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H

Heikki Ruskoaho

University of Helsinki

63H指数
413论文数
1.5W被引数
收录论文 132
发表时间
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Genotype-Dependent Effects of Mechanical Stretch and GATA4-Targeted Compound 3i-1262 in Cardiomyopathy Patient–Derived hiPSC-Cardiomyocytes机械拉伸和GATA4靶向化合物3i-1262在心肌病患者的hiPSC-心肌细胞中的基因型依赖效应
errBASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
IF3.3
err2026-09-09
err0
errOAAI
errSaana Pohjavaara; Sini M. Kinnunen; Heikki Ruskoaho; Katriina Aalto-Setälä; Mika J. Välimäki; Virpi Talman
err分享
err收藏
GATA4-targeted compounds induce apoptosis and diminish viability of hepatoblastoma cellsGATA4靶向化合物诱导肝母细胞瘤细胞凋亡并降低其存活率
errPLoS One
IF2.6
err2026-02-11
err0
PREAI
errKinnunen, Sini M.; Eloranta, Katja; Pihlajoki, Marjut; Valimaki, Mika J.; Pohjavaara, Saana; Indersie, Emilie; Cairo, Stefano; Kuusinen, Aarni; Ruskoaho, Heikki; Heikinheimo, Markku
err分享
err收藏
Development and comparison of single FLT3-inhibitors to dual FLT3/TAF1-inhibitors as an anti-leukemic approach单FLT3抑制剂与双FLT3/TAF1抑制剂的研发与比较：作为一种抗白血病方法
errPLOS ONE
IF2.6
err2025-03-28
err0
errOAAI
errLeigh, Robert S.; Kaynak, Bogac L.; Ruskoaho, Heikki; Valimaki, Mika J.
err分享
err收藏
Characterisation of the novel SCN5A-P1891A variant, implicated in left ventricular noncompaction cardiomyopathy in a Finnish family, using human induced pluripotent stem cell-derived cardiomyocytes
errEUROPEAN HEART JOURNAL
IF35.6
err2024-10-28
err0
PREAI
errMajid, Q. A.; Prajapati, C.; Liu, X.; Kari-Koskinen, J.; Pohjolainen, L.; Karhu, S. T.; Ruskoaho, H.; Varjosalo, M.; Aalto-Setala, K.; Talman, V
err分享
err收藏
Affinity chromatography reveals direct binding of the GATA4-NKX2-5 interaction inhibitor (3i-1000) with GATA4
errSCIENTIFIC REPORTS
IF3.9
err2024-04-18
err0
errOAAI
errJumppanen, Mikael; Kinnunen, Sini M.; Zore, Matej; Valimaki, Mika J.; Talman, Virpi; Gennas, Gustav Boije af; Ruskoaho, Heikki J.; Yli-Kauhaluoma, Jari
err分享
err收藏
α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptor
errEMBO REPORTS
IF6.2
err2024-03-07
err1
errOAAI
errSuominen, Anni; Saldo Rubio, Guillem; Ruohonen, Saku; Szabo, Zoltan; Pohjolainen, Lotta; Ghimire, Bishwa; Ruohonen, Suvi; Saukkonen, Karla; Ijas, Jani; Skarp, Sini; Kaikkonen, Leena; Cai, Minying; Wardlaw, Sharon; Ruskoaho, Heikki; Talman, Virpi; Savontaus, Eriika; Kerkelae, Risto; Rinne, Petteri
err分享
err收藏
Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compound
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2024-01-02
err0
errOAAI
errPohjolainen, Lotta; Kinnunen, Sini M.; Auno, Samuli; Kiriazis, Alexandros; Pohjavaara, Saana; Kari-Koskinen, Julia; Zore, Matej; Jumppanen, Mikael; Yli-Kauhaluoma, Jari; Talman, Virpi; Ruskoaho, Heikki; Valimaki, Mika J.
err分享
err收藏
Macrophage Hitchhiking Nanoparticles for the Treatment of Myocardial Infarction: An In Vitro and In Vivo Study巨噬细胞搭便车纳米粒治疗心肌梗死的体内外研究
errADVANCED FUNCTIONAL MATERIALS
IF19
err2023-05-19
err4
errOAAI
errTorrieri, Giulia; Iqbal, Imran; Fontana, Flavia; Talman, Virpi; Liljenback, Heidi; Putri, Andriana; Nammas, Wail; Rajander, Johan; Guo-Li, Xiang; Low, Philip S. S.; Teesalu, Tambet; Roivainen, Anne; Hirvonen, Jouni; Ruskoaho, Heikki; Balasubramanian, Vimalkumar; Saraste, Antti; Santos, Helder A.
err分享
err收藏
In vitro Evaluation of the Therapeutic Effects of Dual-Drug Loaded Spermine-Acetalated Dextran Nanoparticles Coated with Tannic Acid for Cardiac Applications单宁酸包被的双载药精胺-缩醛化葡聚糖纳米颗粒对心脏应用的治疗效果的体外评价
errADVANCED FUNCTIONAL MATERIALS
IF19
err2021-10-22
err19
errOAAI
errTorrieri, Giulia; Ferreira, Monica P. A.; Shahbazi, Mohammad-Ali; Talman, Virpi; Karhu, S. Tuuli; Pohjolainen, Lotta; Carvalho, Claudia; Pinto, Joao F.; Hirvonen, Jouni; Ruskoaho, Heikki; Balasubramanian, Vimalkumar; Santos, Helder A.
err分享
err收藏
Domain-Independent Inhibition of CBP/p300 Attenuates α-Synuclein Aggregation
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-06-10
err6
