未登录Optimizing the cutoff for the identification of skin sensitizers by the HaCaSens assay: Introducing an ROC-analysis-based cutoff approach
Chung, Hyewon; Kim, Eunju; Quan, Hailian; Jung, Daun; Gautam, Ravi; Cho, Ahrang; Kim, Chang Yul; Kang, MiJeong; Che, Jeong-Hwan; Lee, Eung-Seok; Jeong, Tae Cheon; Heo, Yong; Seok, Seung Hyeok .png)
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收藏Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agentsMagar, Til Bahadur Thapa; Seo, Seung Hee; Kadayat, Tara Man; Jo, Hyunji; Shrestha, Aarajana; Bist, Ganesh; Katila, Pramila; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 分享 收藏 分享 收藏 Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitorPark, Seojeong; Magar, Til Bahadur Thapa; Kadayat, Tara Man; Lee, Hwa Jong; Bist, Ganesh; Shrestha, Aarajana; Lee, Eung-Seok; Kwon, Youngjoo 分享 收藏 A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR studyKarki, Radha; Jun, Kyu-Yeon; Kadayat, Tara Man; Shin, Somin; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 分享 收藏 Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agentsThapa, Pritam; Jun, Kyu-Yeon; Kadayat, Tara Man; Park, Chanmi; Zheng, Zhi; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridinesKadayat, Tara Man; Song, Chanju; Shin, Somin; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Thapa, Pritam; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridinesKarki, Radha; Song, Chanju; Kadayat, Tara Man; Magar, Til Bahadur Thapa; Bist, Ganesh; Shrestha, Aarajana; Na, Younghwa; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 分享 收藏 A Series of Novel Terpyridine-Skeleton Molecule Derivants Inhibit Tumor Growth and Metastasis by Targeting TopoisomerasesKwon, Han-Byeol; Park, Chanmi; Jeon, Kyung-Hwa; Lee, Eunyoung; Park, So-Eun; Jun, Kyu-Yeon; Kadaya, Tara Man; Thapa, Pritam; Karki, Radha; Na, Younghwa; Park, Mi Sun; Rho, Seung Bae; Lee, Eung-Seok; Kwon, Youngjoo 分享 收藏 分享 收藏 Synthesis, antitumor,activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitorsKarki, Radha; Park, Chanmi; Jun, Kyu-Yeon; Jee, Jun-Goo; Lee, Jun-Ho; Thapa, Pritam; Kadayat, Tara Man; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors作为拓扑异构酶抑制剂的细胞毒性3-杂芳基异喹啉胺的设计，合成和系统评价Hue Thi My Van; Woo, Hyunjung; Jeong, Hyung Min; Khadka, Daulat Bikram; Yang, Su Hui; Zhao, Chao; Jin, Yifeng; Lee, Eung-Seok; Lee, Kwang You; Kwon, Youngjoo; Cho, Won-Jea 分享 收藏 Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitorJun, Kyu-Yeon; Kwon, Hanbyeol; Park, So-Eun; Lee, Eunyoung; Karki, Radha; Thapa, Pritam; Lee, Jun-Ho; Lee, Eung-Seok; Kwon, Youngjoo 分享 收藏 Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moietyThapa, Pritam; Karki, Radha; Yun, Minho; Kadayat, Tara Man; Lee, Eunyoung; Kwon, Han Byeol; Na, Younghwa; Cho, Won-Jea; Kim, Nam Doo; Jeong, Byeong-Seon; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship studyKarki, Radha; Thapa, Pritam; Yoo, Han Young; Kadayat, Tara Man; Park, Pil-Hoon; Na, Youngwha; Lee, Eunyoung; Jeon, Kyung-Hwa; Cho, Won-Jea; Choi, Heesung; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationshipThapa, Uttam; Thapa, Pritam; Karki, Radha; Yun, Minho; Choi, Jae Hun; Jahng, Yurngdong; Lee, Eunyoung; Jeon, Kyung-Hwa; Na, Younghwa; Ha, Eun-Mi; Cho, Won-Jea; Kwon, Youngjoo; Lee, Eung-Seok 分享 收藏 分享 收藏 
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