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DECIPHERING THE LONGITUDINAL TRAJECTORIES OF GLIOBLASTOMA ECOSYSTEMS BY INTEGRATIVE SINGLE-CELL GENOMICS 通过整合单细胞基因组学解析胶质母细胞瘤生态系统的纵向轨迹 Spitzer, A.; Johnson, K.; Nomura, M.; Garofano, L.; Nehar-Belaid, D.; Galili Darnell, N.; Greenwald, A.; Bussema, L.; Oh, Y.; Varn, F. S.; D'Angelo, F.; Gritsch, S.; Anderson, K. J.; Migliozzi, S.; Gonzalez Castro, L.; Chowdhury, T.; Robine, N.; Reeves, C.; Park, J.; Lipsa, A.; Hertel, F.; Golebiewska, A.; Niclou, S.; Nusrat, L.; Kellett, S.; Das, S.; Moon, H.; Paek, S.; Bielle, F.; Laurenge, A.; Di Stefano, A.; Mathon, B.; Picca, A.; Sanson, M.; Tanaka, S.; Saito, N.; Ashley, D. M.; Keir, S. T.; Ligon, K. L.; Huse, J. T.; Yung, W.; Lasorella, A.; Iavarone, A.; Verhaak, R.; Tirosh, I; Suva, M. L. 分享 收藏
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LONGITUDINAL SINGLE-CELL ANALYSES IDENTIFY DRIVERS OF GENETIC, EPIGENOMIC, AND CELLULAR EVOLUTION IN IDH-MUTANT GLIOMA Johnson, Kevin; Spitzer, Avishay; Varn, Frederick; Nomura, Masashi; Garofano, Luciano; Chowdhury, Tamrin; Anderson, Kevin; D'Angelo, Fulvio; Bussema, Lillian; Gritsch, Simon; Oh, Young Taek; Moon, Hyo-Eun; Paek, Sun Ha; Bielle, Franck; Laurenge, Alice; Di Stefano, Anna-Luisa; Mathon, Bertrand; Picca, Alberto; Sanson, Marc; Lipsa, Anuja; Hertel, Frank; Zhao, Zheng; Wang, Qianghu; Jiang, Tao; Hermes, Beth; Sanai, Nader; Golebiewska, Anna; Niclou, Simone; Huse, Jason; Yung, W. K. Alfred; Lasorella, Anna; Suva, Mario; Iavarone, Antonio; Tirosh, Itay; Verhaak, Roel 分享 收藏
MULTI-OMICS AND DRUG RESPONSE ASSESSMENTS IN LONGITUDINAL PATIENT AVATARS UNVEIL PATIENT-SPECIFIC RECURRENCE TRAJECTORIES AND DRUG SUSCEPTIBILITIES IN GLIOBLASTOMA Lipsa, A.; Nosirov, B.; Ermini, L.; Hau, A.; Klein, E.; Yabo, Y. A.; Mittelbronn, M.; Hertel, F.; Nazarov, P., V; Niclou, S. P.; Golebiewska, A. 分享 收藏
LONGITUDINAL SINGLE-CELL ANALYSES IDENTIFY DRIVERS OF GENETIC, EPIGENOMIC, AND CELLULAR EVOLUTION IN IDH-MUTANT GLIOMA Johnson, K. C.; Spitzer, A.; Varn, F. S.; Nomura, M.; Garofano, L.; Chowdhury, T.; Anderson, K. J.; D'Angelo, F.; Bussema, L.; Gritsch, S.; Oh, Y.; Moon, H.; Paek, S.; Bielle, F.; Laurenge, A.; Di Stefano, A.; Mathon, B.; Picca, A.; Sanson, M.; Lipsa, A.; Hertel, F.; Zhao, Z.; Wang, Q.; Jiang, T.; Hermes, B.; Sanai, N.; Golebiewska, A.; Niclou, S. P.; Huse, J.; Yung, W.; Lasorella, A.; Suva, M. L.; Iavarone, A.; Tirosh, I; Verhaak, R. G. 分享 收藏
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts Yabo, Yahaya A.; Moreno-Sanchez, Pilar M.; Pires-Afonso, Yolanda; Kaoma, Tony; Nosirov, Bakhtiyor; Scafidi, Andrea; Ermini, Luca; Lipsa, Anuja; Oudin, Anais; Kyriakis, Dimitrios; Grzyb, Kamil; Poovathingal, Suresh K.; Poli, Aurelie; Muller, Arnaud; Toth, Reka; Klink, Barbara; Berchem, Guy; Berthold, Christophe; Hertel, Frank; Mittelbronn, Michel; Heiland, Dieter H.; Skupin, Alexander; Nazarov, Petr V.; Niclou, Simone P.; Michelucci, Alessandro; Golebiewska, Anna 分享 收藏
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Impact of Formalin- and Cryofixation on Raman Spectra of Human Tissues and Strategies for Tumor Bank Inclusion Mirizzi, Giulia; Jelke, Finn; Pilot, Michel; Klein, Karoline; Klamminger, Gilbert Georg; Gerardy, Jean-Jacques; Theodoropoulou, Marily; Mombaerts, Laurent; Husch, Andreas; Mittelbronn, Michel; Hertel, Frank; Kleine Borgmann, Felix Bruno 分享 收藏
