未登录 Lessons learned from 20 years of preclinical testing in pediatric cancers 从20年的儿科癌症临床前测试中吸取的经验教训 Smith, Malcolm A.; Houghton, Peter J.; Lock, Richard B.; Maris, John M.; Gorlick, Richard; Kurmasheva, Raushan T.; Li, Xiao-Nan; Teicher, Beverly A.; Chuang, Jeffrey H.; Cruz, Filemon S. Dela; Dyer, Michael A.; Kung, Andrew L.; Lloyd, Michael W.; Mosse, Yael P.; Stearns, Timothy M.; Stewart, Elizabeth A.; Bult, Carol J.; Erickson, Stephen W. 分享 收藏
BMP signaling determines neuroblastoma sensitivity to retinoic acid by directing cell fate Pan, Min; Zhang, Yinwen; Wright, William C.; Lee, Hyeong-Min; Chapple, Richard H.; Liu, Xueying; Low, Jonathan; Currier, Duane; Loughran, Allister J.; Dyer, Michael A.; Pruett, Shondra M.; Freeman, Burgess, III; Chen, Taosheng; Abraham, Brian J.; Stewart, Elizabeth; Easton, John; Geeleher, Paul 分享 收藏
An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs Chapple, Richard H.; Liu, Xueying; Natarajan, Sivaraman; Alexander, Margaret I. M.; Kim, Yuna; Patel, Anand G.; LaFlamme, Christy W.; Pan, Min; Wright, William C.; Lee, Hyeong-Min; Zhang, Yinwen; Lu, Meifen; Koo, Selene C.; Long, Courtney; Harper, John; Savage, Chandra; Johnson, Melissa D.; Confer, Thomas; Akers, Walter J.; Dyer, Michael A.; Sheppard, Heather; Easton, John; Geeleher, Paul 分享 收藏
An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs Chapple, Richard H.; Liu, Xueying; Natarajan, Sivaraman; Alexander, Margaret I. M.; Kim, Yuna; Patel, Anand G.; LaFlamme, Christy W.; Pan, Min; Wright, William C.; Lee, Hyeong-Min; Zhang, Yinwen; Lu, Meifen; Koo, Selene C.; Long, Courtney; Harper, John; Savage, Chandra; Johnson, Melissa D.; Confer, Thomas; Akers, Walter J.; Dyer, Michael A.; Sheppard, Heather; Easton, John; Geeleher, Paul 分享 收藏
A novel unsupervised machine learning model applied to neuroblastoma single-cell RNA-seq data reveals a drug-induced mesenchymal-like gene expression program Chapple, Rich; Liu, Xueying; Natarajan, Sivaraman; Alexander, Margaret I.; Kim, Yuna; Patel, Anand; LaFlamme, Christy W.; Pan, Min; Wright, William C.; Lee, Hyeong-Min; Zhang, Yinwen; Lu, Meifen; Koo, Selene C.; Long, Courtney; Harper, John; Savage, Chandra; Johnson, Melissa D.; Confer, Thomas; Akers, Walter J.; Dyer, Michael A.; Sheppard, Heather; Easton, John; Geeleher, Paul 分享 收藏
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Ontology guided navigation of somatic variants, mutational signatures, gene expression and histology images for pediatric cancer Gout, Alexander M.; Sandor, Stephanie; Rahbarinia, Delaram; Sunny, Jobin; Madson, James; Vacaroiu, Lucian; Yang, Wentao; Lansdell, Ben; Macias, Michael; Brady, Samuel W.; Finkelstein, David; Pastor, Victor; Benton, Kevin; Frantz, Andrew; Wilkinson, Mark R.; Cline, Cynthia; Orr, Brent A.; Shirinifard, Abbas; Stewart, Elizabeth; Rusch, Michael; Zhou, Xin; Dyer, Michael; Wheeler, David A.; McLeod, Clay; Zhang, Jinghui 分享 收藏
