Alan A. DiSpirito - Publications, H-index & Citations

Alan A. DiSpirito

Iowa State University

51H指数

150论文数

7.7K被引数

收录论文 53

发表时间

Cuproptosis in iron overload hepatocytes 铜死亡在铁过载肝细胞中

Cell Death & Disease

IF9.6

2026-09-19

OAAI

Judith Sailer; Jonas Gottal; Leon Kaub; Adrian T. Jauch; Jonas Engler; Carola Eberhagen; Christine von Toerne; Lea Hansen-Palmus; Valerie Wachinger; Banu Akdogan; Stefan Engelhardt; Percy Knolle; Alan A. DiSpirito; Ulrike Protzer; Maja Vujić Spasić; Hans Zischka

Rapid transcellular hepatic copper depletion by ARBM-101 rescues severe liver damage in Wilson disease rodents ARBM-101通过快速跨细胞方式耗竭肝铜，可挽救Wilson病模型鼠的严重肝脏损伤

Biomedicine & Pharmacotherapy

IF7.5

2025-12-04

OAAI

Jonas Engler; Eun-Jung Kim; Dasol Kim; Noreene M. Shibata; Emilie Munk Lynderup; Mikkel H. Vendelbo; Banu Akdogan; Judith Sailer; Adriana Fontes; Carola Eberhagen; Tamara Rieder; Quirin Reinold; Hongjae Lee; Dongsik Park; Chunwon Jung; Weonbin Im; Susanne I. Wudy; Karin Kleigrewe; Stefan Engelhardt; Alan A. DiSpirito

Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI 甲烷杆菌素能快速促进威尔逊病大鼠模型中的胆汁铜排泄，并通过64Cu PET/MRI进行可视化。

British Journal of Pharmacology

IF7.7

2025-09-01

OAAI

Emilie Munk Lynderup; Mikkel Holm Vendelbo; Frederik Teicher Kirk; Karina Højrup Vase; Aage Kristian Olsen Alstrup; Tamara Rieder; Alan A. DiSpirito; Jeremy D. Semrau; Tea Lund Laursen; Peter Ott; Hans Zischka; Thomas Damgaard Sandahl

Copper impairs the intestinal barrier integrity in Wilson disease

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2024-09-01

OAAI

Fontes, Adriana; Pierson, Hannah; Bierla, Joanna B.; Eberhagen, Carola; Kinschel, Jennifer; Akdogan, Banu; Rieder, Tamara; Sailer, Judith; Reinold, Quirin; Cielecka-Kuszyk, Joanna; Szymanska, Sylwia; Neff, Frauke; Steiger, Katja; Seelbach, Olga; Zibert, Andree; Schmidt, Hartmut H.; Hauck, Stefanie M.; von Toerne, Christine; Michalke, Bernhard; Semrau, Jeremy D.; DiSpirito, Ana M.; Ramalho-Santo, Joao; Kroemer, Guido; Polishchuk, Roman; Azul, Anabela Marisa; Dispirito, Alan; Socha, Piotr; Lutsenko, Svetlana; Zischka, Hans

Heterologous Biosynthesis of Methanobactin from Methylocystis sp. Strain SB2 in Methylosinus trichosporium OB3b

ACS SYNTHETIC BIOLOGY

IF3.9

2024-08-07

PREAI

Peng, Peng; Dispirito, Alan A.; Lewis, Braden J.; Nott, Joel D.; Semrau, Jeremy D.

MmoD regulates soluble methane monooxygenase and methanobactin production in Methylosinus trichosporium OB3b

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2023-12-21

OAAI

Peng, Peng; Yang, Junwon; Dispirito, Alan A.; Semrau, Jeremy D.

ARBM101 (Methanobactin SB2) Drains Excess Liver Copper via Biliary Excretion in Wilson's Disease Rats ARBM101 (甲烷菌素SB2) 通过威尔逊氏病大鼠的胆汁排泄排泄过量的肝铜

GASTROENTEROLOGY

IF25.1

2023-07-01

OAAI

Einer, Claudia; Munk, Ditte Emilie; Park, Eok; Akdogan, Banu; Nagel, Judith; Lichtmannegger, Josef; Eberhagen, Carola; Rieder, Tamara; Vendelbo, Mikkel H.; Michalke, Bernhard; Wimmer, Ralf; Blutke, Andreas; Feuchtinger, Annette; Dershwitz, Philip; DiSpirito, Ana M.; Islam, Tawhidul; Castro, Rui E.; Min, Byong-Keol; Kim, TaeWon; Choi, Seoyoun; Kim, Dasol; Jung, Chunwon; Lee, Hongjae; Park, Dongsik; Im, Weonbin; Eun, So-Young; Cho, You-Hee; Semrau, Jeremy D.; Rodrigues, Cecilia M. P.; Hohenester, Simon; Sandahl, Thomas Damgaard; DiSpirito, Alan A.; Zischka, Hans

Multiple Mechanisms for Copper Uptake by Methylosinus trichosporium OB3b in the Presence of Heterologous Methanobactin

MBIO

IF4.7

2022-10-26

OAAI

Peng, Peng; Gu, Wenyu; DiSpirito, Alan A.; Semrau, Jeremy D.