Computational Assessment of Spectral Heterogeneity within Fresh Glioblastoma Tissue Using Raman Spectroscopy and Machine Learning Algorithms Klein, Karoline; Klamminger, Gilbert Georg; Mombaerts, Laurent; Jelke, Finn; Arroteia, Isabel Fernandes; Slimani, Redouane; Mirizzi, Giulia; Husch, Andreas; Frauenknecht, Katrin B. M.; Mittelbronn, Michel; Hertel, Frank; Kleine Borgmann, Felix B. 分享 收藏
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Comparative analysis of deeply phenotyped GBM cohorts of 'short-term' and 'long-term' survivors Biswas, Archita; Salvucci, Manuela; Connor, Kate; Dussmann, Heiko; Carberry, Steven; Fichtner, Michael; King, Ellen; Murphy, Brona; O'Farrell, Alice C.; Cryan, Jane; Beausang, Alan; Heffernan, Josephine; Cremona, Mattia; Hennessy, Bryan T.; Clerkin, James; Sweeney, Kieron J.; MacNally, Steve; Brett, Francesca; O'Halloran, Philip; Bacon, Orna; Furney, Simon; Verreault, Maite; Quissac, Emie; Bielle, Franck; Ahmed, Mohammed H.; Idbaih, Ahmed; Leenstra, Sieger; Ntafoulis, Ioannis; Fabro, Federica; Lamfers, Martine; Golebiewska, Anna; Hertel, Frank; Niclou, Simone P.; Yen, Romain Tching Chi; Kremer, Andreas; Dilcan, Gonca; Lodi, Francesca; Arijs, Ingrid; Lambrechts, Diether; Purushothama, Manasa Kalya; Kel, Alexander; Byrne, Annette T.; Prehn, Jochen H. M. 分享 收藏
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Pharmacogenomics profiling of gliomas for precision medicine Lipsa, A.; Hau, A.; Ermini, L.; Toth, R.; Oudin, A.; Klink, B.; Hertel, F.; Mittelbronn, M.; Golebiewska, A.; Niclou, S. 分享 收藏
Generalising from conventional pipelines using deep learning in high-throughput screening workflows Garcia Santa Cruz, Beatriz; Slter, Jan; Gomez-Giro, Gemma; Saraiva, Claudia; Sabate-Soler, Sonia; Modamio, Jennifer; Barmpa, Kyriaki; Schwamborn, Jens Christian; Hertel, Frank; Jarazo, Javier; Husch, Andreas 分享 收藏
Intraoperative discrimination of native meningioma and dura mater by Raman spectroscopy Jelke, Finn; Mirizzi, Giulia; Borgmann, Felix Kleine; Husch, Andreas; Slimani, Redouane; Klamminger, Gilbert Georg; Klein, Karoline; Mombaerts, Laurent; Gerardy, Jean-Jacques; Mittelbronn, Michel; Hertel, Frank 分享 收藏
Application of Raman spectroscopy for detection of histologically distinct areas in formalin-fixed paraffinembedded glioblastoma Klamminger, Gilbert Georg; Gerardy, Jean-Jacques; Jelke, Finn; Mirizzi, Giulia; Slimani, Redouane; Klein, Karoline; Husch, Andreas; Hertel, Frank; Mittelbronn, Michel; Kleine-Borgmann, Felix B. 分享 收藏
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology Golebiewska, Anna; Hau, Ann-Christin; Oudin, Anais; Stieber, Daniel; Yabo, Yahaya A.; Baus, Virginie; Barthelemy, Vanessa; Klein, Eliane; Bougnaud, Sebastien; Keunen, Olivier; Wantz, May; Michelucci, Alessandro; Neirinckx, Virginie; Muller, Arnaud; Kaoma, Tony; Nazarov, Petr, V; Azuaje, Francisco; De Falco, Alfonso; Flies, Ben; Richart, Lorraine; Poovathingal, Suresh; Arns, Thais; Grzyb, Kamil; Mock, Andreas; Herold-Mende, Christel; Steino, Anne; Brown, Dennis; May, Patrick; Miletic, Hrvoje; Malta, Tathiane M.; Noushmehr, Houtan; Kwon, Yong-Jun; Jahn, Winnie; Klink, Barbara; Tanner, Georgette; Stead, Lucy F.; Mittelbronn, Michel; Skupin, Alexander; Hertel, Frank; Bjerkvig, Rolf; Niclou, Simone P. 分享 收藏
TARGETING EPIGENETIC PATHWAYS IN THE TREATMENT OF RECURRENT HIGH-GRADE GLIOMA Hau, A.; Houben, L.; Klein, E.; Oudin, A.; Stieber, D.; Flies, B.; Kaoma, T.; Azuaje, F.; Fritah, S.; Bjerkvig, R.; Hertel, F.; Mittelbronn, M.; Golebiewska, A.; Niclou, S. P. 分享 收藏
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