未登录 A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer 一种基于机器学习的多模态数据融合方法流程，用于贝伐珠单抗治疗转移性结直肠癌的预后风险分析 Thomas, Valentina; Nyamundanda, Gift; Larkeryd, Adrian; Hari, P. S.; Miller, Ian S.; Venken, Tom; Smeets, Dominiek; Boeckx, Bram; Betge, Johannes; Ebert, Matthias P. A.; Gaiser, Timo; Murphy, Verena; Kay, Elaine; Verheul, Henk M.; O'Farrell, Alice C.; Cremolini, Chiara; Marmorino, Federica; Gallagher, William M.; Barat, Ana; Klinger, Rut; Fender, Bozena; Ylstra, Bauke; van Grieken, Nicole; McNamara, Deborah A.; Hennessy, Bryan T.; Das, Sudipto; Moran, Bruce; O'Connor, Darran P.; Dienstmann, Rodrigo; Lambrechts, Diether; Prehn, Jochen H. M.; Sadanandam, Anguraj; Byrne, Annette T. 分享 收藏
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NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING NOTCH1通过重新激活STING逆转小细胞肺癌中的免疫抑制 Kim, Yoo Sun; Nabet, Barzin Y.; Cortez, Briana N.; Sun, Nai-Yun; Sebastian, Robin; Redon, Christophe E.; Ray, Anagh; Liu, Liang; Ishola, Afeez A.; Loew, Sarah; Dhall, Anjali; Sindiri, Sivasish; Gayevskiy, Velimir; Lee, Min-Jung; Rastogi, Shraddha; Sato, Nahoko; Kedei, Noemi; Andresson, Thorkell; Das, Sudipto; Kumar, Suresh; Bers, Alan E.; Zhang, Hongliang; Chiappori, Alberto; Gopal, Priyanka; Abazeed, Mohamed E.; Chen, Haobin; Aladjem, Mirit I.; Pommier, Yves; Velez, Moises J.; Shames, David S.; Roper, Nitin 分享 收藏
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Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33 KLHL17基因表达中的等位基因效应构成了 chr1p36.33 位点胰腺癌的全基因组关联信号。 Connelly, Katelyn E.; Hullin, Katherine; Abdolalizadeh, Ehssan; Zhong, Jun; Eiser, Daina; O'Brien, Aidan; Collins, Irene; Das, Sudipto; Duncan, Gerard; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Beane-Freeman, Laura; Berndt, Sonja I.; Buring, Julie E.; Campa, Daniele; Canzian, Federico; Chen, Yu; Chung, Charles C.; Eliassen, A. Heather; Gaziano, J. Michael; Giovannucci, Edward L.; Goodman, Phyllis J.; Haiman, Christopher A.; Hicks, Belynda; Hutchinson, Amy; Jones, Miranda R.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lee, I-Min; Lemarchand, Loic; Malats, Nuria; Manning, Michelle R.; Maennistoe, Satu; Milne, Roger; Moore, Steven C.; Mucci, Lorelei; Patel, Alpa V.; Peters, Ulrike; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Setiawan, Veronica W.; Shu, Xiao-Ou; Silverman, Debra; Stampfer, Meir J.; Southey, Melissa C.; Tobias, Geoffrey S.; Truong, Therese; Um, Caroline; Visvanathan, Kala; Wentzensen, Nicolas; White, Emily; Yuan, Chen; Zheng, Wei; Wactawski-Wende, Jean; Willett, Walter C.; Stoltzenberg-Solomon, Rachael Z.; Antwi, Samuel O.; Bracci, Paige M.; Gallinger, Steven; Goggins, Michael; Hassan, Manal; Holly, Elizabeth A.; Hung, Rayjean J.; Li, Donghui; Neale, Rachel E.; Rabe, Kari G.; Risch, Harvey A.; Yu, Herbert; Chanock, Stephen J.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Wolpin, Brian M.; Hoskins, Jason W.; Andresson, Thorkell; Smith, Jill P.; Amundadottir, Laufey T. 分享 收藏
Transfer RNA acetylation regulates in vivo mammalian stress signaling 转运RNA乙酰化调控活体内哺乳动物应激信号传导 Gamage, Supuni Thalalla; Khoogar, Roxane; Manage, Shereen Howpay; Daros, Judey T.; Crawford, McKenna C.; Georgeson, Joe; Polevoda, Bogdan V.; Sanders, Chelsea; Lee, Kendall A.; Nance, Kellie D.; Iyer, Vinithra; Kustanovich, Anatoly; Perez, Minervo; Thu, Chu T.; Nance, Sam R.; Amin, Ruhul; Miller, Christine N.; Holewinski, Ronald J.; Das, Sudipto; Meyer, Thomas J.; Koparde, Vishal; Yang, Acong; Jailwala, Parthav; Nguyen, Joe T.; Andresson, Thorkell; Gu, Shuo; Mock, Beverly A.; Edmondson, Elijah F.; Difilippantonio, Simone; Schwartz, Schraga; O'Connell, Mitchell R.; Meier, Jordan L. 分享 收藏
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Integrin beta-like 1 is regulated by DNA methylation and increased in heart failure patients Kerrigan, Lauren; Edgar, Kevin; Russell-Hallinan, Adam; Cappa, Oisin; Glezeva, Nadezhda; Galan-Arriola, Carlos; Oliver, Eduardo; Ibanez, Borja; Baugh, John; Collier, Patrick; Ledwidge, Mark; McDonald, Ken; Simpson, David; Das, Sudipto; Grieve, David J.; Watson, Chris J. 分享 收藏
