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D

Diether Lambrechts

KU Leuven
H指数:122
被引数:6.9万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Identification of STYXL1 as novel susceptibility gene for anthracycline-induced cardiotoxicity in breast cancer patients

鉴定STYXL1作为乳腺癌患者蒽环类药物诱导的心脏毒性的新型易感基因

Cardiovascular Research
IF13.3
2026-10-270
PRE
Alejandro Velasco-Ruiz, PhD; Rocío Núñez-Torres, PhD; Guillermo Pita, BSc; Raul Torres-Ruiz, PhD; Alberto Díaz-Talavera, PhD; Hugo Tejera-Perez, BSc; Hans Wildiers, MD, PhD; Diether Lambrechts, PhD; Sigrid Hatse, PhD; Danielle Delombaerde, PhD; Thomas Van Brussel, MSC; M Rosario Alonso, MSC; Nuria Álvarez, MSC; Belén Herráez, MSC; Teresa Alonso-Gordoa, MD, PhD; Pedro Talavera-Calle, MD, PhD; José María Serrano-Antolín, MD, PhD; Ramón Campos-Olivas, PhD; Mercedes Robledo, PhD; Christof Vulsteke, MD, PhD; Sandra Rodríguez-Perales, PhD; Pilar Zamora, MD, PhD; Teresa López-Fernández, MD, PhD; Anna Gonzalez-Neira, PhD
Evaluating the NFPp10a/NF5310 glioblastoma model as a faithful avatar for screening tumour microenvironment–targeted therapies

评估NFPp10a/NF5310胶质母细胞瘤模型作为忠实替身用于筛选肿瘤微环境靶向疗法

Communications Biology
IF5.1
2026-09-040
OAAI
Kieron White; James Clerkin; Liam P. Shiels; Kieron Sweeney; Mohannad Dabbour; Alice C. O’Farrell; Maïté Verreault; Thomas Van Brussel; Ingrid Arijs; Suzanne Murphy; Evin M. Haworth; Christopher Van Hessche; Gautam Shankar; Joana Beyer; Patrick Dicker; Stephen G. Maher; Laure Marignol; Jack P. Gleeson; David O’Brien; Diether Lambrechts; Jochen H. M. Prehn; Ahmed Idbaih; Frederik De Smet; Kate Connor; Annette T. Byrne
Pulmonary inflammation in severe pneumonia is characterised by compartmentalised and mechanistically distinct sub-phenotypes

重症肺炎中的肺炎症以分区域且机制不同的亚表型为特征

Nature Communications
IF15.7
2026-06-230
OAAI
Mark Jeffrey; Josefin Bartholdson Scott; Shyamanova Mazumdar; Richard J. White; Ellen Higginson; Mailis Maes; Sally Forrest; Joana Pereira-Dias; Surendra Parmar; Emma Heasman-Hunt; Martin D. Curran; Petra Polgarova; Jurgen Herre; Els Wauters; Diether Lambrechts; Pierre Van Mol; Cato Jacobs; Joost Wauters; Emma E. Davenport; Stephen Baker; Gordon Dougan; Vilas Navapurkar; Andrew Conway Morris
Pan-cancer single-cell atlases of mouse and human tumor-associated dendritic cells

小鼠和人类肿瘤相关树突状细胞的泛癌单细胞图谱

Nature Communications
IF15.7
2026-05-300
OAAI
Aarushi A. Caro; Daliya Kancheva; Eva Hadadi; Bram Boeckx; Clint De Nolf; Pauline M. R. Bardet; Kevin Verstaen; Luqing Li; Lobna Oueslati; Nil Figueras-Duch; Yvon Elkrim; Niels Vandamme; Sofie Deschoemaeker; Arnaud Blomme; Pierre Close; Sophie Janssens; Michele De Palma; Diether Lambrechts; An Coosemans; Damya Laoui
Integrated multi-omics identifies distinct macrophage alterations during progression of metabolic dysfunction-associated steatohepatitis

