William C. Wetsel - Publications, H-index & Citations

William C. Wetsel

Duke University Medical Center

72H指数

314论文数

1.9W被引数

收录论文 100

发表时间

Structure based discovery of antipsychotic-like TAAR1 agonists 基于结构的抗精神病样TAAR1激动剂的发现

Nature Communications

IF15.7

2026-09-17

OAAI

Sijie Huang; Heng Liu; Yujin Wu; Joao M. Braz; Divya Kranthi; Brendan W. Hall; Xinyue Zhang; Dmytro S. Radchenko; Yurii S. Moroz; John J. Irwin; Allan I. Basbaum; H. Eric Xu; William C. Wetsel; Brian K. Shoichet

A suite of engineered mice for interrogating psychedelic drug actions 一套用于探究迷幻药物作用机制的工程小鼠

Nature Neuroscience

IF20

2026-08-06

OAAI

Yi-Ting Chiu; Ariel Y. Deutch; Wei Wang; Gavin P. Schmitz; Karen Lu Huang; D. Dewran Kocak; Pierre Llorach; Kasey R. Bowyer; Bei Liu; Noah Sciaky; Kunjie Hua; Chongguang Chen; Sarah E. Mott; Jesse Niehaus; Jeffrey F. DiBerto; Justin English; Jessica J. Walsh; Grégory Scherrer; Melissa A. Herman; Zhuhao Wu; William C. Wetsel; Bryan L. Roth

A cholinergic hub in the nucleus accumbens gates opioid-reward learning 伏隔核中的胆碱能中枢调控阿片类药物介导的奖赏学习

Nature

IF48.5

2026-08-05

PREAI

S. Aryana Yousefzadeh; Haidun Yan; Seung-Hwa Kwak; Yunju Oh; Pyeonghwa Jeong; Vladimir Pogorelov; J. Russell Ravenel; Shaun S. X. Lim; James M. Roach; Brenda C. Shields; Ramona M. Rodriguiz; William C. Wetsel; Jiyong Hong; Michael R. Tadross

Structure-guided Discovery of Non-catechol Dopamine D1 Receptor Ligands with Biased Agonism and Antagonism 基于结构的非儿茶酚多巴胺D1受体配体的发现：具有偏向性激动和拮抗作用

Journal of Biological Chemistry

IF3.9

2026-04-27

OAAI

Yang Zhou; William C. Wetsel; Alem W. Kahsai; Steven H. Olson; Lawrence S. Barak

Perinatal exposure to perfluoroalkyl substances impairs maternal care and induces depressive-like behavior in mice 围产期暴露于全氟烷基物质会损害母性行为并诱导小鼠产生抑郁样行为

TOXICOLOGICAL SCIENCES

IF4.1

2025-11-01

PREAI

Rawtani, Harshal; Mellouk, Namya; Jackson, Julia; Lee, Chia-ying; Rodriguiz, Ramona M.; Wetsel, William C.; Feng, Liping

Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain 神经肽素受体1的Arrestin偏向性别构调节剂缓解急性和慢性疼痛

Cell

IF42.5

2025-05-19

PREAI

Ran Guo; Ouyang Chen; Yang Zhou; Sangsu Bang; Sharat Chandra; Yize Li; Gang Chen; Rou-Gang Xie; Wei He; Jing Xu; Richard Zhou; Shaoyong Song; Kelsey L. Person; Madelyn N. Moore; Abigail R. Alwin; Ivan Spasojevic; Michael R. Jackson; Steven H. Olson; Marc G. Caron; Lauren M. Slosky; William C. Wetsel; Lawrence S. Barak; Ru-Rong Ji

Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl 两剂Qβ病毒样颗粒疫苗可诱导产生针对海洛因和芬太尼的保护性抗体。

NPJ VACCINES

IF6.5

2025-03-28

OAAI

Romano, Isabella G.; Johnson-Weaver, Brandi; Core, Susan B.; Jamus, Andzoa N.; Brackeen, Marcus; Blough, Bruce; Dey, Subhakar; Huang, Yumei; Staats, Herman; Wetsel, William C.; Chackerian, Bryce; Frietze, Kathryn M.

Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions 天然蛋白质组的邻近性分析揭示了自闭症和相关神经发育状况小鼠模型中的表型修饰剂

NATURE COMMUNICATIONS

IF15.7

2024-08-09

OAAI

Gao, Yudong; Shonai, Daichi; Trn, Matthew; Zhao, Jieqing; Soderblom, Erik J.; Garcia-Moreno, S. Alexandra; Gersbach, Charles A.; Wetsel, William C.; Dawson, Geraldine; Velmeshev, Dmitry; Jiang, Yong-hui; Sloofman, Laura G.; Buxbaum, Joseph D.; Soderling, Scott H.

Presynaptic Rac1 in the hippocampus selectively regulates working memory 海马突触前Rac1选择性调节工作记忆

ELIFE

IF0

2024-07-24

OAAI

Kim, Jaebin; Bustamante, Edwin; Sotonyi, Peter; Maxwell, Nicholas; Parameswaran, Pooja; Kent, Julie K.; Wetsel, William C.; Soderblom, Erik J.; Racz, Bence; Soderling, Scott H.

