Ian R. Humphreys - Publications, H-index & Citations

Ian R. Humphreys

Cardiff University

38H指数

139论文数

4.4K被引数

收录论文 62

发表时间

Cytomegalovirus-induced T cell responses accelerate Alzheimer’s disease progression in mice 巨细胞病毒诱导的T细胞反应加速小鼠阿尔茨海默病进展

Brain

IF11.7

2026-07-13

OAAI

Morgan Marsden; James E McLaren; Ryan J Bevan; Daisy Penn-Ripley; Michelle Somerville; Sarah N Lauder; Manon H Jones; Lila-Blythe Maros; Matthew R McGurk; Awen Gallimore; David A Price; Kelly L Miners; Kristin Ladell; Florian A Siebzehnrubl; Timothy R Hughes; Ian R Humphreys; Mathew Clement; null

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function 线粒体ABHD11抑制驱动甾醇代谢以调节T细胞效应功能

Nature Communications

IF15.7

2025-11-03

OAAI

Benjamin J. Jenkins; Yasmin R. Jenkins; Fernando M. Ponce-Garcia; Chloe Moscrop; Iain A. Perry; Matthew D. Hitchings; Alejandro H. Uribe; Federico Bernuzzi; Simon Eastham; James G. Cronin; Ardena Berisha; Alexandra Howell; Joanne Davies; Julianna Blagih; Marta Williams; Morgan Marsden; Douglas J. Veale; Luke C. Davies; Micah Niphakis; David K. Finlay; Linda V. Sinclair; Benjamin F. Cravatt; Andrew E. Hogan; James A. Nathan; Ian R. Humphreys; Ursula Fearon; David Sumpton; Johan Vande Voorde; Goncalo Dias do Vale; Jeffrey G. McDonald; Gareth W. Jones; James A. Pearson; Emma E. Vincent; Nicholas Jones

Cytomegalovirus-induced peroxynitrite promotes virus entry and contributes to pathogenesis in a murine model of infection

MBIO

IF4.7

2024-08-14

OAAI

Amratia, Pragati S.; Kerr-Jones, Lauren E.; Chapman, Lucy; Marsden, Morgan; Clement, Mathew; Stanton, Richard J.; Humphreys, Ian R.

A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation

CELL REPORTS

IF6.9

2024-06-01

OAAI

Hulin-Curtis, Sarah; Geary, James K.; Maclachlan, Bruce J.; Altmann, Danny M.; Baillon, Laury; Cole, David K.; Greenshields-Watson, Alex; Hesketh, Sophie J.; Humphreys, Ian R.; Jones, Ian M.; Lauder, Sarah N.; Mason, Georgina H.; Smart, Kathryn; Scourfield, D. Oliver; Scott, Jake; Sukhova, Ksenia; Stanton, Richard J.; Wall, Aaron; Rizkallah, Pierre J.; Barclay, Wendy S.; Gallimore, Awen; Godkin, Andrew

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion

SCIENCE IMMUNOLOGY

IF16.3

2023-12-15

OAAI

Whiteside, Sarah K.; Grant, Francis M.; Alvisi, Giorgia; Clarke, James; Tang, Leqi; Imianowski, Charlotte J.; Zhang, Baojie; Evans, Alexander C.; Wesolowski, Alexander J.; Conti, Alberto G.; Yang, Jie; Lauder, Sarah N.; Clement, Mathew; Humphreys, Ian R.; Dooley, James; Burton, Oliver; Liston, Adrian; Alloisio, Marco; Voulaz, Emanuele; Langhorne, Jean; Okkenhaug, Klaus; Lugli, Enrico; Roychoudhuri, Rahul

Best practice for wildlife gut microbiome research: A comprehensive review of methodology for 16S rRNA gene investigations

FRONTIERS IN MICROBIOLOGY

IF4.5

2023-02-22

OAAI

Combrink, Leigh; Humphreys, Ian R.; Washburn, Quinn; Arnold, Holly K.; Stagaman, Keaton; Kasschau, Kristin D.; Jolles, Anna E.; Beechler, Brianna R.; Sharpton, Thomas J.

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses

NATURE COMMUNICATIONS

IF15.7

2022-09-08

OAAI

Clement, M.; Forbester, J. L.; Marsden, M.; Sabberwal, P.; Sommerville, M. S.; Wellington, D.; Dimonte, S.; Clare, S.; Harcourt, K.; Yin, Z.; Nobre, L.; Antrobus, R.; Jin, B.; Chen, M.; Makvandi-Nejad, S.; Lindborg, J. A.; Strittmatter, S. M.; Weekes, M. P.; Stanton, R. J.; Dong, T.; Humphreys, I. R.

The Marine-Derived Macrolactone Mandelalide A Is an Indirect Activator of AMPK

MARINE DRUGS

IF5.4

2022-06-27

OAAI

Mattos, Daphne R.; Wan, Xuemei; Serrill, Jeffrey D.; Nguyen, Minh H.; Humphreys, Ian R.; Viollet, Benoit; Smith, Amos B., III; McPhail, Kerry L.; Ishmael, Jane E.

SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies SARS-CoV-2宿主关闭影响先天NK细胞功能，但抗体依赖性NK活性通过非刺突抗体强烈激活

ELIFE

IF0

2022-05-19

OAAI

Fielding, Ceri Alan; Sabberwal, Pragati; Williamson, James C.; Greenwood, Edward J. D.; Crozier, Thomas W. M.; Zelek, Wioleta; Seow, Jeffrey; Graham, Carl; Huettner, Isabella; Edgeworth, Jonathan D.; Price, David A.; Morgan, Paul B.; Ladell, Kristin; Eberl, Matthias; Humphreys, Ian R.; Merrick, Blair; Doores, Katie; Wilson, Sam J.; Lehner, Paul J.; Wang, Eddie C. Y.; Stanton, Richard J.

An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants

TRANSPLANTATION

IF5

2022-03-08

OAAI

Asderakis, Argiris; Khalid, Usman; Koimtzis, Georgios; Ponsford, Mark J.; Szabo, Laszlo; Chalklin, Christopher; Bramhall, Kathryn; Grant, Leanne; Moat, Stuart J.; Humphreys, Ian R.; Jolles, Stephen R.

Mechanically Ventilated Patients Shed High-Titer Live Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) for Extended Periods From Both the Upper and Lower Respiratory Tract

CLINICAL INFECTIOUS DISEASES

IF7.3

2022-03-01

OAAI

Saud, Zack; Ponsford, Mark; Bentley, Kirsten; Cole, Jade M.; Pandey, Manish; Jolles, Stephen; Fegan, Chris; Humphreys, Ian; Wise, Matt P.; Stanton, Richard

A Systematic Review and Meta-Analysis of Inpatient Mortality Associated With Nosocomial and Community COVID-19 Exposes the Vulnerability of Immunosuppressed Adults

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-10-06

OAAI

Ponsford, Mark J.; Ward, Tom J. C.; Stoneham, Simon M.; Dallimore, Clare M.; Sham, Davina; Osman, Khalid; Barry, Simon M.; Jolles, Stephen; Humphreys, Ian R.; Farewell, Daniel

Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults

THORAX

IF7.7

2021-07-22

OAAI

Ponsford, Mark J.; Jefferies, Rhys; Davies, Chris; Farewell, Daniel; Humphreys, Ian R.; Jolles, Stephen; Fairbairn, Sara; Lewis, Keir; Menzies, Daniel; Benjamin, Amit; Thaivalappil, Favas; Williams, Chris; Barry, Simon M.

Reply to A scientific basis for anxiety about the emergence of resistant strains of Covid-19

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

IF6.4

2021-05-22

OAAI

Humphreys, I. R.; Godkin, A. J.

The potential risks of delaying the second vaccine dose during the SARS-CoV-2 pandemic

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

IF6.4

2021-03-02

OAAI

Humphreys, I. R.; Godkin, A. J.

Genetic influences on viral-induced cytokine responses in the lung

MUCOSAL IMMUNOLOGY

IF7.6

2021-01-01

OAAI

Forbester, Jessica L.; Humphreys, Ian R.

Prevalence of AT1R antibody (AT1R-Ab) among Malaysian multi-ethnic population

HUMAN IMMUNOLOGY

IF2.2

2020-12-01

PREAI

Jalalonmuhali, Maisarah; Caroll, Rob; Deayton, Sue; Emery, Tim; Humphreys, Ian; Lim, Soo Jin; Lim, Soo Kun; Coates, Toby

Impaired Interleukin-27-Mediated Control ofCD4+T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjogren's Syndrome Cd4 T细胞功能的Interleukin-27-Mediated控制受损对干燥综合征患者异位淋巴结构形成的影响

ARTHRITIS & RHEUMATOLOGY

IF10.9

2020-07-21

OAAI

Lucchesi, Davide; Coleby, Rachel; Pontarini, Elena; Prediletto, Edoardo; Rivellese, Felice; Hill, David G.; Soria, Alicia Derrac; Jones, Simon A.; Humphreys, Ian R.; Sutcliffe, Nurhan; Tappuni, Anwar R.; Pitzalis, Costantino; Jones, Gareth W.; Bombardieri, Michele

Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2 Infection 针对病毒脂质包膜的口服冲洗液在SARS-CoV-2感染中的潜在作用

FUNCTION

IF3.8

2020-06-05

100

OAAI

O'Donnell, Valerie B.; Thomas, David; Stanton, Richard; Maillard, Jean-Yves; Murphy, Robert C.; Jones, Simon A.; Humphreys, Ian; Wakelam, Michael J. O.; Fegan, Christopher; Wise, Matt P.; Bosch, Albert; Sattar, Syed A.

A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute ExperimentalTrypanosoma bruceiInfection

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-06-04

OAAI

De Trez, Carl; Stijlemans, Benoit; Bockstal, Viki; Cnops, Jennifer; Korf, Hannelie; Van Snick, Jacques; Caljon, Guy; Muraille, Eric; Humphreys, Ian R.; Boon, Louis; Van Ginderachter, Jo; Magez, Stefan

研究方向