整合多组学分析揭示代谢功能障碍相关脂肪性肝炎进展过程中巨噬细胞的特异性改变

Nature Genetics
IF29
2026-05-180
OAAI
Markus Boesch; Seray Anak; Dania El Abyad; Tessa Ostyn; Asier Antoranz; Trieu My Van; Daniel Newhouse; Caitlyn Myers; Lukas Van Melkebeke; Jeremy Palmer; Najmeh Saffarzadeh; Jonathan Sai-Hong Chui; Rita Feio-Azevedo; Lena Smets; Gautam Shankar; Nikolina Dubroja Lakić; Paula Longás Calvo; Thierry Voet; James Clark; Simon Cockell; Matthias Lannoo; Ellen Deleus; Joris Jaekers; Halit Topal; Baki Topal; Kai Markus Schneider; Michele Vacca; Michael Allison; Mattias Ekstedt; Jerome Boursier; Elisabetta Bugianesi; Vlad Ratziu; Frederik De Smet; Bram Boeckx; Ann K. Daly; Jörn M. Schattenberg; Jef Verbeek; Francesca Bosisio; Diether Lambrechts; Tania Roskams; Carolin V. Schneider; Sven Francque; Hannelie Korf; Anetta Härtlova; Dina Tiniakos; Quentin M. Anstee; Schalk van der Merwe; Olivier Govaere
A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer

一种基于机器学习的多模态数据融合方法流程，用于贝伐珠单抗治疗转移性结直肠癌的预后风险分析

Scientific Reports
IF3.9
2026-04-010
OAAI
Thomas, Valentina; Nyamundanda, Gift; Larkeryd, Adrian; Hari, P. S.; Miller, Ian S.; Venken, Tom; Smeets, Dominiek; Boeckx, Bram; Betge, Johannes; Ebert, Matthias P. A.; Gaiser, Timo; Murphy, Verena; Kay, Elaine; Verheul, Henk M.; O'Farrell, Alice C.; Cremolini, Chiara; Marmorino, Federica; Gallagher, William M.; Barat, Ana; Klinger, Rut; Fender, Bozena; Ylstra, Bauke; van Grieken, Nicole; McNamara, Deborah A.; Hennessy, Bryan T.; Das, Sudipto; Moran, Bruce; O'Connor, Darran P.; Dienstmann, Rodrigo; Lambrechts, Diether; Prehn, Jochen H. M.; Sadanandam, Anguraj; Byrne, Annette T.
Prognostic and Predictive Value of the Clearseq1-4 Tumor Microenvironment Classification in Localized and Metastatic Clear-Cell Renal Cell Carcinoma

在局限性和转移性透明细胞肾细胞癌中Clearseq1-4肿瘤微环境分类的预后和预测价值

Cancer Research Communications
IF0
2026-04-010
PRE
Kinget, Lisa; McTaggart, Edward Scott; Demeulenaere, Octavie; Roussel, Eduard; Boeckx, Bram; Zucman-Rossi, Jessica; Couchy, Gabrielle; Vandermeulen, Henri; De Wever, Liesbeth; Baldewijns, Marcella; Wozniak, Agnieszka; Joniau, Steven; Lambrechts, Diether; Naulaerts, Stefan; Garg, Abhishek D.; Verbiest, Annelies; Albersen, Maarten; Beuselinck, Benoit
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

作者更正: PHGDH异质性增强癌细胞的传播和转移

Nature
IF48.5
2026-02-050
PRE
Matteo Rossi; Patricia Altea-Manzano; Margherita Demicco; Ginevra Doglioni; Laura Bornes; Marina Fukano; Anke Vandekeere; Alejandro M. Cuadros; Juan Fernández-García; Carla Riera-Domingo; Cristina Jauset; Mélanie Planque; H. Furkan Alkan; David Nittner; Dongmei Zuo; Lindsay A. Broadfield; Sweta Parik; Antonino Alejandro Pane; Francesca Rizzollo; Gianmarco Rinaldi; Tao Zhang; Shao Thing Teoh; Arin B. Aurora; Panagiotis Karras; Ines Vermeire; Dorien Broekaert; Joke Van Elsen; Maximilian M. L. Knott; Martin F. Orth; Sofie Demeyer; Guy Eelen; Lacey E. Dobrolecki; Ayse Bassez; Thomas Van Brussel; Karl Sotlar; Michael T. Lewis; Harald Bartsch; Manfred Wuhrer; Peter van Veelen; Peter Carmeliet; Jan Cools; Sean J. Morrison; Jean-Christophe Marine; Diether Lambrechts; Massimiliano Mazzone; Gregory J. Hannon; Sophia Y. Lunt; Thomas G. P. Grünewald; Morag Park; Jacco van Rheenen; Sarah-Maria Fendt
Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain

