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A 6-week randomized, double-blind, placebo-controlled, comparator referenced trial of vabicaserin in acute schizophrenia Shen, Joan H. Q.; Zhao, Yonggang; Rosenzweig-Lipson, Sharon; Popp, Danielle; Williams, Janet B. W.; Giller, Earl; Detke, Michael J.; Kane, John M. 分享 收藏
Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression Hughes, Z. A.; Neal, S. J.; Smith, D. L.; Rizzo, S. J. Sukoff; Pulicicchio, C. M.; Lotarski, S.; Lu, S.; Dwyer, J. M.; Brennan, J.; Olsen, M.; Bender, C. N.; Kouranova, E.; Andree, T. H.; Harrison, J. E.; Whiteside, G. T.; Springer, D.; O'Neil, S. V.; Leonard, S. K.; Schechter, L. E.; Dunlop, J.; Rosenzweig-Lipson, S.; Ring, R. H. 分享 收藏
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Synergism Between a Serotonin 5-HT2A Receptor (5-HT2AR) Antagonist and 5-HT2CR Agonist Suggests New Pharmacotherapeutics for Cocaine Addiction Cunningham, Kathryn A.; Anastasio, Noelle C.; Fox, Robert G.; Stutz, Sonja J.; Bubar, Marcy J.; Swinford, Sarah E.; Watson, Cheryl S.; Gilbertson, Scott R.; Rice, Kenner C.; Rosenzweig-Lipson, Sharon; Moeller, F. Gerard 分享 收藏
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The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise? Rizzo, Stacey J. Sukoff; Leonard, Sarah K.; Gilbert, Adam; Dollings, Paul; Smith, Deborah L.; Zhang, Mei-Yi; Di, Li; Platt, Brian J.; Neal, Sarah; Dwyer, Jason M.; Bender, Corey N.; Zhang, Jean; Lock, Tim; Kowal, Dianne; Kramer, Angela; Randall, Andrew; Huselton, Christine; Vishwanathan, Karthick; Tse, Susanna Y.; Butera, John; Ring, Robert H.; Rosenzweig-Lipson, Sharon; Hughes, Zoe A.; Dunlop, John 分享 收藏
Characterization of Vabicaserin (SCA-136), a Selective 5-Hydroxytryptamine 2C Receptor Agonist Dunlop, John; Watts, Stephanie W.; Barrett, James E.; Coupet, Joseph; Harrison, Boyd; Mazandarani, Hossein; Nawoschik, Stanley; Pangalos, Menelas N.; Ramamoorthy, Siva; Schechter, Lee; Smith, Deborah; Stack, Gary; Zhang, Jean; Zhang, Guoming; Rosenzweig-Lipson, Sharon 分享 收藏
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The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT1A Antagonists Childers, Wayne E., Jr.; Havran, Lisa M.; Asselin, Magda; Bicksler, James J.; Chong, Dan C.; Grosu, George T.; Shen, Zhongqi; Abou-Gharbia, Magid A.; Bach, Alvin C., III; Harrison, Boyd L.; Kagan, Natasha; Kleintop, Teresa; Magolda, Ronald; Marathias, Vasilios; Robichaud, Albert J.; Sabb, Annmarie L.; Zhang, Mei-Yi; Andree, Terrance H.; Aschmies, Susan H.; Beyer, Chad; Comery, Thomas A.; Day, Mark; Grauer, Steven M.; Hughes, Zoe A.; Rosenzweig-Lipson, Sharon; Platt, Brian; Pulicicchio, Claudine; Smith, Deborah E.; Sukoff-Rizzo, Stacy J.; Sullivan, Kelly M.; Adedoyin, Adedayo; Huselton, Christine; Hirst, Warren D. 分享 收藏
Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activation Beyer, Chad E.; Dwyer, Jason M.; Platt, Brian J.; Neal, Sarah; Luo, Bin; Ling, Huai-Ping; Lin, Qian; Mark, Robert J.; Rosenzweig-Lipson, Sharon; Schechter, Lee E. 分享 收藏
WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol-2(3H)-one]: A Novel Dopamine D2 Receptor Partial Agonist/Serotonin Reuptake Inhibitor with Preclinical Antipsychotic-Like and Antidepressant-Like Activity Brennan, Julie A.; Graf, Radka; Grauer, Steven M.; Navarra, Rachel L.; Pulicicchio, Claudine M.; Hughes, Zoe A.; Lin, Qian; Wantuch, Caitlin; Rosenzweig-Lipson, Sharon; Pruthi, Farhana; Lai, Margaret; Smith, Deborah; Goutier, Wouter; van de Neut, Martina; Robichaud, Albert J.; Rotella, David; Feenstra, Rolf W.; Kruse, Chris; Broqua, Pierre; Beyer, Chad E.; McCreary, Andrew C.; Pausch, Mark H.; Marquis, Karen L. 分享 收藏
Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonists Bernotas, Ronald C.; Lenicek, Steven; Antane, Schuyler; Cole, Derek C.; Harrison, Boyd L.; Robichaud, Albert J.; Zhang, Guo Ming; Smith, Deborah; Platt, Brian; Lin, Qian; Li, Ping; Coupet, Joseph; Rosenzweig-Lipson, Sharon; Beyer, Chad E.; Schechter, Lee E. 分享 收藏
The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: Negative implications for the use of a model in screening for mood stabilizers Kelly, Michele R.; Logue, Sheree F.; Dwyer, Jason M.; Beyer, Chad E.; Majchrowski, Heather; Cai, Zhang; Liu, Zhi; Adedoyin, Adedayo; Rosenzweig-Lipson, Sharon; Comery, Thomas A. 分享 收藏
Preclinical characterization of WAY-211612: a dual 5-HT uptake inhibitor and 5-HT1A receptor antagonist and potential novel antidepressant Beyer, C. E.; Lin, Q.; Platt, B.; Malberg, J.; Hornby, G.; Sullivan, K. M.; Smith, D. L.; Lock, T.; Mitchell, P. J.; Hatzenbuhler, N. T.; Evrard, D. A.; Harrison, B. L.; Magolda, R.; Pangalos, M. N.; Schechter, L. E.; Rosenzweig-Lipson, S.; Andree, T. H. 分享 收藏
WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics Grauer, Steven M.; Graf, Radka; Navarra, Rachel; Sung, Amy; Logue, Sheree F.; Stack, Gary; Huselton, Christine; Liu, Zhi; Comery, Thomas A.; Marquis, Karen L.; Rosenzweig-Lipson, Sharon 分享 收藏
ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities Liu, Feng; Grauer, Steve; Kelley, Cody; Navarra, Rachel; Graf, Radka; Zhang, Guoming; Atkinson, Peter J.; Popiolek, Michael; Wantuch, Caitlin; Khawaja, Xavier; Smith, Deborah; Olsen, Michael; Kouranova, Evguenia; Lai, Margaret; Pruthi, Farhana; Pulicicchio, Claudine; Day, Mark; Gilbert, Adam; Pausch, Mark H.; Brandon, Nicholas J.; Beyer, Chad E.; Comery, Tom A.; Logue, Sheree; Rosenzweig-Lipson, Sharon; Marquis, Karen L. 分享 收藏
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