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Improved Antitumor Activity of Interleukin-12-Secreting Chimeric Antigen Receptor T Cells Targeting CD176 across Different Carcinomas 靶向CD176的分泌白细胞介素-12的嵌合抗原受体T细胞在不同癌瘤中的抗肿瘤活性增强 Umland, Melina; Dragon, Anna Christina; Beermann, Luca Marie; Bonifacius, Agnes; Kehler, Patrik; Gellert, Johanna; Blasczyk, Rainer; Abken, Hinrich; Schambach, Axel; Hudecek, Michael; Eiz-Vesper, Britta 分享 收藏
In Remembrance of Professor Zelig Eshhar: A Life Committed to CAR-T 缅怀泽利格·埃什哈教授：一位致力于CAR-T的一生 Debets, Reno; Hawkins, Robert; Gilham, David; Gorochov, Guy; Schumacher, Ton; Uckert, Wolfgang; Blankenstein, Thomas; Crawford, Dorothy; Taylor, Naomi; Szollosi, Janos; Stauss, Hans; Mondino, Anna; Allavena, Paola; Alarcon, Balbino; Buning, Hildegard; Abken, Hinrich 分享 收藏
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LMP2A-Targeting CAR-T Cells Equipped With Inducible IL-18 to Address EBV-Associated Malignancies LMP2A靶向CAR-T细胞，配备可诱导型IL-18，以应对EBV相关恶性肿瘤 Dragon, Anna Christina; Thoelke, Stefanie; Mausberg, Philip; Zimmermann, Katharina; Blasczyk, Rainer; Hudecek, Michael; Abken, Hinrich; Schambach, Axel; Maecker-Kolhoff, Britta; Eiz-Vesper, Britta 分享 收藏
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Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function 整合结合亲和力和滋补信号可以为增强的T细胞功能提供合理的CAR设计 Barden, Markus; Elsenbroich, Patrick Ronan; Haas, Vivian; Ertelt, Moritz; Pervan, Philip; Velas, Lukas; Gergely, Bence; Szoeor, Arpad; Harrer, Dennis Christoph; Bezler, Valerie; Holzinger, Astrid; Friis, Rasmus Ulslev Wegener; Vereb, Gyorgy; Schuetz, Gerhard J.; Schoeder, Clara T.; Hombach, Andreas A.; Abken, Hinrich 分享 收藏
°Automated manufacturing and characterization of clinical grade autologous CD20 CAR T cells for the treatment of patients with stage III/IV melanoma Aleksandrova, Krasimira; Leise, Jana; Priesner, Christoph; Aktas, Murat; Apel, Michael; Assenmacher, Mario; Buerger, Iris; Richter, Anne; Altefrohne, Pia; Schubert, Christine; Holzinger, Astrid; Barden, Markus; Bezler, Valerie; von Bergwelt-Baildon, Michael; Borchmann, Peter; Goudeva, Lilia; Glienke, Wolfgang; Arseniev, Lubomir; Esser, Ruth; Abken, Hinrich; Koehl, Ulrike 分享 收藏
Preclinical development of CAR T cells with antigen-inducible IL-18 enforcement to treat GD2-positive solid cancers Fischer-Riepe, Lena; Kailayangiri, Sareetha; Zimmermann, Katharina; Pfeifer, Rita; Aigner, Michael; Altvater, Bianca; Kretschmann, Sascha; Voelkl, Simon; Hartley, Jordan; Dreger, Celine; Petry, Katja; Bosio, Andreas; von Doellen, Angelika; Hartmann, Wolfgang; Lode, Holger; Goerlich, Dennis; Mackensen, Andreas; Jungblut, Melanie; Schambach, Axel; Abken, Hinrich; Rossig, Claudia 分享 收藏
The effector program of human CD8 T cells supports tissue remodeling Delacher, Michael; Schmidleithner, Lisa; Simon, Malte; Stueve, Philipp; Sanderink, Lieke; Hotz-Wagenblatt, Agnes; Wuttke, Marina; Schambeck, Kathrin; Ruhland, Brigitte; Hofmann, Veronika; Bittner, Sebastian; Ritter, Uwe; Pant, Asmita; Helbich, Sara Salome; Voss, Morten; Lemmermann, Niels A.; Bessiri-Schake, Lisa; Bohn, Toszka; Eigenberger, Andreas; Menevse, Ayse Nur; Gebhard, Claudia; Strieder, Nicholas; Abken, Hinrich; Rehli, Michael; Huehn, Jochen; Beckhove, Philipp; Hehlgans, Thomas; Junger, Henrik; Geissler, Edward K.; Prantl, Lukas; Werner, Jens M.; Schmidl, Christian; Brors, Benedikt; Imbusch, Charles D.; Feuerer, Markus 分享 收藏
Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells 使用AND-门控衔接子RevCAR T细胞靶向结直肠癌细胞 Soto, Karla E. G.; Loureiro, Liliana R.; Bartsch, Tabea; Arndt, Claudia; Kegler, Alexandra; Mitwasi, Nicola; Drewitz, Laura; Hoffmann, Lydia; Saleh, Haidy A.; Crespo, Eugenia; Mehnert, Maria; Daglar, Cansu; Abken, Hinrich; Momburg, Frank; Bachmann, Michael; Feldmann, Anja 分享 收藏
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CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma Ciulean, Ioana Sonya; Fischer, Joe; Quaiser, Andrea; Bach, Christoph; Abken, Hinrich; Tretbar, Uta Sandy; Fricke, Stephan; Koehl, Ulrike; Schmiedel, Dominik; Grunwald, Thomas 分享 收藏
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process CAR T细胞作为抗实体癌的微药物: 在一步工程过程中将效应T细胞介导的细胞死亡与血管靶向相结合 Altvater, Bianca; Kailayangiri, Sareetha; Spurny, Christian; Fluegge, Maike; Meltzer, Jutta; Greune, Lea; Urban, Katja; Schwoeppe, Christian; Brand, Caroline; Schliemann, Christoph; Hintelmann, Heike; Harrach, Saliha; Hartmann, Wolfgang; Abken, Hinrich; Kuehle, Johannes; Schambach, Axel; Goerlich, Dennis; Berdel, Wolfgang E.; Rossig, Claudia 分享 收藏
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CAR T cells as micropharmacies to induce locoregional tumor vascular infarction by antigen-specific delivery of tissue factor to the tumor microenvironment Car-t细胞作为微药物通过抗原特异性递送组织因子到肿瘤微环境诱导局部区域肿瘤血管梗塞 Altvater, Bianca; Kailayangiri, Sareetha; Spurny, Christian; Flugge, Maike; Meltzer, Jutta; Greune, Lea; Schwoppe, Christian; Brand, Caroline; Schliemann, Christoph; Hartmann, Wolfgang; Abken, Hinrich; Schambach, Axel; Farwick, Nicole; Berdel, Wolfgang E.; Rossig, Claudia 分享 收藏
CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation Barden, Markus; Holzinger, Astrid; Velas, Lukas; Mezosi-Csaplar, Marianna; Szoeor, Arpad; Vereb, Gyoergy; Schuetz, Gerhard J.; Hombach, Andreas A.; Abken, Hinrich 分享 收藏
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