贝伐珠单抗用于染色体不稳定性转移性结直肠癌：德国、爱尔兰和西班牙一种新型精准治疗方法的成本效益分析

PharmacoEconomics
IF4.6
2026-02-040
PRE
Jonathan Briody; Ian S. Miller; James F. O’Mahony; Lesley Tilson; Alice C. O’Farrell; Qiushi Chen; Verena Murphy; Orla Casey; Nadine Schulte; Matthias P. Ebert; Jochen H. M. Prehn; Diether Lambrechts; Bauke Ylstra; Rodrigo Dienstmann; Annette T. Byrne; Kathleen Bennett
ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer

ctDNA在转移性乳腺癌患者七种体液中的检测性与代表性

Nature Communications
IF15.7
2025-12-020
OAAI
François Richard; Marion Maetens; Karen Van Baelen; Kristien Borremans; Josephine Van Cauwenberge; Gitte Zels; Emma Rousseau; Tatjana Geukens; Maxim De Schepper; Amena Mahdami; Evy Vanderheyden; Thomas Van Brussel; Ha-Linh Nguyen; Anirudh Pabba; Sophia Leduc; Hava Izci; Imane Bachir; Camille Carette; Sigrid Hatse; Madita Nysen; Peter Vermeulen; Bram Boeckx; Diether Lambrechts; Elia Biganzoli; Patrick Neven; Hans Wildiers; Wouter Van Den Bogaert; Jonas Demeulemeester; Giuseppe Floris; Christine Desmedt
Single-cell mapping of alternative splicing linked to checkpoint immunotherapy response

单细胞图谱分析：与免疫检查点疗法反应相关的选择性剪接

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-260
PRE
Xiong, Jieyi; Bricard, Orian; Arijs, Ingrid; Demeulemeester, Jonas; Gu, Chen; Thienpont, Bernard; Daaboul, Danie; Bassez, Ayse; Bechter, Oliver; Pozniak, Joanna; Vos, Hanne; Nevelsteen, Ines; Torfs, Sofie; Santos, Sara Aibar; Lan, Qing; Hou, Yong; Van oudenhove, Lore; Boons, Gitta; Qian, Junbin; Aerts, Stein; Smeets, Ann; Marine, Jean-Christophe; Lambrechts, Diether
Progression-free survival for unresectable non-metastatic locally advanced pancreatic cancer after surgical microwave ablation plus durvalumab and tremelimumab: phase-2 non-randomized prospective clinical trial

不可切除的非转移性局部晚期胰腺癌在行手术治疗联合微波消融、durvalumab和tremelimumab后的无进展生存期：二期非随机前瞻性临床研究

Communications Medicine
IF6.3
2025-11-180
OAAI
Halit Topal; Tom Venken; Ayse Bassez; Gabriela Chiritescu; Eric Van Cutsem; Schalk van der Merwe; Diether Lambrechts; Baki Topal
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction

