Herbert Y. Gaisano - Publications, H-index & Citations

Herbert Y. Gaisano

university of toronto

64H指数

268论文数

1.1W被引数

收录论文 165

发表时间

No Blood? No Problem: Blood-Free Perfusion of Human and Porcine Pancreases - A Feasibility Study 无血液？没问题：人及猪胰腺的无血灌注——一项可行性研究

American Journal of Transplantation

IF8.2

2025-08-02

PREAI

C. Parmentier; J. Manuel; H. Gu; H. Gaisano; F. Kang; H. Jeon; K. Wang; F. Calderon Novoa; K. Nakamura; S. Ganesh; C. Hobeika; S. Kalimuthu; S. Ray; J. Coleman; Q. Qu; E. Mizdrak; M. Selzner; T. Reichman

Bacterial ADP-heptose triggers stem cell regeneration in the intestinal epithelium following injury 细菌ADP-庚糖在损伤后触发肠道上皮的干细胞再生

Cell Stem Cell

IF20.4

2025-07-11

PREAI

Shawn Goyal; Cynthia X. Guo; Ojas Singh; Adrienne Ranger; Caitlin F. Harrigan; Justin Meade; Alexander Luchak; Derek K. Tsang; Herbert Y. Gaisano; Nan Gao; Scott A. Yuzwa; Jeffrey L. Wrana; Dana J. Philpott; Scott D. Gray-Owen; Stephen E. Girardin

Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium Gasdermin-D孔道诱导一种失活的caspase-4切割，该切割限制了肠上皮中IL-18的产生。

COMMUNICATIONS BIOLOGY

IF5.1

2025-05-13

OAAI

Bruce, J. K.; Li, L. Y.; Tang, Y.; Forster, E. G.; Winsor, N. J.; Bi, P. Y.; Krustev, C.; Keely, S.; Lee, J. E.; Rohde, J. R.; Gaisano, H. Y.; Philpott, D. J.; Girardin, S. E.

Septin5 deletion enhances β-cell exocytosis by releasing microtubule-tethered insulin granules onto plasma membrane Septin5基因敲除通过释放微管锚定的胰岛素颗粒至质膜来增强β细胞胞吐作用。

NATURE COMMUNICATIONS

IF15.7

2025-03-19

OAAI

Xie, Li; Kang, Fei; Qin, Tairan; Kang, Youhou; Liang, Tao; Xie, Huanli; Froese, Carol D.; Xie, Hong; Au, Aaron; Yip, Christopher M.; Trimble, William S.; Gaisano, Herbert Y.

KATP Channels as Target for Remodeling Connectivity in Type 2 Diabetes ATP敏感性钾通道作为2型糖尿病中重塑连接的靶点

FUNCTION

IF3.8

2025-03-17

OAAI

Kang, Fei; Gaisano, Herbert Y.

Beta cell specific ZnT8 gene deficiency and resulting loss in zinc content significantly improve insulin secretion Β 细胞特异性ZnT8基因缺陷和由此导致的锌含量损失显著改善胰岛素分泌

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2024-12-01

OAAI

Piro, Anthony; Luo, Yihan; Zhang, Ziyi; Ye, Wenyue; Kang, Fei; Xie, Li; Wang, Yufeng; Dai, Feihan F.; Gaisano, Herbert Y.; Rocheleau, Jonathan, V; Prentice, Kacey J.; Wheeler, Michael B.

Total bilirubin modified the association between diabetes and stroke: a cross-sectional study from NHANES 2011-2016 总胆红素改变糖尿病和卒中之间的关联: 来自NHANES 2011-2016的横断面研究

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IF7.5

2024-09-04

PREAI

Xia, Zhang; Xu, Guozheng; Zhao, Mingyang; Li, Yuhao; Ye, Peiyu; Liu, Yijian; Gaisano, Herbert Y.; He, Yan

Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell 人类1型糖尿病的胰岛自身免疫: 从 β 细胞的角度出发和发展

DIABETOLOGIA

IF10.2

2023-07-25

OAAI

Thompson, Peter J.; Pipella, Jasmine; Rutter, Guy A.; Gaisano, Herbert Y.; Santamaria, Pere

Factors associated with nocturnal and diurnal glycemic variability in patients with type 2 diabetes: a cross-sectional study

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

IF3.5

2023-06-24

PREAI

Jiang, J.; Xia, Z.; Zheng, D.; Li, Y.; Li, F.; Wang, W.; Ding, S.; Zhang, J.; Su, X.; Zhai, Q.; Zuo, Y.; Zhang, Y.; Gaisano, H. Y.; He, Y.; Sun, J.

Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure

CELL REPORTS MEDICINE

IF10.6

2023-05-01

OAAI

Yadav, Jitender; Liang, Tao; Qin, Taira; Nathan, Nayanan; Schwenger, Katherine J. P.; Pickel, Lauren; Xie, Li; Lei, Helena; Winer, Daniel A.; Maughan, Heather; Robertson, Susan J.; Woo, Minna; Lou, Wendy; Banks, Kate; Jackson, Timothy; Okrainec, Allan; Hota, Susy S.; Poutanen, Susan M.; Sung, Hoon-Ki; Allard, Johane P.; Philpott, Dana J.; Gaisano, Herbert Y.

