未登录 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019) 跨多个祖先的肺功能突出通路和慢性阻塞性肺疾病关联的新遗传信号 (第51卷，481页，2019) Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B.; Zhou, Jian; Hui, Jennie; Karrasch, Stefan; Imboden, Medea; Harris, Sarah E.; Marten, Jonathan; Enroth, Stefan; Kerr, Shona M.; Surakka, Ida; Vitart, Veronique; Lehtimaeki, Terho; Allen, Richard J.; Bakke, Per S.; Beaty, Terri H.; Bleecker, Eugene R.; Bosse, Yohan; Brandsma, Corry-Anke; Chen, Zhengming; Crapo, James D.; Danesh, John; DeMeo, Dawn L.; Dudbridge, Frank; Ewert, Ralf; Gieger, Christian; Gulsvik, Amund; Hansell, Anna L.; Hao, Ke; Hoffman, Joshua D.; Hokanson, John E.; Homuth, Georg; Joshi, Peter K.; Joubert, Philippe; Langenberg, Claudia; Li, Xuan; Li, Liming; Lin, Kuang; Lind, Lars; Locantore, Nicholas; Luan, Jian'an; Mahajan, Anubha; Maranville, Joseph C.; Murray, Alison; Nickle, David C.; Packer, Richard; Parker, Margaret M.; Paynton, Megan L.; Porteous, David J.; Prokopenko, Dmitry; Qiao, Dandi; Rawal, Rajesh; Runz, Heiko; Sayers, Ian; Sin, Don D.; Smith, Blair H.; Artigas, Maria Soler; Sparrow, David; Tal-Singer, Ruth; Timmers, Paul R. H. J.; Van den Berge, Maarten; Whittaker, John C.; Woodruff, Prescott G.; Yerges-Armstrong, Laura M.; Troyanskaya, Olga G.; Raitakari, Olli T.; Kaehoenen, Mika; Polasek, Ozren; Gyllensten, Ulf; Rudan, Igor; Deary, Ian J.; Probst-Hensch, Nicole M.; Schulz, Holger; James, Alan L.; Wilson, James F.; Stubbe, Beate; Zeggini, Eleftheria; Jarvelin, Marjo-Riitta; Wareham, Nick; Silverman, Edwin K.; Hayward, Caroline; Morris, Andrew P.; Butterworth, Adam S.; Scott, Robert A.; Walters, Robin G.; Meyers, Deborah A.; Cho, Michael H.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D.; Wain, Louise V. 分享 收藏
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The genetic determinants of recurrent somatic mutations in 43,693 blood genomes Weinstock, Joshua S.; Laurie, Cecelia A.; Broome, Jai G.; Taylor, Kent D.; Guo, Xiuqing; Shuldiner, Alan R.; O'Connell, Jeffrey R.; Lewis, Joshua P.; Boerwinkle, Eric; Barnes, Kathleen C.; Chami, Nathalie; Kenny, Eimear E.; Loos, Ruth J. F.; Fornage, Myriam; Redline, Susan; Cade, Brian E.; Gilliland, Frank D.; Chen, Zhanghua; Gauderman, W. James; Kumar, Rajesh; Grammer, Leslie; Schleimer, Robert P.; Psaty, Bruce M.; Bis, Joshua C.; Brody, Jennifer A.; Silverman, Edwin K.; Yun, Jeong H.; Qiao, Dandi; Weiss, Scott T.; Lasky-Su, Jessica; DeMeo, Dawn L.; Palmer, Nicholette D.; Freedman, Barry I.; Bowden, Donald W.; Cho, Michael H.; Vasan, Ramachandran S.; Johnson, Andrew D.; Yanek, Lisa R.; Becker, Lewis C.; Kardia, Sharon; He, Jiang; Kaplan, Robert; Heckbert, Susan R.; Smith, Nicholas L.; Wiggins, Kerri L.; Arnett, Donna K.; Irvin, Marguerite R.; Tiwari, Hemant; Correa, Adolfo; Raffield, Laura