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F

Francisco León

University of South Carolina

43H指数
221论文数
6.1K被引数
收录论文 90
发表时间
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Jacareubin Derivatives Increase Their Anti-Allergic ActivityJacareubin衍生物增强其抗过敏活性
errMolecules
IF4.6
err2026-05-15
err0
errOAAI
errRosario Tavera-Hernández; Jesabel Pérez-Rodríguez; Antonio Nieto-Camacho; Omar Noel Medina-Campos; José Pedraza-Chaverri; Francisco León; Claudia González-Espinosa; Manuel Jiménez-Estrada; Ricardo Reyes-Chilpa; Jorge Ivan Castillo-Arellano
err分享
err收藏
Design and Semisynthesis of Aminocannabinoids as Neurological Magic Shotguns氨基大麻素的分子设计及半合成研究：靶向神经系统的精准递送技术
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2025-12-01
err0
PREAI
errStryker, Zachary; Cutler, Stephen J.; Francis, T. Chase; Leon, Francisco
err分享
err收藏
Dillapiole Dampens the Expression of the Major Virulence Genes of Francisella tularensis二氢欧山芹醇能降低弗朗西斯·土拉杆菌主要毒力基因的表达。
errMolecules 2025, Vol. 30, Page 3995
IF4.6
err2025-10-06
err0
errOAAI
errElliot M. Collins; Anthony Sako; Kristen Sikorsky; James Denvir; Jun Fan; Donald A. Primerano; Deanna M. Schmitt; Stuart Cantlay; Roger Seeber; Francisco León; Joseph Horzempa
err分享
err收藏
From Kratom to Semi-Synthetic Opioids: The Rise and Risks of MGM-15从 kratom 到半合成阿片类药物：MGM-15 的兴起与风险
errDRUG TESTING AND ANALYSIS
IF2.7
err2025-09-01
err1
PREAI
errGour, Abhishek; Mukhopadhyay, Sushobhan; Henderson, Allison; Awad, Ahmed; Seabra, Maria A.; Pullman, Mallory; Leon, Francisco; Cutler, Stephen J.; McCurdy, Christopher R.; Sharma, Abhisheak
err分享
err收藏
Cardio-pulmonary arrest in a patient revived with naloxone following reported use of 7-hydroxymitragynine在使用7-羟基 Mitragynine 后，一名患者出现心肺骤停，随后通过纳洛酮（naloxone）成功复苏。
errCLINICAL TOXICOLOGY
IF3.3
err2025-09-01
err1
PREAI
errPullman, Mallory K.; Kanumuri, Siva Rama Raju; Leon, Juan Francisco; Cutler, Stephen J.; Mccurdy, Christopher R.; Sharma, Abhisheak
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err收藏
Uncaria attenuata and its main corynanthean alkaloid, villocarine A, exert antinociceptive effects in rats via activation of central μ-opioid receptors钩藤属植物 Uncaria attenuata 及其主要的考尼他品烷类生物碱 villocarine A，通过激活中枢 μ-阿片受体在大鼠中发挥镇痛作用。
errJournal of Ethnopharmacology
IF5.4
err2025-08-14
err0
PREAI
errTan Ai Fein Ching-Ga; Nelson Jeng-Yeou Chear; Mohamad Anuar Ahad; Boon-Keat Khor; Francisco León; Abhisheak Sharma; Maria ABL. Seabra; Wen-Nee Tan; Zurina Hassan; Vikneswaran Murugaiyah; Christopher R. McCurdy; Surash Ramanathan
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Semi-Synthesis of Dimeric Cannabidiol Derivatives and Evaluation of their Affinity at Neurological Targets
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2025-01-24
err0
PREAI
errStryker, Zachary; Castillo-Arellano, Jorge I.; Cutler, Stephen J.; Wyatt, Michael D.; Leon, Francisco
err分享
err收藏
The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α 2 receptor activity in vitro and in vivoMitragyna speciosa (kratom) 生物碱mitragynine: 体外和体内肾上腺素能 α2受体活性分析
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2024-10-01
err2
errOAAI
errObeng, Samuel; Crowley, Morgan L.; Mottinelli, Marco; Leon, Francisco; Gonzalez, Julio D. Zuarth; Chen, Yiming; Gamez-Jimenez, Lea R.; Restrepo, Luis F.; Ho, Nicholas P.; Patel, Avi; Rocha, Joelma Martins; Alvarez, Manuel A.; Thadisetti, Amsha M.; Park, Chai R.; Pallares, Victoria L. C.; Milner, Megan J.; Canal, Clinton E.; Hampson, Aidan J.; McCurdy, Christopher R.; McMahon, Lance R.; Wilkerson, Jenny L.; Hiranita, Takato
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Synthesis and Monoamine Oxidase Inhibitory Activity of Halogenated Flavones
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-04-03
err0
PREAI
errCastillo-Arellano, Jorge I.; Stryker, Zachary; Wyatt, Michael D.; Leon, Francisco
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err收藏
Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine
errPLANTS-BASEL
IF4.1
err2023-11-15
err7
errOAAI
errLarit, Farida; Leon, Francisco
err分享
err收藏
Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in RatsS
