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I

Isabel Fabregat

instituto de salud carlos iii

60H指数
249论文数
1.1W被引数
收录论文 121
发表时间
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Inhibition of the ZEB1–BCL2 axis in cancer-associated fibroblasts as a strategy to improve chemotherapy response in intrahepatic cholangiocarcinoma抑制癌相关成纤维细胞中ZEB1–BCL2轴以改善肝内胆管癌的化疗反应
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-07-06
err0
errOAAI
errEster Gonzalez-Sanchez; Marie Vallette; Lucia Garcia-Collado; Aashreya Ravichandra; Mirko Minini; Allan Pavy; Josep Amengual; Carlos Andres Roldán-Hernández; Ana Martin Ramirez; Corentin Louis; Juan Jose Lozano; Isabel Fabregat; Nathalie Guedj; Valérie Paradis; Cedric Coulouarn; Lynda Aoudjehane; Laura Fouassier; Javier Vaquero
err分享
err收藏
The endonuclease MCPIP1 protects against liver cancer development in a sex-dependent manner by modulating β-catenin and CREB1( vol 8 , 101755 , 2026)MCPIP1核酸内切酶通过调节β-连环蛋白和CREB1，以性别依赖方式保护肝脏癌变发展（卷8，101755，2026）
errJHEP Reports
IF7.5
err2026-07-01
err0
PREAI
errKwapisz, Oliwia; Marona, Paulina; Gorka, Judyta; Myrczek, Rafal; Gonzalez-Sanchez, Ester; Bertran, Esther; Kotlinowski, Jerzy; Gluc, Maciej; Alay, Ania; Pydyn, Natalia; Kujdowicz, Monika; Ramos, Emilio; Fabregat, Isabel; Kus, Katarzyna Mie
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Regulatory Mechanisms of SPARC Overexpression in Melanoma ProgressionSPARC高表达在黑色素瘤进展中的调控机制
errInternational Journal of Molecular Sciences
IF4.9
err2026-03-03
err0
errOAAI
errAntònia Vinyals; Josep R. Ferreres; Rafael Campos-Martín; Olga J. C. Torres; Jessica Mainez; Joan A. Puig-Butillé; Joaquim Marcoval; Susana Puig; Isabel Fabregat; Àngels Fabra
err分享
err收藏
The endonuclease MCPIP1 protects against liver cancer development in a sex-dependent manner by modulating β-catenin and CREB1
errJHEP Reports
IF7.5
err2026-01-29
err0
errOAAI
errOliwia Kwapisz; Paulina Marona; Judyta Gorka; Rafał Myrczek; Ester Gonzalez-Sanchez; Esther Bertran; Jerzy Kotlinowski; Maciej Głuc; Ania Alay; Natalia Pydyn; Monika Kujdowicz; Emilio Ramos; Isabel Fabregat; Katarzyna Miekus
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Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant responseMET在肝细胞中的适度增加通过促进有效的抗氧化反应来保护 Against胆汁淤积性肝损伤。
errFEBS JOURNAL
IF4.2
err2025-11-01
err0
PREAI
errGonzalez-Corralejo, Carlos; Garcia-Saez, Juan; Figueroa-Fuentes, Maria; Addante, Annalisa; Roncero, Cesareo; Lazcanoiturburu, Nerea; Pacheco, Beatriz; Sanz, Julian; Gato, Cristina; Fernandez-Calderon, Eva; Lopez, Maria de la O.; Gonzalez-Rodriguez, Agueda; Porras, Almudena; Maina, Flavio; Fabregat, Isabel; Herrera, Blanca; Sanchez, Aranzazu
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Decoding tumor–stroma interactions: from molecular crosstalk to therapeutic targets解析肿瘤-基质相互作用：从分子串扰到治疗靶点
errFEBS Open Bio
IF2.3
err2025-10-01
err0
errOAAI
errIsabel Fabregat
err分享
err收藏
New Experimental Mouse Models to Evaluate the Role of Transforming Growth Factor-Beta in Liver Tumorigenesis新型实验小鼠模型评估转化生长因子-β在肝脏肿瘤发生中的作用
errLiver International
IF5.2
err2025-09-10
err0
errOAAI
errAna Cantos-Cortes; Josep Amengual; Rut Espinosa-Sotelo; Esther Bertran; Javier Vaquero; Marina Ruiz de Galarreta; Pedro Molina-Sanchez; Teresa Serrano; Emilio Ramos; Mariona Calvo; Rosanna Scialpi; Francesco Dituri; Gianluigi Giannelli; Amaia Lujambio; Ester Gonzalez-Sanchez; Isabel Fabregat