The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice G蛋白偏向性5-羟色胺5-HT2A受体激动剂lisuride在小鼠中发挥抗抑郁药样活性

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-10-10

OAAI

Pogorelov, Vladimir M.; Rodriguiz, Ramona M.; Roth, Bryan L.; Wetsel, William C.

Rescue of glutaric aciduria type I in mice by liver- directed therapies

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-04-19

OAAI

Barzi, Mercedes; Johnson, Collin G.; Chen, Tong; Rodriguiz, Ramona M.; Hemmingsen, Madeline; Gonzalez, Trevor J.; Rosales, Alan; Beasley, James; Peck, Cheryl K.; Ma, Yunhan; Stiles, Ashlee R.; Wood, Timothy C.; Maeso-Diaz, Raquel; Diehl, Anna Mae; Young, Sarah P.; Everitt, Jeffrey I.; Wetsel, William C.; Lagor, William R.; Bissig-Choisat, Beatrice; Asokan, Aravind; El-Gharbawy, Areeg; Bissig, Karl-Dimiter

Abi2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

139

OAAI

Grove, M; Demyanenko, G; Echarri, A; Zipfel, PA; Quiroz, ME; Rodriguiz, RM; Playford, M; Martensen, SA; Robinson, MR; Wetsel, WC; Maness, PF; Pendergast, AM

Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Quan, H; Athirakul, K; Wetsel, WC; Torres, GE; Stevens, R; Chen, YT; Coffman, TM; Caron, MG

Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice

COMMUNICATIONS BIOLOGY

IF5.1

2023-03-09

OAAI

Wang, Zhuoran; Li, Qiang; Kolls, Brad J. J.; Mace, Brian; Yu, Shu; Li, Xuan; Liu, Wei; Chaparro, Eduardo; Shen, Yuntian; Dang, Lihong; del Aguila, Angela; Bernstock, Joshua D. D.; Johnson, Kory R. R.; Yao, Junjie; Wetsel, William C. C.; Moore, Scott D. D.; Turner, Dennis A. A.; Yang, Wei

RESCUE OF GLUTARIC ACIDURIA TYPE I MICE BY LIVER DIRECTED THERAPIES

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-03-01

PREAI

Barzi, Mercedes; Johnson, Collin; Chen, Tong; Rodriguiz, Ramona; Hemmingsen, Madeline; Gonzalez, Trevor J.; Rosales, Alan; Beasley, James; Ma, Yunhan; Stiles, Ashlee R.; Wood, Timothy C.; Maeso-Diaz, Raquel; Diehl, Ana Mae; Young, Sarah P.; Everitt, Jeffrey I.; Wetsel, William C.; Bissig-Choisat, Beatrice; Asokan, Aravind; El-Gharbawy, Areeg; Bissig, Karl-Dimiter

Protective effects of omega-3 fatty acids in a blood-brain barrier-on- chip model and on postoperative delirium-like behaviour in mice omega-3脂肪酸在血脑屏障芯片模型和小鼠术后谵妄样行为中的保护作用

BRITISH JOURNAL OF ANAESTHESIA

IF9.2

2023-02-01

OAAI

Yang, Ting; Velagapudi, Ravikanth; Kong, Cuicui; Ko, Unghyeon; Kumar, Vardhman; Brown, Paris; Franklin, Nathan O.; Zhang, Xiaobei; Caceres, Ana I.; Min, Hyunjung; Filiano, Anthony J.; Rodriguiz, Ramona M.; Wetsel, William C.; Varghese, Shyni; Terrando, Niccolo

Establishment of multi-stage intravenous self-administration paradigms in mice

SCIENTIFIC REPORTS

IF3.9

2022-12-11

OAAI

Slosky, Lauren M. M.; Pires, Andrea; Bai, Yushi; Clark, Nicholas B. B.; Hauser, Elizabeth R. R.; Gross, Joshua D. D.; Porkka, Fiona; Zhou, Yang; Chen, Xiaoxiao; Pogorelov, Vladimir M. M.; Toth, Krisztian; Wetsel, William C. C.; Barak, Lawrence S. S.; Caron, Marc G. G.

Conserved YKL-40 changes in mice and humans after postoperative delirium

brain behavior and immunity

IF0

2022-12-01

OAAI

David-Bercholz, Jennifer; Acker, Leah; Caceres, Ana I.; Wu, Pau Yen; Goenka, Saanvi; Franklin, Nathan O.; Rodriguiz, Ramona M.; Wetsel, William C.; Devinney, Michael; Wright, Mary Cooter; Zetterberg, Henrik; Yang, Ting; Berger, Miles; Terrando, Niccolo

Characterization and Chemical Optimization of the D2 Dopamine Receptor-Selective Antagonist, ML321, Identifies Lead Compounds for the Clinical Treatment of Neuropsychiatric Disorders

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Nilson, Ashley N.; Garcia, Andres Dulcey; Free, R. B.; Boldizsar, Noelia; Pearlstein, Hannah; Rocereta, Julia A.; Rodriguiz, Ramona M.; Lane, J. R.; Lee, Kuo H.; Shi, Lei; Wetsel, William C.; Marugan, Juan J.; Sibley, David R.

Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-06

OAAI

Zhang, Zhiquan; Ma, Qing; Velagapudi, Ravikanth; Barclay, William E.; Rodriguiz, Ramona M.; Wetsel, William C.; Yang, Ting; Shinohara, Mari L.; Terrando, Niccolo

研究方向