欧洲血统人群的多基因得分分布差异: 对乳腺癌风险预测的影响

BREAST CANCER RESEARCH
IF5.6
2024-12-290
OAAI
Yiangou, Kristia; Mavaddat, Nasim; Dennis, Joe; Zanti, Maria; Wang, Qin; Bolla, Manjeet K.; Abubakar, Mustapha; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Arndt, Volker; Aronson, Kristan J.; Augustinsson, Annelie; Baten, Adinda; Behrens, Sabine; Bermisheva, Marina; de Gonzalez, Amy Berrington; Bialkowska, Katarzyna; Boddicker, Nicholas; Bodelon, Clara; Bogdanova, Natalia V.; Bojesen, Stig E.; Brantley, Kristen D.; Brauch, Hiltrud; Brenner, Hermann; Camp, Nicola J.; Canzian, Federico; Castelao, Jose E.; Cessna, Melissa H.; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chung, Wendy K.; Colonna, Sarah V.; Couch, Fergus J.; Cox, Angela; Cross, Simon S.; Czene, Kamila; Daly, Mary B.; Devilee, Peter; Doerk, Thilo; Dunning, Alison M.; Eccles, Diana M.; Eliassen, A. Heather; Engel, Christoph; Eriksson, Mikael; Evans, D. Gareth; Fasching, Peter A.; Fletcher, Olivia; Flyger, Henrik; Fritschi, Lin; Gago-Dominguez, Manuela; Gentry-Maharaj, Aleksandra; Gonzalez-Neira, Anna; Guenel, Pascal; Hahnen, Eric; Haiman, Christopher A.; Hamann, Ute; Hartikainen, Jaana M.; Ho, Vikki; Hodge, James; Hollestelle, Antoinette; Honisch, Ellen; Hooning, Maartje J.; Hoppe, Reiner; Hopper, John L.; Howell, Sacha; Howell, Anthony; Jakovchevska, Simona; Jakubowska, Anna; Jernstroem, Helena; Johnson, Nichola; Kaaks, Rudolf; Khusnutdinova, Elza K.; Kitahara, Cari M.; Koutros, Stella; Kristensen, Vessela N.; Lacey, James V.; Lambrechts, Diether; Lejbkowicz, Flavio; Lindblom, Annika; Lush, Michael; Mannermaa, Arto; Mavroudis, Dimitrios; Menon, Usha; Murphy, Rachel A.; Nevanlinna, Heli; Obi, Nadia; Offit, Kenneth; Park-Simon, Tjoung-Won; Patel, Alpa V.; Peng, Cheng; Peterlongo, Paolo; Pita, Guillermo; Plaseska-Karanfilska, Dijana; Pylkaes, Katri; Radice, Paolo; Rashid, Muhammad U.; Rennert, Gad; Roberts, Eleanor; Rodriguez, Juan; Romero, Atocha; Rosenberg, Efraim H.; Saloustros, Emmanouil; Sandler, Dale P.; Sawyer, Elinor J.; Schmutzler, Rita K.; Scott, Christopher G.; Shu, Xiao-Ou; Southey, Melissa C.; Stone, Jennifer; Taylor, Jack A.; Teras, Lauren R.; van de Beek, Irma; Willett, Walter; Winqvist, Robert; Zheng, Wei; Vachon, Celine M.; Schmidt, Marjanka K.; Hall, Per; MacInnis, Robert J.; Milne, Roger L.; Pharoah, Paul D. P.; Simard, Jacques; Antoniou, Antonis C.; Easton, Douglas F.; Michailidou, Kyriaki
Germline copy number variants and endometrial cancer risk

生殖细胞拷贝数变异与子宫内膜癌风险

HUMAN GENETICS
IF3.6
2024-11-040
OAAI
Stylianou, Cassie E.; Wiggins, George A. R.; Lau, Vanessa L.; Dennis, Joe; Shelling, Andrew N.; Wilson, Michelle; Sykes, Peter; Amant, Frederic; Annibali, Daniela; De Wispelaere, Wout; Easton, Douglas F.; Fasching, Peter A.; Glubb, Dylan M.; Goode, Ellen L.; Lambrechts, Diether; Pharoah, Paul D. P.; Scott, Rodney J.; Tham, Emma; Tomlinson, Ian; Bolla, Manjeet K.; Couch, Fergus J.; Czene, Kamila; Doerk, Thilo; Dunning, Alison M.; Fletcher, Olivia; Garcia-Closas, Montserrat; Hoppe, Reiner; Jernstrom, Helena; Kaaks, Rudolf; Michailidou, Kyriaki; Obi, Nadia; Southey, Melissa C.; Stone, Jennifer; Wang, Qin; Spurdle, Amanda B.; O'Mara, Traacy A.; Pearson, John; Walker, Logan C.

研究方向

暂未获取到该数据
G
Georgia Chenevix‐Trench
H 指数:115论文数:997被引数:7.0万
M
Montserrat García‐Closas
H 指数:0论文数:23被引数:0
B
Bram Boeckx
H 指数:41论文数:240被引数:1.3万
P
Peter A. Fasching
H 指数:121论文数:2,055被引数:7.8万
G
Graham G. Giles
H 指数:164论文数:2,399被引数:12.2万
S
Stig E. Bojesen
H 指数:100论文数:708被引数:4.6万
H
Hermann Brenner
H 指数:202论文数:3,279被引数:32.3万
M
Melissa C. Southey
H 指数:121论文数:1,251被引数:6.6万
A
Angela Cox
H 指数:89论文数:534被引数:3.5万
H
Hoda Anton‐Culver
H 指数:111论文数:885被引数:5.2万