Kimberly N. Kremer

University of Colorado System

H指数:15

被引数:923

个人简介

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Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-01-170

OAAI

Regulation of CD8 T-cell signaling, metabolism, and cytotoxic activity by extracellular lysophosphatidic acid

细胞外溶血磷脂酸对CD8 T细胞信号传导，代谢和细胞毒活性的调节

IMMUNOLOGICAL REVIEWS

IF8.3

2023-04-254

PRE

LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation

LPA通过改变细胞骨架和破坏免疫突触形成来抑制T细胞功能

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-04-0817

OAAI

LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling

LPA5是一种抑制性受体，可通过破坏早期TCR信号传导来抑制CD8 T细胞的细胞毒性功能

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-05-2862

OAAI

ARHGEF1 deficiency reveals Gα13-associated GPCRs are critical regulators of human lymphocyte function

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-02-045

GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3K/PREX1 signaling and T cell cytokine secretion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-09-0125

OAAI

Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis

JOURNAL OF IMMUNOLOGY

IF3.4

2018-08-0111

OAAI

Osteoblast-lineage cells protect AML cells from cytarabine-induced apoptosis via a mechanism sensitive to HDACi and reduced cell-cell contact

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Osteoblasts protect AML cells from cytarabine-induced death

CANCER RESEARCH

IF16.6

2017-07-010

PRE

Manipulating osteoblast differentiation in order to inhibit protection of AML cells within the bone marrow

操纵成骨细胞分化以抑制骨髓内AML细胞的保护

CANCER RESEARCH

IF16.6

2016-07-150

PRE

Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts

组蛋白去乙酰化酶抑制剂通过增强成骨细胞Nherf1-Protein磷酸酶1α-TAZ信号通路靶向白血病微环境

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-12-0121

OAAI

IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes

JOURNAL OF CELL BIOLOGY

IF6.4

2015-07-2018

OAAI

Osteoblasts Protect AML Cells From SDF-1-Induced Apoptosis

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2014-04-1538

β-Arrestin1 and Distinct CXCR4 Structures Are Required for Stromal Derived Factor-1 to Downregulate CXCR4 Cell-Surface Levels in Neuroblastoma

MOLECULAR PHARMACOLOGY

IF3

2014-04-0126

OAAI

CXCR4 Chemokine Receptor Signaling Induces Apoptosis in Acute Myeloid Leukemia Cells via Regulation of the Bcl-2 Family Members Bcl-XL, Noxa, and Bak

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-08-0162

OAAI

Gαi2 and ZAP-70 Mediate RasGRP1 Membrane Localization and Activation of SDF-1-Induced T Cell Functions

JOURNAL OF IMMUNOLOGY

IF3.4

2011-09-1520

OAAI

Stromal Cell-Derived Factor-1 Signaling via the CXCR4-TCR Heterodimer Requires Phospholipase C-β3 and Phospholipase C-γ1 for Distinct Cellular Responses

JOURNAL OF IMMUNOLOGY

IF3.4

2011-08-0145

OAAI

Gα13 and Rho Mediate Endosomal Trafficking of CXCR4 into Rab11+ Vesicles upon Stromal Cell-Derived Factor-1 Stimulation

JOURNAL OF IMMUNOLOGY

IF3.4

2011-01-1553

OAAI

Haplotype-independent costimulation of IL-10 secretion by SDF-1/CXCL12 proceeds via AP-1 binding to the human IL-10 promoter

JOURNAL OF IMMUNOLOGY

IF3.4

2007-02-0141

OAAI

CXCR4 physically associates with the T cell receptor to signal in T cells

IMMUNITY

IF26.3

2006-08-01220

Kimberly N. Kremer

个人简介

教育背景

工作经历

荣誉奖项

研究方向