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Associations between immune checkpoint inhibitor response, immune-related adverse events, and steroid use in RADIOHEAD: a prospective pan-tumor cohort study 免疫检查点抑制剂反应、免疫相关不良事件和糖皮质激素使用之间的关系：RADIOHEAD一项前瞻性泛肿瘤队列研究 Quandt, Zoe; Lucas, Anastasia; Liang, Samantha, I; Yang, Enjun; Stone, Samantha; Fadlullah, Muhammad Zaki Hidayatullah; Bayless, Nicholas L.; Marr, Sara Siebel; Thompson, Marshall A.; Padron, Lacey J.; Bucktrout, Samantha; Butterfield, Lisa H.; Tan, Aik Choon; Herold, Kevan C.; Bluestone, Jeffrey A.; Anderson, Mark S.; Spencer, Christine N.; Young, Arabella; Connolly, John E. 分享 收藏
Molecular analysis of acute pyelonephritis-excessive innate and attenuated adaptive immunity Ambite, Ines; Chao, Sing Ming; Rosenblad, Therese; Hopkins, Richard; Storm, Petter; Ng, Yong Hong; Ganesan, Indra; Linden, Magnus; Haq, Farhan; Tran, Thi Hien; Ahmadi, Shahram; Lee, Bernett; Chen, Swaine L.; Godaly, Gabriela; Brandstroem, Per; Connolly, John E.; Svanborg, Catharina 分享 收藏
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL driven adaptive immunity- 功能性治愈的慢性乙型肝炎患者的单细胞景观揭示了先天和改变的CD4-CTL驱动的适应性免疫的激活- Narmada, Balakrishnan Chakrapani; Khakpoor, Atefeh; Shirgaonkar, Niranjan; Narayanan, Sriram; Aw, Pauline Poh Kim; Singh, Malay; Ong, Kok Haur; Owino, Collins Oduor; Ng, Jane Wei Ting; Yew, Hui Chuing; Nasir, Nu Soibah Binte Mohamed; Au, Veonice Bijin; Sng, Reina; Kaliaperumal, Nivashini; Khine, Htet Htet Toe Wai; di Tocco, Francesca Casuscelli; Masayuki, Otsuka; Naikar, Shamita; Ng, Hui Xin; Chia, Su Li; Seah, Cindy Xin Yi; Alnawaz, Myra H. J.; Wai, Chris Lee Yoon; Tay, Amy Yuh Ling; Mangat, Kamarjit Singh; Chew, Valerie; Yu, Weimiao; Connolly, John Edward; Periyasamy, Giridharan; Plissonnier, Marie-Laure; Levrero, Massimo; Lim, Seng Gee; DasGupta, Ramanuj 分享 收藏
Small Extracellular Vesicles from Therapy-induced Senescent TNBC Elicit Paracrine Anti-tumour Effects Robert, Matius; Jakhar, Rekha; Au, Bijin Veonice; Eng, Gracie Wee Ling; Gao, Alvin Kunyao; Chuah, You Heng; Sachaphibulkij, Karishma; Lim, Lina Hsiu Kim; Ong, Derrick Sek Tong; Lim, Elaine Hsuen; Itahana, Yoko; Itahana, Koji; Cheong, Jit Kong; Connolly, John Edward; Crasta, Karen Carmelina 分享 收藏
Adjunctive Pascolizumab in Rifampicin-Susceptible Pulmonary Tuberculosis: Proof-of-Concept, Partially-Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial Paton, Nicholas I.; Gurumurthy, Meera; Lu, Qingshu; Leek, Francesca; Kwan, Philip; Koh, Hiromi W. L.; Molton, James; Mortera, Lalaine; Naval, Sullian; Abu Bakar, Zamzurina; Pang, Yong-Kek; Lum, Lionel; Lim, Tow Keang; Cross, Gail B.; Lekurwale, Ganesh; Choi, Hyungwon; Au, Veonice; Connolly, John; Hibberd, Martin; Green, Justin A. 分享 收藏
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Unanswered questions following reports of secondary malignancies after CAR-T cell therapy Car-t细胞治疗后继发性恶性肿瘤报告后未解决的问题 Levine, Bruce L.; Pasquini, Marcelo C.; Connolly, John E.; Porter, David L.; Gustafson, Michael P.; Boelens, Jaap J.; Horwitz, Edwin M.; Grupp, Stephan A.; Maus, Marcela V.; Locke, Frederick L.; Ciceri, Fabio; Ruggeri, Annalisa; Snowden, John; Heslop, Helen E.; Mackall, Crystal L.; June, Carl H.; Sureda, Anna M.; Perales, Miguel-Angel 分享 收藏