M.; Gao, Yan; de Andrade, Mariza; Rotter, Jerome I.; Rich, Stephen S.; Manichaikul, Ani W.; Konkle, Barbara A.; Johnsen, Jill M.; Wheeler, Marsha M.; Custer, Brian S.; Duggirala, Ravindranath; Curran, Joanne E.; Blangero, John; Gui, Hongsheng; Xiao, Shujie; Williams, L. Keoki; Meyers, Deborah A.; Li, Xingnan; Ortega, Victor; McGarvey, Stephen; Gu, C. Charles; Chen, Yii-Der Ida; Lee, Wen-Jane; Shoemaker, M. Benjamin; Darbar, Dawood; Roden, Dan; Albert, Christine; Kooperberg, Charles; Desai, Pinkal; Blackwell, Thomas W.; Abecasis, Goncalo R.; V. Smith, Albert; Kang, Hyun M.; Mathias, Rasika; Natarajan, Pradeep; Jaiswal, Siddhartha; Reiner, Alexander P.; Bick, Alexander G. 分享 收藏
A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables Hecker, Julian; Prokopenko, Dmitry; Moll, Matthew; Lee, Sanghun; Kim, Wonji; Qiao, Dandi; Voorhies, Kirsten; Kim, Woori; Vansteelandt, Stijn; Hobbs, Brian D.; Cho, Michael H.; Silverman, Edwin K.; Lutz, Sharon M.; DeMeo, Dawn L.; Weiss, Scott T.; Lange, Christoph 分享 收藏
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Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data 使用全基因组序列数据评估罕见遗传变异对慢性阻塞性肺疾病表型的贡献 Kim, Wonji; Hecker, Julian; Barr, R. Graham; Boerwinkle, Eric; Cade, Brian; Correa, Adolfo; Dupuis, Josee; Gharib, Sina A.; Lange, Leslie; London, Stephanie J.; Morrison, Alanna C.; O'Connor, George T.; Oelsner, Elizabeth; Psaty, Bruce M.; Vasan, Ramachandran S.; Redline, Susan; Rich, Stephen S.; Rotter, Jerome, I; Yu, Bing; Lange, Christoph; Manichaikul, Ani; Zhou, Jin J.; Sofer, Tamar; Silverman, Edwin K.; Qiao, Dandi; Cho, Michael H. 分享 收藏
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program Hu, Xiaowei; Qiao, Dandi; Kim, Wonji; Moll, Matthew; Balte, Pallavi P.; Lange, Leslie A.; Bartz, Traci M.; Kumar, Rajesh; Li, Xingnan; Yu, Bing; Cade, Brian E.; Laurie, Cecelia A.; Sofer, Tamar; Ruczinski, Ingo; Nickerson, Deborah A.; Muzny, Donna M.; Metcalf, Ginger A.; Doddapaneni, Harshavardhan; Gabriel, Stacy; Gupta, Namrata; Dugan-Perez, Shannon; Cupples, L. Adrienne; Loehr, Laura R.; Jain, Deepti; Rotter, Jerome, I; Wilson, James G.; Psaty, Bruce M.; Fornage, Myriam; Morrison, Alanna C.; Vasan, Ramachandran S.; Washko, George; Rich, Stephen S.; O'Connor, George T.; Bleecker, Eugene; Kaplan, Robert C.; Kalhan, Ravi; Redline, Susan; Gharib, Sina A.; Meyers, Deborah; Ortega, Victor; Dupuis, Josee; London, Stephanie J.; Lappalainen, Tuuli; Oelsner, Elizabeth C.; Silverman, Edwin K.; Barr, R. Graham; Thornton, Timothy A.; Wheeler, Heather E.; Cho, Michael H.; Im, Hae Kyung; Manichaikul, Ani 分享 收藏