Diffusion of H2S from anaerobic thiolated ligand biodegradation rapidly generates bioavailable mercury

ENVIRONMENTAL MICROBIOLOGY

IF4

2022-06-12

OAAI

Stenzler, Benjamin R.; Zhang, Rui; Semrau, Jeremy D.; DiSpirito, Alan A.; Poulain, Alexandre J.

Variable Inhibition of Nitrous Oxide Reduction in Denitrifying Bacteria by Different Forms of Methanobactin

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2022-04-12

OAAI

Chang, Jin; Peng, Peng; DiSpirito, Alan A.; Semrau, Jeremy D.

MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b 不需要MbnC来形成甲基单孢菌OB3b甲烷菌素中的N端恶唑酮

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2022-01-25

OAAI

Dershwitz, Philip; Gu, Wenyu; Roche, Julien; Kang-Yun, Christina S.; Semrau, Jeremy D.; Bobik, Thomas A.; Fulton, Bruce; Zischka, Hans; DiSpirito, Alan A.

Two TonB-Dependent Transporters in Methylosinus trichosporium OB3b Are Responsible for Uptake of Different Forms of Methanobactin and Are Involved in the Canonical Copper Switch

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2022-01-11

OAAI

Peng, Peng; Kang-Yun, Christina S.; Chang, Jin; Gu, Wenyu; DiSpirito, Alan A.; Semrau, Jeremy D.

Spectroscopic and computational investigations of organometallic complexation of group 12 transition metals by methanobactins from Methylocystis sp. SB2

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2021-10-01

OAAI

Eckert, Peter; Johs, Alexander; Semrau, Jeremy D.; DiSpirito, Alan A.; Richardson, Jocelyn; Sarangi, Ritimukta; Herndon, Elizabeth; Gu, Baohua; Pierce, Eric M.

Evidence for methanobactin Theft and novel chalkophore production in methanotrophs: impact on methanotrophic-mediated methylmercury degradation 甲烷营养菌中甲烷菌素盗窃和新型chalkophore产生的证据: 对甲烷营养菌介导的甲基汞降解的影响

ISME JOURNAL

IF10

2021-07-21

OAAI

Kang-Yun, Christina S.; Liang, Xujun; Dershwitz, Philip; Gu, Wenyu; Schepers, Aloys; Flatley, Andrew; Lichtmannegger, Josef; Zischka, Hans; Zhang, Lijie; Lu, Xia; Gu, Baohua; Ledesma, Joshua C.; Pelger, Daly J.; DiSpirito, Alan A.; Semrau, Jeremy D.

Oxygen Generation via Water Splitting by a Novel Biogenic Metal Ion-Binding Compound 新型生物金属离子结合化合物通过水分解产生氧气

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2021-06-25

OAAI

Dershwitz, Philip; Bandow, Nathan L.; Yang, Junwon; Semrau, Jeremy D.; McEllistrem, Marcus T.; Heinze, Rafael A.; Fonseca, Matheus; Ledesma, Joshua C.; Jennett, Jacob R.; DiSpirito, Ana M.; Athwal, Navjot S.; Hargrove, Mark S.; Bobik, Thomas A.; Zischka, Hans; DiSpirito, Alan A.

Synergistic Effects of a Chalkophore, Methanobactin, on Microbial Methylation of Mercury

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2020-05-19

OAAI

Yin, Xixiang; Wang, Lihong; Zhang, Lijie; Chen, Hongmei; Liang, Xujun; Lu, Xia; DiSpirito, Alan A.; Semrau, Jeremy D.; Gu, Baohua

A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2019-01-01

OAAI

Einer, Claudia; Leitzinger, Christin; Lichtmannegger, Josef; Eberhagen, Carola; Rieder, Tamara; Borchard, Sabine; Wimmer, Ralf; Denk, Gerald; Popper, Bastian; Neff, Frauke; Polishchuk, Elena, V; Polishchuk, Roman S.; Hauck, Stefanie M.; von Toerne, Christine; Mueller, Jennifer-Christin; Karst, Uwe; Baral, Bipin S.; DiSpirito, Alan A.; Kremer, Andreas E.; Semrau, Jeremy; Weiss, Karl Heinz; Hohenester, Simon; Zischka, Hans

Metals and Methanotrophy

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2018-03-15

122

OAAI

Semrau, Jeremy D.; DiSpirito, Alan A.; Gu, Wenyu; Yoon, Sukhwan

Methanobactin from Methylosinus trichosporium OB3b inhibits N2O reduction in denitrifiers

ISME JOURNAL

IF10

2018-01-12

OAAI