Revealing 5-(3,5-difluorobenzyl)-1H-indazole as the active pharmacophore of ALK/ROS1 dual inhibitors through theoretical calculations and biological activity evaluations通过理论计算和生物活性评价,揭示5-(3,5-二氟苄基)-1H-吲唑作为ALK/ROS1双抑制剂的活性药效基团。BIOORGANIC CHEMISTRYIF4.72025-01-010PRE