Caspase-3-dependent β-cell apoptosis in the initiation of autoimmune diabetes mellitus

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

152

OAAI

Liadis, N; Murakami, K; Eweida, M; Elford, AR; Sheu, L; Gaisano, HY; Hakem, R; Ohashi, PS; Woo, M

Association between residual islet beta-cell function and achieving the target of time in range in inpatients with type 2 diabetes undergoing antidiabetic treatment: An observation study

DIABETES OBESITY & METABOLISM

IF5.7

2023-03-07

PREAI

Xia, Zhang; You, Wenjun; Li, Yuhao; Li, Feng; Hao, Shuai; Sun, Yihan; Li, Na; Lin, Lu; Dou, Jingtao; Su, Xin; Zhai, Qi; Zuo, Yingting; Zhang, Yibo; Gaisano, Herbert Y.; Zheng, Deqiang; He, Yan; Jiang, Jiajia

Higher systolic blood pressure is specifically associated with better islet beta-cell function in T2DM patients with high glycemic level

CARDIOVASCULAR DIABETOLOGY

IF10.6

2022-12-19

OAAI

Xia, Zhang; Song, Lijuan; Fang, Dongdong; You, Wenjun; Li, Feng; Zheng, Deqiang; Li, Yuhao; Lin, Lu; Dou, Jingtao; Su, Xin; Zhai, Qi; Zuo, Yingting; Zhang, Yibo; Gaisano, Herbert Y. Y.; Jiang, Jiajia; He, Yan

Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis

NATURE COMMUNICATIONS

IF15.7

2022-10-31

OAAI

Kang, Fei; Xie, Li; Qin, Tairan; Miao, Yifan; Kang, Youhou; Takahashi, Toshimasa; Liang, Tao; Xie, Huanli; Gaisano, Herbert Y.

Effect of faecal microbial transplant via colonoscopy in patients with severe obesity and insulin resistance: A randomized double-blind, placebo-controlled Phase 2 trial

DIABETES OBESITY & METABOLISM

IF5.7

2022-10-28

PREAI

Ghorbani, Yasaman; Schwenger, Katherine J. P.; Sharma, Divya; Jung, Hyejung; Yadav, Jitender; Xu, Wei; Lou, Wendy; Poutanen, Susan; Hota, Susy S.; Comelli, Elena M.; Philpott, Dana; Jackson, Timothy D.; Okrainec, Allan; Gaisano, Herbert Y.; Allard, Johane P.

Design of a versatile microfluidic device for imaging precision-cut-tissue slices

BIOFABRICATION

IF8

2022-07-19

OAAI

Rafiei, Nafiseh; Moghadam, Mohammadamir G.; Au, Aaron; Regeenes, Romario; Chidambaram, Subbulakshmi; Liang, Tao; Wang, Yufeng; Yip, Christopher M.; Gaisano, Herbert; Rocheleau, Jonathan, V

Association between changes in lipid indexes and early progression of kidney dysfunction in participants with normal estimated glomerular filtration rate: a prospective cohort study

ENDOCRINE

IF2.9

2022-03-03

PREAI

Zhai, Qi; Dou, Jingtao; Wen, Jing; Wang, Meiping; Zuo, Yingting; Su, Xin; Zhang, Yibo; Gaisano, Herbert; Mu, Yiming; He, Yan

Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2022-01-01

OAAI

Mareninova, Olga A.; Dillon, Dustin L.; Wightman, Carli J. M.; Yakubov, Iskandar; Takahashi, Toshimasa; Gaisano, Herbert Y.; Munson, Keith; Ohmuraya, Masaki; Dawson, David; Gukovsky, Ilya; Gukovskaya, Anna S.

Glomerular Hyperfiltration Interacts With Abnormal Metabolism to Enhance Arterial Stiffness in Middle-Aged and Elderly People

FRONTIERS IN MEDICINE

IF3

2021-10-21

OAAI

Zhai, Qi; Wen, Jing; Wang, Meiping; Zuo, Yingting; Su, Xin; Zhang, Yibo; Gaisano, Herbert; He, Yan

Dysregulation of mannose-6-phosphate-dependent cholesterol homeostasis in acinar cells mediates pancreatitis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-08-02

OAAI

Mareninova, Olga A.; Vegh, Eszter T.; Shalbueva, Natalia; Wightman, Carli J. M.; Dillon, Dustin L.; Malla, Sudarshan; Xie, Yan; Takahashi, Toshimasa; Rakonczay, Zoltan, Jr.; French, Samuel W.; Gaisano, Herbert Y.; Gorelick, Fred S.; Pandol, Stephen J.; Bensinger, Steven J.; Davidson, Nicholas O.; Dawson, David W.; Gukovsky, Ilya; Gukovskaya, Anna S.

研究方向