Rubén J. Boado - Publications, H-index & Citations

Rubén J. Boado

University of California

62H指数

294论文数

1.2W被引数

收录论文 70

发表时间

Antibody-Based Biologics for CNS Disorders 抗体为基础的生物制剂用于中枢神经系统疾病

Antibodies

IF2.7

2026-09-17

OAAI

Eric Ka-Wai Hui; Ruben J. Boado

OBITUARY The legacy of William M. Pardridge (1947-2024) on the science and fields concerned with the physiology of the blood-brain barrier and the transport of drugs to the brain 讣告威廉·M·帕德里奇（William M. Pardridge，1947-2024）在血液-脑屏障生理学及相关药物输送至大脑的科学和领域中的遗产

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2025-05-07

OAAI

Boado, Ruben J.; Bickel, Ulrich; Sumbria, Rachita K.

Treatment of CLN1 disease with a blood-brain barrier penetrating lysosomal enzyme AGT-194

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-02-01

PREAI

Hahn, Andreas; Sato, Yuji; Ikeda, Toshiaki; Sonoda, Hiroyuki; Schmidt, Mathias; Pfrimmer, Charlotte; Boado, Ruben; Pardridge, William M.

Bi-functional IgG-lysosomal enzyme fusion proteins for brain drug delivery 用于脑药物递送的双功能IgG-溶酶体酶融合蛋白

SCIENTIFIC REPORTS

IF3.9

2019-12-09

OAAI

Boado, Ruben J.; Lu, Jeff Zhiqiang; Hui, Eric Ka-Wai; Lin, Huilan; Pardridge, William M.

Platform technology for treatment of the brain in lysosomal disorders: Application to Niemann-Pick disease type A

MOLECULAR GENETICS AND METABOLISM

IF3.5

2019-02-01

PREAI

Lu, Jeff Z.; Hui, Eric K. -W.; Lin, Huilan; Boado, Ruben J.; Pardridge, William M.

Platform technology for treatment of the brain in lysosomal diseases: Application to NCL1 Batten disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2019-02-01

PREAI

Pardridge, William M.; Hui, Eric K. -W.; Lu, Jeff Z.; Lin, Huilan; Boado, Ruben J.

Preclinical studies of a brain penetrating IgG Trojan horse-arylsulfatase fusion protein in the metachromatic leukodystrophy mouse

MOLECULAR GENETICS AND METABOLISM

IF3.5

2019-02-01

PREAI

Hui, Eric K. -W.; Lu, Jeff Z.; Boado, Ruben J.; Pardridge, William M.

Platform technology for treatment of the brain in lysosomal disorders: Application to Tay-Sachs disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2019-02-01

PREAI

Boado, Ruben J.; Hui, Eric K. -W.; Lu, Jeff Z.; Lin, Huilan; Pardridge, William M.

Neurocognitive and somatic stabilization in pediatric patients with severe Mucopolysaccharidosis Type I after 52 weeks of intravenous brain-penetrating insulin receptor antibody-iduronidase fusion protein (valanafusp alpha): an open label phase 1-2 trial 静脉注射脑穿透性胰岛素受体抗体-iduronidase融合蛋白 (valanafusp alpha) 52周后，严重I型粘多糖贮积症患儿的神经认知和体细胞稳定: 一项开放标签1-2期试验

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2018-07-05

111

OAAI

Giugliani, Roberto; Giugliani, Luciana; Poswar, Fabiano de Oliveira; Donis, Karina Carvalho; Dalla Corte, Amauri; Schmidt, Mathias; Boado, Ruben J.; Nestrasil, Igor; Nguyen, Carol; Chen, Steven; Pardridge, William M.

Plasma Pharmacokinetics of Valanafusp Alpha, a Human Insulin Receptor Antibody-Iduronidase Fusion Protein, in Patients with Mucopolysaccharidosis Type I I型粘多糖贮积症患者的人胰岛素受体抗体-Iduronidase融合蛋白Valanafusp α 的血浆药代动力学

BIODRUGS

IF6.9

2018-02-13

PREAI

Pardridge, William M.; Boado, Ruben J.; Giugliani, Roberto; Schmidt, Mathias

Anti-drug antibody response in mucopolysaccharidosis type I patients treated with AGT-181, a brain penetrating human insulin receptor antibody-iduronidase fusion protein

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Schmidt, Mathias; Boado, Ruben J.; Giugliani, Roberto; Pardridge, William M.

Somatic effects of AGT-181 in patients with mucopolysaccharidosis I enrolled in a phase I/II clinical trial in Brazil

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Giugliani, Luciana; Donis, Karina Carvalho; Poswar, Fabiano; Giugliani, Roberto; Boado, Ruben

Safety and clinical efficacy of AGT-181, a brain penetrating human insulin receptor antibody-iduronidase fusion protein, in a 26-week study with pediatric patients with mucopolysaccharidosis type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Giugliani, Roberto; Giugliani, Luciana; Corte, Amauri Dalla; Poswar, Fabiano; Donis, Karina; Schmidt, Mathias; Hunt, Douglas; Boado, Ruben J.; Pardridge, William M.

Plasma pharmacokinetics of a human insulin receptor antibody-iduronidase fusion protein in patients with mucopolysaccharidosis type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Pardridge, William M.; Boado, Ruben J.; Giugliani, Roberto; Schmidt, Mathias

Platform technology for treatment of the brain in lysosomal disorders

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Kelaita, Derek; Hui, Eric K. -W.; Lu, Jeff Z.; Lin, Huilan; Boado, Ruben J.; Pardridge, William M.