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Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease BAG3介导的BACE1稳定性的破坏可以减轻阿尔茨海默病小鼠模型中的神经病理学和记忆缺陷。 Xia, Lei; Li, Junjie; Pang, Yayan; Dai, Chunfang; Xu, Mingliang; Du, Yehong; Tian, Qiuyun; Yi, Lilin; Wu, Bin; Chen, Mulan; Qiu, Yiqiong; Cheng, Chongjie; Wang, Yu Tian; Song, Weihong 分享 收藏
ELK1 inhibition alleviates amyloid pathology and memory decline by promoting the SYVN1-mediated ubiquitination and degradation of PS1 in Alzheimer's disease ELK1抑制通过促进SYVN1介导的PS1泛素化和降解，缓解阿尔茨海默病中的淀粉样蛋白病理和记忆衰退。 Yi, Lilin; Li, Junjie; He, Yan; Wang, Jiaojiao; Wang, Maoju; Guo, Song; Luo, Man; Wu, Bin; Xu, Mingliang; Tian, Qiuyun; Fan, Yepeng; Chen, Mulan; Xu, Boqing; Xia, Lei; Song, Weihong; He, Guiqiong; Du, Yehong; Dong, Zhifang 分享 收藏
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Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice Zhu, Haixia; Wang, Hongxiang; Wang, Dan; Liu, Shuqiao; Sun, Xiaoli; Qu, Zhengjiang; Zhang, Aizhen; Ye, Chao; Li, Runze; Wu, Bin; Liu, Min; Gao, Jiangang 分享 收藏
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Balanced Solution Versus Normal Saline in Predicted Severe Acute Pancreatitis A Stepped Wedge Cluster Randomized Trial Ke, Lu; Ye, Bo; Huang, Mingfeng; Chen, Tao; Doig, Gordon; Li, Chao; Chen, Yingjie; Zhang, Hongwei; Zhao, Lijuan; Chen, Guobing; Tu, Shumin; Fu, Long; Xia, Honghai; Yang, Dongliang; Wu, Bin; Ye, Baohua; Zhang, Guoxiu; Yang, Mei; Li, Qiang; Chen, Xiaomei; Pan, Xinting; Mao, Wenjian; Buxbaum, James; Jaber, Samir; Tong, Zhihui; Liu, Yuxiu; Windsor, John; Bellomo, Rinaldo; Li, Weiqin; hinese Acute Pancreatitis Clinical Trials Grp CAPCTG 分享 收藏
miR-429-3p mediates memory decline by targeting MKP-1 to reduce surface GluA1containing AMPA receptors in a mouse model of Alzheimer's disease 在阿尔茨海默氏病小鼠模型中，miR-429-3p通过靶向MKP-1减少表面含glua1的AMPA受体介导记忆力下降 Luo, Man; Pang, Yayan; Li, Junjie; Yi, Lilin; Wu, Bin; Tian, Qiuyun; He, Yan; Wang, Maoju; Xia, Lei; He, Guiqiong; Song, Weihong; Du, Yehong; Dong, Zhifang 分享 收藏
Toripalimab plus axitinib versus sunitinib as first-line treatment for advanced renal cell carcinoma: RENOTORCH, a randomized, open-label, phase III study Yan, X. Q.; Yey, M. J.; Zou, Q.; Chen, P.; He, Z. S.; Wu, B.; He, D. L.; He, C. H.; Xue, X. Y.; Ji, Z. G.; Chen, H.; Zhang, S.; Liu, Y. P.; Zhang, X. D.; Fu, C.; Xu, D. F.; Qiu, M. X.; Lv, J. J.; Huang, J.; Ren, X. B.; Cheng, Y.; Qin, W. J.; Zhang, X.; Zhou, F. J.; Ma, L. L.; Guo, J. M.; Ding, D. G.; Wei, S. Z.; He, Y.; Guo, H. Q.; Shi, B. K.; Liu, L.; Liu, F.; Hu, Z. Q.; Jin, X. M.; Yang, L.; Zhu, S. X.; Liu, J. H.; Huang, Y. H.; Xu, T.; Liu, B.; Sun, T.; Wang, Z. J.; Jiang, H. W.; Yu, D. X.; Zhou, A. P.; Jiang, J.; Luan, G. D.; Jin, C. L.; Xu, J.; Hu, J. X.; Huang, Y. R.; Guo, J.; Zhai, W.; Sheng, X. N. 分享 收藏
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice Zhu, Haixia; Cheng, Yin; Wang, Xianmei; Yang, Xing; Liu, Min; Liu, Jun; Liu, Shuqiao; Wang, Hongxiang; Zhang, Aizhen; Li, Runze; Ye, Chao; Zhang, Jian; Gao, Jiangang; Fu, Xiaolong; Wu, Bin 分享 收藏
Phase Ib/II trial of envafolimab, a novel subcutaneous singledomain anti-PD-L1 monoclonal antibody, plus lenvatinib in patients with selected advanced solid tumors Liu, T.; Feng, Y.; Xu, X.; Ren, X.; Jia, J.; Pan, H.; Wang, B.; Wu, B.; Cao, X.; Liu, J.; Yang, Y.; Xiao, S.; Qin, L.; Zhu, D.; Xu, S.; Huang, W. 分享 收藏
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Characterization of the semen, gut, and urine microbiota in patients with different semen abnormalities Cao, Tingshuai; Wang, Shangren; Pan, Yang; Guo, Feng; Wu, Bin; Zhang, Yingchun; Wang, Yujie; Tian, Jiaqing; Xing, Qingfei; Liu, Xiaoqiang 分享 收藏
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RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling Zhu, Haixia; Wen, Zongzhuang; Zhang, Aizhen; Liu, Dongyue; Wang, Hongxiang; Cheng, Yin; Yang, Xing; Xiao, Yu; Li, Jianyuan; Sun, Daqing; Wu, Bin; Gao, Jiangang 分享 收藏
Conditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice Hspa5的条件性缺失导致小鼠精子发生失败和雄性不育 Wen, Zongzhuang; Zhu, Haixia; Wang, Jing; Wu, Bin; Zhang, Aizhen; Zhao, Hui; Song, Chenyang; Liu, Shuangyuan; Cheng, Yin; Wang, Hongxiang; Li, Jianyuan; Sun, Daqing; Fu, Xiaolong; Gao, Jiangang; Liu, Min 分享 收藏
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