未登录 CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 基于CRISPR的基因破坏和整合高亲和力的WT1-specific T细胞受体可改善抗肿瘤T细胞功能 Ruggiero, Eliana; Carnevale, Erica; Prodeus, Aaron; Magnani, Zulma Irene; Camisa, Barbara; Merelli, Ivan; Politano, Claudia; Stasi, Lorena; Potenza, Alessia; Cianciotti, Beatrice Claudia; Manfredi, Francesco; Di Bono, Mattia; Vago, Luca; Tassara, Michela; Mastaglio, Sara; Ponzoni, Maurilio; Sanvito, Francesca; Liu, Dai; Balwani, Ishina; Galli, Rossella; Genua, Marco; Ostuni, Renato; Doglio, Matteo; O'Connell, Daniel; Dutta, Ivy; Yazinski, Stephanie Ann; McKee, Mark; Arredouani, Mohamed Simo; Schultes, Birgit; Ciceri, Fabio; Bonini, Chiara 分享 收藏
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis 转甲状腺素蛋白淀粉样变性的体内基因编辑CRISPR-Cas9 Gillmore, Julian D.; Gane, Ed; Taubel, Jorg; Kao, Justin; Fontana, Marianna; Maitland, Michael L.; Seitzer, Jessica; O'Connell, Daniel; Walsh, Kathryn R.; Wood, Kristy; Phillips, Jonathan; Xu, Yuanxin; Amaral, Adam; Boyd, Adam P.; Cehelsky, Jeffrey E.; McKee, Mark D.; Schiermeier, Andrew; Harari, Olivier; Murphy, Andrew; Kyratsous, Christos A.; Zambrowicz, Brian; Soltys, Randy; Gutstein, David E.; Leonard, John; Sepp-Lorenzino, Laura; Lebwohl, David 分享 收藏
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption Tang, Cheng-Chia; Andrade, Christian D. Castro; O'Meara, Maureen J.; Yoon, Sung-Hee; Sato, Tadatoshi; Brooks, Daniel J.; Bouxsein, Mary L.; Martins, Janaina da Silva; Wang, Jinhua; Gray, Nathanael S.; Misof, Barbara; Roschger, Paul; Boulin, Stephane; Klaushofer, Klaus; Velduis-Vlug, Annegreet; Vegting, Yosta; Rosen, Clifford J.; O'Connell, Daniel; Sundberg, Thomas B.; Xavier, Ramnik J.; Ung, Peter; Schlessinger, Avner; Kronenberg, Henry M.; Berdeaux, Rebecca; Foretz, Marc; Wein, Marc N. 分享 收藏
AN IN VIVO CRISPR/CAS9 SCREENING PLATFORM TO IDENTIFY T CELL ENHANCING EDITS IN DISTINCT SOLID TUMOR MICROENVIRONMENTS Becker, Amy; Luster, Troy; Balwani, Ishina; Shevale, Nachiket; Sun, Jingwei; Del Aguila, Erica; Jones, Jeff; Sridhar, Srijani; Patel, Nishit; O'Connell, Daniel; Lescarbeau, Reynald; Schultes, Birgit 分享 收藏
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Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes Graham, Daniel B.; Luo, Chengwei; O'Connell, Daniel J.; Lefkovith, Ariel; Brown, Eric M.; Yassour, Moran; Varma, Mukund; Abelin, Jennifer G.; Conway, Kara L.; Jasso, Guadalupe J.; Matar, Caline G.; Carr, Steven A.; Xavier, Ramnik J. 分享 收藏
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Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 Early, James O.; Menon, Deepthi; Wyse, Cathy A.; Cervantes-Silva, Mariana P.; Zaslona, Zbigniew; Carroll, Richard G.; Palsson-McDermott, Eva M.; Angiari, Stefano; Ryan, Dylan G.; Corcoran, Sarah E.; Timmons, George; Geiger, Sarah S.; Fitzpatrick, Darren J.; O'Connell, Daniel; Xavier, Ramnik J.; Hokamp, Karsten; O'Neill, Luke A. J.; Curtis, Annie M. 分享 收藏
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells Johannessen, Liv; Sundberg, Thomas B.; O'Connell, Daniel J.; Kolde, Raivo; Berstler, James; Billings, Katelyn J.; Khor, Bernard; Seashore-Ludlow, Brinton; Fassl, Anne; Russell, Caitlin N.; Latorre, Isabel J.; Jiang, Baishan; Graham, Daniel B.; Perez, Jose R.; Sicinski, Piotr; Phillips, Andrew J.; Schreiber, Stuart L.; Gray, Nathanael S.; Shamji, Alykhan F.; Xavier, Ramnik J. 分享 收藏
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Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells Sundberg, Thomas B.; Choi, Hwan Geun; Song, Joo-Hye; Russell, Caitlin N.; Hussain, Mahmud M.; Graham, Daniel B.; Khor, Bernard; Gagnon, John; O'Connell, Daniel J.; Narayan, Kavitha; Dancik, Vlado; Perez, Jose R.; Reinecker, Hans-Christian; Gray, Nathanael S.; Schreiber, Stuart L.; Xavier, Ramnik J.; Shamji, Alykhan F. 分享 收藏
Quantifying cell-generated mechanical forces within living embryonic tissues (vol 11, pg 183, 2014) Campas, Otger; Mammoto, Tadanori; Hasso, Sean; Sperling, Ralph A.; O'Connell, Daniel; Bischof, Ashley G.; Maas, Richard; Weitz, David A.; Mahadevan, L.; Ingber, Donald E. 分享 收藏
Quantifying cell-generated mechanical forces within living embryonic tissues (vol 11, pg 183, 2014) Campas, Otger; Mammoto, Tadanori; Hasso, Sean; Sperling, Ralph A.; O'Connell, Daniel; Bischof, Ashley G.; Maas, Richard; Weitz, David A.; Mahadevan, L.; Ingber, Donald E. 分享 收藏
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Collaborative behavioral management among parolees: drug use, crime and re-arrest in the Step'n Out randomized trial Friedmann, Peter D.; Green, Traci C.; Taxman, Faye S.; Harrington, Magdalena; Rhodes, Anne G.; Katz, Elizabeth; O'Connell, Daniel; Martin, Steven S.; Frisman, Linda K.; Litt, Mark; Burdon, William; Clarke, Jennifer G.; Fletcher, Bennett W. 分享 收藏
A Wnt-Bmp Feedback Circuit Controls Intertissue Signaling Dynamics in Tooth Organogenesis O'Connell, Daniel J.; Ho, Joshua W. K.; Mammoto, Tadanori; Turbe-Doan, Annick; O'Connell, Joyce T.; Haseley, Psalm S.; Koo, Samuel; Kamiya, Nobuhiro; Ingber, Donald E.; Park, Peter J.; Maas, Richard L. 分享 收藏
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