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Themis controls T cell activation, effector functions, and metabolism of peripheral CD8+ T cells Gautam, Namrata; Wojciech, Lukasz; Yap, Jiawei; Chua, Yen Leong; Ding, Eyan M. W.; Sim, Don C. N.; Tan, Alrina S. M.; Ahl, Patricia J.; Prasad, Mukul; Tung, Desmond W. H.; Connolly, John E.; Adriani, Giulia; Brzostek, Joanna; Gascoigne, Nicholas R. J. 分享 收藏
A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma Tan, Tira J.; Ang, W. X. Gladys; Wang, Who-Whong; Chong, Hui-Shan; Tan, Sze Huey; Cheong, Rachael; Chia, John Whay-Kuang; Syn, Nicholas L.; Shuen, Wai Ho; Ba, Rebecca; Kaliaperumal, Nivashini; Au, Bijin; Hopkins, Richard; Li, Xinhua; Tan, Aaron C.; Seet, Amanda O. L.; Connolly, John E.; Arkachaisri, Thaschawee; Chew, Valerie; Lajam, Ahmad Bin Mohamed; Guo, Dianyan; Chew, Marvin Z. W.; Wasser, Martin; Kumar, Pavanish; Albani, Salvatore; Toh, Han Chong 分享 收藏
A phase I trial of durvalumab (Durv) in combination with olaparib (Ola) and capivasertib (Cap) in patients (pts) with advanced or metastatic cancers (Ca) (MEDIPAC) Lim, J. S.; Sundar, R.; Wong, A.; Yong, W-P.; Soo, R.; Chee, C. E.; Lee, S. C.; Goh, B. C.; Dent, R.; Jeraj, S. Nathan; Kwok, L.; Schiavon, G.; Kaliaperumal, N.; Foxley, A.; Connolly, J. E.; Tan, D. S. 分享 收藏
Systemic inflammation, innate immunity and pathogenesis after Zika virus infection in cynomolgus macaques are modulated by strain-specificity within the Asian lineage de Alwis, Ruklanthi; Zellweger, Raphael M.; Chua, Edmond; Wang, Lin-Fa; Chawla, Tanu; Sessions, October M.; Marlier, Damien; Connolly, John E.; von Messling, Veronika; Anderson, Danielle E. 分享 收藏
Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells Lee, Wen-Hsin Sandy; Ye, Zhiyong; Cheung, Alice M. S.; Goh, Y. P. Sharon; Oh, Hsueh Ling Janice; Rajarethinam, Ravisankar; Yeo, Siok Ping; Soh, Mun Kuen; Li Chan, Esther Hian; Tan, Lip Kun; Tan, Soo-Yong; Chuah, Charles; Chng, Wee Joo; Connolly, John E.; Wang, Cheng-, I 分享 收藏
Bayesian analysis of cytokines and chemokine identifies immune pathways of HBsAg loss during chronic hepatitis B treatment Narayanan, Sriram; Au, Veonice Bijin; Khakpoor, Atefeh; Yan, Cheng; Ahl, Patricia J.; Kaliaperumal, Nivashini; Lee, Bernett; Xiang, Wen Wei; Wang, Juling; Lee, Chris; Tay, Amy; Lim, Seng Gee; Connolly, John E. 分享 收藏
Monocytic Myeloid-Derived Suppressor Cells Underpin Resistance to Adoptive T Cell Therapy in Nasopharyngeal Carcinoma Hopkins, Richard; Xiang, Wenwei; Marlier, Damien; Au, Veonice Bijin; Ching, Qianting; Wu, Lynn Xue; Guan, Rujun; Lee, Bernett; Chia, Whay-Kuang; Wang, Who-Whong; Wee, Joseph; Ng, Joanna; Cheong, Rachael; Han, Shuting; Chu, Axel; Chee, Chit Lai; Shuen, Timothy; Podinger, Michael; Lezhava, Alexander; Toh, Han Chong; Connolly, John E. 分享 收藏
Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency Tan, Enrica E. K.; Hopkins, Richard A.; Lim, Chrissie K.; Jamuar, Saumya S.; Ong, Christina; Thoon, Koh C.; Koh, Mark J. A.; Shin, Eun Mong; Lian, Derrick W. Q.; Weerasooriya, Madhushanee; Lee, Christopher Z. W.; Soetedjo, Andreas Alvin Pumomo; Lim, Chang Siang; Au, Veonice B.; Chua, Edmond; Lee, Hui Yin; Jones, Leigh Ann; James, Sharmy S.; Kaliaperumal, Nivashini; Kwok, Jeffery; Tan, Ee Shien; Thomas, Biju; Wu, Lynn Xue; Ho, Lena; Fairhurst, Anna Marie; Ginhoux, Florent; Teo, Adrian K. K.; Zhang, Yong Liang; Ong, Kok Huar; Yu, Weimiao; Venkatesh, Byrappa; Tergaonkar, Vinay; Reversade, Bruno; Chin, Keh Chuang; Tan, Ah Moy; Liew, Woei Kang; Connolly, John E. 分享 收藏
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