Grevot, Armelle; Beyerbach, Armin; Lu, Wei-Yu; Forbes, Stuart J.; Wagner, Jueurorgen; Bouwmeester, Tewis; Liu, Jun; Sohal, Bindi; Sahambi, Sukhdeep; Greenbaum, Linda E.; Lohmann, Felix; Hoppe, Philipp; Cong, Feng; Sailer, Andreas W.; Ruffner, Heinz; Glatthar, Ralf; Humar, Bostjan; Clavien, Pierre-Alain; Dill, Michael T.; George, Elizabeth; Maibaum, Jueurorgen; Liberali, Prisca; Tchorz, Jan S. 分享 收藏
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ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation ZNRF3和RNF43协同保护代谢肝分区和肝细胞增殖 Sun, Tianliang; Annunziato, Stefano; Bergling, Sebastian; Sheng, Caibin; Orsini, Vanessa; Forcella, Pascal; Pikiolek, Monika; Kancherla, Venkatesh; Holwerda, Sjoerd; Imanci, Dilek; Wu, Fabian; Meylan, Ludivine Challet; Puehringer, Lea F.; Waldt, Annick; Oertli, Mevion; Schuierer, Sven; Terracciano, Luigi M.; Reinker, Stefan; Ruffner, Heinz; Bouwmeester, Tewis; Sailer, Andreas W.; George, Elizabeth; Roma, Guglielmo; de Weck, Antoine; Piscuoglio, Salvatore; Lohmann, Felix; Naumann, Ulrike; Liberali, Prisca; Cong, Feng; Tchorz, Jan S. 分享 收藏
BET bromodomain inhibitors regulate keratinocyte plasticity Schutzius, Gabi; Kolter, Christian; Bergling, Sebastian; Tortelli, Federico; Fuchs, Florian; Renner, Steffen; Guagnano, Vito; Cotesta, Simona; Rueeger, Heinrich; Faller, Michael; Bouchez, Laure; Salathe, Adrian; Nigsch, Florian; Richards, Shola M.; Louis, Malvina; Gruber, Viktoria; Aebi, Alexandra; Turner, Jonathan; Grandjean, Frederic; Li, Jun; Dimitri, Chris; Thomas, Jason R.; Schirle, Markus; Blank, Jutta; Drueckes, Peter; Vaupel, Andrea; Tiedt, Ralph; Manley, Paul W.; Klopp, Julia; Hemmig, Rene; Zink, Florence; Leroy, Nelly; Carbone, Walter; Roma, Guglielmo; Keller, Caroline Gubser; Dales, Natalie; Beyerbach, Armin; Zimmerlin, Alfred; Bonenfant, Debora; Terranova, Remi; Berwick, Amy; Sahambi, Sukhdeep; Reynolds, Aimee; Jennings, Lori L.; Ruffner, Heinz; Tarsa, Peter; Bouwmeester, Tewis; Driver, Vickie; Frederiksen, Mathias; Lohmann, Felix; Kirkland, Susan 分享 收藏
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AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration Sun, Tianliang; Pikiolek, Monika; Orsini, Vanessa; Bergling, Sebastian; Holwerda, Sjoerd; Morelli, Lapo; Hoppe, Philipp S.; Planas-Paz, Lara; Yang, Yi; Ruffner, Heinz; Bouwmeester, Tewis; Lohmann, Felix; Terracciano, Luigi M.; Roma, Guglielmo; Cong, Feng; Tchorz, Jan S. 分享 收藏
IRF2 is a master regulator of human keratinocyte stem cell fate Mercado, Nicolas; Schutzius, Gabi; Kolter, Christian; Estoppey, David; Bergling, Sebastian; Roma, Guglielmo; Keller, Caroline Gubser; Nigsch, Florian; Salathe, Adrian; Terranova, Remi; Reece-Hoyes, John; Alford, John; Russ, Carsten; Knehr, Judith; Hoepfner, Dominic; Aebi, Alexandra; Ruffner, Heinz; Beck, Tanner C.; Jagannathan, Sajjeev; Olson, Calla M.; Sheppard, Hadley E.; Elsarrag, Selma Z.; Bouwmeester, Tewis; Frederiksen, Mathias; Lohmann, Felix; Lin, Charles Y.; Kirkland, Susan 分享 收藏
Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation Rabl, Julius; Bunker, Richard D.; Schenk, Andreas D.; Cavadini, Simone; Gill, Mark E.; Abdulrahman, Wassim; Andres-Pons, Amparo; Luijsterburg, Martijn S.; Ibrahim, Adel F. M.; Branigan, Emma; Aguirre, Jacob D.; Marceau, Aimee H.; Guerillon, Claire; Bouwmeester, Tewis; Hassiepen, Ulrich; Peters, Antoine H. F. M.; Renatus, Martin; Gelman, Laurent; Rubin, Seth M.; Mailand, Niels; van Attikum, Haico; Hay, Ronald T.; Thomae, Nicolas H. 分享 收藏
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury Planas-Paz, Lara; Sun, Tianliang; Pikiolek, Monika; Cochran, Nadire R.; Bergling, Sebastian; Orsini, Vanessa; Yang, Zinger; Sigoillot, Frederic; Jetzer, Jasna; Syed, Maryam; Neri, Marilisa; Schuierer, Sven; Morelli, Lapo; Hoppe, Philipp S.; Schwarzer, Wibke; Cobos, Carlos M.; Alford, John L.; Zhang, Le; Cuttat, Rachel; Waldt, Annick; Carballido-Perrig, Nicole; Nigsch, Florian; Kinzel, Bernd; Nicholson, Thomas B.; Yang, Yi; Mao, Xiaohong; Terracciano, Luigi M.; Russ, Carsten; Reece-Hoyes, John S.; Keller, Caroline Gubser; Sailer, Andreas W.; Bouwmeester, Tewis; Greenbaum, Linda E.; Lugus, Jesse J.; Cong, Feng; McAllister, Gregory; Hoffman, Gregory R.; Roma, Guglielmo; Tchorz, Jan S. 分享 收藏
Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy Bertschi, Nicole L.; Voorberg-van der Wel, Annemarie; Zeeman, Anne-Marie; Schuierer, Sven; Nigsch, Florian; Carbone, Walter; Knehr, Judith; Gupta, Devendra K.; Hofman, Sam O.; van der Werff, Nicole; Nieuwenhuis, Ivonne; Klooster, Els; Faber, Bart W.; Flannery, Erika L.; Mikolajczak, Sebastian A.; Chuenchob, Vorada; Shrestha, Binesh; Beibel, Martin; Bouwmeester, Tewis; Kangwanrangsan, Niwat; Sattabongkot, Jetsumon; Diagana, Thierry T.; Kocken, Clemens H. M.; Roma, Guglielmo 分享 收藏
Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells. Calabrese, D.; Roma, G.; Bergling, S.; Carbone, W.; Mele, V.; Nuciforo, S.; Fofana, I.; Campana, B.; Szkolnicka, D.; Hay, D.; Tchorz, J.; Bouwmeester, T.; Wieland, S.; Heim, M. 分享 收藏
A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi Voorberg-van der Wel, Annemarie; Roma, Guglielmo; Gupta, Devendra Kumar; Schuierer, Sven; Nigsch, Florian; Carbone, Walter; Zeeman, Anne-Marie; Lee, Boon Heng; Hofman, Sam O.; Faber, Bart W.; Knehr, Judith; Pasini, Erica; Kinzel, Bernd; Bifani, Pablo; Bonamy, Ghislain M. C.; Bouwmeester, Tewis; Kocken, Clemens H. M.; Diagna, Thierry Tidiane 分享 收藏
A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia Suply, Thomas; Hannedouche, Sebastien; Carte, Nathalie; Li, Jianping; Grosshans, Bianka; Schaefer, Michael; Raad, Layla; Beck, Valerie; Vidal, Solange; Hiou-Feige, Agnes; Beluch, Noemie; Barbieri, Samuel; Wirsching, Johann; Lageyre, Nadine; Hillger, Frank; Debon, Corinne; Dawson, Janet; Smith, Philip; Lannoy, Vincent; Detheux, Michel; Bitsch, Francis; Falchetto, Rocco; Bouwmeester, Tewis; Porter, Jeffrey; Baumgarten, Birgit; Mansfield, Keith; Carballido, Jose M.; Seuwen, Klaus; Bassilana, Frederic 分享 收藏
The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase Estoppey, David; Lee, Chia Min; Janoschke, Marco; Lee, Boon Heng; Wan, Kah Fei; Dong, Hongping; Mathys, Philippe; Filipuzzi, Ireos; Schuhmann, Tim; Riedl, Ralph; Aust, Thomas; Galuba, Olaf; McAllister, Gregory; Russ, Carsten; Spiess, Martin; Bouwmeester, Tewis; Bonamy, Ghislain M. C.; Hoepfner, Dominic 分享 收藏
Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells Estoppey, David; Hewett, Jeffrey W.; Guy, Chantale T.; Harrington, Edmund; Thomas, Jason R.; Schirle, Markus; Cuttat, Rachel; Waldt, Annick; Gerrits, Bertran; Yang, Zinger; Schuierer, Sven; Pan, Xuewen; Xie, Kevin; Carbone, Walter; Knehr, Judith; Lindeman, Alicia; Russ, Carsten; Frias, Elizabeth; Hoffman, Gregory R.; Varadarajan, Malini; Ramadan, Nadire; Reece-Hoyes, John S.; Wang, Qiong; Chen, Xin; McAllister, Gregory; Roma, Guglielmo; Bouwmeester, Tewis; Hoepfner, Dominic 分享 收藏
CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations Brykczynska, Urszula; Pecho-Vrieseling, Eline; Thiemeyer, Anke; Klein, Jessica; Fruh, Isabelle; Doll, Thierry; Manneville, Carole; Fuchs, Sascha; Iazeolla, Mariavittoria; Beibel, Martin; Roma, Guglielmo; Naumann, Ulrike; Kelley, Nicholas; Oakeley, Edward J.; Mueller, Matthias; Gomez-Mancilla, Baltazar; Buhler, Marc; Tabolacci, Elisabetta; Chiurazzi, Pietro; Neri, Giovanni; Bouwmeester, Tewis; Di Giorgio, Francesco Paolo; Fodor, Barna D. 分享 收藏
The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size (vol 18, pg 467, 2016) Planas-Paz, Lara; Orsini, Vanessa; Boulter, Luke; Calabrese, Diego; Pikiolek, Monika; Nigsch, Florian; Xie, Yang; Roma, Guglielmo; Donovan, Adriana; Marti, Patricia; Beckmann, Nicolau; Dill, Michael T.; Carbone, Walter; Bergling, Sebastian; Isken, Andrea; Mueller, Matthias; Kinzel, Bernd; Yang, Yi; Mao, Xiaohong; Nicholson, Thomas B.; Zamponi, Raffaella; Capodieci, Paola; Valdez, Reginald; Rivera, Daniel; Loew, Andreas; Ukomadu, Chinweike; Terracciano, Luigi M.; Bouwmeester, Tewis; Cong, Feng; Heim, Markus H.; Forbes, Stuart J.; Ruffner, Heinz; Tchorz, Jan S. 分享 收藏
Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening 通过全基因组CRISPR-Cas9缺失筛查鉴定致癌驱动突变 Kiessling, Michael K.; Schuierer, Sven; Stertz, Silke; Beibel, Martin; Bergling, Sebastian; Knehr, Judith; Carbone, Walter; de Valliere, Cheryl; Tchinda, Joelle; Bouwmeester, Tewis; Seuwen, Klaus; Rogler, Gerhard; Roma, Guglielmo 分享 收藏
MiR-210 promotes sensory hair cell formation in the organ of corti Riccardi, Sabrina; Bergling, Sebastian; Sigoillot, Frederic; Beibel, Martin; Werner, Annick; Leighton-Davies, Juliet; Knehr, Judith; Bouwmeester, Tewis; Parker, Christian N.; Roma, Guglielmo; Kinzel, Bernd 分享 收藏
The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size RSPO-LGR4/5-ZNRF3/RNF43模块控制肝脏分区和大小 Planas-Paz, Lara; Orsini, Vanessa; Boulter, Luke; Calabrese, Diego; Pikiolek, Monika; Nigsch, Florian; Xie, Yang; Roma, Guglielmo; Donovan, Adriana; Marti, Patricia; Beckmann, Nicolau; Dill, Michael T.; Carbone, Walter; Bergling, Sebastian; Isken, Andrea; Mueller, Matthias; Kinzel, Bernd; Yang, Yi; Mao, Xiaohong; Nicholson, Thomas B.; Zamponi, Raffaella; Capodieci, Paola; Valdez, Reginald; Rivera, Daniel; Loew, Andreas; Ukomadu, Chinweike; Terracciano, Luigi M.; Bouwmeester, Tewis; Cong, Feng; Heim, Markus H.; Forbes, Stuart J.; Ruffner, Heinz; Tchorz, Jan S. 分享 收藏
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