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Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence Willoughby, Jennifer L. S.; George, Kelly; Roberto, Mark P.; Chin, Hang Gyeong; Stoiber, Patrick; Shin, Hyunjin; Pedamallu, Chandra Sekhar; Schaus, Scott E.; Fitzgerald, Kevin; Shah, Jagesh; Hansen, Ulla 分享 收藏
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (vol 24, pg 679, 2018) 弥漫性大b细胞淋巴瘤的分子亚型与不同的致病机制和结果相关 (第24卷，679页，2018) Chapuy, Bjoern; Stewart, Chip; Dunford, Andrew J.; Kim, Jaegil; Kamburov, Atanas; Redd, Robert A.; Lawrence, Mike S.; Roemer, Margaretha G. M.; Li, Amy J.; Ziepert, Marita; Staiger, Annette M.; Wala, Jeremiah A.; Ducar, Matthew D.; Leshchiner, Ignaty; Rheinbay, Ester; Taylor-Weiner, Amaro; Coughlin, Caroline A.; Hess, Julian M.; Pedamallu, Chandra S.; Livitz, Dimitri; Rosebrock, Daniel; Rosenberg, Mara; Tracy, Adam A.; Horn, Heike; van Hummelen, Paul; Feldman, Andrew L.; Link, Brian K.; Novak, Anne J.; Cerhan, James R.; Habermann, Thomas M.; Siebert, Reiner; Rosenwald, Andreas; Thorner, Aaron R.; Meyerson, Matthew L.; Golub, Todd R.; Beroukhim, Rameen; Wulf, Gerald G.; Ott, German; Rodig, Scott J.; Monti, Stefano; Neuberg, Donna S.; Loeffler, Markus; Pfreundschuh, Michael; Trumper, Lorenz; Getz, Gad; Shipp, Margaret A. 分享 收藏
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes (vol 24, pg 679, 2018) 弥漫性大b细胞淋巴瘤的分子亚型与不同的致病机制和结果相关 (第24卷，679页，2018) Chapuy, Bjoern; Stewart, Chip; Dunford, Andrew J.; Kim, Jaegil; Kamburov, Atanas; Redd, Robert A.; Lawrence, Mike S.; Roemer, Margaretha G. M.; Li, Amy J.; Ziepert, Marita; Staiger, Annette M.; Wala, Jeremiah A.; Ducar, Matthew D.; Leshchiner, Ignaty; Rheinbay, Ester; Taylor-Weiner, Amaro; Coughlin, Caroline A.; Hess, Julian M.; Pedamallu, Chandra S.; Livitz, Dimitri; Rosebrock, Daniel; Rosenberg, Mara; Tracy, Adam A.; Horn, Heike; van Hummelen, Paul; Feldman, Andrew L.; Link, Brian K.; Novak, Anne J.; Cerhan, James R.; Habermann, Thomas M.; Siebert, Reiner; Rosenwald, Andreas; Thorner, Aaron R.; Meyerson, Matthew L.; Golub, Todd R.; Beroukhim, Rameen; Wulf, Gerald G.; Ott, German; Rodig, Scott J.; Monti, Stefano; Neuberg, Donna S.; Loeffler, Markus; Pfreundschuh, Michael; Trumper, Lorenz; Getz, Gad; Shipp, Margaret A. 分享 收藏
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes 弥漫性大b细胞淋巴瘤的分子亚型与不同的致病机制和结果相关 Chapuy, Bjoern; Stewart, Chip; Dunford, Andrew J.; Kim, Jaegil; Kamburov, Atanas; Redd, Robert A.; Lawrence, Mike S.; Roemer, Margaretha G. M.; Li, Amy J.; Ziepert, Marita; Staiger, Annette M.; Wala, Jeremiah A.; Ducar, Matthew D.; Leshchiner, Ignaty; Rheinbay, Ester; Taylor-Weiner, Amaro; Coughlin, Caroline A.; Hess, Julian M.; Pedamallu, Chandra S.; Livitz, Dimitri; Rosebrock, Daniel; Rosenberg, Mara; Tracy, Adam A.; Horn, Heike; van Hummelen, Paul; Feldman, Andrew L.; Link, Brian K.; Novak, Anne J.; Cerhan, James R.; Habermann, Thomas M.; Siebert, Reiner; Rosenwald, Andreas; Thorner, Aaron R.; Meyerson, Matthew L.; Golub, Todd R.; Beroukhim, Rameen; Wulf, Gerald G.; Ott, German; Rodig, Scott J.; Monti, Stefano; Neuberg, Donna S.; Loeffler, Markus; Pfreundschuh, Michael; Truemper, Lorenz; Getz, Gad; Shipp, Margaret A. 分享 收藏
Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants Amin, Samirkumar; Awadalla, Philip; Biankin, Andrew; Boutros, Paul; Brazma, Alvis; Brooks, Angela Norie; Calabrese, Claudia; Chang, David; Chateigner, Aurelien; Chen, Ken; Chong, Zechen; Craft, Brian; Creighton, Chad; Demircioglu, Deniz; Fonseca, Nuno; Frenkel-Morgenstern, Milana; Getz, Gad; Goke, Jonathan; Goldman, Mary; Greger, Liliana; Haider, Syed; He, Yao; Hoadley, Katherine; Ji, Yuan; Kahles, Andre; Khurana, Ekta; Korbel, Jan; Lehmann, Kjong; Liang, Han; Liu, Fenglin; Marin, Maximillian; Meyerson, Matthew; Ojesina, Akinyemi; Ouellette, Francis; Pedamallu, Chandra; Perry, Marc; Ratsch, Gunnar; Schwarz, Roland; Shiraishi, Yuichi; Soulette, Cameron; Stegle, Oliver; Tan, Patrick; Valencia, Alfonso; Xiang, Linda; Yung, Christina; Zhang, Junjun; Zhang, Fan; Zhang, Zemin; Zhu, Jingchun 分享 收藏
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (vol 18, pg 2780, 2017) Farshidfar, Farshad; Zheng, Siyuan; Gingras, Marie-Claude; Newton, Yulia; Shih, Juliann; Robertson, A. Gordon; Hinoue, Toshinori; Hoadley, Katherine A.; Gibb, Ewan A.; Roszik, Jason; Covington, Kyle R.; Wu, Chia-Chin; Shinbrot, Eve; Stransky, Nicolas; Hegde, Apurva; Yang, Ju Dong; Reznik, Ed; Sadeghi, Sara; Pedamallu, Chandra Sekhar; Ojesina, Akinyemi I.; Hess, Julian M.; Auman, J. Todd; Rhie, Suhn K.; Bowlby, Reanne; Borad, Mitesh J.; Zhu, Andrew X.; Stuart, Josh M.; Sander, Chris; Akbani, Rehan; Cherniack, Andrew D.; Deshpande, Vikram; Mounajjed, Taofic; Foo, Wai Chin; Torbenson, Michael S.; Kleiner, David E.; Laird, Peter W.; Wheeler, David A.; McRee, Autumn J.; Bathe, Oliver F.; Andersen, Jesper B.; Bardeesy, Nabeel; Roberts, Lewis R.; Kwong, Lawrence N. 分享 收藏
Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma Kwong, Lawrence N.; Zou, Lihua; Chagani, Sharmeen; Pedamallu, Chandra Sekhar; Liu, Mingguang; Jiang, Shan; Protopopov, Alexei; Zhang, Jianhua; Getz, Gad; Chin, Lynda 分享 收藏
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles Farshidfar, Farshad; Zheng, Siyuan; Gingras, Marie-Claude; Newton, Yulia; Shih, Juliann; Robertson, A. Gordon; Hinoue, Toshinori; Hoadley, Katherine A.; Gibb, Ewan A.; Roszik, Jason; Covington, Kyle R.; Wu, Chia-Chin; Shinbrot, Eve; Stransky, Nicolas; Hegde, Apurva; Yang, Ju Dong; Reznik, Ed; Sadeghi, Sara; Pedamallu, Chandra Sekhar; Ojesina, Akinyemi I.; Hess, Julian M.; Auman, J. Todd; Rhie, Suhn K.; Bowlby, Reanne; Borad, Mitesh J.; Zhu, Andrew X.; Stuart, Josh M.; Sander, Chris; Akbani, Rehan; Cherniack, Andrew D.; Deshpande, Vikram; Mounajjed, Taofic; Foo, Wai Chin; Torbenson, Michael S.; Kleiner, David E.; Laird, Peter W.; Wheeler, David A.; Mcree, Autumn J.; Bathe, Oliver F.; Andersen, Jesper B.; Bardeesy, Nabeel; Roberts, Lewis R.; Kwong, Lawrence N. 分享 收藏
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Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas 肺腺癌和鳞状细胞癌中体细胞基因组改变的不同模式 Campbell, Joshua D.; Alexandrov, Anton; Kim, Jaegil; Wala, Jeremiah; Berger, Alice H.; Pedamallu, Chandra Sekhar; Shukla, Sachet A.; Guo, Guangwu; Brooks, Angela N.; Murray, Bradley A.; Imielinski, Marcin; Hu, Xin; Ling, Shiyun; Akbani, Rehan; Rosenberg, Mara; Cibulskis, Carrie; Ramachandran, Aruna; Collisson, Eric A.; Kwiatkowski, David J.; Lawrence, Michael S.; Weinstein, John N.; Verhaak, Roel G. W.; Wu, Catherine J.; Hammerman, Peter S.; Cherniack, Andrew D.; Getz, Gad; Artyomov, Maxim N.; Schreiber, Robert; Govindan, Ramaswamy; Meyerson, Matthew 分享 收藏
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Validation and calibration of next-generation sequencing to identify Epstein-Barr Virus-positive gastric cancer Camargo, M. Constanza; Bowlby, Reanne; Chu, Andy; Pedamallu, Chandra S.; Thorsson, Vesteinn; Elmore, Sandra; Mungall, Andrew; Bass, Adam; Gulley, Margaret L.; Rabkin, Charles S. 分享 收藏