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err5
errOAAI
errKamble, Shyam H.; Obeng, Samuel; Leon, Francisco; Restrepo, Luis F.; King, Tamara I.; Berthold, Erin C.; Kanumuri, Siva Rama Raju; Gamez-Jimenez, Lea R.; Pallares, Victoria L. C.; Patel, Avi; Ho, Nicholas P.; Hampson, Aidan; McCurdy, Christopher R.; McMahon, Lance R.; Wilkerson, Jenny L.; Sharma, Abhisheak; Hiranita, Takato
err分享
err收藏
The Polypharmacological Effects of Cannabidiol
errMOLECULES
IF4.6
err2023-04-06
err69
errOAAI
errCastillo-Arellano, Jorge; Canseco-Alba, Ana; Cutler, Stephen J.; Leon, Francisco
err分享
err收藏
Natural Corynanthe-Type Cholinesterase Inhibitors from Malaysian Uncaria attenuata Korth.: Isolation, Characterization, In Vitro and In Silico Studies来自马来西亚Uncaria的天然Corynanthe型胆碱酯酶抑制剂衰减Korth。: 隔离，表征，体外和计算机研究
errMETABOLITES
IF3.7
err2023-03-07
err1
errOAAI
errChear, Nelson Jeng-Yeou; Ching-Ga, Tan Ai Fein; Khaw, Kooi-Yeong; Leon, Francisco; Tan, Wen-Nee; Yusof, Siti R. R.; McCurdy, Christopher R. R.; Murugaiyah, Vikneswaran; Ramanathan, Surash
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Directed Biosynthesis of Mitragynine Stereoisomers
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-02-22
err19
errOAAI
errSchotte, Carsten; Jiang, Yindi; Grzech, Dagny; Dang, Thu-Thuy T.; Laforest, Larissa C.; Leon, Francisco; Mottinelli, Marco; Nadakuduti, Satya Swathi; McCurdy, Christopher R.; O'Connor, Sarah E.
err分享
err收藏
Interactive Effects of μ-Opioid and Adrenergic-α2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2022-12-01
err19
errOAAI
errObeng, Samuel; Leon, Francisco; Patel, Avi; Gonzalez, Julio D. Zuarth; Da Silva, Lucas Chaves; Restrepo, Luis F.; Gamez-Jimenez, Lea R.; Ho, Nicholas P.; Calvache, Maria P. Guerrero; Pallares, Victoria L. C.; Helmes, Justin A.; Shiomitsu, Sakura K.; Soto, Paul L.; Hampson, Aidan J.; McCurdy, Christopher R.; McMahon, Lance R.; Wilkerson, Jenny L.; Hiranita, Takato
err分享
err收藏
Metabolism of Speciociliatine, an Overlooked Kratom Alkaloid for its Potential Pharmacological Effects
errAAPS JOURNAL
IF3.7
err2022-07-19
err14
errOAAI
errKamble, Shyam H.; Berthold, Erin C.; Kanumuri, Siva Rama Raju; King, Tamara I.; Kuntz, Michelle A.; Leon, Francisco; Mottinelli, Marco; McMahon, Lance R.; McCurdy, Christopher R.; Sharma, Abhisheak
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Natural Products Inhibitors of Monoamine Oxidases-Potential New Drug Leads for Neuroprotection, Neurological Disorders, and Neuroblastoma
errMOLECULES
IF4.6
err2022-07-04
err44
errOAAI
errChaurasiya, Narayan D.; Leon, Francisco; Muhammad, Ilias; Tekwani, Babu L.
err分享
err收藏
Computationally Assisted Lead Optimization of Novel Potent and Selective MAO-B Inhibitors
errBIOMEDICINES
IF3.9
err2021-09-24
err7
errOAAI
errGogineni, Vedanjali; Nael, Manal A.; Chaurasiya, Narayan D.; Elokely, Khaled M.; McCurdy, Christopher R.; Rimoldi, John M.; Cutler, Stephen J.; Tekwani, Babu L.; Leon, Francisco
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Activity of Mitragyna speciosa (Kratom) Alkaloids at Serotonin Receptors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-09-01
err39
errOAAI
errLeon, Francisco; Obeng, Samuel; Mottinelli, Marco; Chen, Yiming; King, Tamara, I; Berthold, Erin C.; Kamble, Shyam H.; Restrepo, Luis F.; Patel, Avi; Gamez-Jimenez, Lea R.; Lopera-Londono, Carolina; Hiranita, Takato; Sharma, Abhisheak; Hampson, Aidan J.; Canal, Clinton E.; McMahon, Lance R.; McCurdy, Christopher R.
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Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery (vol 64, pg 6523, 2021)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-07-15
err0
PREAI
errObeng, Samuel; Hiranita, Takato; Leon, Francisco; McMahon, Lance R.; McCurdy, Christopher R.
err分享
err收藏

研究方向

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合作学者
合作期刊
J
Jean‐Frédéric Colombel
H 指数: 139 · 论文数: 1.4K
A
Akiko Iwasaki
H 指数: 124 · 论文数: 611
W
Warren Strober
H 指数: 123 · 论文数: 659
M
Michael L. Klein
H 指数: 120 · 论文数: 1.2K
R
Richard S. Blumberg
H 指数: 110 · 论文数: 552
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