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Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; de Angelis, Martin Hrabe; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Goetz, Alexander; Amarie, Oana, V; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; da Silva-Buttkus, Patricia; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie 分享 收藏
Murine tissue actor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality Sluka, Susanna H. M.; Staempfli, Simon F.; Akhmedov, Alexander; Rodewald, Tanja Klein; Sanz-Moreno, Adrian; Horsch, Marion; Grest, Paula; Rothmeier, Andrea S.; Rathkolb, Birgit; Schrewe, Anja; Beckers, Johannes; Neff, Frauke; Wolf, Eckhard; Camici, Giovanni G.; Fuchs, Helmut; Durner, Valerie Gailus; de Angelis, Martin Hrabe; Luescher, Thomas F.; Ruf, Wolfram; Tanner, Felix C. 分享 收藏
Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1I27N mutant mice Kumar, Sudhir; Rathkolb, Birgit; Sabrautzki, Sibylle; Krebs, Stefan; Kemter, Elisabeth; Becker, Lore; Beckers, Johannes; Bekeredjian, Raffi; Brommage, Robert; Calzada-Wack, Julia; Garrett, Lillian; Hoelter, Sabine M.; Horsch, Marion; Klingenspor, Martin; Klopstock, Thomas; Moreth, Kristin; Neff, Frauke; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Wolf, Eckhard; Aigner, Bernhard 分享 收藏
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression 新型转基因小鼠的广泛表型表征揭示了由于间充质hGH小基因表达而引起的生理学多效性扰动 Kaklamanos, Aimilios; Rozman, Jan; Roulis, Manolis; Karagianni, Niki; Armaka, Maria; Wu, Moya; Brachthaeuser, Laura; Calzada-Wack, Julia; Horsch, Marion; Beckers, Johannes; Rathkolb, Birgit; Adler, Thure; Neff, Frauke; Wolf, Eckhard; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Kollias, George 分享 收藏
Cardioprotection and lifespan extension by the natural polyamine spermidine 天然多胺亚精胺的心脏保护和寿命延长 Eisenberg, Tobias; Abdellatif, Mahmoud; Schroeder, Sabrina; Primessnig, Uwe; Stekovic, Slaven; Pendl, Tobias; Harger, Alexandra; Schipke, Julia; Zimmermann, Andreas; Schmidt, Albrecht; Tong, Mingming; Ruckenstuhl, Christoph; Dammbrueck, Christopher; Gross, Angelina S.; Herbst, Viktoria; Magnes, Christoph; Trausinger, Gert; Narath, Sophie; Meinitzer, Andreas; Hu, Zehan; Kirsch, Alexander; Eller, Kathrin; Carmona-Gutierrez, Didac; Buettner, Sabrina; Pietrocola, Federico; Knittelfelder, Oskar; Schrepfer, Emilie; Rockenfeller, Patrick; Simonini, Corinna; Rahn, Alexandros; Horsch, Marion; Moreth, Kristin; Beckers, Johannes; Fuchs, Helmut; Gailus-Durner, Valerie; Neff, Frauke; Janik, Dirk; Rathkolb, Birgit; Rozman, Jan; de Angelis, Martin Hrabe; Moustafa, Tarek; Haemmerle, Guenter; Mayr, Manuel; Willeit, Peter; von Frieling-Salewsky, Marion; Pieske, Burkert; Scorrano, Luca; Pieber, Thomas; Pechlaner, Raimund; Willeit, Johann; Sigrist, Stephan J.; Linke, Wolfgang A.; Muehlfeld, Christian; Sadoshima, Junichi; Dengjel, Joern; Kiechl, Stefan; Kroemer, Guido; Sedej, Simon; Madeo, Frank 分享 收藏
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis Halama, Anna; Horsch, Marion; Kastenmueller, Gabriele; Moeller, Gabriele; Kumar, Pankaj; Prehn, Cornelia; Laumen, Helmut; Hauner, Hans; de Angelis, Martin Hrabe; Beckers, Johannes; Suhre, Karsten; Adamski, Jerzy 分享 收藏
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers Deng, Tao; Zhu, Z. Iris; Zhang, Shaofei; Postnikov, Yuri; Huang, Di; Horsch, Marion; Furusawa, Takashi; Beckers, Johannes; Rozman, Jan; Klingenspor, Martin; Amarie, Oana; Graw, Jochen; Rathkolb, Birgit; Wolf, Eckhard; Adler, Thure; Busch, Dirk H.; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; van der Velde, Arjan; Tessarollo, Lino; Ovcherenko, Ivan; Landsman, David; Bustin, Michael 分享 收藏
Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels Rathkolb, Birgit; Klempt, Martina; Sabrautzki, Sibylle; Michel, Dian; Klaften, Matthias; Laufs, Juergen; Sedlmeier, Reinhard; Hans, Wolfgang; Fuchs, Helmut; Muckenthaler, Martina U.; Horsch, Marion; Campagna, Dean R.; Fleming, Mark; de Angelis, Martin Hrabe; Wolf, Eckhard; Aigner, Bernhard 分享 收藏
MiR-34a deficiency accelerates medulloblastoma formation in vivo MiR-34a缺乏加速体内髓母细胞瘤的形成 Thor, Theresa; Kuenkele, Annette; Pajtler, Kristian W.; Wefers, Annika K.; Stephan, Harald; Mestdagh, Pieter; Heukamp, Lukas; Hartmann, Wolfgang; Vandesompele, Jo; Sadowski, Natalie; Becker, Lore; Garrett, Lillian; Hoelter, Sabine M.; Horsch, Marion; Calzada-Wack, Julia; Klein-Rodewald, Tanja; Racz, Ildiko; Zimmer, Andreas; Beckers, Johannes; Neff, Frauke; Klopstock, Thomas; Antonellis, Pasqualino De; Zollo, Massimo; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Schueller, Ulrich; de Angelis, Martin Hrabe; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes H. 分享 收藏
Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation Gewies, Andreas; Gorka, Oliver; Bergmann, Hanna; Pechloff, Konstanze; Petermann, Franziska; Jeltsch, Katharina M.; Rudelius, Martina; Kriegsmann, Mark; Weichert, Wilko; Horsch, Marion; Beckers, Johannes; Wurst, Wolfgang; Heikenwalder, Mathias; Korn, Thomas; Heissmeyer, Vigo; Ruland, Juergen 分享 收藏
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Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43 Stribl, Carola; Samara, Aladin; Truembach, Dietrich; Peis, Regina; Neumann, Manuela; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Rathkolb, Birgit; Wolf, Eckhard; Beckers, Johannes; Horsch, Marion; Neff, Frauke; Kremmer, Elisabeth; Koob, Sebastian; Reichert, Andreas S.; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Aichler, Michaela; Walch, Axel Karl; Becker, Lore; Klopstock, Thomas; Glasl, Lisa; Hoelter, Sabine M.; Wurst, Wolfgang; Floss, Thomas 分享 收藏
Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon Spieler, Derek; Kaffe, Maria; Knauf, Franziska; Bessa, Jose; Tena, Juan J.; Giesert, Florian; Schormair, Barbara; Tilch, Erik; Lee, Heekyoung; Horsch, Marion; Czamara, Darina; Karbalai, Nazanin; von Toerne, Christine; Waldenberger, Melanie; Gieger, Christian; Lichtner, Peter; Claussnitzer, Melina; Naumann, Ronald; Mueller-myhsok, Bertram; Torres, Miguel; Garrett, Lillian; Rozman, Jan; Klingenspor, Martin; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Beckers, Johannes; Hoelter, Sabine M.; Meitinger, Thomas; Hauck, Stefanie M.; Laumen, Helmut; Wurst, Wolfgang; Casares, Fernando; Luis Gomez-Skarmeta, Jose; Winkelmann, Juliane 分享 收藏
Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis Kahle, Melanie; Horsch, Marion; Fridrich, Barbara; Seelig, Anett; Schultheiss, Juergen; Leonhardt, Joern; Irmler, Martin; Beckers, Johannes; Rathkolb, Birgit; Wolf, Eckhard; Franke, Nicole; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Neschen, Susanne 分享 收藏
Rapamycin extends murine lifespan but has limited effects on aging Neff, Frauke; Flores-Dominguez, Diana; Ryan, Devon R.; Horsch, Marion; Schroeder, Susanne; Adler, Thure; Afonso, Luciana Caminha; Aguilar-Pimentel, Juan Antonio; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hettich, Moritz M.; Holtmeier, Richard; Hoelter, Sabine M.; Moreth, Kristin; Prehn, Cornelia; Puk, Oliver; Racz, Ildiko; Rathkolb, Birgit; Rozman, Jan; Naton, Beatrix; Ordemann, Rainer; Adamski, Jerzy; Beckers, Johannes; Bekeredjian, Raffi; Busch, Dirk H.; Ehninger, Gerhard; Graw, Jochen; Hoefler, Heinz; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Stypmann, Joerg; Wolf, Eckhard; Wurst, Wolfgang; Zimmer, Andreas; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Ehninger, Dan 分享 收藏
High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner Kugler, Jamie E.; Horsch, Marion; Huang, Di; Furusawa, Takashi; Rochman, Mark; Garrett, Lillian; Becker, Lore; Bohla, Alexander; Hoelter, Sabine M.; Prehn, Cornelia; Rathkolb, Birgit; Racz, Ildiko; Aguilar-Pimentel, Juan Antonio; Adler, Thure; Adamski, Jerzy; Beckers, Johannes; Busch, Dirk H.; Eickelberg, Oliver; Klopstock, Thomas; Ollert, Markus; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Garfinkel, Benny; Orly, Joseph; Ovcharenko, Ivan; Bustin, Michael 分享 收藏
SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities Ju, Limei; Wing, Jonathan; Taylor, Elaine; Brandt, Renata; Slijepcevic, Predrag; Horsch, Marion; Rathkolb, Birgit; Racz, Ildiko; Becker, Lore; Hans, Wolfgang; Adler, Thure; Beckers, Johannes; Rozman, Jan; Klingenspor, Martin; Wolf, Eckhard; Zimmer, Andreas; Klopstock, Thomas; Busch, Dirk H.; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; van der Horst, Gilbertus; Lehmann, Alan R. 分享 收藏
The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis Hochrath, Katrin; Krawczyk, Marcin; Goebel, Reinhild; Langhirt, Miriam; Rathkolb, Birgit; Micklich, Kateryna; Rozman, Jan; Horsch, Marion; Beckers, Johannes; Klingenspor, Martin; Fuchs, Helmut; Gailus-Durner, Valerie; Wolf, Eckhard; Acalovschi, Monica; Volmer, Dietrich A.; de Angelis, Martin Hrabe; Lammert, Frank 分享 收藏
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