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Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens RBD纳米颗粒和融合前稳定的刺突免疫原对SARS-CoV-2变体的有效中和 Miranda, Marcos C.; Kepl, Elizabeth; Navarro, Mary Jane; Chen, Chengbo; Johnson, Max; Sprouse, Kaitlin R.; Stewart, Cameron; Palser, Anne; Valdez, Adian; Pettie, Deleah; Sydeman, Claire; Ogohara, Cassandra; Kraft, John C.; Pham, Minh; Murphy, Michael; Wrenn, Sam; Fiala, Brooke; Ravichandran, Rashmi; Ellis, Daniel; Carter, Lauren; Corti, Davide; Kellam, Paul; Lee, Kelly; Walls, Alexandra C.; Veesler, David; King, Neil P. 分享 收藏
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8 Roy, Anindya; Shi, Lei; Chang, Ashley; Dong, Xianchi; Fernandez, Andres; Kraft, John C.; Li, Jing; Le, Viet Q.; Winegar, Rebecca Viazzo; Cherf, Gerald Maxwell; Slocum, Dean; Poulson, P. Daniel; Casper, Garrett E.; Vallecillo-Zuniga, Mary L.; Valdoz, Jonard Corpuz; Miranda, Marcos C.; Bai, Hua; Kipnis, Yakov; Olshefsky, Audrey; Priya, Tanu; Carter, Lauren; Ravichandran, Rashmi; Chow, Cameron M.; Johnson, Max R.; Cheng, Suna; Smith, McKaela; Overed-Sayer, Catherine; Finch, Donna K.; Lowe, David; Bera, Asim K.; Matute-Bello, Gustavo; Birkland, Timothy P.; DiMaio, Frank; Raghu, Ganesh; Cochran, Jennifer R.; Stewart, Lance J.; Campbell, Melody G.; Van Ry, Pam M.; Springer, Timothy; Baker, David 分享 收藏
Computational design of constitutively active cGAS Dowling, Quinton M.; Volkman, Hannah E.; Gray, Elizabeth E.; Ovchinnikov, Sergey; Cambier, Stephanie; Bera, Asim K.; Sankaran, Banumathi; Johnson, Max R.; Bick, Matthew J.; Kang, Alex; Stetson, Daniel B.; King, Neil P. 分享 收藏
Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens 对蛋白质纳米颗粒免疫原的抗原和支架特异性抗体反应 Kraft, John C.; Pham, Minh N.; Shehata, Laila; Brinkkemper, Mitch; Boyoglu-Barnum, Seyhan; Sprouse, Kaitlin R.; Walls, Alexandra C.; Cheng, Suna; Murphy, Mike; Pettie, Deleah; Ahlrichs, Maggie; Sydeman, Claire; Johnson, Max; Blackstone, Alyssa; Ellis, Daniel; Ravichandran, Rashmi; Fiala, Brooke; Wrenn, Samuel; Miranda, Marcos; Sliepen, Kwinten; Brouwer, Philip J. M.; Antanasijevic, Aleksandar; Veesler, David; Ward, Andrew B.; Kanekiyo, Masaru; Pepper, Marion; Sanders, Rogier W.; King, Neil P. 分享 收藏
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses McLeod, Brandon; Mabrouk, Moustafa T.; Miura, Kazutoyo; Ravichandran, Rashmi; Kephart, Sally; Hailemariam, Sophia; Pham, Thao P.; Semesi, Anthony; Kucharska, Iga; Kundu, Prasun; Huang, Wei-Chiao; Johnson, Max; Blackstone, Alyssa; Pettie, Deleah; Murphy, Michael; Kraft, John C.; Leaf, Elizabeth M.; Jiao, Yang; Van de Vegte-Bolmer, Marga; Van Gemert, Geert-Jan; Ramjith, Jordache; King, C. Richter; MacGill, Randall S.; Wu, Yimin; Lee, Kelly K.; Jore, Matthijs M.; King, Neil P.; Lovell, Jonathan F.; Julien, Jean-Philippe 分享 收藏
Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice 接种疫苗的人和小鼠对SARS-CoV-2变异的不同敏感性 Walls, Alexandra C.; VanBlargan, Laura A.; Wu, Kai; Choi, Angela; Navarro, Mary Jane; Lee, Diana; Avena, Laura; Berrueta, Daniela Montes; Pham, Minh N.; Elbashir, Sayda; Kraft, John C.; Miranda, Marcos C.; Kepl, Elizabeth; Johnson, Max; Blackstone, Alyssa; Sprouse, Kaitlin; Fiala, Brooke; O'Connor, Megan A.; Brunette, Natalie; Arunachalam, Prabhu S.; Shirreff, Lisa; Rogers, Kenneth; Carter, Lauren; Fuller, Deborah H.; Villinger, Francois; Pulendran, Bali; Diamond, Michael S.; Edwards, Darin K.; King, Neil P.; Veesler, David 分享 收藏
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice Hunt, Andrew C.; Case, James Brett; Park, Young-Jun; Cao, Longxing; Wu, Kejia; Walls, Alexandra C.; Liu, Zhuoming; Bowen, John E.; Yeh, Hsien-Wei; Saini, Shally; Helms, Louisa; Zhao, Yan Ting; Hsiang, Tien-Ying; Starr, Tyler N.; Goreshnik, Inna; Kozodoy, Lisa; Carter, Lauren; Ravichandran, Rashmi; Green, Lydia B.; Matochko, Wadim L.; Thomson, Christy A.; Vogeli, Bastian; Kruger, Antje; VanBlargan, Laura A.; Chen, Rita E.; Ying, Baoling; Bailey, Adam L.; Kafai, Natasha M.; Boyken, Scott E.; Ljubetic, Ajasja; Edman, Natasha; Ueda, George; Chow, Cameron M.; Johnson, Max; Addetia, Amin; Navarro, Mary-Jane; Panpradist, Nuttada; Gale, Michael, Jr.; Freedman, Benjamin S.; Bloom, Jesse D.; Ruohola-Baker, Hannele; Whelan, Sean P. J.; Stewart, Lance; Diamond, Michael S.; Veesler, David; Jewett, Michael C.; Baker, David 分享 收藏
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Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design Ellis, Daniel; Brunette, Natalie; Crawford, Katharine H. D.; Walls, Alexandra C.; Pham, Minh N.; Chen, Chengbo; Herpoldt, Karla-Luise; Fiala, Brooke; Murphy, Michael; Pettie, Deleah; Kraft, John C.; Malone, Keara D.; Navarro, Mary Jane; Ogohara, Cassandra; Kepl, Elizabeth; Ravichandran, Rashmi; Sydeman, Claire; Ahlrichs, Maggie; Johnson, Max; Blackstone, Alyssa; Carter, Lauren; Starr, Tyler N.; Greaney, Allison J.; Lee, Kelly K.; Veesler, David; Bloom, Jesse D.; King, Neil P. 分享 收藏
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