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential 孟德尔随机化支持端粒长度与不确定电位的克隆造血之间的双向因果关系 Nakao, Tetsushi; Bick, Alexander G.; Taub, Margaret A.; Zekavat, Seyedeh M.; Uddin, Md M.; Niroula, Abhishek; Carty, Cara L.; Lane, John; Honigberg, Michael C.; Weinstock, Joshua S.; Pampana, Akhil; Gibson, Christopher J.; Griffin, Gabriel K.; Clarke, Shoa L.; Bhattacharya, Romit; Assimes, Themistocles L.; Emery, Leslie S.; Stilp, Adrienne M.; Wong, Quenna; Broome, Jai; Laurie, Cecelia A.; Khan, Alyna T.; Smith, Albert, V; Blackwell, Thomas W.; Codd, Veryan; Nelson, Christopher P.; Yoneda, Zachary T.; Peralta, Juan M.; Bowden, Donald W.; Irvin, Marguerite R.; Boorgula, Meher; Zhao, Wei; Yanek, Lisa R.; Wiggins, Kerri L.; Hixson, James E.; Gu, C. Charles; Peloso, Gina M.; Roden, Dan M.; Reupena, Muagututi'a S.; Hwu, Chii-Min; DeMeo, Dawn L.; North, Kari E.; Kelly, Shannon; Musani, Solomon K.; Bis, Joshua C.; Lloyd-Jones, Donald M.; Johnsen, Jill M.; Preuss, Michael; Tracy, Russell P.; Peyser, Patricia A.; Qiao, Dandi; Desai, Pinkal; Curran, Joanne E.; Freedman, Barry, I; Tiwari, Hemant K.; Chavan, Sameer; Smith, Jennifer A.; Smith, Nicholas L.; Kelly, Tanika N.; Hidalgo, Bertha; Cupples, L. Adrienne; Weeks, Daniel E.; Hawley, Nicola L.; Minster, Ryan L.; Deka, Ranjan; Naseri, Take T.; de Las Fuentes, Lisa; Raffield, Laura M.; Morrison, Alanna C.; Vries, Paul S.; Ballantyne, Christie M.; Kenny, Eimear E.; Rich, Stephen S.; Whitsel, Eric A.; Cho, Michael H.; Shoemaker, M. Benjamin; Pace, Betty S.; Blangero, John; Palmer, Nicholette D.; Mitchell, Braxton D.; Shuldiner, Alan R.; Barnes, Kathleen C.; Redline, Susan; Kardia, Sharon L. R.; Abecasis, Goncalo R.; Becker, Lewis C.; Heckbert, Susan R.; He, Jiang; Post, Wendy; Arnett, Donna K.; Vasan, Ramachandran S.; Darbar, Dawood; Weiss, Scott T.; McGarvey, Stephen T.; de Andrade, Mariza; Chen, Yii-Der Ida; Kaplan, Robert C.; Meyers, Deborah A.; Custer, Brian S.; Correa, Adolfo; Psaty, Bruce M.; Fornage, Myriam; Manson, JoAnn E.; Boerwinkle, Eric; Konkle, Barbara A.; Loos, Ruth J. F.; Rotter, Jerome, I; Silverman, Edwin K.; Kooperberg, Charles; Danesh, John; Samani, Nilesh J.; Jaiswal, Siddhartha; Libby, Peter; Ellinor, Patrick T.; Pankratz, Nathan; Ebert, Benjamin L.; Reiner, Alexander P.; Mathias, Rasika A.; Do, Ron; Natarajan, Pradeep 分享 收藏
A polygenic risk score and age of diagnosis of COPD Zhang, Jingzhou; Xu, Hanfei; Qiao, Dandi; DeMeo, Dawn L.; Silverman, Edwin K.; O'Connor, George T.; Hobbs, Brian D.; Dupuis, Josee; Cho, Michael H.; Moll, Matthew 分享 收藏
Interstitial lung abnormalities are associated with decreased mean telomere length Putman, Rachel K.; Axelsson, Gisli Thor; Ash, Samuel Y.; Sanders, Jason L.; Menon, Aravind A.; Araki, Tetsuro; Nishino, Mizuki; Yanagawa, Masahiro; Gudmundsson, Elias F.; Qiao, Dandi; Estepar, Raul San Jose; Dupuis, Josee; O'Connor, George T.; Rosas, Ivan O.; Washko, George R.; El-Chemaly, Souheil; Raby, Benjamin A.; Gudnason, Vilmundur; DeMeo, Dawn L.; Silverman, Edwin K.; Hatabu, Hiroto; DeVivo, Immaculata; Cho, Michael H.; Gudmundsson, Gunnar; Hunninghake, Gary M. 分享 收藏
