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L

Louise McLeod

hudson institute of medical research
H指数:20
被引数:2,219

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工作经历

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荣誉奖项

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Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer

Chey, Y.C.J.; Kashgari, B.; McLeod, L.; Radford, G.A.; Gearing, L.J.; Dawson, R.E.; Kharbanda, M.; Lundy, J.; Croagh, D.; Girard-Guyonvarc’h, C.; 等. 肿瘤细胞固有的炎症小体蛋白ASC将固有免疫与线粒体代谢联系起来，驱动胰腺癌。Nat. Commun. 2026, 17, 2477. [Google Scholar] [CrossRef] [PubMed]

Nature Communications
IF15.7
2026-02-071
PRE
Chey, Yu C. J.; Kashgari, Bassam; Mcleod, Louise; Radford, Georgette A.; Gearing, Linden J.; Dawson, Ruby E.; Kharbanda, Malvika; Lundy, Joanne; Croagh, Daniel; Girard-Guyonvarc'h, Charlotte; Gabay, Cem; Pereira, Brooke A.; Herrmann, David; Timpson, Paul; Finnie, John W.; Saad, Mohamed I.; Bhuva, Dharmesh D.; Franklin, Bernardo S.; Schmidt, Florian I.; Jenkins, Brendan J.
Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements
JOURNAL OF IMMUNOLOGY
IF3.4
2023-06-052
OAAI
Millrine, David; Figueras, Ana Cardus; Fernandez, Javier Uceda; Andrews, Robert; Szomolay, Barbara; Cossins, Benjamin C.; Rice, Christopher M.; Li, Jasmine; Tyrrell, Victoria J.; McLeod, Louise; Holmans, Peter; O'Donnell, Valerie B.; Taylor, Philip R.; Turner, Stephen J.; Jenkins, Brendan J.; Jones, Gareth W.; Topley, Nicholas; Williams, Nigel M.; Jones, Simon A.
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema

IL-6反式信号与AIM2炎性体/IL-1β 轴之间的串扰桥接先天免疫和上皮细胞凋亡促进肺气肿

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-08-2910
OAAI
Ruwanpura, Saleela M.; McLeod, Louise; Dousha, Lovisa F.; Seow, Huei J.; West, Alison C.; West, Alice J.; Weng, Teresa; Alanazi, Mohammad; MacDonald, Martin; King, Paul T.; Bardin, Philip G.; Gabay, Cem; Klinman, Dennis M.; Bozinovski, Steven; Vlahos, Ross; Anderson, Gary P.; Rose-John, Stefan; Saad, Mohamed I.; Jenkins, Brendan J.
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
EMBO MOLECULAR MEDICINE
IF8.3
2019-03-0466
OAAI
Saad, Mohamed I.; Alhayyani, Sultan; McLeod, Louise; Yu, Liang; Alanazi, Mohammad; Deswaerte, Virginie; Tang, Ke; Jarde, Thierry; Smith, Julian A.; Prodanovic, Zdenka; Tate, Michelle D.; Balic, Jesse J.; Watkins, D. Neil; Cain, Jason E.; Bozinovski, Steven; Algar, Elizabeth; Kohmoto, Tomohiro; Ebi, Hiromichi; Ferlin, Walter; Garbers, Christoph; Ruwanpura, Saleela; Sagi, Irit; Rose-John, Stefan; Jenkins, Brendan J.
Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development

过度活跃的gp130/STAT3-driven胃肿瘤发生促进粘膜下三级淋巴结构发育

INTERNATIONAL JOURNAL OF CANCER
IF4.7
2018-02-1950
OAAI
Hill, David G.; Yu, Liang; Gao, Hugh; Balic, Jesse J.; West, Alison; Oshima, Hiroko; McLeod, Louise; Oshima, Masanobu; Gallimore, Awen; D'Costa, Kimberley; Bhathal, Prithi S.; Sievert, William; Ferrero, Richard L.; Jenkins, Brendan J.; Jones, Gareth W.
Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2016-12-1538
OAAI
Ruwanpura, Saleela M.; McLeod, Louise; Dousha, Lovisa F.; Seow, Huei J.; Alhayyani, Sultan; Tate, Michelle D.; Deswaerte, Virginie; Brooks, Gavin D.; Bozinovski, Steven; MacDonald, Martin; Garbers, Christoph; King, Paul T.; Bardin, Philip G.; Vlahos, Ross; Rose-John, Stefan; Anderson, Gary P.; Jenkins, Brendan J.
Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

Interleukin-6信号在未解决的炎症中驱动纤维化

IMMUNITY
IF26.3
2014-01-01304
OAAI
Fielding, Ceri A.; Jones, Gareth W.; McLoughlin, Rachel M.; McLeod, Louise; Hammond, Victoria J.; Uceda, Javier; Williams, Anwen S.; Lambie, Mark; Foster, Thomas L.; Liao, Chia-Te; Rice, Christopher M.; Greenhill, Claire J.; Colmont, Chantal S.; Hams, Emily; Coles, Barbara; Kift-Morgan, Ann; Newton, Zarabeth; Craig, Katherine J.; Williams, John D.; Williams, Geraint T.; Davies, Simon J.; Humphreys, Ian R.; O'Donnell, Valerie B.; Taylor, Philip R.; Jenkins, Brendan J.; Topley, Nicholas; Jones, Simon A.

研究方向

暂未获取到该数据
B
Brendan J. Jenkins
H 指数:50论文数:229被引数:1.1万
S
Saleela M. Ruwanpura
H 指数:19论文数:53被引数:1,757
S
Simon A. Jones
H 指数:71论文数:267被引数:2.2万
S
Steven Bozinovski
H 指数:51论文数:201被引数:7,512
G
Gary P. Anderson
H 指数:56论文数:334被引数:1.2万
G
Gareth W. Jones
H 指数:37论文数:131被引数:5,118
C
Catherine L. Kennedy
H 指数:15论文数:27被引数:1,449
A
Alistair Miller
H 指数:16论文数:70被引数:734
S
Stefan Rose‐John
H 指数:129论文数:911被引数:6.7万
M
Meri Najdovska
H 指数:14论文数:43被引数:2,011