Changes in Retinoblastoma Cell Adhesion Associated with Optic Nerve Invasion Laurie, Nikia; Mohan, Adithi; McEvoy, Justina; Reed, Damon; Zhang, Jiakun; Schweers, Brett; Ajioka, Itsuki; Valentine, Virginia; Johnson, Dianna; Ellison, David; Dyer, Michael A. 分享 收藏
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Methylation profiling reveals novel molecular classes of rhabdomyosarcoma Clay, Michael R.; Patel, Anand; Tran, Quynh; Hedges, Dale J.; Chang, Ti-Cheng; Stewart, Elizabeth; Charville, Greg; Cline, Cynthia; Dyer, Michael A.; Orr, Brent A. 分享 收藏
Antigen-cross presentation promotes development of terminally differentiated CD8 T cells in young individuals Moustaki, Ardiana; Crawford, Jeremy Chase; Alli, Shanta; Zamora, Anthony; Fan, Yiping; Boi, Shannon; McDonald, Natalie M.; Thomas, Paul G.; Pappo, Alberto S.; Dyer, Michael A.; Stewart, Elizabeth; Federico, Sara; Youngblood, Ben 分享 收藏
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Nucleome Dynamics during Retinal Development 视网膜发育过程中的核组动力学 Norrie, Jackie L.; Lupo, Marybeth S.; Xu, Beisi; Al Diri, Issam; Valentine, Marc; Putnam, Daniel; Griffiths, Lyra; Zhang, Jiakun; Johnson, Dianna; Easton, John; Shao, Ying; Honnell, Victoria; Frase, Sharon; Miller, Shondra; Stewart, Valerie; Zhou, Xin; Chen, Xiang; Dyer, Michael A. 分享 收藏
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors 小分子和CRISPR筛选融合揭示小儿横纹肌样瘤中受体酪氨酸激酶的依赖性 Oberlick, Elaine M.; Rees, Matthew G.; Seashore-Ludlow, Brinton; Vazquez, Francisca; Nelson, Geoffrey M.; Dharia, Neekesh V.; Weir, Barbara A.; Tsherniak, Aviad; Ghandi, Mahmoud; Krill-Burger, John M.; Meyers, Robin M.; Wang, Xiaofeng; Montgomery, Phil; Root, David E.; Bieber, Jake M.; Radko, Sandi; Cheah, Jaime H.; Hon, C. Suk-Yee; Shamji, Alykhan F.; Clemons, Paul A.; Park, Peter J.; Dyer, Michael A.; Golub, Todd R.; Stegmaier, Kimberly; Hahn, William C.; Stewart, Elizabeth A.; Schreiber, Stuart L.; Roberts, Charles W. M. 分享 收藏
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ATRX IN-FRAME FUSION NEUROBLASTOMA IS SENSITIVE TO EZH2 INHIBITION VIA MODULATION OF NEURONAL GENE SIGNATURES Qadeer, Zulekha; Valle-Garcia, David; Hasson, Dan; Soriano, Aroa; Ma, Anqi; Griffiths, Lyra; Zeineldin, Maged; Sun, Zhen; Jubierre, Luz; Filipescu, Dan; Chowdhury, Asif; Deevy, Orla; Chen, Xiang; Finkelstein, David; Bahrami, Armita; Meni, David; Stewart, Elizabeth; Federico, Sara; Gallego, Soledad; Dekio, Fumiko; Fowkes, Mary; Maris, John; Weiss, William; Roberts, Stephen; Cheung, Nai-Kong; Jin, Jian; Segura, Miguel; Dyer, Michael; Bernstein, Emily 分享 收藏
Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma Zeineldin, Maged; Federico, Sara M.; Griffith, Lyra; Jeon, Jongyre; Chen, Xiang; Easton, John; Wu, Jianrong; Mao, Shenghua; Liu, Yanling; Naranjo, Arlene; Pappo, Alberto S.; Hogarty, Michael D.; Dyer, Michael A. 分享 收藏
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