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Multiethnic genome-wide and HLA association study of total serum IgE level 血清总IgE水平的多民族全基因组与HLA关联研究 Daya, Michelle; Cox, Corey; Acevedo, Nathalie; Boorgula, Meher P.; Campbell, Monica; Chavan, Sameer; Cho, Michael H.; David, Gloria L.; Kachroo, Priyadarshini; Lasky-Su, Jessica; Li, Xingnan; McHugh, Caitlin P.; Qiao, Dandi; Rafaels, Nicholas; Beck, Lisa A.; Bleecker, Eugene R.; Caraballo, Luis; Cupples, Adrienne L.; Figueiredo, Camila A.; Gallo, Richard L.; Hanifin, Jon; Hansel, Nadia N.; Hata, Tissa R.; Hersh, Craig P.; Knight-Madden, Jennifer; Leung, Donald Y. M.; Guttman-Yassky, Emma; Meyers, Deborah A.; O'Connor, George; Ober, Carole; Ong, Peck Y.; Ortega, Victor E.; Paller, Amy S.; Putcha, Nirupama; Reed, Robert M.; Schneider, Lynda C.; Silverman, Edwin K.; Slifka, Mark K.; Spergel, Jonathan M.; Vasan, Ramachandran S.; Viaud-Martinez, Karine A.; Watson, Harold; Weiss, Scott T.; Ruczinski, Ingo; Beaty, Terri H.; Mathias, Rasika A.; Barnes, Kathleen C. 分享 收藏
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Heterozygosity of the Alpha 1-Antitrypsin Pi*Z Allele and Risk of Liver Disease Hakim, Aaron; Moll, Matthew; Qiao, Dandi; Liu, Jiangyuan; Lasky-Su, Jessica A.; Silverman, Edwin K.; Vilarinho, Silvia; Jiang, Z. Gordon; Hobbs, Brian D.; Cho, Michael H. 分享 收藏
Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries Kwong, Alan M.; Blackwell, Thomas W.; LeFaive, Jonathon; de Andrade, Mariza; Barnard, John; Barnes, Kathleen C.; Blangero, John; Boerwinkle, Eric; Burchard, Esteban G.; Cade, Brian E.; Chasman, Daniel, I; Chen, Han; Conomos, Matthew P.; Cupples, L. Adrienne; Ellinor, Patrick T.; Eng, Celeste; Gao, Yan; Guo, Xiuqing; Irvin, Marguerite Ryan; Kelly, Tanika N.; Kim, Wonji; Kooperberg, Charles; Lubitz, Steven A.; Mak, Angel C. Y.; Manichaikul, Ani W.; Mathias, Rasika A.; Montasser, May E.; Montgomery, Courtney G.; Musani, Solomon; Palmer, Nicholette D.; Peloso, Gina M.; Qiao, Dandi; Reiner, Alexander P.; Roden, Dan M.; Shoemaker, M. Benjamin; Smith, Jennifer A.; Smith, Nicholas L.; Su, Jessica Lasky; Tiwari, Hemant K.; Weeks, Daniel E.; Weiss, Scott T.; Scott, Laura J.; Smith, Albert, V; Abecasis, Goncalo R.; Boehnke, Michael; Kang, Hyun Min 分享 收藏
A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19 (vol 61, 103026, 2020) McElvaney, Oliver J.; Hobbs, Brian D.; Qiao, Dandi; McElvaney, Oisin F.; Moll, Matthew; McEvoy, Natalie L.; Clarke, Jennifer; O'Connor, Eoin; Walsh, Sean; Cho, Michael H.; Curley, Gerard F.; McElvaney, Noel G. 分享 收藏
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