err分享
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NADPH oxidase 1/4 dual inhibition impairs transforming growth factor-beta protumorigenic effects in cholangiocarcinoma cancer-associated fibroblastsNADPH氧化酶1/4双重抑制削弱胆管癌癌相关成纤维细胞中转化生长因子-β 的成瘤作用
errSignal Transduction and Targeted Therapy
IF52.7
err2025-08-18
err0
errOAAI
errJosep Amengual; Ester Gonzalez-Sanchez; Mariana Yáñez-Bartolome; Laura Sererols-Viñas; Aashreya Ravichandra; Celia Guiton; Noel P. Fuste; Ania Alay; Sara Hijazo-Pechero; Beatriz Martín-Mur; Marta Gut; Anna Esteve-Codina; Ana Cantos-Cortes; Rut Espinosa-Sotelo; Emilio Ramos; Teresa Serrano; Mariona Calvo; Berta Laquente; Joana Ferrer; Gabriel Pons; Andrés Mendez-Lucas; Steven Dooley; Sumera I. Ilyas; Marie Vallette; Lynda Aoudjehane; Marie Lequoy; Laura Fouassier; Cédric Coulouarn; Silvia Affò; Alexander Scheiter; Diego F. Calvisi; Tian V. Tian; Isabel Fabregat; Javier Vaquero
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Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers通过特异性和发育增强子，转录因子的顺序激活促进肝脏再生
errCell Genomics
IF9
err2025-05-22
err0
errOAAI
errPalmira Llorens-Giralt; Marina Ruiz-Romero; Ramil Nurtdinov; Macarena Herranz-Itúrbide; Guillermo P. Vicent; Florenci Serras; Isabel Fabregat; Montserrat Corominas
err分享
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New Hepatocellular Carcinoma (HCC) Primary Cell Cultures as Models for Exploring Personalized Anti-TGF-β Therapies Based on Tumor Characteristics新型肝细胞癌（HCC）原代细胞培养物作为探索基于肿瘤特征的个性化抗TGF-β疗法的模型
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-03-08
err0
errOAAI
errScialpi, Rosanna; Espinosa-Sotelo, Rut; Bertran, Esther; Dituri, Francesco; Giannelli, Gianluigi; Fabregat, Isabel
err分享
err收藏
Harnessing transcriptional regulation of alternative end-joining to predict cancer treatment
errNAR CANCER
IF3.2
err2025-03-07
err0
errOAAI
errEspin, Roderic; Medina-Jover, Ferran; Siguenza-Andrade, Javier; Farran-Matas, Sonia; Mateo, Francesca; Figueras, Agnes; Sanz, Rosario T.; Vicent, Guillermo Pablo; Shabbir, Arzoo; Ruiz-Auladell, Lara; Racionero-Andres, Emilio; Garcia, Irene; Baiges, Alexandra; Franco-Luzon, Lidia; Martinez-Tebar, Adrian; Pardo-Cea, Miguel Angel; Martinez-Iniesta, Maria; Wang, Xieng Chen; Cuyas, Elisabet; Menendez, Javier A.; Lopez-Cerda, Marta; Munoz, Purificacion; Richaud, Ivonne; Raya, Angel; Fabregat, Isabel; Villanueva, Alberto; Serrat, Xenia; Ceron, Julian; Alemany, Montserrat; Guix, Ines; Herencia-Ropero, Andrea; Serra, Violeta; Krishnan, Rehna; Mekhail, Karim; Hakem, Razqallah; Bruna, Jordi; Barcellos-Hoff, Mary Helen; Vinals, Francesc; Aytes, Alvaro; Pujana, Miquel Angel
err分享
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Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression
errCELL DEATH & DISEASE
IF9.6
err2024-09-17
err1
errOAAI
errAmengual, Josep; Alay, Ania; Vaquero, Javier; Gonzalez-Sanchez, Ester; Bertran, Esther; Sanchez, Aranzazu; Herrera, Blanca; Meyer, Kathleen; Maus, Mate; Serrano, Manuel; Martinez-Chantar, Maria Luz; Fabregat, Isabel
err分享
err收藏
PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients
errMOLECULAR ONCOLOGY
IF4.5
err2024-07-08
err1
errOAAI
errFerreres, Josep R.; Vinyals, Antonia; Campos-Martin, Rafael; Espin, Roderic; Podlipnik, Sebastian; Ramos, Raquel; Bertran, Esther; Carrera, Cristina; Marcoval, Joaquim; Malvehy, Josep; Fabregat, Isabel; Puig, Susana; Fabra, Angels