errOAAI
errHlushchuk, Irena; Ruskoaho, Heikki; Domanskyi, Andrii; Airavaara, Mikko; Valimaki, Mika J.
err分享
err收藏
GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2021-03-18
err9
errOAAI
errValimaki, Mika J.; Leigh, Robert S.; Kinnunen, Sini M.; March, Alexander R.; de Sande, Ana Hernandez; Kinnunen, Matias; Varjosalo, Markku; Heinaniemi, Merja; Kaynak, Bogac L.; Ruskoaho, Heikki
err分享
err收藏
Distinct Regulation of Cardiac Fibroblast Proliferation and Transdifferentiation by Classical and Novel Protein Kinase C Isoforms: Possible Implications for New Antifibrotic Therapies
errMOLECULAR PHARMACOLOGY
IF3
err2021-02-01
err10
errOAAI
errKarhu, S. Tuuli; Ruskoaho, Heikki; Talman, Virpi
err分享
err收藏
Tannic Acid Coated Nanoparticles for Cardiac Regeneration
errCIRCULATION RESEARCH
IF16.2
err2020-07-31
err1
PREAI
errTorrieri, Giulia; Ferreira, Monica P.; Shahbazi, Mohammad-Ali; Talman, Virpi; Carvalho, Claudia; Karhu, Tuuli; Pinto, Joao F.; Hirvonen, Jouni; Ruskoaho, Heikki J.; Balasubramanian, Vimalkumar; Santos, Helder A.
err分享
err收藏
Multifunctional 3D-Printed Patches for Long-Term Drug Release Therapies after Myocardial Infarction
errADVANCED FUNCTIONAL MATERIALS
IF19
err2020-07-01
err79
errOAAI
errAjdary, Rubina; Ezazi, Nazanin Zanjanizadeh; Correia, Alexandra; Kemell, Marianna; Huan, Siqi; Ruskoaho, Heikki J.; Hirvonen, Jouni; Santos, Helder A.; Rojas, Orlando J.
err分享
err收藏
Circulating protein biomarkers predict incident hypertensive heart failure independently of N-terminal pro-B-type natriuretic peptide levels循环蛋白质生物标志物可独立于N末端b型利钠肽前体水平预测高血压性心力衰竭的发生
errESC HEART FAILURE
IF3.7
err2020-05-14
err12
errOAAI
errFernandez, Celine; Rysa, Jaana; Strom, Kristoffer; Nilsson, Jan; Engstrom, Gunnar; Orho-Melander, Marju; Ruskoaho, Heikki; Melander, Olle
err分享
err收藏
GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytesGATA4-targeted化合物在体外和体内对阿霉素诱导的毒性具有心脏保护作用: 使用人iPSC衍生的心肌细胞建立慢性心脏毒性模型
errARCHIVES OF TOXICOLOGY
IF6.9
err2020-03-17
err17
errOAAI
errKarhu, S. Tuuli; Kinnunen, Sini M.; Tolli, Marja; Valimaki, Mika J.; Szabo, Zoltan; Talman, Virpi; Ruskoaho, Heikki
err分享
err收藏
Fabrication and Characterization of Drug-Loaded Conductive Poly(glycerol sebacate)/Nanoparticle-Based Composite Patch for Myocardial Infarction Applications
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2020-01-22
err62
errOAAI
errEzazi, Nazanin Zanjanizadeh; Ajdary, Rubina; Correia, Alexandra; Makila, Ermei; Salonen, Jamb; Kemell, Marianna; Hirvonen, Jouni; Rojas, Orlando J.; Ruskoaho, Heikki J.; Santos, Helder A.
err分享
err收藏
Dual-peptide functionalized acetalated dextran-based nanoparticles for sequential targeting of macrophages during myocardial infarction
errNANOSCALE
IF5.1
err2020-01-01
err47
errOAAI
errTorrieri, Giulia; Fontana, Flavia; Figueiredo, Patricia; Liu, Zehua; Ferreira, Monica P. A.; Talman, Virpi; Martins, Joao P.; Fusciello, Manlio; Moslova, Karina; Teesalu, Tambet; Cerullo, Vincenzo; Hirvonen, Jouni; Ruskoaho, Heikki; Balasubramanian, Vimalkumar; Santos, Helder A.
err分享
err收藏
A novel dual reporter embryonic stem cell line for toxicological assessment of teratogen-induced perturbation of anterior-posterior patterning of the heart
errARCHIVES OF TOXICOLOGY
IF6.9
err2019-12-06
err7
errOAAI
errLeigh, Robert S.; Ruskoaho, Heikki J.; Kaynak, Bogac L.
err分享
err收藏
Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction Modulators
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2019-08-20
err16
errOAAI
errJumppanen, Mikael; Kinnunen, Sini M.; Valimaki, Mika J.; Talman, Virpi; Auno, Samuli; Bruun, Tanja; af Gennas, Gustav Boije; Xhaard, Henri; Aumuller, Ingo B.; Ruskoaho, Heikki; Yli-Kauhaluoma, Jari
err分享
err收藏

研究方向

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合作学者
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H 指数: 131 · 论文数: 1.6K
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H 指数: 123 · 论文数: 674
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