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins Lu, Xiuxiu; Chandravanshi, Monika; Sabbasani, Venkata R.; Gaikwad, Snehal; Hughitt, V. Keith; Gyabaah-Kessie, Nana; Scroggins, Bradley T.; Das, Sudipto; Myint, Wazo; Clapp, Michelle E.; Schwieters, Charles D.; Dyba, Marzena A.; Bolhuis, Derek L.; Koscielniak, Janusz W.; Andresson, Thorkell; Emanuele, Michael J.; Brown, Nicholas G.; Matsuo, Hiroshi; Chari, Raj; Citrin, Deborah E.; Mock, Beverly A.; Swenson, Rolf E.; Walters, Kylie J. 分享 收藏
Deciphering epigenetic regulation of enhancers in high-risk prostate cancer Tuzova, A. V.; Moran, B.; Russell, N. M.; Das, S.; Delahaye, F.; Silva, R.; Barrett, C.; Watson, R. W. G.; O'Neill, A.; Gallagher, W. M.; Greally, J.; Perry, A. S. 分享 收藏
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-KB p50 Osei-Amponsa, Vasty; Chandravanshi, Monika; Lu, Xiuxiu; Magidson, Valentin; Das, Sudipto; Andresson, Thorkell; Dyba, Marzena; Sabbasani, Venkata R.; Swenson, Rolf E.; Fromont, Caroline; Shrestha, Biraj; Zhao, Yongmei; Clapp, Michelle E.; Chari, Raj; Walters, Kylie J. 分享 收藏
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum Yang, Mei; Mariano, Jennifer; Su, Rebecca; Smith, Christopher E.; Das, Sudipto; Gill, Catherine; Andresson, Thorkell; Loncarek, Jadranka; Tsai, Yien Che; Weissman, Allan M. 分享 收藏
Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer Finnegan, Ellen; Ding, Wei; Ude, Ziga; Terer, Sara; Mcgivern, Tadhg; Blumel, Anna M.; Kirwan, Grainne; Shao, Xinxin; Genua, Flavia; Yin, Xiaofei; Kel, Alexander; Fattah, Sarinj; Myer, Parvathi A.; Cryan, Sally-Ann; Prehn, Jochen H. M.; O'Connor, Darran P.; Brennan, Lorraine; Yochum, Gregory; Marmion, Celine J.; Das, Sudipto 分享 收藏
Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer Cosgrove, Nicola; Eustace, Alex J.; O'Donovan, Peter; Madden, Stephen F.; Moran, Bruce; Crown, John; Moulton, Brian; Morris, Patrick G.; Grogan, Liam; Breathnach, Oscar; Power, Colm; Allen, Michael; Walshe, Janice M.; Hill, Arnold D.; Blumel, Anna; O'Connor, Darren; Das, Sudipto; Milewska, Malgorzata; Fay, Joanna; Kay, Elaine; Toomey, Sinead; Hennessy, Bryan T.; Furney, Simon J. 分享 收藏
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck Nigam, Nupur; Bernard, Benjamin; Sevilla, Samantha; Kim, Sohyoung; Dar, Mohd Saleem; Tsai, Daniel; Robbins, Yvette; Burkitt, Kyunghee; Sievers, Cem; Allen, Clint T.; Bennett, Richard L.; Tettey, Theophilus T.; Carter, Benjamin; Rinaldi, Lorenzo; Lingen, Mark W.; Sater, Houssein; Edmondson, Elijah F.; Moshiri, Arfa; Saeed, Abbas; Cheng, Hui; Luo, Xiaolin; Brennan, Kevin; Koparde, Vishal; Chen, Chen; Das, Sudipto; Andresson, Thorkell; Abdelmaksoud, Abdalla; Murali, Madhavi; Sakata, Seiji; Takeuchi, Kengo; Chari, Raj; Nakamura, Yusuke; Uppaluri, Ravindra; Sunwoo, John B.; Van Waes, Carter; Licht, Jonathan D.; Hager, Gordon L.; Saloura, Vassiliki 分享 收藏
HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses Lin, Zhansong; Bashirova, Arman A.; Viard, Mathias; Garner, Lee; Quastel, Max; Beiersdorfer, Maya; Kasprzak, Wojciech K.; Akdag, Marjan; Yuki, Yuko; Ojeda, Pedro; Das, Sudipto; Andresson, Thorkell; Naranbhai, Vivek; Horowitz, Amir; McMichael, Andrew J.; Hoelzemer, Angelique; Gillespie, Geraldine M.; Garcia-Beltran, Wilfredo F.; Carrington, Mary 分享 收藏
An important role for hypomethylated integrin beta-like 1 in ischaemic cardiac fibroblasts Kerrigan, Lauren; Russell-Hallinan, Adam; Edgar, Kevin; Galan-Arriola, Carlos; Oliver, Eduardo; Ibanez, Borja; Collier, Pat; Moreavec, Christine; Ledwidge, Mark; McDonald, Ken; Das, Sudipto; Grieve, David; Watson, Chris 分享 收藏
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Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma Lu, Xiuxiu; Sabbasani, Venkata R.; Osei-Amponsa, Vasty; Evans, Christine N.; King, Julianna C.; Tarasov, Sergey G.; Dyba, Marzena; Das, Sudipto; Chan, King C.; Schwieters, Charles D.; Choudhari, Sulbha; Fromont, Caroline; Zhao, Yongmei; Tran, Bao; Chen, Xiang; Matsuo, Hiroshi; Andresson, Thorkell; Chari, Raj; Swenson, Rolf E.; Tarasova, Nadya I.; Walters, Kylie J. 分享 收藏
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