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err收藏
The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche
errJOURNAL OF PATHOLOGY
IF5.2
err2024-06-14
err3
errOAAI
errGonzalez-Sanchez, Ester; Vaquero, Javier; Caballero-Diaz, Daniel; Grzelak, Jan; Fuste, Noel P.; Bertran, Esther; Amengual, Josep; Garcia-Saez, Juan; Martin-Mur, Beatriz; Gut, Marta; Esteve-Codina, Anna; Alay, Ania; Coulouarn, Cedric; Calero-Perez, Silvia; Valdecantos, Pilar; Valverde, Angela M.; Sanchez, Aranzazu; Herrera, Blanca; Fabregat, Isabel
err分享
err收藏
ROLE OF THE NADPH OXIDASE NOX4 IN THE REGULATION OF ENDOPLASMIC RETICULUM (ER) STRESS IN LIVER TUMOR CELLS
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2024-06-01
err0
PREAI
errGonfaus-Ortiz, Gemma; Penuelas-Haro, Irene; Sanchez-Vera, Ismael; Gil, Joan; Bertran, Esther; Fabregat, Isabel
err分享
err收藏
ROLE OF THE NADPH OXIDASE NOX4 IN THE LIVER TUMOUR MICROENVIRONMENT
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2024-06-01
err0
PREAI
errEspinosa-Sotelo, Rut; Penuelas-Haro, Irene; Herranz-Iturbide, Macarena; Caballero-Diaz, Daniel; Crosas-Molist, Eva; Bertran, Esther; Fabregat, Isabel
err分享
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DUAL NOX4/NOX1 INHIBITION BY SETANAXIB HALTS CHOLANGIOCARCINOMA PROGRESSION BY IMPAIRING CANCER ASSOCIATED FIBROBLAST ACTIVATION
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2024-06-01
err0
PREAI
errAmengual, Josep; Gonzalez-Sanchez, Ester; Fuste, Noel P.; Pons, Gabriel; Sererols-Vinas, Laura; Alay, Ania; Hijazo-Pechero, Sara; Martin-Mur, Beatriz; Esteve-Codina, Anna; Ferrer, Joana; Gores, Gregory J.; Ilyas, Sumera I.; Calvisi, Diego; Aoudjehane, Lynda; Fouassier, Laura; Coulouarn, Cedric; Affo, Silvia; Fabregat, Isabel; Vaquero, Javier
err分享
err收藏
Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma
errREDOX BIOLOGY
IF11.9
err2023-09-01
err5
errOAAI
errEspinosa-Sotelo, Rut; Fuste, Noel P.; Penuelas-Haro, Irene; Alay, Ania; Pons, Gabriel; Almodovar, Xenia; Albaladejo, Julia; Sanchez-Vera, Ismael; Bonilla-Amadeo, Ricard; Dituri, Francesco; Serino, Grazia; Ramos, Emilio; Serrano, Teresa; Calvo, Mariona; Martinez-Chantar, Maria Luz; Giannelli, Gianluigi; Bertran, Esther; Fabregat, Isabel
err分享
err收藏
Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models (vol 42, 197, 2023)
errJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
err2023-08-18
err2
errOAAI
errCentonze, Matteo; Di Conza, Giusy; Lahn, Michael; Fabregat, Isabel; Dituri, Francesco; Gigante, Isabella; Serino, Grazia; Scialpi, Rosanna; Carrieri, Livianna; Negro, Roberto; Pizzuto, Elena; Giannelli, Gianluigi
err分享
err收藏
Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical modelsAutotaxin抑制剂IOA-289在临床前模型中减少胃肠道癌症进展
errJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
err2023-08-08
err14
errOAAI
errCentonze, Matteo; Di Conza, Giusy; Lahn, Michael; Fabregat, Isabel; Dituri, Francesco; Gigante, Isabella; Serino, Grazia; Scialpi, Rosanna; Carrieri, Livianna; Negro, Roberto; Pizzuto, Elena; Giannelli, Gianluigi
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Douglas R. Green
H 指数: 199 · 论文数: 966
G
Gregory J. Gores
H 指数: 164 · 论文数: 1.0K
P
Pier Paolo Pandolfi
H 指数: 160 · 论文数: 818
P
Peter ten Dijke
H 指数: 147 · 论文数: 795
C
Carl‐Henrik Heldin
H 指数: 144 · 论文数: 652
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