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D

David W. Hein

school of medicine

59H指数
381论文数
1.5W被引数
收录论文 110
发表时间
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CRISPR/Cas9 knockout of N-acetyltransferase 1 influences mesenchymal transition in glioblastoma in a cell line dependent mannerCRISPR/Cas9敲除N-乙酰转移酶1以细胞系依赖方式影响胶质母细胞瘤的间充质转化
errJournal of Cancer Research and Clinical Oncology
IF2.8
err2026-08-24
err0
errOAAI
errLuke A. Schroeder; Mariam R. Habil; Hannah M. Newberry; Phoebe K. Dillon; James T. F. Wise; David W. Hein; Joshua L. Hood
err分享
err收藏
Hydralazine Effects on DNA Damage and Oxidative Stress Responses in Mammalian Cells and Human Hepatocytes肼屈嗪对哺乳动物细胞和人肝细胞的DNA损伤及氧化应激反应的影响
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errStephens, Makayla A.; Cass, Alexandra A.; Habil, Mariam R.; Hein, David
err分享
err收藏
Impact of N-Acetylation on DNA Damage and Oxidative Stress Responses in Mammalian Cells and Human Hepatocytes Treated with HydralazineN-乙酰化对羟嗪处理哺乳动物细胞和人肝细胞中DNA损伤及氧化应激反应的影响
errBiomolecules
IF4.8
err2026-04-10
err0
errOAAI
errMariam R. Habil; Makayla A. Stephens; Alexandra A. Cass; Elise M. Mittlestat; Darbie Kwon; Alexandra Ellison; J. Calvin Kouokam; David W. Hein
err分享
err收藏
Correction: Effect of N‑acetyltransferase 2 genetic polymorphism on 4,4′‑methylenebis(2‑chloroaniline)‑induced genotoxicity and oxidative stress更正：N‑acetyltransferase 2基因多态性对4,4′‑methylenebis(2‑chloroaniline)诱导的基因毒性及氧化应激的影响
errArchives of Toxicology
IF6.9
err2025-12-08
err0
errOAAI
errMariam R. Habil; Raúl A. Salazar‑González; Mark A. Doll; David W. Hein
err分享
err收藏
PharmVar GeneFocus: NAT2-Genetic Variation and Updated Nomenclature
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-12-01
err0
errOAAI
errPapanikolaou, Georgia; Poloni, Estella S.; Agundez, Jose A. G.; Teixeira, Raquel L. F.; Boone, Erin C.; Rezende Santos, Adalberto; Whirl-Carrillo, Michelle; Sangkuhl, Katrin; Klein, Teri E.; Habil, Mariam R.; Fakis, Giannoulis; Minchin, Rodney F.; Hein, David W.; Boukouvala, Sotiria; Gaedigk, Andrea
err分享
err收藏
Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy临床药理学实施协会指南：NAT2基因型与肼屈嗪疗法
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-09-01
err1
errOAAI
errEadon, Michael T.; Hein, David W.; Andersen, Michael A.; Chapman, Arlene B.; Cooper-DeHoff, Rhonda M.; Desta, Zeruesenay; Duarte, Julio D.; Elchynski, Amanda L.; Gaedigk, Andrea; Karol, Seth E.; Limdi, Nita A.; Lteif, Christelle; Sosinski, Laura; Zubiaur, Pablo; Whirl-Carrillo, Michelle; Klein, Teri E.; Caudle, Kelly E.; Donnelly, Roseann S.; Agundez, Jose A. G.
err分享
err收藏
Arylamine N-acetyltransferase 1 knockout in immortalized human bronchial cells results in a reduction of cellular growthArylamine N-acetyltransferase 1基因敲除在永生化的支气管细胞中导致细胞生长减少
errGENE REPORTS
IF0
err2025-09-01
err0
PREAI
errDiven, Sandra S.; Tarvestad-Laise, Kate; Hein, David W.; Wise, James T. F.
err分享
err收藏
Report on the 2024 international phase II/N-acetyltransferase workshop2024年国际II期/N-乙酰基转移酶研讨会报告
errArchives of Toxicology
IF6.9
err2025-08-30
err0
PREAI
errDavid W. Hein
err分享
err收藏
Mini-review: Human N-acetyltransferase genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity微型综述：人类N-乙酰转移酶遗传多态性与芳胺和烷基苯胺遗传毒性的易感性
errpharmacology and experimental therapeutics
IF0
err2025-07-28
err0
errOAAI
errMariam R. Habil; David W. Hein
err分享
err收藏
Metabolism and genotoxicity of 4,4'-oxydianiline is dependent on N-acetyltransferase 2 genetic polymorphism4,4'-oxydianiline的代谢和遗传毒性依赖于N-乙酰转移酶2基因多态性
errENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
IF4.2
err2025-06-01
err0
PREAI
errSalazar-Gonzalez, Raul A.; Wise, James T. F.; Doll, Mark A.; Hein, David W.
err分享
err收藏
Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline由3,4-二甲基苯胺诱导的生物活化、致突变性、DNA损伤和氧化应激
errBIOMOLECULES
IF4.8
err2024-12-07
err0
errOAAI
errHabil, Mariam R.; Salazar-Gonzalez, Raul A.; Doll, Mark A.; Hein, David W.
err分享
err收藏
Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes
errCARDIOVASCULAR TOXICOLOGY
IF3.7
err2024-06-08
err0
PREAI
errWalls, Kennedy M.; Joh, Jonathan Y.; Hong, Kyung U.; Hein, David W.
err分享
err收藏
Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes (vol 97, pg 1613, 2023)
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-09-04
err0
errOAAI
errWalls, Kennedy M.; Hong, Kyung U.; Hein, David W.
err分享
err收藏
The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-08-18
err0
PREAI
errHein, David W. W.; Salazar-Gonzalez, Raul A.; Doll, Mark A. A.; Zang, Yu
err分享
err收藏
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-05-04
err2
errOAAI
errHabil, Mariam R.; Salazar-Gonzalez, Raul A.; Doll, Mark A.; Hein, David W.
err分享
err收藏
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-04-25
err3
errOAAI
errHabil, Mariam R.; Hein, David W.
err分享
err收藏
Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-04-02
err6
PREAI
errWalls, Kennedy M.; Hong, Kyung U.; Hein, David W.
err分享
err收藏
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines
errTOXICOLOGICAL SCIENCES
IF4.1
err2022-09-26
err9
errOAAI
errHong, Kyung U.; Salazar-Gonzalez, Raul A.; Walls, Kennedy M.; Hein, David W.
err分享
err收藏
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances
errARCHIVES OF TOXICOLOGY
IF6.9
err2022-09-23
err3
errOAAI
errSalazar-Gonzalez, Raul A.; Doll, Mark A.; Hein, David W.
err分享
err收藏
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes
errARCHIVES OF TOXICOLOGY
IF6.9
err2022-09-16
err2
errOAAI
errHabil, Mariam R.; Salazar-Gonzalez, Raul A.; Doll, Mark A.; Hein, David W.
err分享
err收藏

研究方向

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