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M

Marianne R. Spalinger

university of zurich
H指数:33
被引数:3,591

个人简介

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工作经历

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荣誉奖项

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Indirect inhibition of the NLRP3-interleukin-1β axis contributes to the efficacy of JAK1 inhibitors in experimental colitis and human ulcerative colitis

间接抑制NLRP3-白细胞介素-1β轴有助于JAK1抑制剂在实验性结肠炎和人类溃疡性结肠炎中的疗效

Nature Communications
IF15.7
2026-04-180
OAAI
Beibei Liu; Marianne R. Spalinger; Annalisa Invernizzi; Eike Gerdes; Babett Steglich; Marlene Schwarzfischer; Andres Machicote; Penelope Pelczar; Doris Pöhlmann; Mikolaj Nawrocki; Marius Böttcher; Ayob Aleko; Lis Noelia Velasquez; Sandra Wende; Franziska Stallbaum; Justus Neuendorff; Saskia Grosshauser; Franziska Muscate; Gemma Douilhet; Laura Garcia Perez; Morsal Sabihi; Katharina Möller; Florian Viehweger; Jan P. Sutter; Christoph Kilian; Yogesh Kumar; Thorben Fründt; Guido Sauter; Thomas Rösch; Nicola Gagliani; Amedeo Caflisch; Michael Scharl; Samuel Huber
Endometriosis-associated infertility alters the microRNA signatures of cumulus cells with a particularly pronounced effect in oocytes that failed fertilization

子宫内膜异位症相关的生育能力低下改变了卵丘细胞的微小RNA特征，并在未能受精的卵母细胞中表现出特别显著的影响。

Biological Research
IF4.6
2025-10-030
OAAI
Carmen Almiñana; Sofia Makieva; Stefan Bauersachs; Mara D. Saenz-de-Juano; Min Xie; Ana Velasco; Natalia Cervantes; Marianne R. Spalinger; Susanne E. Ulbrich; Brigitte Leeners
Unraveling the Converging Roles of ASC-Dependent Inflammasomes, Interleukin-1 Superfamily Members, Serum Amyloid A, and Non-Sterile Inflammation in Disease Pathology and Fibrosis in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis

阐明ASC依赖性炎症小体、白细胞介素-1超家族成员、血清淀粉样蛋白A及无菌性炎症在炎症性肠病和原发性硬化性胆管炎的疾病病理和纤维化中的汇聚作用。

International Journal of Molecular Sciences 2025, Vol. 26, Page 8042
IF4.9
2025-08-200
PRE
Marco Losa; Marlene Schwarzfischer; Marc Emmenegger; Marianne R. Spalinger; Gerhard Rogler; Michael Scharl
Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging

肠道菌群依赖性苯乙酸增加诱导衰老过程中的内皮细胞衰老

NATURE AGING
IF19.4
2025-05-120
OA
Saeedi Saravi, Seyed Soheil; Pugin, Benoit; Constancias, Florentin; Shabanian, Khatereh; Spalinger, Marianne; Le Gludic, Sylvain; Shabanian, Taraneh; Karsai, Gergely; Colucci, Manuel; Menni, Cristina; Attaye, Ilias; Zhang, Xinyuan; Allemann, Meret Sarah; Lee, Pratintip; Visconti, Alessia; Falchi, Mario; Alimonti, Andrea; Ruschitzka, Frank; Paneni, Francesco; Beer, Juerg H.
Intestinal epithelial PTPN23 is essential for gut barrier integrity and prevention of fatal bacterial translocation
JOURNAL OF CROHNS & COLITIS
IF8.7
2025-01-280
PRE
Alvarez, Rocio Sanchez; Montalban-Arques, Ana; Morsy, Yasser; Gottier, Claudia; Hafliger, Janine; Atrott, Kirstin; Bircher, Anna; Katkeviciute, Egle; Pohlmann, Doris; Linzmeier, Luise; Determann, Madita; Mamie, Celine; Niechcial, Anna; Schwarzfischer, Marlene; Zeissig, Sebastian; Lang, Silvia; Scharl, Michael; Spalinger, Marianne
Impact of Nanoplastic Particles on Macrophage Inflammation and Intestinal Health in a Mouse Model of Inflammatory Bowel Disease

纳米塑料颗粒对炎症性肠病小鼠巨噬细胞炎症和肠道健康的影响

NANOMATERIALS
IF4.3
2024-08-152
OAAI
Schwarzfischer, Marlene; Ruoss, Tano S.; Niechcial, Anna; Lee, Sung Sik; Wawrzyniak, Marcin; Laimbacher, Andrea; Atrott, Kirstin; Manzini, Roberto; Wilmink, Marijn; Linzmeier, Luise; Morsy, Yasser; Lang, Silvia; Rogler, Gerhard; Kaegi, Ralf; Scharl, Michael; Spalinger, Marianne R.
Discovery of potent and selective inhibitors of the protein tyrosine phosphatases PTPN2 and PTPN1 to trigger anti-tumor immunity through sensitization of tumor cells and activation of immune cells
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Pervolaraki, Kalliopi; Katkeviciute, Egle; Lambin, Dominique; Boland, Sandro; Kilonda, Amuri; Pericolle, Vincent; Nijs, Marnik; Haeck, Wanda; Metzger, Kristine; Klaassen, Hugo; Marchand, Arnaud; Chaltin, Patrick; Versele, Matthias; Spalinger, Marianne; Scharl, Michael
Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP)

共同培养是一种强大的功能设计合成联合体作为活生物治疗产品 (LBP) 的强大方法

GUT MICROBES
IF11
2023-02-168
OAAI
Kurt, Fabienne; Leventhal, Gabriel E.; Spalinger, Marianne Rebecca; Anthamatten, Laura; von Bieberstein, Philipp Rogalla; Menzi, Carmen; Reichlin, Markus; Meola, Marco; Rosenthal, Florian; Rogler, Gerhard; Lacroix, Christophe; de Wouters, Tomas
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 (vol 126, 1783, 2016)
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-02-155
OAAI
Spalinger, Marianne R.; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R.; Scharl, Sylvie; Gutte, Petrus M.; Gruetter, Markus G.; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C.; Dai, Xuezhi; Rawlings, David J.; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael

研究方向

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M
Michael Scharl
H 指数:60论文数:519被引数:2.5万
G
Gerhard Rogler
H 指数:97论文数:1,360被引数:4.2万
K
Kirstin Atrott
H 指数:27论文数:144被引数:2,529
C
Claudia Gottier
H 指数:12论文数:54被引数:1,038
S
Silvia Lang
H 指数:0论文数:2被引数:20
M
Marlene Schwarzfischer
H 指数:11论文数:58被引数:657
D
Declan F. McCole
H 指数:34论文数:186被引数:3,634
A
Ali Shawki
H 指数:18论文数:83被引数:2,002
I
Isabelle Frey‐Wagner
H 指数:22论文数:92被引数:1,923
A
Alina N. Santos
H 指数:8论文数:39被引数:351