Validation and calibration of next-generation sequencing to identify Epstein-Barr virus-positive gastric cancer in The Cancer Genome Atlas Camargo, M. Constanza; Bowlby, Reanne; Chu, Andy; Pedamallu, Chandra Sekhar; Thorsson, Vesteinn; Elmore, Sandra; Mungall, Andrew J.; Bass, Adam J.; Gulley, Margaret L.; Rabkin, Charles S. 分享 收藏
Dynamic Epigenetic Regulation by Menin During Pancreatic Islet Tumor Formation Lin, Wenchu; Watanabe, Hideo; Peng, Shouyong; Francis, Joshua M.; Kaplan, Nathan; Pedamallu, Chandra Sekhar; Ramachandran, Aruna; Agoston, Agoston; Bass, Adam J.; Meyerson, Matthew 分享 收藏
DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors 转移性尿路上皮癌DNA拷贝数分析与原发肿瘤比较 Bambury, Richard M.; Bhatt, Ami S.; Riester, Markus; Pedamallu, Chandra Sekhar; Duke, Fujiko; Bellmunt, Joaquim; Stack, Edward C.; Werner, Lillian; Park, Rachel; Iyer, Gopa; Loda, Massimo; Kantoff, Philip W.; Michor, Franziska; Meyerson, Matthew; Rosenberg, Jonathan E. 分享 收藏
Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women Chung, Tony K. H.; Van Hummelen, Paul; Chan, Paul K. S.; Cheung, Tak Hong; Yim, So Fan; Yu, Mei Y.; Ducar, Matthew D.; Thorner, Aaron R.; MacConaill, Laura E.; Doran, Graeme; Pedamallu, Chandra Sekhar; Ojesina, Akinyemi I.; Wong, Raymond R. Y.; Wang, Vivian W.; Freeman, Samuel S.; Lau, Tat San; Kwong, Joseph; Chan, Loucia K. Y.; Fromer, Menachem; May, Taymaa; Worley, Michael J., Jr.; Esselen, Katharine M.; Elias, Kevin M.; Lawrence, Michael; Getz, Gad; Smith, David I.; Crum, Christopher P.; Meyerson, Matthew; Berkowitz, Ross S.; Wong, Yick Fu 分享 收藏
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma 互补的基因组方法强调PI3K/mTOR途径是骨肉瘤的常见脆弱性 Perry, Jennifer A.; Kiezun, Adam; Tonzi, Peter; Van Allen, Eliezer M.; Carter, Scott L.; Baca, Sylvan C.; Cowley, Glenn S.; Bhatt, Ami S.; Rheinbay, Esther; Pedamallu, Chandra Sekhar; Helman, Elena; Taylor-Weiner, Amaro; McKenna, Aaron; DeLuca, David S.; Lawrence, Michael S.; Ambrogio, Lauren; Sougnez, Carrie; Sivachenko, Andrey; Walensky, Loren D.; Wagle, Nikhil; Mora, Jaume; de Torres, Carmen; Lavarino, Cinzia; Aguiar, Simone Dos Santos; Yunes, Jose Andres; Brandalise, Silvia Regina; Mercado-Celis, Gabriela Elisa; Melendez-Zajgla, Jorge; Cardenas-Cardos, Roco; Velasco-Hidalgo, Liliana; Roberts, Charles W. M.; Garraway, Levi A.; Rodriguez-Galindo, Carlos; Gabriel, Stacey B.; Lander, Eric S.; Golub, Todd R.; Orkin, Stuart H.; Getz, Gad; Janeway, Katherine A. 分享 收藏
Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer Ojesina, Akinyemi I.; Murray, Bradley; Bjorge, Line; Woie, Kathrine; Krakstad, Camilla; Lichtenstein, Lee; Pedamallu, Chandra Sekhar; Taylor-Weiner, Amaro; Freeman, Samuel S.; Cherniack, Andrew D.; Lawrence, Michael S.; Cibulskis, Kristian; Carter, Scott L.; Walline, Heather; Carey, Thomas E.; Vintermyr, Olav K.; Bertelsen, Bjorn; Crum, Christopher P.; Getz, Gad; Meyerson, Matthew; Salvesen, Helga B. 分享 收藏
SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas Watanabe, Hideo; Ma, Qiuping; Peng, Shouyong; Adelmant, Guillaume; Swain, Danielle; Song, Wenyu; Fox, Cameron; Francis, Joshua M.; Pedamallu, Chandra Sekhar; Deluca, David S.; Brooks, Angela N.; Que, Jianwen; Rustgi, Anil K.; Wong, Kwok-kin; Ligon, Keith L.; Liu, X. Shirley; Marto, Jarrod A.; Meyerson, Matthew; Bass, Adam J. 分享 收藏
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