Pollyana Ribeiro Castro; Renan Oliveira Corrêa; Monara Kaélle Sérvulo Cruz Angelim; Vinícius de Rezende Rodovalho; Mariane Font Fernandes; Vinícius Dias Nirello; Arilson Bernardo dos Santos Pereira Gomes; Jaqueline de Souza Felipe; Lais Passarielo Pral; Sarah de Oliveira; Patrícia Brito Rodrigues; José Luís Fachi; Guilherme Reis-de-Oliveira; Bradley J. Smith; Victor C. Carregari; Nicolas G. Shealy; Catherine Shelton; Daniel Martins-de-Souza; Pedro M. Moraes–Vieira; Mariana Xavier Byndloss; Patrick Varga-Weisz; Marco Aurélio Ramirez Vinolo

Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt

circadian circuits通过维持RORγt的表观遗传配置来控制group 3 innate lymphoid cells的塑性

Nature Immunology

IF27.6

2025-08-130

PRE

Article Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

文章标题：纤维和醋酸介导的肠上皮MHC-II表达调节可保护免受Clostridioides difficile感染

CELL HOST & MICROBE

IF18.7

2025-02-011

OAAI

NKp46+ILC3s promote early neutrophil defense against Clostridioides difficile infection through GM-CSF secretion

NKp46 ILC3s通过gm-csf分泌促进中性粒细胞早期防御艰难梭菌感染

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-301

OAAI

Editorial: Molecular insights of microbiota and innate lymphoid cell interactions

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-10-110

OAAI

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy

TREM2缺陷重新编程肠巨噬细胞和微生物群以增强anti-PD-1肿瘤免疫治疗

SCIENCE IMMUNOLOGY

IF16.3

2024-05-173

The IRE1 α /XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-05-091

OAAI

Deficiency of IL-22-binding protein enhances the ability of the gut microbiota to protect against enteric pathogens

IL-22-binding蛋白缺乏增强肠道菌群抵御肠道病原体的能力

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-300

OAAI

Reviewing the Clostridioides difficile Mouse Model: Insights into Infection Mechanisms

MICROORGANISMS

IF4.2

2024-01-275

OAAI

Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

GUT MICROBES

IF11

2024-01-024

OAAI

A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells

一种表达MHCII和ror γ t的独特人类细胞类型，具有树突状细胞和3型固有淋巴样细胞的双重特征

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-12-189

OAAI

Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium

MICROBIOME

IF12.7

2023-04-2616

OAAI

Correa, Renan Oliveira; Castro, Pollyana Ribeiro; Fachi, Jose Luis; Nirello, Vinicius Dias; El-Sahhar, Salma; Imada, Shinya; Pereira, Gabriel Vasconcelos; Pral, Lais Passariello; Pereira Araujo, Nathalia Vitoria; Fernandes, Mariane Font; Matheus, Valquiria Aparecida; de Souza Felipe, Jaqueline; dos Santos Pereira Gomes, Arilson Bernardo; de Oliveira, Sarah; de Rezende Rodovalho, Vinicius; Machado de Oliveira, Samantha Roberta; de Assis, Helder Carvalho; Oliveira, Sergio Costa; Dos Santos Martins, Flaviano; Martens, Eric; Colonna, Marco; Varga-Weisz, Patrick; Ramirez Vinolo, Marco Aurelio

Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

IMMUNITY

IF26.3

2023-04-0160

PRE

Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

EBIOMEDICINE

IF10.8

2022-03-0146

OAAI

Antunes, Krist H.; Stein, Renato T.; Franceschina, Caroline; da Silva, Emanuelle F.; de Freitas, Deise N.; Silveira, Josiane; Mocellin, Magali; Leitao, Lidiane; Fachi, Jose L.; Pral, Lais P.; Gonzalez, Amanda; Oliveira, Sarah; Duarte, Leonardo; Cassao, Gisele; Goncalves, Joao I. B.; Reis, Tatiane M.; Abbadi, Bruno L.; Dornelles, Maiele; Sperotto, Nathalia D. M.; Rigo, Mauricio; Rodrigues, Hosana; Jones, Marcus; Epifanio, Matias; Guima, Suzana; Setubal, Joao C.; Jorge, Taissa R.; Mansur, Daniel S.; Mayer, Fabiana Q.; Varela, Ana Paula M.; Bizarro, Cristiano, V; Machado, Pablo; Basso, Luiz A.; Polack, Fernando P.; Custovic, Adnan; Vinolo, Marco A. R.; de Souza, Ana Paula D.

José Luís Fachi

个人简介

教育背景

工作经历

荣誉奖项

研究方向