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Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W Bustillos, Bernardo A.; Cocker, Liam T.; Coban, Mathew A.; Weber, Caleb A.; Bredenberg, Jenny M.; Boneski, Paige K.; Siuda, Joanna; Slawek, Jaroslaw; Puschmann, Andreas; Narendra, Derek P.; Graff-Radford, Neill R.; Wszolek, Zbigniew K.; Dickson, Dennis W.; Ross, Owen A.; Caulfield, Thomas R.; Springer, Wolfdieter; Fiesel, Fabienne C. 分享 收藏
Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs Jin, Yunjung; Li, Fuyao; Li, Zonghua; Ikezu, Tadafumi C.; O'Leary, Justin; Selvaraj, Manikandan; Zhu, Yiyang; Martens, Yuka A.; Koga, Shunsuke; Santhakumar, Hannah; Li, Yonghe; Lu, Wenyan; You, Yang; Lolo, Kiara; Deture, Michael; Beasley, Alexandra I.; Davis, Mary D.; Mclean, Pamela J.; Ross, Owen A.; Kanekiyo, Takahisa; Ikezu, Tsuneya; Caulfield, Thomas; Carr, Jonathan; Wszolek, Zbigniew K.; Bu, Guojun; Dickson, Dennis W.; Zhao, Na 分享 收藏
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (vol 19, 29, 2024) Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; DeTure, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjorn; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard 分享 收藏
A novel histone deacetylase inhibitor W2A-16 improves the barrier integrity in brain vascular endothelial cells Inoue, Yasuteru; Ren, Yingxue; Zhang, Shuwen; Bamkole, Michael; Islam, Naeyma N.; Selvaraj, Manikandan; Lu, Wenyan; Caulfield, Thomas R.; Li, Yonghe; Kanekiyo, Takahisa 分享 收藏
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Decoding Immuno-Competence: A Novel Analysis of Complete Blood Cell Count Data in COVID-19 Outcomes Kempaiah, Prakasha; Libertin, Claudia R.; Chitale, Rohit A.; Naeyma, Islam; Pleqi, Vasili; Sheele, Johnathan M.; Iandiorio, Michelle J.; Hoogesteijn, Almira L.; Caulfield, Thomas R.; Rivas, Ariel L. 分享 收藏
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; Deture, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjoern; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard 分享 收藏
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Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics Gupta, Yash; Savytskyi, Oleksandr, V; Coban, Matt; Venugopal, Amoghavarsha; Pleqi, Vasili; Weber, Caleb A.; Chitale, Rohit; Durvasula, Ravi; Hopkins, Christopher; Kempaiah, Prakasha; Caulfield, Thomas R. 分享 收藏
Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase Deletti, Garrett; Green, Sajan D. D.; Weber, Caleb; Patterson, Kristen N. N.; Joshi, Swapnil S. S.; Khopade, Tushar M. M.; Coban, Mathew; Veek-Wilson, James; Caulfield, Thomas R. R.; Viswanathan, Rajesh; Lane, Amy L. L. 分享 收藏
Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14 Hayun, Hezi; Coban, Matt; Bhagat, Ashok Kumar; Ozer, Eden; Alfonta, Lital; Caulfield, Thomas R.; Radisky, Evette S.; Papo, Niv 分享 收藏
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover Fiesel, Fabienne C.; Fricova, Dominika; Hayes, Caleb S.; Coban, Mathew A.; Hudec, Roman; Bredenberg, Jenny M.; Broadway, Benjamin J.; Markham, Briana N.; Yan, Tingxiang; Boneski, Paige K.; Fiorino, Gabriella; Watzlawik, Jens O.; Hou, Xu; McCarty, Arthur M.; Lewis-Tuffin, Laura J.; Zhong, Jun; Madden, Benjamin J.; Ordureau, Alban; An, Heeseon; Puschmann, Andreas; Wszolek, Zbigniew K.; Ross, Owen A.; Harper, J. Wade; Caulfield, Thomas R.; Springer, Wolfdieter 分享 收藏
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APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia Liu, Chia-Chen; Murray, Melissa E.; Li, Xia; Zhao, Na; Wang, Na; Heckman, Michael G.; Shue, Francis; Martens, Yuka; Li, Yonghe; Raulin, Ana-Caroline; Rosenberg, Cassandra L.; Doss, Sydney, V; Zhao, Jing; Wren, Melissa C.; Jia, Lin; Ren, Yingxue; Ikezu, Tadafumi C.; Lu, Wenyan; Fu, Yuan; Caulfield, Thomas; Trottier, Zachary A.; Knight, Joshua; Chen, Yixing; Linares, Cynthia; Wang, Xue; Kurti, Aishe; Asmann, Yan W.; Wszolek, Zbigniew K.; Smith, Glenn E.; Vemuri, Prashanthi; Kantarci, Kejal; Knopman, David S.; Lowe, Val J.; Jack, Clifford R. Jr Jr; Parisi, Joseph E.; Ferman, Tanis J.; Boeve, Bradley F.; Graff-Radford, Neill R.; Petersen, Ronald C.; Younkin, Steven G.; Fryer, John D.; Wang, Hu; Han, Xianlin; Frieden, Carl; Dickson, Dennis W.; Ross, Owen A.; Bu, Guojun 分享 收藏
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An activating germline IDH1 variant associated with a tumor entity characterized by unilateral and bilateral chondrosarcoma of the mastoid Blackburn, Patrick R.; Carter, Jodi M.; Oglesbee, Devin; Westendorf, Jennifer J.; Neff, Brian A.; Stichel, Damian; Tsen, David W.; Gavrilova, Ralitza H.; Wesseling, Pieter; von Deimling, Andreas; Caulfield, Thomas R.; Klee, Eric W.; Pusch, Stefan; Inwards, Carrie Y. 分享 收藏
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