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Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State PTEN的Plk1磷酸化导致促进肿瘤的代谢状态 Li, Zhiguo; Li, Jie; Bi, Pengpeng; Lu, Ying; Burcham, Grant; Elzey, Bennett D.; Ratliff, Timothy; Konieczny, Stephen F.; Ahmad, Nihal; Kuang, Shihuan; Liu, Xiaoqi 分享 收藏
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MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response Hess, David A.; Strelau, Katherine M.; Karki, Anju; Jiang, Mei; Azevedo-Pouly, Ana C.; Lee, Ann-Hwee; Deering, Tye G.; Hoang, Chinh Q.; MacDonald, Raymond J.; Konieczny, Stephen F. 分享 收藏
The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells Xbp1-regulated转录因子Mist1通过抑制浆细胞Blimp1表达来限制抗体分泌 Woehner, Miriam; Pinter, Theresa; Boenelt, Peter; Hagelkruys, Astrid; Kostanova-Poliakova, Daniela; Stadlmann, Johannes; Konieczny, Stephen F.; Fischer, Maria; Jaritz, Markus; Busslinger, Meinrad 分享 收藏
Targeting Plk1 Sensitizes Pancreatic Cancer to Immune Checkpoint Therapy Zhang, Zhuangzhuang; Cheng, Lijun; Li, Jie; Qiao, Qi; Karki, Anju; Allison, Derek B.; Shaker, Nuha; Li, Kunyu; Utturkar, Sagar M.; Lanman, Nadia M. Atallah; Rao, Xiongjian; Rychahou, Piotr; He, Daheng; Konieczny, Stephen F.; Wang, Chi; Shao, Qing; Evers, B. Mark; Liu, Xiaoqi 分享 收藏
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Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment Schweickert, Patrick G.; Yang, Yi; White, Emily E.; Cresswell, Gregory M.; Elzey, Bennett D.; Ratliff, Timothy L.; Arumugam, Paritha; Antoniak, Silvio; Mackman, Nigel; Flick, Matthew J.; Konieczny, Stephen F. 分享 收藏
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Thrombin Signaling Promotes Pancreatic Adenocarcinoma through PAR-1-Dependent Immune Evasion Yang, Yi; Stange, Amanda; Schweickert, Patrick G.; Lanman, Nadia A.; Paul, Erin N.; Monia, Brett P.; Revenko, Alexey S.; Palumbo, Joseph S.; Mullins, Eric S.; Elzey, Bennett D.; Janssen, Edith M.; Konieczny, Stephen F.; Flick, Matthew J. 分享 收藏
Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer Shouksmith, Andrew E.; Shah, Fenil; Grimard, Michelle L.; Gawel, Justyna M.; Raouf, Yasir S.; Geletu, Mulu; Berger-Becvar, Angelika; de Araujo, Elvin D.; Luchman, H. Artee; Heaton, William L.; Bakhshinyan, David; Adile, Ashley A.; Venugopal, Chitra; O'Hare, Thomas; Deininger, Michael W.; Singh, Sheila K.; Konieczny, Stephen F.; Weiss, Samuel; Fishel, Melissa L.; Gunning, Patrick T. 分享 收藏
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth 基质hedgehog信号的破坏启动PTEN的RNF5-mediated蛋白酶体降解并加速胰腺肿瘤的生长 Pitarresi, Jason R.; Liu, Xin; Avendano, Alex; Thies, Katie A.; Sizemore, Gina M.; Hammer, Anisha M.; Hildreth, Blake E., III; Wang, David J.; Steck, Sarah A.; Donohue, Sydney; Cuitino, Maria C.; Kladney, Raleigh D.; Mace, Thomas A.; Chang, Jonathan J.; Ennis, Christina S.; Li, Huiqing; Reeves, Roger H.; Blackshaw, Seth; Zhang, Jianying; Yu, Lianbo; Fernandez, Soledad A.; Frankel, Wendy L.; Bloomston, Mark; Rosol, Thomas J.; Lesinski, Gregory B.; Konieczny, Stephen F.; Guttridge, Denis C.; Rustgi, Anil K.; Leone, Gustavo; Song, Jonathan W.; Wu, Jinghai; Ostrowski, Michael C. 分享 收藏
Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment Jakubison, Brad L.; Schweickert, Patrick G.; Moser, Sarah E.; Yang, Yi; Gao, Hongyu; Scully, Kathleen; Itkin-Ansari, Pamela; Liu, Yunlong; Konieczny, Stephen F. 分享 收藏
Molecular and phenotypic profiling of pancreatic cancer cachexia in novel murine models and patients Zimmers, Teresa A.; Jiang, Yanlin; Liu, Jianguo; Ceppa, Eugene; Nakeeb, Atilla; House, Michael; Zyromski, Nicholas; Schmidt, C. Max; Hannaford, Katharyn; Schloss, Daniel; Brooks, Cynthia; Radovich, Milan; Lui, Yunlong; Jiang, Guanglong; Konieczny, Stephen F.; Schweickert, Patrick; Hancock, Brad; Kayes, Joshua; Zhong, Xiaoling; Poirier, Christophe; Au, Ernie; Bonetto, Andrea; Shahda, Safi; Kohli, Marc; O'Neil, Bert; Pons, Marianne; Koniaris, Leonidas 分享 收藏
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